AU2003303648A1 - Novel 5-hydroxyindole-3-carboxylate derivatives - Google Patents

Novel 5-hydroxyindole-3-carboxylate derivatives

Info

Publication number
AU2003303648A1
AU2003303648A1 AU2003303648A AU2003303648A AU2003303648A1 AU 2003303648 A1 AU2003303648 A1 AU 2003303648A1 AU 2003303648 A AU2003303648 A AU 2003303648A AU 2003303648 A AU2003303648 A AU 2003303648A AU 2003303648 A1 AU2003303648 A1 AU 2003303648A1
Authority
AU
Australia
Prior art keywords
hydroxyindole
novel
carboxylate derivatives
carboxylate
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003303648A
Inventor
Ping Gong
Dun Wang
Yangfang Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHENYAND PHARMACEUTICAL UNIVERSITY
Original Assignee
SHENYAND PHARMACEUTICAL UNIVER
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHENYAND PHARMACEUTICAL UNIVER filed Critical SHENYAND PHARMACEUTICAL UNIVER
Publication of AU2003303648A1 publication Critical patent/AU2003303648A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
AU2003303648A 2003-01-04 2003-06-20 Novel 5-hydroxyindole-3-carboxylate derivatives Abandoned AU2003303648A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN03110803.2 2003-01-04
CNB031108032A CN100361975C (en) 2003-01-04 2003-01-04 Novel 5-hydroxy-3-carboxylate indoles derivant and method for preparing the same
PCT/CN2003/000481 WO2004060873A1 (en) 2003-01-04 2003-06-20 Novel 5-hydroxyindole-3-carboxylate derivatives

Publications (1)

Publication Number Publication Date
AU2003303648A1 true AU2003303648A1 (en) 2004-07-29

Family

ID=32076207

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003303648A Abandoned AU2003303648A1 (en) 2003-01-04 2003-06-20 Novel 5-hydroxyindole-3-carboxylate derivatives

Country Status (3)

Country Link
CN (1) CN100361975C (en)
AU (1) AU2003303648A1 (en)
WO (1) WO2004060873A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1560035A (en) * 2004-03-12 2005-01-05 沈阳药科大学 5-hydroxylic indole-3-carboxylic ester kind derivantion
WO2007075102A1 (en) * 2005-12-28 2007-07-05 Zakrytoe Aktsionernoe Obschestvo 'masterklon' Medicinal agent for treating viral infections
RU2330018C2 (en) * 2006-04-18 2008-07-27 Общество с ограниченной ответственностью "МБФ" Derivative 4-aminomethyl-6-bromine-5-hydroxyindole-3-carboxylate, methods of their obtaining (versions) and their application
WO2007136302A2 (en) * 2006-05-23 2007-11-29 Alla Chem, Llc Active substances, pharmaceutical composition and a method for the production and use thereof
US8329689B2 (en) 2006-05-23 2012-12-11 Alexandre Vasilievich Ivachtchenko Substituted indoles and a method for the production and use thereof
RU2386616C2 (en) 2008-04-23 2010-04-20 Общество С Ограниченной Ответственностью "Бинатех" Derivatives of 5-hydroxy-4-aminomethyl-1-cyclohexyl (or cycloheptyl)-3-alkoxycarbonylindoles, pharmaceutically acceptable salts thereof, having antiviral activity and method of producing said compounds
CN102260205A (en) * 2011-09-01 2011-11-30 湖北丽益医药科技有限公司 Method for synthesizing Arbidol mesylate
CN102924443B (en) * 2012-11-15 2015-03-25 沈阳药科大学 5-hydroxy indole derivative contain heterocyclic ring and applications thereof
CN104530479A (en) * 2014-12-19 2015-04-22 江苏华宏实业集团有限公司 Antibacterial agent for antibacterial plastic
CN104448687A (en) * 2014-12-19 2015-03-25 江苏华宏实业集团有限公司 Preparation method of antibacterial plastic
CN104479286A (en) * 2014-12-19 2015-04-01 江苏华宏实业集团有限公司 Antimicrobial plastic
CN108276323B (en) * 2018-02-05 2020-12-29 北京交通大学 3-functionalized N (O, S) -heteroandene derivatives and application thereof in respiratory syncytial virus resistance
CN113402440A (en) * 2021-06-23 2021-09-17 山东大学 5-hydroxymethyl-2-mercaptomethyl-1-methyl-1H-indole-3-carboxylic acid ethyl ester derivative and preparation and application thereof
CN113845464B (en) * 2021-10-28 2023-05-02 西安交通大学 Indolyl guanidine compound and preparation method and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1685933A1 (en) * 1974-11-27 1991-10-23 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе Chlorohydrate of 1-methyl-2-phenylthiomethyl-3-carboethoxy-4 -dimethylaminomethyl-5-oxy-6-bromoindole having antivirus action and method for obtaining it
WO1990008135A1 (en) * 1989-01-12 1990-07-26 Vsesojuzny Nauchno-Issledovatelsky Khimiko-Farmatsevtichesky Institut Imeni S.Ordzhonikidze (Vnikhfi) Ethyl ester 6-bromine-5-hydroxy-4-dimethyl-aminomethyl-1-methyl-2-phenylthiomethyl indole-3-carboxylic acid hydrochloride monohydrate, method of obtaining it and a pharmaceutical preparation of antiviral, interferon inducing and immunomodulating action based on it

Also Published As

Publication number Publication date
CN1482118A (en) 2004-03-17
WO2004060873A1 (en) 2004-07-22
CN100361975C (en) 2008-01-16

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase