AU2005289741C1 - Drug-delivery endovascular stent and method for treating restenosis - Google Patents

Drug-delivery endovascular stent and method for treating restenosis Download PDF

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Publication number
AU2005289741C1
AU2005289741C1 AU2005289741A AU2005289741A AU2005289741C1 AU 2005289741 C1 AU2005289741 C1 AU 2005289741C1 AU 2005289741 A AU2005289741 A AU 2005289741A AU 2005289741 A AU2005289741 A AU 2005289741A AU 2005289741 C1 AU2005289741 C1 AU 2005289741C1
Authority
AU
Australia
Prior art keywords
drug
stent
coating
site
restenosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005289741A
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English (en)
Other versions
AU2005289741B2 (en
AU2005289741A1 (en
Inventor
Ronald E. Betts
Douglas R. Savage
John E. Shulze
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biosensors International Group Ltd
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Biosensors International Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosensors International Group Ltd filed Critical Biosensors International Group Ltd
Publication of AU2005289741A1 publication Critical patent/AU2005289741A1/en
Assigned to BIOSENSORS INTERNATIONAL GROUP, LTD. reassignment BIOSENSORS INTERNATIONAL GROUP, LTD. Request for Assignment Assignors: SUN BIOMEDICAL, LTD.
Publication of AU2005289741B2 publication Critical patent/AU2005289741B2/en
Application granted granted Critical
Publication of AU2005289741C1 publication Critical patent/AU2005289741C1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)
AU2005289741A 2004-09-24 2005-09-23 Drug-delivery endovascular stent and method for treating restenosis Ceased AU2005289741C1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61307104P 2004-09-24 2004-09-24
US60/613,071 2004-09-24
US11/232,598 2005-09-22
US11/232,598 US7901451B2 (en) 2004-09-24 2005-09-22 Drug-delivery endovascular stent and method for treating restenosis
PCT/US2005/034193 WO2006036801A2 (en) 2004-09-24 2005-09-23 Drug-delivery endovascular stent and method for treating restenosis

Publications (3)

Publication Number Publication Date
AU2005289741A1 AU2005289741A1 (en) 2006-04-06
AU2005289741B2 AU2005289741B2 (en) 2011-05-12
AU2005289741C1 true AU2005289741C1 (en) 2011-09-22

Family

ID=36100285

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005289741A Ceased AU2005289741C1 (en) 2004-09-24 2005-09-23 Drug-delivery endovascular stent and method for treating restenosis

Country Status (9)

Country Link
US (3) US7901451B2 (enExample)
EP (2) EP1796754B1 (enExample)
JP (2) JP4231089B2 (enExample)
CN (2) CN102283730B (enExample)
AT (2) ATE554807T1 (enExample)
AU (1) AU2005289741C1 (enExample)
DE (1) DE602005017414D1 (enExample)
ES (1) ES2333606T3 (enExample)
WO (1) WO2006036801A2 (enExample)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US7220276B1 (en) * 2000-03-06 2007-05-22 Surmodics, Inc. Endovascular graft coatings
US8741378B1 (en) 2001-06-27 2014-06-03 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device
WO2003002243A2 (en) 2001-06-27 2003-01-09 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US7169178B1 (en) * 2002-11-12 2007-01-30 Advanced Cardiovascular Systems, Inc. Stent with drug coating
KR20060028695A (ko) * 2003-06-16 2006-03-31 난양 테크놀러지컬 유니버시티 고분자 스텐트 및 이의 제조 방법
US8137397B2 (en) * 2004-02-26 2012-03-20 Boston Scientific Scimed, Inc. Medical devices
US8003122B2 (en) * 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
US7901451B2 (en) 2004-09-24 2011-03-08 Biosensors International Group, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US20070112421A1 (en) * 2005-11-14 2007-05-17 O'brien Barry Medical device with a grooved surface
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
WO2007140320A2 (en) * 2006-05-26 2007-12-06 Nanyang Technological University Implantable article, method of forming same and method for reducing thrombogenicity
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
US8771343B2 (en) 2006-06-29 2014-07-08 Boston Scientific Scimed, Inc. Medical devices with selective titanium oxide coatings
US8052743B2 (en) 2006-08-02 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis with three-dimensional disintegration control
ATE508708T1 (de) 2006-09-14 2011-05-15 Boston Scient Ltd Medizinprodukte mit wirkstofffreisetzender beschichtung
CA2663271A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
CA2663220A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
JP2010503489A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生体内分解性内部人工器官およびその製造方法
EP2399616A1 (en) 2006-09-15 2011-12-28 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis with biostable inorganic layers
EP2068962B1 (en) 2006-09-18 2013-01-30 Boston Scientific Limited Endoprostheses
US8067055B2 (en) * 2006-10-20 2011-11-29 Biosensors International Group, Ltd. Drug-delivery endovascular stent and method of use
CN101600463B (zh) * 2006-10-20 2015-01-07 生物传感器国际集团有限公司 药物释放型血管内支架及其使用方法
US20080097591A1 (en) * 2006-10-20 2008-04-24 Biosensors International Group Drug-delivery endovascular stent and method of use
US20080103584A1 (en) * 2006-10-25 2008-05-01 Biosensors International Group Temporal Intraluminal Stent, Methods of Making and Using
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US20090062910A1 (en) * 2006-11-16 2009-03-05 Shippy Iii James Lee Stent with differential timing of abluminal and luminal release of a therapeutic agent
CN101199873B (zh) * 2006-12-14 2013-06-19 乐普（北京）医疗器械股份有限公司 药物洗脱器械用纳米级孔洞药物释放结构及其制备方法
US8080055B2 (en) 2006-12-28 2011-12-20 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
WO2008125940A2 (en) * 2007-04-17 2008-10-23 Pfizer Products Inc. Nanoparticles comprising non-crystalline drug
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US9284409B2 (en) 2007-07-19 2016-03-15 Boston Scientific Scimed, Inc. Endoprosthesis having a non-fouling surface
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US8221822B2 (en) 2007-07-31 2012-07-17 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
EP2185103B1 (en) 2007-08-03 2014-02-12 Boston Scientific Scimed, Inc. Coating for medical device having increased surface area
JP2009050513A (ja) * 2007-08-28 2009-03-12 Olympus Medical Systems Corp ステント及びステントデリバリーシステム
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US20090076591A1 (en) * 2007-09-19 2009-03-19 Boston Scientific Scimed, Inc. Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface
US20100298925A1 (en) * 2007-10-31 2010-11-25 Chameleon Scientific Corporation Spinulose metal surfaces
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US8573150B2 (en) 2007-11-14 2013-11-05 Biosensors International Group, Ltd. Automated stent coating apparatus and method
US7833266B2 (en) 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
JP5581311B2 (ja) 2008-04-22 2014-08-27 ボストン サイエンティフィック サイムド，インコーポレイテッド 無機材料のコーティングを有する医療デバイス及びその製造方法
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
EP2303350A2 (en) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8206635B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US8206636B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US10898620B2 (en) 2008-06-20 2021-01-26 Razmodics Llc Composite stent having multi-axial flexibility and method of manufacture thereof
US7951193B2 (en) * 2008-07-23 2011-05-31 Boston Scientific Scimed, Inc. Drug-eluting stent
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
US8267992B2 (en) 2009-03-02 2012-09-18 Boston Scientific Scimed, Inc. Self-buffering medical implants
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US8955732B2 (en) 2009-08-11 2015-02-17 Covidien Lp Surgical stapling apparatus
US8276801B2 (en) 2011-02-01 2012-10-02 Tyco Healthcare Group Lp Surgical stapling apparatus
EP2338534A2 (de) * 2009-12-21 2011-06-29 Biotronik VI Patent AG Medizinisches Implantat, Beschichtungsverfahren sowie Implantationsverfahren
WO2011119573A1 (en) 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8685433B2 (en) 2010-03-31 2014-04-01 Abbott Cardiovascular Systems Inc. Absorbable coating for implantable device
US8632837B2 (en) * 2010-05-17 2014-01-21 Abbott Cardiovascular Systems Inc. Direct fluid coating of drug eluting balloon
US9101741B2 (en) 2010-05-17 2015-08-11 Abbott Laboratories Tensioning process for coating balloon
US8940356B2 (en) 2010-05-17 2015-01-27 Abbott Cardiovascular Systems Inc. Maintaining a fixed distance during coating of drug coated balloon
US8702650B2 (en) 2010-09-15 2014-04-22 Abbott Laboratories Process for folding of drug coated balloon
JP5713336B2 (ja) * 2010-08-12 2015-05-07 株式会社オプトニクス精密 ステント
US8647702B2 (en) 2011-06-10 2014-02-11 Abbott Laboratories Maintaining a fixed distance by providing an air cushion during coating of a medical device
CN102784418B (zh) * 2012-08-10 2014-04-16 中国医学科学院生物医学工程研究所 可程序性释放的生物药物纳米微孔血管支架及其制备方法与用途
WO2014087414A1 (en) 2012-12-03 2014-06-12 Amrita Vishwa Vidya Peetham University Metallic titanium -based cardiovascular stent with nano - structured surface and method of manufacturing thereof
US9814805B2 (en) * 2013-04-25 2017-11-14 Innovative Surface Technologies, Inc. Coatings for controlled release of highly water soluble drugs
US10744233B2 (en) 2016-02-24 2020-08-18 Innovative Surface Technologies, Inc. Crystallization inhibitor compositions for implantable urological devices
SG11201900602XA (en) * 2016-09-19 2019-02-27 Biotronik Ag Polymer-free drug eluting vascular stents
WO2018114992A1 (en) * 2016-12-22 2018-06-28 Biotronik Ag Drug releasing coatings for medical devices and methods of making same
AU2020415460A1 (en) 2019-12-24 2022-08-18 Encompass Vascular, Inc. Medical devices for fluid delivery
CN111760190B (zh) * 2020-06-30 2024-06-07 南方科技大学 一种可降解外支架及其制备方法和应用
EP4297837A4 (en) 2021-02-23 2025-01-15 Encompass Vascular, Inc. Medical devices for fluid delivery and methods of use and manufacture
EP4329855A4 (en) 2021-04-30 2025-03-26 Encompass Vascular, Inc. MEDICAL DEVICES FOR FLUID DELIVERY AND METHODS OF USE AND MANUFACTURE
CN113317879B (zh) * 2021-05-28 2022-06-07 郑州大学第一附属医院 一种预测肝硬化患者tips术后支架再狭窄的试剂盒

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020098278A1 (en) * 2000-10-31 2002-07-25 Cook Incorporated Coated implantable medical device
WO2003022807A2 (en) * 2001-09-10 2003-03-20 Abbott Laboratories Medical devices containing rapamycin analogs
WO2003090818A2 (en) * 2002-04-24 2003-11-06 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis

Family Cites Families (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA737247B (en) 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
US4374669A (en) * 1975-05-09 1983-02-22 Mac Gregor David C Cardiovascular prosthetic devices and implants with porous systems
US4885171A (en) 1978-11-03 1989-12-05 American Home Products Corporation Use of rapamycin in treatment of certain tumors
US4316885A (en) * 1980-08-25 1982-02-23 Ayerst, Mckenna And Harrison, Inc. Acyl derivatives of rapamycin
US4650803A (en) * 1985-12-06 1987-03-17 University Of Kansas Prodrugs of rapamycin
US5059211A (en) * 1987-06-25 1991-10-22 Duke University Absorbable vascular stent
US5527337A (en) * 1987-06-25 1996-06-18 Duke University Bioabsorbable stent and method of making the same
US5288771A (en) * 1988-06-15 1994-02-22 Kansai Paint Company, Limited Water-dispersible core-shell resin which exhibits excellent sagging resistance in coatings
US4990155A (en) * 1989-05-19 1991-02-05 Wilkoff Howard M Surgical stent method and apparatus
US5100899A (en) * 1989-06-06 1992-03-31 Roy Calne Methods of inhibiting transplant rejection in mammals using rapamycin and derivatives and prodrugs thereof
US5258020A (en) * 1990-09-14 1993-11-02 Michael Froix Method of using expandable polymeric stent with memory
US5163952A (en) 1990-09-14 1992-11-17 Michael Froix Expandable polymeric stent with memory and delivery apparatus and method
US6248129B1 (en) * 1990-09-14 2001-06-19 Quanam Medical Corporation Expandable polymeric stent with memory and delivery apparatus and method
CA2082410C (en) * 1991-03-08 2003-09-23 Hideo Tamai Luminal stent, holding structure therefor and device for attaching luminal stent
US5120842A (en) * 1991-04-01 1992-06-09 American Home Products Corporation Silyl ethers of rapamycin
US6515009B1 (en) * 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5151413A (en) 1991-11-06 1992-09-29 American Home Products Corporation Rapamycin acetals as immunosuppressant and antifungal agents
US5516781A (en) * 1992-01-09 1996-05-14 American Home Products Corporation Method of treating restenosis with rapamycin
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5288711A (en) 1992-04-28 1994-02-22 American Home Products Corporation Method of treating hyperproliferative vascular disease
US5540712A (en) * 1992-05-01 1996-07-30 Nitinol Medical Technologies, Inc. Stent and method and apparatus for forming and delivering the same
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
US5258389A (en) 1992-11-09 1993-11-02 Merck & Co., Inc. O-aryl, O-alkyl, O-alkenyl and O-alkynylrapamycin derivatives
US5342348A (en) * 1992-12-04 1994-08-30 Kaplan Aaron V Method and device for treating and enlarging body lumens
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
DE4303181A1 (de) * 1993-02-04 1994-08-11 Angiomed Ag Implantierbarer Katheter
US5441515A (en) * 1993-04-23 1995-08-15 Advanced Cardiovascular Systems, Inc. Ratcheting stent
US5824048A (en) 1993-04-26 1998-10-20 Medtronic, Inc. Method for delivering a therapeutic substance to a body lumen
US5464650A (en) 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
US5994341A (en) * 1993-07-19 1999-11-30 Angiogenesis Technologies, Inc. Anti-angiogenic Compositions and methods for the treatment of arthritis
SG64372A1 (en) * 1993-12-17 1999-04-27 Novartis Ag Rapamycin derivatives
US5362718A (en) 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
US5649977A (en) * 1994-09-22 1997-07-22 Advanced Cardiovascular Systems, Inc. Metal reinforced polymer stent
WO1996011720A1 (fr) * 1994-10-17 1996-04-25 Kabushikikaisha Igaki Iryo Sekkei Extenseur endovasculaire liberant un medicament
US5707385A (en) * 1994-11-16 1998-01-13 Advanced Cardiovascular Systems, Inc. Drug loaded elastic membrane and method for delivery
US6231600B1 (en) * 1995-02-22 2001-05-15 Scimed Life Systems, Inc. Stents with hybrid coating for medical devices
US6099562A (en) * 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US5609629A (en) * 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
CA2178541C (en) * 1995-06-07 2009-11-24 Neal E. Fearnot Implantable medical device
GB9606452D0 (en) * 1996-03-27 1996-06-05 Sandoz Ltd Organic compounds
US6019784A (en) * 1996-04-04 2000-02-01 Electroformed Stents, Inc. Process for making electroformed stents
US5713949A (en) * 1996-08-06 1998-02-03 Jayaraman; Swaminathan Microporous covered stents and method of coating
US5769884A (en) * 1996-06-27 1998-06-23 Cordis Corporation Controlled porosity endovascular implant
US6174329B1 (en) * 1996-08-22 2001-01-16 Advanced Cardiovascular Systems, Inc. Protective coating for a stent with intermediate radiopaque coating
US6099561A (en) * 1996-10-21 2000-08-08 Inflow Dynamics, Inc. Vascular and endoluminal stents with improved coatings
US5868781A (en) * 1996-10-22 1999-02-09 Scimed Life Systems, Inc. Locking stent
US6197013B1 (en) * 1996-11-06 2001-03-06 Setagon, Inc. Method and apparatus for drug and gene delivery
ZA9710342B (en) * 1996-11-25 1998-06-10 Alza Corp Directional drug delivery stent and method of use.
US5980972A (en) 1996-12-20 1999-11-09 Schneider (Usa) Inc Method of applying drug-release coatings
IT1289815B1 (it) * 1996-12-30 1998-10-16 Sorin Biomedica Cardio Spa Stent per angioplastica e relativo procedimento di produzione
WO1998036784A1 (en) 1997-02-20 1998-08-27 Cook Incorporated Coated implantable medical device
US6240616B1 (en) * 1997-04-15 2001-06-05 Advanced Cardiovascular Systems, Inc. Method of manufacturing a medicated porous metal prosthesis
US5843172A (en) 1997-04-15 1998-12-01 Advanced Cardiovascular Systems, Inc. Porous medicated stent
US6273913B1 (en) 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US6670398B2 (en) 1997-05-14 2003-12-30 Atherogenics, Inc. Compounds and methods for treating transplant rejection
AU8005198A (en) * 1997-06-09 1998-12-30 University Of British Columbia, The Improved fish feed and method of using same
US6203536B1 (en) * 1997-06-17 2001-03-20 Medtronic, Inc. Medical device for delivering a therapeutic substance and method therefor
EP1003444A4 (en) 1997-08-08 2004-07-28 Sunscope International Inc MICROPOROUS STENT AND IMPLANTATION DEVICE
US6159488A (en) 1997-08-14 2000-12-12 Agricultural Research Org. Ministry Of Agriculture (Gov.) Intracoronary stents containing quinazolinone derivatives
US6042606A (en) * 1997-09-29 2000-03-28 Cook Incorporated Radially expandable non-axially contracting surgical stent
US5972027A (en) 1997-09-30 1999-10-26 Scimed Life Systems, Inc Porous stent drug delivery system
US6156062A (en) 1997-12-03 2000-12-05 Ave Connaught Helically wrapped interlocking stent
US6190406B1 (en) * 1998-01-09 2001-02-20 Nitinal Development Corporation Intravascular stent having tapered struts
US6129755A (en) 1998-01-09 2000-10-10 Nitinol Development Corporation Intravascular stent having an improved strut configuration
US6623521B2 (en) 1998-02-17 2003-09-23 Md3, Inc. Expandable stent with sliding and locking radial elements
US7208011B2 (en) * 2001-08-20 2007-04-24 Conor Medsystems, Inc. Implantable medical device with drug filled holes
US7713297B2 (en) * 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
US20010029351A1 (en) 1998-04-16 2001-10-11 Robert Falotico Drug combinations and delivery devices for the prevention and treatment of vascular disease
US6153252A (en) 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
US6652581B1 (en) 1998-07-07 2003-11-25 Boston Scientific Scimed, Inc. Medical device with porous surface for controlled drug release and method of making the same
US6096175A (en) * 1998-07-17 2000-08-01 Micro Therapeutics, Inc. Thin film stent
US20020038146A1 (en) * 1998-07-29 2002-03-28 Ulf Harry Expandable stent with relief cuts for carrying medicines and other materials
CA2340652C (en) 1998-08-20 2013-09-24 Cook Incorporated Coated implantable medical device comprising paclitaxel
DE19855421C2 (de) * 1998-11-02 2001-09-20 Alcove Surfaces Gmbh Implantat
US6274294B1 (en) * 1999-02-03 2001-08-14 Electroformed Stents, Inc. Cylindrical photolithography exposure process and apparatus
US6368658B1 (en) * 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6607598B2 (en) 1999-04-19 2003-08-19 Scimed Life Systems, Inc. Device for protecting medical devices during a coating process
US6368346B1 (en) * 1999-06-03 2002-04-09 American Medical Systems, Inc. Bioresorbable stent
US6258121B1 (en) * 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
IL147803A0 (en) 1999-08-24 2002-08-14 Ariad Gene Therapeutics Inc 28-epirapalogs
US6713119B2 (en) 1999-09-03 2004-03-30 Advanced Cardiovascular Systems, Inc. Biocompatible coating for a prosthesis and a method of forming the same
US6790228B2 (en) 1999-12-23 2004-09-14 Advanced Cardiovascular Systems, Inc. Coating for implantable devices and a method of forming the same
US6379381B1 (en) * 1999-09-03 2002-04-30 Advanced Cardiovascular Systems, Inc. Porous prosthesis and a method of depositing substances into the pores
IL133312A (en) * 1999-12-05 2006-09-05 Orbotech Ltd Method for testing a printed circuit
AU2001230956B2 (en) * 2000-01-14 2005-08-18 The Trustees Of The University Of Pennsylvania O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders
US6312463B1 (en) * 2000-02-01 2001-11-06 Endotex Interventional Systems, Inc. Micro-porous mesh stent with hybrid structure
US20050271701A1 (en) 2000-03-15 2005-12-08 Orbus Medical Technologies, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
AU2001261465A1 (en) * 2000-05-12 2001-11-26 The Regents Of The University Of Michigan Reverse fabrication of porous materials
US6585151B1 (en) * 2000-05-23 2003-07-01 The Regents Of The University Of Michigan Method for producing microporous objects with fiber, wire or foil core and microporous cellular objects
DE10037850A1 (de) * 2000-08-01 2002-02-21 Herbert P Jennissen Verfahren zur Herstellung bioaktiver Implantatoberflächen
WO2002026162A2 (en) 2000-09-26 2002-04-04 Advanced Cardiovascular Systems, Inc. A method of loading a substance onto an implantable device
US6805898B1 (en) 2000-09-28 2004-10-19 Advanced Cardiovascular Systems, Inc. Surface features of an implantable medical device
AU1129902A (en) 2000-09-29 2002-04-08 Cordis Corp Coated medical devices
US6746773B2 (en) * 2000-09-29 2004-06-08 Ethicon, Inc. Coatings for medical devices
US20020051730A1 (en) * 2000-09-29 2002-05-02 Stanko Bodnar Coated medical devices and sterilization thereof
US20020111590A1 (en) * 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
EP1582180B1 (en) 2000-10-16 2008-02-27 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US7803149B2 (en) * 2002-07-12 2010-09-28 Cook Incorporated Coated medical device
US7083642B2 (en) * 2000-12-22 2006-08-01 Avantec Vascular Corporation Delivery of therapeutic capable agents
US20030033007A1 (en) * 2000-12-22 2003-02-13 Avantec Vascular Corporation Methods and devices for delivery of therapeutic capable agents with variable release profile
US20020082679A1 (en) * 2000-12-22 2002-06-27 Avantec Vascular Corporation Delivery or therapeutic capable agents
US7077859B2 (en) * 2000-12-22 2006-07-18 Avantec Vascular Corporation Apparatus and methods for variably controlled substance delivery from implanted prostheses
WO2002056790A2 (en) 2000-12-22 2002-07-25 Avantec Vascular Corporation Delivery of therapeutic capable agents
US20030050692A1 (en) * 2000-12-22 2003-03-13 Avantec Vascular Corporation Delivery of therapeutic capable agents
US6913617B1 (en) * 2000-12-27 2005-07-05 Advanced Cardiovascular Systems, Inc. Method for creating a textured surface on an implantable medical device
CN1360951A (zh) * 2000-12-28 2002-07-31 微创医疗器械(上海)有限公司 一种具有防再狭窄涂层的血管支架
US6544582B1 (en) * 2001-01-05 2003-04-08 Advanced Cardiovascular Systems, Inc. Method and apparatus for coating an implantable device
US6540777B2 (en) * 2001-02-15 2003-04-01 Scimed Life Systems, Inc. Locking stent
US20060051868A1 (en) * 2001-02-22 2006-03-09 Pullman Gerald S Methods for increasing conifer somatic embryo initiation, capture, and multiplication
US7128755B2 (en) 2001-06-01 2006-10-31 Texas Stent Technologies, Inc. Expandable biodegradable polymeric stents for combined mechanical support and pharmacological or radiation therapy
TW514350U (en) * 2001-06-22 2002-12-11 Coretronic Corp Projecting device with heat-dissipating fan
US20030050687A1 (en) * 2001-07-03 2003-03-13 Schwade Nathan D. Biocompatible stents and method of deployment
US6641611B2 (en) 2001-11-26 2003-11-04 Swaminathan Jayaraman Therapeutic coating for an intravascular implant
US6908622B2 (en) * 2001-09-24 2005-06-21 Boston Scientific Scimed, Inc. Optimized dosing for drug coated stents
US20030077310A1 (en) * 2001-10-22 2003-04-24 Chandrashekhar Pathak Stent coatings containing HMG-CoA reductase inhibitors
US7682387B2 (en) * 2002-04-24 2010-03-23 Biosensors International Group, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US6743463B2 (en) * 2002-03-28 2004-06-01 Scimed Life Systems, Inc. Method for spray-coating a medical device having a tubular wall such as a stent
US20040024450A1 (en) * 2002-04-24 2004-02-05 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US20040024448A1 (en) * 2002-08-05 2004-02-05 Chang James W. Thermoplastic fluoropolymer-coated medical devices
US6911100B1 (en) * 2002-08-30 2005-06-28 Biomet, Inc. Method for controlling residual stress in prosthetics
ATE392864T1 (de) * 2002-09-20 2008-05-15 Abbott Lab Vascular Entpr Ltd Mit einer rauhen oberfläche versehener stent und sein herstellungsverfahren
CN1725988A (zh) 2002-11-13 2006-01-25 斯特根有限公司 具有多孔层的医用装置及其制造方法
US20060002968A1 (en) * 2004-06-30 2006-01-05 Gordon Stewart Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders
CN1223385C (zh) * 2002-12-31 2005-10-19 中国科学院金属研究所 一种具有控制释放治疗性药物的心血管支架
US6919100B2 (en) * 2003-01-22 2005-07-19 Cordis Corporation Method for coating medical devices
US20040249442A1 (en) 2003-02-26 2004-12-09 Fleming James A. Locking stent having multiple locking points
US6904658B2 (en) * 2003-06-02 2005-06-14 Electroformed Stents, Inc. Process for forming a porous drug delivery layer
US7055237B2 (en) * 2003-09-29 2006-06-06 Medtronic Vascular, Inc. Method of forming a drug eluting stent
US7220755B2 (en) * 2003-11-12 2007-05-22 Biosensors International Group, Ltd. 42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
EP1778761B1 (en) * 2004-08-13 2021-09-29 Reva Medical, Inc. Inherently radiopaque bioresorbable polymers for multiple uses
KR20070063511A (ko) 2004-08-13 2007-06-19 세타곤 인코포레이티드 나노 다공성 층을 구비하는 의료 장치 및 그 제조 방법
US7901451B2 (en) 2004-09-24 2011-03-08 Biosensors International Group, Ltd. Drug-delivery endovascular stent and method for treating restenosis
AU2006231652A1 (en) 2005-04-05 2006-10-12 Elixir Medical Corporation Degradable implantable medical devices
WO2008011614A2 (en) * 2006-07-20 2008-01-24 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
US8460362B2 (en) * 2006-07-20 2013-06-11 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
US7959942B2 (en) * 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020098278A1 (en) * 2000-10-31 2002-07-25 Cook Incorporated Coated implantable medical device
WO2003022807A2 (en) * 2001-09-10 2003-03-20 Abbott Laboratories Medical devices containing rapamycin analogs
WO2003090818A2 (en) * 2002-04-24 2003-11-06 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis

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