AU2005295517A1 - P27 ubiquitination assay and methods of use - Google Patents

P27 ubiquitination assay and methods of use Download PDF

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Publication number
AU2005295517A1
AU2005295517A1 AU2005295517A AU2005295517A AU2005295517A1 AU 2005295517 A1 AU2005295517 A1 AU 2005295517A1 AU 2005295517 A AU2005295517 A AU 2005295517A AU 2005295517 A AU2005295517 A AU 2005295517A AU 2005295517 A1 AU2005295517 A1 AU 2005295517A1
Authority
AU
Australia
Prior art keywords
ubiquitin
label
compound
ubiquitinated
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2005295517A
Other languages
English (en)
Inventor
Sarah Cox
Frank M. Mercurio
Weilin Xie
Shuichan Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Signal Pharmaceuticals LLC
Original Assignee
Signal Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Signal Pharmaceuticals LLC filed Critical Signal Pharmaceuticals LLC
Publication of AU2005295517A1 publication Critical patent/AU2005295517A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AU2005295517A 2004-10-15 2005-10-17 P27 ubiquitination assay and methods of use Abandoned AU2005295517A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61909204P 2004-10-15 2004-10-15
US60/619,092 2004-10-15
PCT/US2005/037171 WO2006044747A2 (en) 2004-10-15 2005-10-17 P27 ubiquitination assay and methods of use

Publications (1)

Publication Number Publication Date
AU2005295517A1 true AU2005295517A1 (en) 2006-04-27

Family

ID=36203595

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005295517A Abandoned AU2005295517A1 (en) 2004-10-15 2005-10-17 P27 ubiquitination assay and methods of use

Country Status (6)

Country Link
US (1) US20060194262A1 (cg-RX-API-DMAC7.html)
EP (1) EP1810008A4 (cg-RX-API-DMAC7.html)
JP (1) JP2008517278A (cg-RX-API-DMAC7.html)
AU (1) AU2005295517A1 (cg-RX-API-DMAC7.html)
CA (1) CA2584131A1 (cg-RX-API-DMAC7.html)
WO (1) WO2006044747A2 (cg-RX-API-DMAC7.html)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2087355B1 (en) * 2006-11-27 2014-09-24 Cisbio Bioassays Method for the detection of post-translational modifications
MX344555B (es) * 2007-05-08 2016-12-20 Hunter Douglas Ind Switzerland Sistema de color multivariado con aplicacion de textura.
US20100021941A1 (en) * 2008-07-25 2010-01-28 Progenra, Incorporated Methods of identifying modulators of ubiquitin ligases
GB201007185D0 (en) * 2010-04-29 2010-06-09 Iti Scotland Ltd Ubiquitination assay
AU2012239943B2 (en) * 2011-04-07 2016-09-22 The Scripps Research Institute High-throughput screening for compounds modulating expression of cellular macromolecules
CN103196877B (zh) * 2013-03-08 2015-06-03 刘小龙 基于均相时间分辨荧光的检测重金属含量的方法
CN104155452A (zh) * 2013-05-15 2014-11-19 复旦大学 一种检测细胞内蛋白质降解的方法
GB201415688D0 (en) * 2014-09-04 2014-10-22 Univ Edinburgh Method and Systems
ES2965761T3 (es) 2016-08-08 2024-04-16 Tech Innovation Momentum Fund Israel Limited Partnership Sistemas bacterianos para el análisis de polipéptidos ubiquitilados
WO2019030759A1 (en) 2017-08-08 2019-02-14 Technology Innovation Momentum Fund (Israel) Limited Partnership CHLORAMPHENICOL-RESISTANT TRUNCATED PROTEIN AND USES THEREOF

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011755A1 (en) * 1993-10-28 1995-05-04 Houston Advanced Research Center Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions
US5463564A (en) * 1994-09-16 1995-10-31 3-Dimensional Pharmaceuticals, Inc. System and method of automatically generating chemical compounds with desired properties
US6747128B2 (en) * 1997-08-20 2004-06-08 Gpc Biotech, Inc. Components of ubiquitin ligase complexes, and uses related thereto
US6413725B1 (en) * 1998-08-07 2002-07-02 California Institute Of Technology Biochemical assay to monitor the ubiquitin ligase activities of cullins
AU767507B2 (en) * 1998-08-28 2003-11-13 New York University Novel ubiquitin ligases as therapeutic targets
US6740495B1 (en) * 2000-04-03 2004-05-25 Rigel Pharmaceuticals, Inc. Ubiquitin ligase assay
AU2002243477B2 (en) * 2001-01-05 2007-12-20 New York University Methods to identify compounds useful for the treatment of proliferative and differentiative disorders
DE60220621T2 (de) * 2001-11-09 2008-03-06 Proteologics, Inc. Posh Nukleinsäure, Polypeptide und darauf bezogene Verfahren
AU2003241897A1 (en) * 2002-05-29 2003-12-12 Kyowa Hakko Kogyo Co., Ltd. Novel ubiquitin ligase

Also Published As

Publication number Publication date
EP1810008A2 (en) 2007-07-25
US20060194262A1 (en) 2006-08-31
WO2006044747A3 (en) 2006-10-12
EP1810008A4 (en) 2008-09-10
WO2006044747A2 (en) 2006-04-27
CA2584131A1 (en) 2006-04-27
JP2008517278A (ja) 2008-05-22

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Legal Events

Date Code Title Description
MK4 Application lapsed section 142(2)(d) - no continuation fee paid for the application