CN104530479A - Antibacterial agent for antibacterial plastic - Google Patents
Antibacterial agent for antibacterial plastic Download PDFInfo
- Publication number
- CN104530479A CN104530479A CN201410800605.9A CN201410800605A CN104530479A CN 104530479 A CN104530479 A CN 104530479A CN 201410800605 A CN201410800605 A CN 201410800605A CN 104530479 A CN104530479 A CN 104530479A
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- Prior art keywords
- antibacterial
- methyl
- plastic
- antibiotic plastic
- agent
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to application of 1-ethyl-4-[(4-methyl-1-piperazinyl) methyl]-2-[(2,6-dichlorophenyl) s-methyl]-5-hydroxy-6-bromine-1H-benzpyrole-3-carboxylic acid ethyl ester cystamine dihydrochloride used as an antibacterial agent for antibacterial plastic. The antibacterial plastic provided by the invention has excellent antibacterial property, and has a wide prospect in industrial application.
Description
Technical field
The present invention relates to plastic applications, specifically, the present invention relates to a kind of antibiotic plastic antiseptic-germicide.
Background technology
Along with improving constantly of living standards of the people, people are to environmental health and the healthy pay attention to day by day of oneself.Meanwhile, industrialized fast development brings various problem of environmental pollution, and along with the appearance of these problem of environmental pollutions, a large amount of pathogenic bacterium and conditioned pathogen spread in each corner of human lives.When on the surface that these unwanted bacterias adhere to the normal household goods of mouth, will breed rapidly when condition is suitable and along with the contact of people spreading and propagation, harm humans is healthy.How to adopt easier method to make mouth often use the article of contact, especially plastics, obtain the anti-microbial property meeting service requirements, become a reality and urgent problem.
Summary of the invention
The object of the present invention is to provide a kind of antibiotic plastic antiseptic-germicide.
In order to realize object of the present invention, the invention provides 1-ethyl-4-[(4-methyl isophthalic acid-piperazinyl) methyl]-2-[(2,6-dichlorophenyl) thiomethyl]-5-hydroxyl-6-bromo-1H-Indole-3-Carboxylic Acid ethyl ester dihydrochloride and be used as the purposes in antibiotic plastic antiseptic-germicide.
Antibiotic plastic of the present invention has excellent germ resistance, and industrial application has broad prospects.
Embodiment
Below by way of the description of embodiment, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
Embodiment 1
Take ABS 500 kilograms, styrene-maleic anhydride copolymer 12 kilograms, MBS 16 kilograms, Tristearoylglycerol 5 kilograms, 4,4 '-thiobis (the 6-tertiary butyl-3-methylphenol) 21 kilograms, dimethyl silicone oil 0.6 kilogram and 1-ethyl-4-[(4-methyl isophthalic acid-piperazinyl) methyl]-2-[(2,6-dichlorophenyl) thiomethyl]-5-hydroxyl-6-bromo-1H-Indole-3-Carboxylic Acid ethyl ester dihydrochloride 0.01 kilogram.Be poured in barrel by the mixture that early-stage preparations are good, cylinder bake out temperature is set to 80 DEG C, and with gas blower air-supply, starts injection operation after drying 50min, uses HF-650 type horizontal toggle injection moulding machine in Haifeng county, Ningbo to prepare sample.
Embodiment 2
Prepare antibiotic plastic according to the mode identical with embodiment 1, difference is not use antiseptic-germicide.
Experimental example
By company standard QB/T2591-2003 " antibiotic plastic-Anti-microbial Performance Tests method and antibacterial effect ", intestinal bacteria ATCC 25922 is used to test.Result is as follows: the antibiotic plastic of embodiment 1 after 24 hours test specimen colony number (CFU/ sheet) is 8, and the antibiotic plastic of embodiment 2 after 24 hours test specimen colony number (CFU/ sheet) be 2.4 × 10
5.The result of embodiment 1 and the result of embodiment 2 compare, and difference has statistical significance (P < 0.05).
Claims (1)
1.1-ethyl-4-[(4-methyl isophthalic acid-piperazinyl) methyl]-2-[(2,6-dichlorophenyl) thiomethyl]-5-hydroxyl-6-bromo-1H-Indole-3-Carboxylic Acid ethyl ester dihydrochloride is being used as the purposes in antibiotic plastic antiseptic-germicide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410800605.9A CN104530479A (en) | 2014-12-19 | 2014-12-19 | Antibacterial agent for antibacterial plastic |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410800605.9A CN104530479A (en) | 2014-12-19 | 2014-12-19 | Antibacterial agent for antibacterial plastic |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104530479A true CN104530479A (en) | 2015-04-22 |
Family
ID=52846129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410800605.9A Pending CN104530479A (en) | 2014-12-19 | 2014-12-19 | Antibacterial agent for antibacterial plastic |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104530479A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1482118A (en) * | 2003-01-04 | 2004-03-17 | 沈阳药科大学 | Novel 5-hydroxy-3-carboxylate indoles derivant and method for preparing the same |
| CN102321275A (en) * | 2011-10-31 | 2012-01-18 | 吴江市天源塑胶有限公司 | Mildew-proof agent for plastics and preparation method for mildew-proof agent |
| CN103289123A (en) * | 2013-06-24 | 2013-09-11 | 苏州新区佳合塑胶有限公司 | Antimildew agent for plastic, and preparation method thereof |
-
2014
- 2014-12-19 CN CN201410800605.9A patent/CN104530479A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1482118A (en) * | 2003-01-04 | 2004-03-17 | 沈阳药科大学 | Novel 5-hydroxy-3-carboxylate indoles derivant and method for preparing the same |
| CN102321275A (en) * | 2011-10-31 | 2012-01-18 | 吴江市天源塑胶有限公司 | Mildew-proof agent for plastics and preparation method for mildew-proof agent |
| CN103289123A (en) * | 2013-06-24 | 2013-09-11 | 苏州新区佳合塑胶有限公司 | Antimildew agent for plastic, and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 邱峰: "《天然药物化学》", 31 August 2013, 清华大学出版社 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150422 |
|
| WD01 | Invention patent application deemed withdrawn after publication |