AU2004231122B2 - Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof - Google Patents
Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof Download PDFInfo
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- AU2004231122B2 AU2004231122B2 AU2004231122A AU2004231122A AU2004231122B2 AU 2004231122 B2 AU2004231122 B2 AU 2004231122B2 AU 2004231122 A AU2004231122 A AU 2004231122A AU 2004231122 A AU2004231122 A AU 2004231122A AU 2004231122 B2 AU2004231122 B2 AU 2004231122B2
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
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- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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Priority Applications (1)
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| AU2010202722A AU2010202722B2 (en) | 2003-04-15 | 2010-06-29 | Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof |
Applications Claiming Priority (7)
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| US46286703P | 2003-04-15 | 2003-04-15 | |
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| US60/488,607 | 2003-07-18 | ||
| US49845803P | 2003-08-28 | 2003-08-28 | |
| US60/498,458 | 2003-08-28 | ||
| PCT/CA2004/000522 WO2004092405A2 (en) | 2003-04-15 | 2004-04-08 | Juvenile hemochromatosis gene (hfe2a), expression products and uses thereof |
Related Child Applications (1)
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| AU2010202722A Division AU2010202722B2 (en) | 2003-04-15 | 2010-06-29 | Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof |
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| AU2004231122B2 true AU2004231122B2 (en) | 2010-04-08 |
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| AU2010202722A Ceased AU2010202722B2 (en) | 2003-04-15 | 2010-06-29 | Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof |
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| AU2010202722A Ceased AU2010202722B2 (en) | 2003-04-15 | 2010-06-29 | Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof |
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| EP (2) | EP2006298A3 (https=) |
| JP (1) | JP2006523440A (https=) |
| AU (2) | AU2004231122B2 (https=) |
| CA (1) | CA2522680A1 (https=) |
| WO (1) | WO2004092405A2 (https=) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7981420B2 (en) | 2000-12-22 | 2011-07-19 | Max-Planck-Gesellschaft Zur Foederung Der Wissenschaften E.V. | Therapeutic use of antibodies directed against repulsive guidance molecule (RGM) |
| WO2003089608A2 (en) | 2002-04-18 | 2003-10-30 | The General Hospital Corporation | Drg11-responsive (dragon) gene family |
| AU2004231122B2 (en) | 2003-04-15 | 2010-04-08 | Xenon Pharmaceuticals Inc. | Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof |
| US8101816B2 (en) * | 2004-07-23 | 2012-01-24 | Novartis Forschungsstiftung, Zweigniederalassung Friedrich Miescher Institute for Biomedical Research | RGMc modified transgenic animals |
| WO2006088972A2 (en) * | 2005-02-16 | 2006-08-24 | The General Hospital Corporation | Use of modulatirs of compounds of tgf-beta superfamily to regulate hepcidin-mediated iron metabolism |
| CA2549477A1 (en) * | 2005-06-29 | 2006-12-29 | The Regents Of The University Of California | Competitive regulation of hepcidin mrna by soluble and cell-associated hemojuvelin |
| EP1928905B1 (de) * | 2005-09-30 | 2015-04-15 | AbbVie Deutschland GmbH & Co KG | Bindungsdomänen von proteinen der repulsive guidance molecule (rgm) proteinfamilie und funktionale fragmente davon sowie deren verwendung |
| WO2008079877A2 (en) * | 2006-12-22 | 2008-07-03 | Xenon Pharmaceuticals Inc. | Compositions and methods for the diagnosis and treatment of iron-related disorders |
| TW201307390A (zh) * | 2007-02-02 | 2013-02-16 | Amgen Inc | 海帕西啶（ｈｅｐｃｉｄｉｎ）、海帕西啶拮抗劑及使用方法 |
| WO2008124768A1 (en) | 2007-04-09 | 2008-10-16 | The General Hospital Corporation | Hemojuvelin fusion proteins and uses thereof |
| EP2033971A1 (de) * | 2007-09-06 | 2009-03-11 | Abbott GmbH & Co. KG | Bone Morphogenetic Protein (BMP)-bindende Domänen von Proteinen der Repulsive Guidance Molecule (RGM) Proteinfamilie und funktionale Fragmente davon sowie deren Verwendung |
| MX2010003371A (es) | 2007-09-28 | 2010-05-05 | Intrexon Corp | Constructos interruptores genicos terapeuticos y biorreactores para la expresion de moleculas bioterapeuticas y usos de los mismos. |
| US8962803B2 (en) | 2008-02-29 | 2015-02-24 | AbbVie Deutschland GmbH & Co. KG | Antibodies against the RGM A protein and uses thereof |
| US20100068737A1 (en) * | 2008-09-16 | 2010-03-18 | University Of Tennessee Research Foundation | Enzyme-linked Immunosorbent Assay (ELISA) for Canine Hepcidin |
| US8435941B2 (en) | 2008-12-05 | 2013-05-07 | The Regents Of The University Of California | Mini-hepcidin peptides and methods of using thereof |
| KR101722961B1 (ko) | 2009-02-11 | 2017-04-04 | 알부메딕스 에이/에스 | 알부민 변이체 및 접합체 |
| EP2493921B1 (en) | 2009-10-30 | 2018-09-26 | Albumedix Ltd | Albumin variants |
| MX2012006560A (es) | 2009-12-08 | 2012-10-05 | Abbott Gmbh & Co Kg | Anticuerpos monoclonales contra la proteina rgm a para utilizarse en el tratamiento de degeneracion de capa de fibra de nervio retinal. |
| EP2556087A1 (en) | 2010-04-09 | 2013-02-13 | Novozymes Biopharma DK A/S | Albumin derivatives and variants |
| AU2012251919B2 (en) | 2011-01-19 | 2016-12-15 | Ferrumax Pharmaceuticals, Inc. | Compositions for regulating iron homeostasis and methods of using same |
| EP2780364A2 (en) | 2011-11-18 | 2014-09-24 | Eleven Biotherapeutics, Inc. | Proteins with improved half-life and other properties |
| BR112014013697A2 (pt) | 2011-12-09 | 2020-11-03 | The Regents Of The University Of California | peptídeos mini-hepcidina modificados e métodos de uso dos mesmos |
| EP3369746A1 (en) | 2012-01-27 | 2018-09-05 | AbbVie Deutschland GmbH & Co KG | Composition and method for diagnosis and treatment of diseases associated with neurite degeneration |
| DK2825556T3 (en) | 2012-03-16 | 2018-04-16 | Albumedix As | albumin Variants |
| MX2015005363A (es) | 2012-11-08 | 2015-11-06 | Novozymes Biopharma Dk As | Variantes de albumina. |
| EP4091624A1 (en) | 2013-03-15 | 2022-11-23 | Protagonist Therapeutics, Inc. | Hepcidin analogues and uses thereof |
| HRP20211448T1 (hr) | 2014-05-16 | 2021-12-24 | Protagonist Therapeutics, Inc. | Alfa4beta7 integrin tioeter peptidni antagonisti |
| CN107206254B (zh) | 2014-07-17 | 2021-08-24 | 领导医疗有限公司 | 白细胞介素-23受体的口服肽抑制剂以及其治疗炎症性肠病的用途 |
| US10301371B2 (en) | 2014-10-01 | 2019-05-28 | Protagonist Therapeutics, Inc. | Cyclic monomer and dimer peptides having integrin antagonist activity |
| WO2016054411A1 (en) | 2014-10-01 | 2016-04-07 | Protagonist Therapeutics, Inc. | NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS |
| EP3240799B1 (en) | 2014-12-29 | 2021-03-31 | The Regents of the University of California | S-alkylated hepcidin peptides and methods of making and using thereof |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP7007261B2 (ja) | 2015-08-20 | 2022-01-24 | アルブミディクス リミティド | アルブミン変異体及びコンジュゲート |
| US20190002503A1 (en) | 2015-12-30 | 2019-01-03 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| CA3017926C (en) | 2016-03-23 | 2023-10-10 | Protagonist Therapeutics, Inc. | Methods for synthesizing .alpha.4.beta.7 peptide antagonists |
| WO2018128828A1 (en) | 2016-12-23 | 2018-07-12 | Bayer Healthcare Llc | Novel hepcidin mimetics and uses thereof |
| EP3681900A4 (en) | 2017-09-11 | 2021-09-08 | Protagonist Therapeutics, Inc. | OPIOID AGONIST PEPTIDES AND THEIR USES |
| CA3089868A1 (en) | 2018-02-08 | 2019-08-15 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| CA3045370A1 (en) | 2018-06-08 | 2019-12-08 | Pfizer Inc. | Methods of treating metabolic disease |
| WO2020014646A1 (en) | 2018-07-12 | 2020-01-16 | Protagonist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| JP7534382B2 (ja) | 2019-07-10 | 2024-08-14 | プロタゴニスト セラピューティクス， インコーポレイテッド | インターロイキン－２３受容体のペプチド阻害剤及び炎症性疾患を治療するためのその使用 |
| US20220372135A1 (en) | 2019-09-27 | 2022-11-24 | Disc Medicine, Inc. | Methods for treating myelofibrosis and related conditions |
| CA3167751A1 (en) | 2020-01-15 | 2021-07-22 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| AU2021209086A1 (en) | 2020-01-15 | 2022-08-04 | Janssen Biotech, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| KR20230012539A (ko) | 2020-05-13 | 2023-01-26 | 디스크 메디슨, 인크. | 골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체 |
| JP7397239B2 (ja) | 2020-11-20 | 2023-12-12 | ヤンセン ファーマシューティカ エヌ．ベー． | インターロイキン－２３受容体のペプチド阻害剤の組成物 |
| EP4370146A4 (en) | 2021-07-14 | 2025-05-21 | Janssen Biotech, Inc. | Lipidated peptide inhibitors of the interleukin-23 receptor |
| JP2024540480A (ja) | 2021-11-17 | 2024-10-31 | ディスク・メディシン・インコーポレイテッド | 腎臓疾患の貧血を処置する方法 |
| JP2026506602A (ja) | 2023-02-13 | 2026-02-25 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 鉄過剰関連疾患の処置方法 |
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| US5994315A (en) * | 1995-06-07 | 1999-11-30 | East Carolina University | Low adenosine agent, composition, kit and method for treatment of airway disease |
| US6319906B1 (en) * | 1996-12-31 | 2001-11-20 | Isis Pharmaceuticals | Oligonucleotide compositions and methods for the modulation of the expression of B7 protein |
| US5877309A (en) * | 1997-08-13 | 1999-03-02 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotides against JNK |
| WO2000073801A2 (en) | 1999-05-28 | 2000-12-07 | Ludwig Institute For Cancer Research | Breast, gastric and prostate cancer associated antigens and uses therefor |
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| CA2549477A1 (en) * | 2005-06-29 | 2006-12-29 | The Regents Of The University Of California | Competitive regulation of hepcidin mrna by soluble and cell-associated hemojuvelin |
-
2004
- 2004-04-08 AU AU2004231122A patent/AU2004231122B2/en not_active Ceased
- 2004-04-08 EP EP08154618A patent/EP2006298A3/en not_active Withdrawn
- 2004-04-08 WO PCT/CA2004/000522 patent/WO2004092405A2/en not_active Ceased
- 2004-04-08 JP JP2006504100A patent/JP2006523440A/ja active Pending
- 2004-04-08 CA CA002522680A patent/CA2522680A1/en not_active Abandoned
- 2004-04-08 US US10/552,158 patent/US20070166711A1/en not_active Abandoned
- 2004-04-08 EP EP04726398A patent/EP1618131A2/en not_active Withdrawn
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2005
- 2005-08-04 US US11/197,710 patent/US7511018B2/en not_active Expired - Fee Related
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2009
- 2009-02-09 US US12/322,931 patent/US7893206B2/en not_active Expired - Fee Related
- 2009-06-19 US US12/456,667 patent/US8080651B2/en not_active Expired - Fee Related
- 2009-09-15 US US12/584,947 patent/US20100068803A1/en not_active Abandoned
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2010
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2011
- 2011-01-24 US US12/931,068 patent/US8252578B2/en not_active Expired - Fee Related
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2012
- 2012-07-19 US US13/553,321 patent/US8507435B2/en not_active Expired - Fee Related
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| WO2002051438A2 (en) * | 2000-12-22 | 2002-07-04 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Use of repulsive guidance molecule (rgm) and its modulators |
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Also Published As
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| US20100068803A1 (en) | 2010-03-18 |
| US8507435B2 (en) | 2013-08-13 |
| AU2010202722A1 (en) | 2010-07-15 |
| WO2004092405A2 (en) | 2004-10-28 |
| US20110212107A1 (en) | 2011-09-01 |
| EP1618131A2 (en) | 2006-01-25 |
| CA2522680A1 (en) | 2004-10-28 |
| US7893206B2 (en) | 2011-02-22 |
| EP2006298A3 (en) | 2009-04-22 |
| US8080651B2 (en) | 2011-12-20 |
| AU2010202722B2 (en) | 2012-12-20 |
| US20070166711A1 (en) | 2007-07-19 |
| EP2006298A2 (en) | 2008-12-24 |
| JP2006523440A (ja) | 2006-10-19 |
| WO2004092405A3 (en) | 2005-05-06 |
| US20100041139A1 (en) | 2010-02-18 |
| US20120301485A1 (en) | 2012-11-29 |
| US7511018B2 (en) | 2009-03-31 |
| US20090227502A1 (en) | 2009-09-10 |
| AU2004231122A1 (en) | 2004-10-28 |
| US8252578B2 (en) | 2012-08-28 |
| US20060073497A1 (en) | 2006-04-06 |
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