AU2005287160C1 - Antisense antiviral compound and method for treating ssRNA viral infection - Google Patents

Antisense antiviral compound and method for treating ssRNA viral infection Download PDF

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Publication number
AU2005287160C1
AU2005287160C1 AU2005287160A AU2005287160A AU2005287160C1 AU 2005287160 C1 AU2005287160 C1 AU 2005287160C1 AU 2005287160 A AU2005287160 A AU 2005287160A AU 2005287160 A AU2005287160 A AU 2005287160A AU 2005287160 C1 AU2005287160 C1 AU 2005287160C1
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virus
compound
seq
rna
sequence
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AU2005287160B2 (en
AU2005287160A1 (en
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Patrick L. Iversen
David A. Stein
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Sarepta Therapeutics Inc
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Sarepta Therapeutics Inc
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Assigned to SAREPTA THERAPEUTICS, INC. reassignment SAREPTA THERAPEUTICS, INC. Amend patent request/document other than specification (104) Assignors: AVI BIOPHARMA, INC.
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    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/11—Antisense
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C12N2310/323—Chemical structure of the sugar modified ring structure
    • C12N2310/3233—Morpholino-type ring
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    • C12N2770/00011—Details
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    • C12N2770/12011—Astroviridae
    • C—CHEMISTRY; METALLURGY
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    • C12N2770/00011—Details
    • C12N2770/16011—Caliciviridae
    • C—CHEMISTRY; METALLURGY
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    • C12N2770/20011—Coronaviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/24011—Flaviviridae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2770/00011—Details
    • C12N2770/28011—Hepeviridae
    • C—CHEMISTRY; METALLURGY
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    • C12N2770/32011—Picornaviridae
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    • C12N2770/00011—Details
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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AU2005287160A 2004-09-16 2005-09-15 Antisense antiviral compound and method for treating ssRNA viral infection Ceased AU2005287160C1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61106304P 2004-09-16 2004-09-16
US60/611,063 2004-09-16
US11/226,995 2005-09-14
US11/226,995 US8129352B2 (en) 2004-09-16 2005-09-14 Antisense antiviral compound and method for treating ssRNA viral infection
PCT/US2005/032815 WO2006033933A2 (en) 2004-09-16 2005-09-15 Antisense antiviral compound and method for treating ssrna viral infection

Publications (3)

Publication Number Publication Date
AU2005287160A1 AU2005287160A1 (en) 2006-03-30
AU2005287160B2 AU2005287160B2 (en) 2012-06-28
AU2005287160C1 true AU2005287160C1 (en) 2012-12-13

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AU2005287160A Ceased AU2005287160C1 (en) 2004-09-16 2005-09-15 Antisense antiviral compound and method for treating ssRNA viral infection

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US (4) US8129352B2 (https=)
EP (1) EP1802777B1 (https=)
JP (1) JP5425396B2 (https=)
AU (1) AU2005287160C1 (https=)
CA (1) CA2579815C (https=)
WO (1) WO2006033933A2 (https=)

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