AU2004217969B2 - Thiolactones - Google Patents
Thiolactones Download PDFInfo
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- AU2004217969B2 AU2004217969B2 AU2004217969A AU2004217969A AU2004217969B2 AU 2004217969 B2 AU2004217969 B2 AU 2004217969B2 AU 2004217969 A AU2004217969 A AU 2004217969A AU 2004217969 A AU2004217969 A AU 2004217969A AU 2004217969 B2 AU2004217969 B2 AU 2004217969B2
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| US20080287866A1 (en) * | 2007-01-31 | 2008-11-20 | Adam Heller | Methods and compositions for the treatment of pain |
| WO2017029399A1 (en) | 2015-08-20 | 2017-02-23 | Universität Zu Köln | Pain tracking by pet-imaging (pain-trap) |
| WO2021155167A1 (en) * | 2020-01-31 | 2021-08-05 | The Johns Hopkins University | Bile acid-gcpii inhibitor conjugates to treat inflammatory diseases |
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| WO2001091738A2 (en) * | 2000-05-30 | 2001-12-06 | Guilford Pharmaceuticals Inc. | Naaladase inhibitors for treating amyotrophic lateral sclerosis |
| FR2819253A1 (fr) * | 2001-01-11 | 2002-07-12 | Servier Lab | Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
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| JPH0532659A (ja) * | 1991-08-01 | 1993-02-09 | Tsumura & Co | 糖尿病治療剤 |
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| GB9602721D0 (en) | 1996-02-09 | 1996-04-10 | Pharmacia Spa | Biologically active ureido derivatives useful in the treatment of multiple sclerosis |
| US5795877A (en) | 1996-12-31 | 1998-08-18 | Guilford Pharmaceuticals Inc. | Inhibitors of NAALADase enzyme activity |
| US5804602A (en) | 1996-06-17 | 1998-09-08 | Guilford Pharmaceuticals Inc. | Methods of cancer treatment using naaladase inhibitors |
| US5902817A (en) | 1997-04-09 | 1999-05-11 | Guilford Pharmaceuticals Inc. | Certain sulfoxide and sulfone derivatives |
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| US6025345A (en) | 1996-06-17 | 2000-02-15 | Guilford Pharmaceuticals Inc. | Inhibitors of NAALADase enzyme activity |
| US5863536A (en) | 1996-12-31 | 1999-01-26 | Guilford Pharmaceuticals Inc. | Phosphoramidate derivatives |
| TR199802638T2 (xx) | 1996-06-17 | 1999-03-22 | Guilford Pharmaceuticals, Inc. | Kanser tedavisinde naaladase inhibit�rleri kullan�m�. |
| US6017903A (en) | 1996-09-27 | 2000-01-25 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors |
| US5977090A (en) | 1996-09-27 | 1999-11-02 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of treating compulsive disorders using NAALADase inhibitors |
| US6071965A (en) | 1996-06-17 | 2000-06-06 | Guilford Pharmaceuticals Inc. | Phosphinic alkanoic acid derivatives |
| US6025344A (en) | 1996-06-17 | 2000-02-15 | Guilford Pharmaceuticals Inc. | Certain dioic acid derivatives useful as NAALADase inhibitors |
| US6054444A (en) | 1997-04-24 | 2000-04-25 | Guilford Pharmaceuticals Inc. | Phosphonic acid derivatives |
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| PL332413A1 (en) | 1996-09-27 | 1999-09-13 | Guilford Pharm Inc | Compositions containing inhibitors of naaladase as well as methods of treating glutamatic anomaly and influencing neuronic functions among animals |
| US5962521A (en) | 1997-04-04 | 1999-10-05 | Guilford Pharmaceuticals Inc. | Hydroxamic acid derivatives |
| US5981209A (en) | 1997-12-04 | 1999-11-09 | Guilford Pharmaceuticals Inc. | Use of NAALADase activity to identify prostate cancer and benign prostatic hyperplasia |
| US6028216A (en) | 1997-12-31 | 2000-02-22 | Guilford Pharmaceuticals Inc. | Asymmetric syntheses and intermediates for preparing enantiomer-enriched hydroxyphosphinyl derivatives |
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| US6395718B1 (en) | 1998-07-06 | 2002-05-28 | Guilford Pharmaceuticals Inc. | Pharmaceutical compositions and methods of inhibiting angiogenesis using naaladase inhibitors |
| EP1093453B1 (en) * | 1998-07-06 | 2005-09-28 | Guilford Pharmaceuticals Inc. | Naaladase inhibitors useful as pharmaceutical compounds and compositions |
| US6265609B1 (en) * | 1998-07-06 | 2001-07-24 | Guilford Pharmaceuticals Inc. | Thio-substituted pentanedioic acid derivatives |
| US6444657B1 (en) | 1998-12-31 | 2002-09-03 | Guilford Pharmaceuticals Inc. | Methods for treating certain diseases using naaladase inhibitors |
| US6479470B1 (en) * | 1999-04-28 | 2002-11-12 | Georgetown University | Ligands for metabotropic glutamate receptors and inhibitors of NAALAdase |
| US6228888B1 (en) * | 1999-07-01 | 2001-05-08 | Guilford Pharmaceuticals Inc. | Methods for treating anxiety, anxiety disorders and memory impairment using naaladase inhibitors |
| US6313159B1 (en) | 1999-08-20 | 2001-11-06 | Guilford Pharmaceuticals Inc. | Metabotropic glutamate receptor ligand derivatives as naaladase inhibitors |
| US6348464B1 (en) | 1999-11-12 | 2002-02-19 | Guilford Pharmaceuticals, Inc. | Pyrrolecarbonylimino derivatives as naaladase inhibitors |
| AU6661901A (en) | 2000-05-30 | 2001-12-11 | Guilford Pharm Inc | Naaladase inhibitors for treating retinal disorders and glaucoma |
| WO2001092273A2 (en) | 2000-05-30 | 2001-12-06 | Guilford Pharmaceuticals Inc. | Benzenedicarboxylic acid derivatives |
| ES2288550T3 (es) * | 2001-01-08 | 2008-01-16 | Pathway Intermediates Limited | Compuestos autoinductores y sus utilizaciones. |
| JP4234430B2 (ja) * | 2001-01-17 | 2009-03-04 | エムジーアイ ジーピー インコーポレイティッド | チオールを含むｎａａｌａｄアーゼ抑制物質 |
| JP4625236B2 (ja) | 2001-05-11 | 2011-02-02 | エーザイ インコーポレーテッド | ＮＡＡＬＡＤａｓｅ阻害剤としてのヒドロキサム酸およびアシルヒドロキサミン |
| PT1406867E (pt) | 2001-05-30 | 2009-02-25 | Eisai Corp North America | Derivados do ácido tiolalquilbenzóico |
| US20050080139A1 (en) | 2001-12-28 | 2005-04-14 | Slusher Barbara S. | Naaladase inhibitors for treating huntington's disease |
| WO2004078180A2 (en) | 2003-03-03 | 2004-09-16 | Guilford Pharmaceuticals Inc. | Naaladase inhibitors for treating opioid tolerance |
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Patent Citations (3)
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|---|---|---|---|---|
| US4239636A (en) * | 1978-10-23 | 1980-12-16 | Exxon Research & Engineering Co. | Thio-bis-(alkyl lactone acid esters) and thio-bis-(hydrocarbyl diacid esters) are useful additives for lubricating compositions |
| WO2001091738A2 (en) * | 2000-05-30 | 2001-12-06 | Guilford Pharmaceuticals Inc. | Naaladase inhibitors for treating amyotrophic lateral sclerosis |
| FR2819253A1 (fr) * | 2001-01-11 | 2002-07-12 | Servier Lab | Nouveaux derives d'acide hydroxamique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
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| Takahata H et al, Heterocycles (1986) vol 24 no 12 pp 3347-3350 * |
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| AU2004217969A1 (en) | 2004-09-16 |
| PL1599461T3 (pl) | 2009-10-30 |
| US7125907B2 (en) | 2006-10-24 |
| EP1599461B1 (en) | 2009-06-10 |
| CA2518234A1 (en) | 2004-09-16 |
| ES2326083T3 (es) | 2009-09-30 |
| US7968593B2 (en) | 2011-06-28 |
| US20050004203A1 (en) | 2005-01-06 |
| US20080004334A1 (en) | 2008-01-03 |
| ATE433445T1 (de) | 2009-06-15 |
| JP2006519858A (ja) | 2006-08-31 |
| DK1599461T3 (da) | 2009-08-17 |
| MXPA05009492A (es) | 2005-12-14 |
| CA2518234C (en) | 2012-11-13 |
| CY1109356T1 (el) | 2014-07-02 |
| US20100048667A1 (en) | 2010-02-25 |
| WO2004078742A1 (en) | 2004-09-16 |
| EP1599461A1 (en) | 2005-11-30 |
| EP1988088A1 (en) | 2008-11-05 |
| US7553866B2 (en) | 2009-06-30 |
| PT1599461E (pt) | 2009-07-20 |
| US20070037798A1 (en) | 2007-02-15 |
| SI1599461T1 (sl) | 2009-10-31 |
| JP4773951B2 (ja) | 2011-09-14 |
| DE602004021476D1 (de) | 2009-07-23 |
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Owner name: EISAI CORPORATION OF NORTH AMERICA Free format text: FORMER APPLICANT(S): MGI GP, INC. |
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