AU2005210326B2 - Drug for inhibiting vascular intimal hyperplasia - Google Patents

Drug for inhibiting vascular intimal hyperplasia Download PDF

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Publication number
AU2005210326B2
AU2005210326B2 AU2005210326A AU2005210326A AU2005210326B2 AU 2005210326 B2 AU2005210326 B2 AU 2005210326B2 AU 2005210326 A AU2005210326 A AU 2005210326A AU 2005210326 A AU2005210326 A AU 2005210326A AU 2005210326 B2 AU2005210326 B2 AU 2005210326B2
Authority
AU
Australia
Prior art keywords
hydrogen atom
pyridazinone
intimal hyperplasia
pharmacologically acceptable
halogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005210326A
Other languages
English (en)
Other versions
AU2005210326A1 (en
Inventor
Hiroshi Nishiyama
Norimasa Shudo
Nobutomo Tsuruzoe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp, Taisho Pharmaceutical Co Ltd filed Critical Nissan Chemical Corp
Publication of AU2005210326A1 publication Critical patent/AU2005210326A1/en
Application granted granted Critical
Publication of AU2005210326B2 publication Critical patent/AU2005210326B2/en
Assigned to NISSAN CHEMICAL INDUSTRIES, LTD. reassignment NISSAN CHEMICAL INDUSTRIES, LTD. Request for Assignment Assignors: NISSAN CHEMICAL INDUSTRIES, LTD., TAISHO PHARMACEUTICAL CO., LTD.
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU2005210326A 2004-02-09 2005-02-02 Drug for inhibiting vascular intimal hyperplasia Ceased AU2005210326B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004032551 2004-02-09
JP2004-032551 2004-02-09
PCT/JP2005/001518 WO2005074938A1 (ja) 2004-02-09 2005-02-02 血管内膜肥厚抑制薬

Publications (2)

Publication Number Publication Date
AU2005210326A1 AU2005210326A1 (en) 2005-08-18
AU2005210326B2 true AU2005210326B2 (en) 2009-10-22

Family

ID=34836093

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2005210326A Ceased AU2005210326B2 (en) 2004-02-09 2005-02-02 Drug for inhibiting vascular intimal hyperplasia

Country Status (13)

Country Link
US (2) US20070161642A1 (ru)
EP (1) EP1714654A4 (ru)
JP (1) JP4783152B2 (ru)
KR (1) KR20070029133A (ru)
CN (1) CN100506230C (ru)
AU (1) AU2005210326B2 (ru)
BR (1) BRPI0507518A8 (ru)
CA (1) CA2553915C (ru)
HK (1) HK1098377A1 (ru)
IL (1) IL176795A (ru)
RU (1) RU2339381C2 (ru)
TW (1) TWI357409B (ru)
WO (1) WO2005074938A1 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7723362B2 (en) * 2004-01-08 2010-05-25 Syngenta Crop Protection, Inc. Pesticidal heterocyclic dihaloallyl compounds
EP1604988A1 (en) * 2004-05-18 2005-12-14 Sanofi-Aventis Deutschland GmbH Pyridazinone derivatives, methods for producing them and their use as pharmaceuticals
MX2009008531A (es) * 2007-02-16 2009-08-26 Amgen Inc Cetonas de heterociclilo que contienen nitrogeno y su uso como inhibidores de c-met.
FR2948939B1 (fr) * 2009-08-05 2013-03-22 Pf Medicament Derives de 2h pyridazin-3-ones, leur preparation et leur application en therapeutique humaine

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0482208A1 (en) * 1990-04-25 1992-04-29 Nissan Chemical Industries Ltd. Pyridazinone derivative
US5856327A (en) * 1994-01-25 1999-01-05 Nissan Chemical Industries, Ltd. Pyridazinone derivatives
EP1157694A1 (en) * 1998-12-07 2001-11-28 Nissan Chemical Industries, Ltd. Remedial agent for erectile dysfunction

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3666042B2 (ja) * 1994-01-25 2005-06-29 日産化学工業株式会社 ピリダジノン誘導体
TW338037B (en) * 1995-10-05 1998-08-11 Otsuka Pharma Co Ltd Carbostyril derivatives possessing platelet aggregation inhibitory activity, antithrombotic activity, intima thinkening, inhibitory activity and phosphoriesterase inhibitory activity, their preparation and pharmaceutical composition
JP2964029B2 (ja) * 1995-10-05 1999-10-18 大塚製薬株式会社 カルボスチリル誘導体
US6284758B1 (en) * 1997-08-28 2001-09-04 Welfide Corporation Angiogenesis promoters and angiogenesis potentiators
JP4366865B2 (ja) * 1998-09-01 2009-11-18 日産化学工業株式会社 脊柱管狭窄症治療剤
JP2001131088A (ja) * 1999-11-02 2001-05-15 Kyurin:Kk シンドロームｘ症候群治療剤
CA2304906A1 (en) * 2000-04-07 2001-10-07 1411198 Ontario Limited 13-hode, a regulator of vascular biocompatibility and an inhibitor of cell hyperplasia

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0482208A1 (en) * 1990-04-25 1992-04-29 Nissan Chemical Industries Ltd. Pyridazinone derivative
US5856327A (en) * 1994-01-25 1999-01-05 Nissan Chemical Industries, Ltd. Pyridazinone derivatives
EP1157694A1 (en) * 1998-12-07 2001-11-28 Nissan Chemical Industries, Ltd. Remedial agent for erectile dysfunction

Also Published As

Publication number Publication date
RU2006132389A (ru) 2008-03-20
EP1714654A4 (en) 2011-02-16
BRPI0507518A8 (pt) 2015-12-01
TWI357409B (en) 2012-02-01
KR20070029133A (ko) 2007-03-13
EP1714654A1 (en) 2006-10-25
HK1098377A1 (en) 2007-07-20
JP4783152B2 (ja) 2011-09-28
IL176795A (en) 2013-01-31
JPWO2005074938A1 (ja) 2007-09-13
US20090155187A1 (en) 2009-06-18
BRPI0507518A (pt) 2007-07-03
TW200530218A (en) 2005-09-16
IL176795A0 (en) 2006-10-31
CA2553915C (en) 2010-06-01
CA2553915A1 (en) 2005-08-18
CN1905882A (zh) 2007-01-31
US20070161642A1 (en) 2007-07-12
AU2005210326A1 (en) 2005-08-18
WO2005074938A1 (ja) 2005-08-18
CN100506230C (zh) 2009-07-01
RU2339381C2 (ru) 2008-11-27

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: NISSAN CHEMICAL INDUSTRIES, LTD.

Free format text: FORMER OWNER WAS: NISSAN CHEMICAL INDUSTRIES, LTD.; TAISHO PHARMACEUTICAL CO., LTD.

MK14 Patent ceased section 143(a) (annual fees not paid) or expired