AU2006287938A1 - Tricyclic 6-alkylidene-penems as class-D beta-Lactamases inhibitors - Google Patents

Tricyclic 6-alkylidene-penems as class-D beta-Lactamases inhibitors Download PDF

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Publication number
AU2006287938A1
AU2006287938A1 AU2006287938A AU2006287938A AU2006287938A1 AU 2006287938 A1 AU2006287938 A1 AU 2006287938A1 AU 2006287938 A AU2006287938 A AU 2006287938A AU 2006287938 A AU2006287938 A AU 2006287938A AU 2006287938 A1 AU2006287938 A1 AU 2006287938A1
Authority
AU
Australia
Prior art keywords
optionally substituted
oxo
ene
thia
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2006287938A
Other languages
English (en)
Inventor
Tarek Suhayl Mansour
Aranapakam Mudumbai Venkatesan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of AU2006287938A1 publication Critical patent/AU2006287938A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU2006287938A 2005-06-01 2006-05-25 Tricyclic 6-alkylidene-penems as class-D beta-Lactamases inhibitors Abandoned AU2006287938A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68622105P 2005-06-01 2005-06-01
US60/686,221 2005-06-01
PCT/US2006/020410 WO2007030166A2 (en) 2005-06-01 2006-05-25 TRICYCLIC 6-ALKYLIDENE-PENEMS AS CLASS-D β-LACTAMASES INHIBITORS

Publications (1)

Publication Number Publication Date
AU2006287938A1 true AU2006287938A1 (en) 2007-03-15

Family

ID=37836305

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006287938A Abandoned AU2006287938A1 (en) 2005-06-01 2006-05-25 Tricyclic 6-alkylidene-penems as class-D beta-Lactamases inhibitors

Country Status (14)

Country Link
US (1) US20060276446A1 (enExample)
EP (1) EP1885358A2 (enExample)
JP (1) JP2008542376A (enExample)
CN (1) CN101189010A (enExample)
AR (1) AR054467A1 (enExample)
AU (1) AU2006287938A1 (enExample)
BR (1) BRPI0611491A2 (enExample)
CA (1) CA2610478A1 (enExample)
GT (1) GT200600235A (enExample)
MX (1) MX2007015173A (enExample)
PE (1) PE20070010A1 (enExample)
SV (1) SV2007002555A (enExample)
TW (1) TW200716104A (enExample)
WO (1) WO2007030166A2 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
TW200716102A (en) * 2005-06-01 2007-05-01 Wyeth Corp Bicyclic 6-alkylidene-penems as class-D β -lactamases inhibitors
US8512789B2 (en) * 2005-11-23 2013-08-20 The Coca-Cola Company High-potency sweetener composition with dietary fiber and compositions sweetened therewith
US8524304B2 (en) 2005-11-23 2013-09-03 The Coca-Cola Company High-potency sweetener composition with probiotics/prebiotics and compositions sweetened therewith
US8945652B2 (en) 2005-11-23 2015-02-03 The Coca-Cola Company High-potency sweetener for weight management and compositions sweetened therewith
JP2012121809A (ja) * 2009-02-26 2012-06-28 Eisai R & D Management Co Ltd 多環式化合物の製造法およびその中間体
US20110288063A1 (en) * 2010-05-19 2011-11-24 Naeja Pharmaceutical Inc. Novel fused bridged bicyclic heteroaryl substituted 6-alkylidene penems as potent beta-lactamase inhibitors
CN104341345B (zh) * 2014-10-24 2016-03-23 海门海康生物医药科技有限公司 一种2-甲氧基-6-酮-5,6,7,8-四氢喹啉的合成方法
EP3936192B1 (en) 2019-03-06 2025-04-09 Daiichi Sankyo Company, Limited Pyrrolopyrazole derivative

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ285085A (en) * 1994-04-25 1998-04-27 Smithkline Beecham Plc Penem composition, pharmaceutical formulation containing a beta-lactamase inhibiting penem and a beta-lactam antibiotic
US20040132706A1 (en) * 2001-10-05 2004-07-08 Daniela Salvemini Composition comprising a catalyst for the dismutation of superoxide and use of the composition for preventing and treating hypotension
AR039476A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp Proceso para preparar derivados de 6-alquiliden penem
AR039475A1 (es) * 2002-05-01 2005-02-23 Wyeth Corp 6-alquiliden-penems triciclicos como inhibidores de beta-lactamasa
AR039774A1 (es) * 2002-05-01 2005-03-02 Wyeth Corp 6-alquiliden-penems biciclicos como inhibidores de beta-lactamasas
US20040132708A1 (en) * 2002-05-01 2004-07-08 Wyeth Process for preparing 6-alkylidene penem derivatives
TW200716102A (en) * 2005-06-01 2007-05-01 Wyeth Corp Bicyclic 6-alkylidene-penems as class-D β -lactamases inhibitors

Also Published As

Publication number Publication date
JP2008542376A (ja) 2008-11-27
BRPI0611491A2 (pt) 2010-12-21
WO2007030166A3 (en) 2007-05-24
WO2007030166A2 (en) 2007-03-15
CN101189010A (zh) 2008-05-28
GT200600235A (es) 2007-03-29
TW200716104A (en) 2007-05-01
CA2610478A1 (en) 2007-03-15
EP1885358A2 (en) 2008-02-13
SV2007002555A (es) 2007-02-02
AR054467A1 (es) 2007-06-27
US20060276446A1 (en) 2006-12-07
MX2007015173A (es) 2008-02-15
PE20070010A1 (es) 2007-01-12

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period