AU2004278425A1 - Mammalian T1R3 sweet taste receptors - Google Patents
Mammalian T1R3 sweet taste receptors Download PDFInfo
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- AU2004278425A1 AU2004278425A1 AU2004278425A AU2004278425A AU2004278425A1 AU 2004278425 A1 AU2004278425 A1 AU 2004278425A1 AU 2004278425 A AU2004278425 A AU 2004278425A AU 2004278425 A AU2004278425 A AU 2004278425A AU 2004278425 A1 AU2004278425 A1 AU 2004278425A1
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- 230000009967 tasteless effect Effects 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 208000002918 testicular germ cell tumor Diseases 0.000 description 1
- 101150024821 tetO gene Proteins 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- MPLHNVLQVRSVEE-UHFFFAOYSA-N texas red Chemical compound [O-]S(=O)(=O)C1=CC(S(Cl)(=O)=O)=CC=C1C(C1=CC=2CCCN3CCCC(C=23)=C1O1)=C2C1=C(CCC1)C3=[N+]1CCCC3=C2 MPLHNVLQVRSVEE-UHFFFAOYSA-N 0.000 description 1
- 210000001103 thalamus Anatomy 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 150000003568 thioethers Chemical class 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 239000005495 thyroid hormone Substances 0.000 description 1
- 229940036555 thyroid hormone Drugs 0.000 description 1
- 230000001550 time effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 238000003151 transfection method Methods 0.000 description 1
- 239000012581 transferrin Substances 0.000 description 1
- 238000003146 transient transfection Methods 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- 230000014621 translational initiation Effects 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- ORHBXUUXSCNDEV-UHFFFAOYSA-N umbelliferone Chemical compound C1=CC(=O)OC2=CC(O)=CC=C21 ORHBXUUXSCNDEV-UHFFFAOYSA-N 0.000 description 1
- HFTAFOQKODTIJY-UHFFFAOYSA-N umbelliferone Natural products Cc1cc2C=CC(=O)Oc2cc1OCC=CC(C)(C)O HFTAFOQKODTIJY-UHFFFAOYSA-N 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
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- 239000002435 venom Substances 0.000 description 1
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- 231100000611 venom Toxicity 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 235000019166 vitamin D Nutrition 0.000 description 1
- 239000011710 vitamin D Substances 0.000 description 1
- 150000003710 vitamin D derivatives Chemical class 0.000 description 1
- 229940046008 vitamin d Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/679,102 US20050106571A1 (en) | 2003-10-02 | 2003-10-02 | Mammalian T1R3 sweet taste receptors |
| US10/679,102 | 2003-10-02 | ||
| PCT/US2004/032678 WO2005033125A2 (en) | 2003-10-02 | 2004-10-04 | Mammalian t1r3 sweet taste receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2004278425A1 true AU2004278425A1 (en) | 2005-04-14 |
Family
ID=34422153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2004278425A Abandoned AU2004278425A1 (en) | 2003-10-02 | 2004-10-04 | Mammalian T1R3 sweet taste receptors |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20050106571A1 (https=) |
| EP (1) | EP1684789A4 (https=) |
| JP (1) | JP2007507544A (https=) |
| AU (1) | AU2004278425A1 (https=) |
| CA (1) | CA2540837A1 (https=) |
| WO (1) | WO2005033125A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973155A (zh) * | 2020-08-23 | 2020-11-24 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201006846A (en) * | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| CA2408140A1 (en) * | 2000-05-22 | 2001-11-29 | Incyte Genomics, Inc. | G-protein coupled receptors |
| TW201022287A (en) * | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7309577B2 (en) * | 2001-03-07 | 2007-12-18 | Senomyx, Inc. | Binding assays that use the T1R1/T1R3 (umami) taste receptor to identify compounds that elicit or modulate umami taste |
| US7368285B2 (en) * | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US7301009B2 (en) * | 2001-06-26 | 2007-11-27 | Senomyx, Inc. | Isolated (T1R1/T1R3) umami taste receptors that respond to umami taste stimuli |
| US20080244761A1 (en) | 2001-03-07 | 2008-10-02 | Senomyx, Inc. | T1r hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| US7763431B1 (en) | 2001-03-07 | 2010-07-27 | Senomyx, Inc. | Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste |
| DK2327985T3 (en) | 2001-06-26 | 2016-09-05 | Senomyx Inc | H1 Oligomeric T1R Taste Receptors and Cell Lines Expressing the Receptors, and Their Use to Identify Taste Compounds |
| US8796441B2 (en) | 2005-04-13 | 2014-08-05 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Human sweet and umami taste receptor variants |
| US9101160B2 (en) | 2005-11-23 | 2015-08-11 | The Coca-Cola Company | Condiments with high-potency sweetener |
| DK1865316T3 (da) | 2006-06-07 | 2010-05-25 | Nutrinova Gmbh | Fremgangsmåde til screening af forbindelser, der modulerer aktiviteten af G-protein-koblede receptorer |
| US20080026416A1 (en) * | 2006-07-27 | 2008-01-31 | Harish Radhakrishna | Model Taste Cells and Methods of Use for Identifying Modulators of Taste Sensation |
| EP2560001B1 (en) * | 2006-09-21 | 2016-04-13 | University of Rochester | Compositions and methods related to protein displacement therapy for myotonic distrophy |
| US8017168B2 (en) | 2006-11-02 | 2011-09-13 | The Coca-Cola Company | High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith |
| US20100311610A1 (en) * | 2008-02-01 | 2010-12-09 | Chromocell Corporation | CELL LINES AND METHODS FOR MAKING AND USING THEM (As Amended) |
| ES2637411T3 (es) | 2008-12-01 | 2017-10-13 | Laboratory Corporation Of America Holdings | Métodos y ensayos para medir p95 Y/O p95 en una muestra y anticuerpos específicos para p95 |
| JP2012515353A (ja) * | 2009-01-15 | 2012-07-05 | ラボラトリー コーポレイション オブ アメリカ ホールディングス | Ｈｅｒ−２発現の測定による患者の反応を判定する方法 |
| EP2387711B1 (en) | 2009-01-15 | 2015-04-22 | Laboratory Corporation of America Holdings | Methods of determining patient response by measurement of her-3 |
| US9128079B2 (en) | 2011-08-08 | 2015-09-08 | The Coca-Cola Company | Methods of using lung or bronchial epithelial cells to identify bitter taste modulators |
| US9804157B1 (en) | 2013-03-15 | 2017-10-31 | Senomyx, Inc. | Screening assays to identify compounds which modulate T1R associated taste modalities which eliminate false positives |
| WO2014183041A1 (en) | 2013-05-10 | 2014-11-13 | Pepsico, Inc. | Taste receptor internalization assay |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7402400B2 (en) * | 2001-07-03 | 2008-07-22 | Regents Of The University Of California | Mammalian sweet taste receptors |
| DK1100811T3 (da) | 1998-07-28 | 2007-11-05 | Univ California | Nucleinsyrer, som koder for en G-protein-koblet receptor involveret i sensorisk transduktion |
| WO2001064882A2 (en) | 2000-02-29 | 2001-09-07 | Millennium Pharmaceuticals, Inc. | 1983, 52881, 2398, 45449, 50289, and 52872, g protein-coupled receptors and uses therefor |
| TW201006846A (en) | 2000-03-07 | 2010-02-16 | Senomyx Inc | T1R taste receptor and genes encidung same |
| CA2406999A1 (en) | 2000-04-28 | 2001-11-08 | Warner-Lambert Company | Gene and sequence variation associated with sensing carbohydrate compounds and other sweeteners |
| TW201022287A (en) | 2001-01-03 | 2010-06-16 | Senomyx Inc | T1R taste receptors and genes encoding same |
| US7368285B2 (en) | 2001-03-07 | 2008-05-06 | Senomyx, Inc. | Heteromeric umami T1R1/T1R3 taste receptors and isolated cells that express same |
| US6955887B2 (en) * | 2001-03-30 | 2005-10-18 | Senomyx, Inc. | Use of T1R hetero-oligomeric taste receptor to screen for compounds that modulate taste signaling |
| EP1572871A4 (en) * | 2001-04-20 | 2007-11-14 | Sinai School Medicine | T1R3, A NEW TASTE RECEPTOR |
| JP3698069B2 (ja) * | 2001-05-01 | 2005-09-21 | 独立行政法人食品総合研究所 | 新規遺伝子 |
| US20030143668A1 (en) | 2001-06-18 | 2003-07-31 | National Institute Of Advanced Industrial | Guanosine triphosphate-binding protein coupled receptors |
| EP2293067B1 (en) | 2001-06-26 | 2016-04-20 | Senomyx, Inc. | T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds |
| AU2002336571A1 (en) | 2001-09-18 | 2003-04-01 | Irm, Llc | Sweet taste receptors |
-
2003
- 2003-10-02 US US10/679,102 patent/US20050106571A1/en not_active Abandoned
-
2004
- 2004-10-04 CA CA002540837A patent/CA2540837A1/en not_active Abandoned
- 2004-10-04 WO PCT/US2004/032678 patent/WO2005033125A2/en not_active Ceased
- 2004-10-04 AU AU2004278425A patent/AU2004278425A1/en not_active Abandoned
- 2004-10-04 JP JP2006534237A patent/JP2007507544A/ja active Pending
- 2004-10-04 EP EP04794142A patent/EP1684789A4/en not_active Ceased
-
2006
- 2006-04-10 US US11/402,202 patent/US7459277B2/en not_active Expired - Lifetime
-
2008
- 2008-10-23 US US12/257,290 patent/US7939279B2/en not_active Expired - Lifetime
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111973155A (zh) * | 2020-08-23 | 2020-11-24 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
| CN111973155B (zh) * | 2020-08-23 | 2023-06-16 | 吾征智能技术(北京)有限公司 | 一种基于人体口味异常变化的疾病认知自学习系统 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090155819A1 (en) | 2009-06-18 |
| US20070105159A1 (en) | 2007-05-10 |
| US20050106571A1 (en) | 2005-05-19 |
| EP1684789A4 (en) | 2006-12-27 |
| US7459277B2 (en) | 2008-12-02 |
| EP1684789A2 (en) | 2006-08-02 |
| WO2005033125A2 (en) | 2005-04-14 |
| JP2007507544A (ja) | 2007-03-29 |
| US7939279B2 (en) | 2011-05-10 |
| CA2540837A1 (en) | 2005-04-14 |
| WO2005033125A3 (en) | 2006-03-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK4 | Application lapsed section 142(2)(d) - no continuation fee paid for the application |