AU2003297997A1 - Methods for rapid detection and identification of bioagents for environmental and product testing - Google Patents

Methods for rapid detection and identification of bioagents for environmental and product testing

Info

Publication number
AU2003297997A1
AU2003297997A1 AU2003297997A AU2003297997A AU2003297997A1 AU 2003297997 A1 AU2003297997 A1 AU 2003297997A1 AU 2003297997 A AU2003297997 A AU 2003297997A AU 2003297997 A AU2003297997 A AU 2003297997A AU 2003297997 A1 AU2003297997 A1 AU 2003297997A1
Authority
AU
Australia
Prior art keywords
bioagents
environmental
identification
methods
rapid detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003297997A
Other languages
English (en)
Other versions
AU2003297997A8 (en
Inventor
Lawrence B. Blyn
Stanley T. Crooke
David J. Ecker
Richard H. Griffey
Thomas A. Hall
Steven A. Hofstadler
John Mcneil
Rangarajan Sampath
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ionis Pharmaceuticals Inc
Original Assignee
Isis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/326,047 external-priority patent/US20030190605A1/en
Application filed by Isis Pharmaceuticals Inc filed Critical Isis Pharmaceuticals Inc
Publication of AU2003297997A1 publication Critical patent/AU2003297997A1/en
Publication of AU2003297997A8 publication Critical patent/AU2003297997A8/xx
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
AU2003297997A 2002-12-06 2003-12-05 Methods for rapid detection and identification of bioagents for environmental and product testing Abandoned AU2003297997A1 (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US43131902P 2002-12-06 2002-12-06
US60/431,319 2002-12-06
US32318602A 2002-12-18 2002-12-18
US10/326,642 2002-12-18
US10/326,047 US20030190605A1 (en) 2001-03-02 2002-12-18 Methods for rapid detection and identification of bioagents for environmental testing
US10/326,642 US20040121314A1 (en) 2002-12-06 2002-12-18 Methods for rapid detection and identification of bioagents in containers
US10/323,186 2002-12-18
US10/326,047 2002-12-18
US44378803P 2003-01-30 2003-01-30
US60/443,788 2003-01-30
US45360703P 2003-03-10 2003-03-10
US60/453,607 2003-03-10
US45416503P 2003-03-12 2003-03-12
US60/454,165 2003-03-12
US10/660,996 US7255992B2 (en) 2001-03-02 2003-09-12 Methods for rapid detection and identification of bioagents for environmental and product testing
US10/660,996 2003-09-12
PCT/US2003/038757 WO2004053076A2 (en) 2002-12-06 2003-12-05 Methods for rapid detection and identification of bioagents for environmental and product testing

Publications (2)

Publication Number Publication Date
AU2003297997A1 true AU2003297997A1 (en) 2004-06-30
AU2003297997A8 AU2003297997A8 (en) 2004-06-30

Family

ID=32512824

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003297997A Abandoned AU2003297997A1 (en) 2002-12-06 2003-12-05 Methods for rapid detection and identification of bioagents for environmental and product testing

Country Status (3)

Country Link
US (4) US20040121314A1 (US20040121314A1-20040624-P00816.png)
AU (1) AU2003297997A1 (US20040121314A1-20040624-P00816.png)
WO (1) WO2004053076A2 (US20040121314A1-20040624-P00816.png)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110166040A1 (en) * 1997-09-05 2011-07-07 Ibis Biosciences, Inc. Compositions for use in identification of strains of e. coli o157:h7
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US20040121309A1 (en) * 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US7718354B2 (en) 2001-03-02 2010-05-18 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
CA2348042A1 (en) 2001-06-04 2002-12-04 Ann Huletsky Sequences for detection and identification of methicillin-resistant staphylococcus aureus
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
US8046171B2 (en) 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US20100129811A1 (en) * 2003-09-11 2010-05-27 Ibis Biosciences, Inc. Compositions for use in identification of pseudomonas aeruginosa
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US20120122099A1 (en) 2003-09-11 2012-05-17 Rangarajan Sampath Compositions for use in identification of bacteria
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
US10620202B2 (en) * 2004-04-15 2020-04-14 Institute For Environmental Health, Inc. Method for confirming the presence of an analyte
DK1745139T3 (da) 2004-04-15 2012-09-17 Inst Environmental Health Inc Trendanalyse og statistisk processtyring ved brug af multimålsat-screeningsassays
EP2458619B1 (en) * 2004-05-24 2017-08-02 Ibis Biosciences, Inc. Mass spectrometry with selective ion filtration by digital thresholding
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
WO2006135400A2 (en) 2004-08-24 2006-12-21 Isis Pharmaceuticals, Inc. Methods for rapid identification of recombinant organisms
US7888011B2 (en) * 2004-10-18 2011-02-15 U.S. Genomics, Inc. Methods for isolation of nucleic acids from prokaryotic spores
US20060205040A1 (en) 2005-03-03 2006-09-14 Rangarajan Sampath Compositions for use in identification of adventitious viruses
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
CA2605021A1 (en) * 2005-04-13 2007-08-02 Isis Pharmaceuticals, Inc. Compositions for use in identification of adenoviruses
AU2006272776B2 (en) 2005-07-21 2012-01-19 Ibis Biosciences, Inc. Methods for rapid identification and quantitation of nucleic acid variants
US20070111234A1 (en) * 2005-09-12 2007-05-17 Christian Birkner Detection of biological DNA
US11834720B2 (en) * 2005-10-11 2023-12-05 Geneohm Sciences, Inc. Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx
KR100659261B1 (ko) * 2006-02-07 2006-12-20 한국기초과학지원연구원 탠덤 푸리에변환 이온 사이클로트론 공명 질량 분석기
US8088582B2 (en) 2006-04-06 2012-01-03 Ibis Biosciences, Inc. Compositions for the use in identification of fungi
WO2007133189A2 (en) * 2006-05-01 2007-11-22 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services,Centers For Disease Control And Prevention Methods and agents for detecting parechovirus
US8679741B2 (en) * 2006-05-31 2014-03-25 Sequenom, Inc. Methods and compositions for the extraction and amplification of nucleic acid from a sample
WO2007147063A2 (en) * 2006-06-16 2007-12-21 Sequenom, Inc. Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample
EP3159417B1 (en) 2006-08-01 2021-10-06 Gen-Probe Incorporated Methods of nonspecific target capture of nucleic acids
AU2007353877B2 (en) 2006-09-14 2012-07-19 Ibis Biosciences, Inc. Targeted whole genome amplification method for identification of pathogens
US8148511B2 (en) * 2006-09-28 2012-04-03 The University Of North Carolina At Chapel Hill Methods and compositions for the detection and quantification of E. coli and Enterococcus
US7902345B2 (en) 2006-12-05 2011-03-08 Sequenom, Inc. Detection and quantification of biomolecules using mass spectrometry
US8076104B2 (en) * 2007-01-25 2011-12-13 Rogan Peter K Rapid and comprehensive identification of prokaryotic organisms
JP5680304B2 (ja) 2007-02-23 2015-03-04 アイビス バイオサイエンシズ インコーポレイティッド 迅速な法医学的ｄｎａ分析法
WO2008118988A1 (en) 2007-03-26 2008-10-02 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US7811766B2 (en) * 2007-03-28 2010-10-12 Thinkvillage, Llc Genetic identification and validation of Echinacea species
US8527207B2 (en) * 2007-05-15 2013-09-03 Peter K. Rogan Accurate identification of organisms based on individual information content
US20100291544A1 (en) * 2007-05-25 2010-11-18 Ibis Biosciences, Inc. Compositions for use in identification of strains of hepatitis c virus
WO2008151023A2 (en) 2007-06-01 2008-12-11 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
US20110045456A1 (en) * 2007-06-14 2011-02-24 Ibis Biosciences, Inc. Compositions for use in identification of adventitious contaminant viruses
AU2008275195A1 (en) * 2007-07-06 2009-01-15 The Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Northern Arizona University Burkholderia pseudomallei diagnostic genetic elements that predict mortality in melioidosis
ATE549419T1 (de) 2007-08-29 2012-03-15 Sequenom Inc Verfahren und zusammensetzungen für die universelle grössenspezifische polymerasekettenreaktion
WO2009131728A2 (en) * 2008-01-29 2009-10-29 Ibis Biosciences, Inc. Compositions for use in identification of picornaviruses
US20090263809A1 (en) * 2008-03-20 2009-10-22 Zygem Corporation Limited Methods for Identification of Bioagents
AU2009228312B2 (en) 2008-03-26 2015-05-21 Sequenom, Inc. Restriction endonuclease enhanced polymorphic sequence detection
US9200329B2 (en) 2008-05-19 2015-12-01 Biofire Diagnostics, Llc Rapid epidemiologic typing of bacteria
US20110143358A1 (en) * 2008-05-30 2011-06-16 Ibis Biosciences, Inc. Compositions for use in identification of tick-borne pathogens
WO2009151982A1 (en) * 2008-05-30 2009-12-17 Ibis Biosciences, Inc. Compositions for use in identification of francisella
WO2009148995A2 (en) * 2008-06-02 2009-12-10 Ibis Biosciences, Inc. Compositions for use in identification of adventitious viruses
US8148163B2 (en) 2008-09-16 2012-04-03 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
EP2349549B1 (en) 2008-09-16 2012-07-18 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, and system
EP2344893B1 (en) 2008-09-16 2014-10-15 Ibis Biosciences, Inc. Microplate handling systems and methods
WO2010039755A1 (en) * 2008-10-02 2010-04-08 Ibis Biosciences, Inc. Compositions for use in identification of members of the bacterial genus mycoplasma
WO2010039696A1 (en) * 2008-10-02 2010-04-08 Ibis Biosciences, Inc. Compositions for use in identification of herpesviruses
US20110190170A1 (en) * 2008-10-03 2011-08-04 Ibis Biosciences, Inc. Compositions for use in identification of antibiotic-resistant bacteria
WO2010039775A1 (en) * 2008-10-03 2010-04-08 Ibis Biosciences, Inc. Compositions for use in identification of members of the bacterial class alphaproteobacter
US20110183345A1 (en) * 2008-10-03 2011-07-28 Ibis Biosciences, Inc. Compositions for use in identification of streptococcus pneumoniae
WO2010039870A1 (en) * 2008-10-03 2010-04-08 Ibis Biosciences, Inc. Compositions for use in identification of neisseria, chlamydia, and/or chlamydophila bacteria
US20110183344A1 (en) * 2008-10-03 2011-07-28 Rangarajan Sampath Compositions for use in identification of clostridium difficile
JP2012512665A (ja) * 2008-12-19 2012-06-07 アボット・ラボラトリーズ ヒトｋ−ｒａｓのコドン１２−１３における突然変異の診断試験
WO2010080616A1 (en) 2008-12-19 2010-07-15 Abbott Laboratories Molecular assay for diagnosis of malaria
EP2396803A4 (en) 2009-02-12 2016-10-26 Ibis Biosciences Inc IONIZATION PROBE ASSEMBLIES
WO2010104798A1 (en) 2009-03-08 2010-09-16 Ibis Biosciences, Inc. Bioagent detection methods
US9393564B2 (en) 2009-03-30 2016-07-19 Ibis Biosciences, Inc. Bioagent detection systems, devices, and methods
EP3211095B1 (en) 2009-04-03 2019-01-02 Sequenom, Inc. Nucleic acid preparation compositions and methods
US8950604B2 (en) 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
WO2011008972A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systems for bioagent identification
WO2011014811A1 (en) 2009-07-31 2011-02-03 Ibis Biosciences, Inc. Capture primers and capture sequence linked solid supports for molecular diagnostic tests
EP3098325A1 (en) 2009-08-06 2016-11-30 Ibis Biosciences, Inc. Non-mass determined base compositions for nucleic acid detection
US20110065111A1 (en) * 2009-08-31 2011-03-17 Ibis Biosciences, Inc. Compositions For Use In Genotyping Of Klebsiella Pneumoniae
ES2628739T3 (es) 2009-10-15 2017-08-03 Ibis Biosciences, Inc. Amplificación por desplazamiento múltiple
WO2011103144A1 (en) * 2010-02-16 2011-08-25 President And Fellows Of Harvard College Methods and systems for detection of microbes
WO2011112718A1 (en) 2010-03-10 2011-09-15 Ibis Biosciences, Inc. Production of single-stranded circular nucleic acid
US9758840B2 (en) * 2010-03-14 2017-09-12 Ibis Biosciences, Inc. Parasite detection via endosymbiont detection
US9068017B2 (en) 2010-04-08 2015-06-30 Ibis Biosciences, Inc. Compositions and methods for inhibiting terminal transferase activity
CN103717751A (zh) 2011-05-19 2014-04-09 塞昆纳姆股份有限公司 用于多重核酸鉴定的产品和方法
WO2013036603A1 (en) 2011-09-06 2013-03-14 Ibis Biosciences, Inc. Sample preparation methods
US20140228455A1 (en) * 2011-09-07 2014-08-14 Alpha Biotech Ab Determination of bacterial infections of the genus rickettsia and possibly borrelia, in patients exhibiting symptoms of disease and being blood donors
US9970061B2 (en) 2011-12-27 2018-05-15 Ibis Biosciences, Inc. Bioagent detection oligonucleotides
EP2901129A4 (en) 2012-09-26 2016-11-02 Ibis Biosciences Inc DUTCH INTERFACE FOR A MICROFLUIDIC DEVICE
WO2014186874A1 (en) 2013-05-23 2014-11-27 Yyz Pharmatech, Inc. Methods and compositions for enzyme linked immuno and hybridization mass spectrometric assay
WO2016172571A1 (en) 2015-04-24 2016-10-27 Agena Bioscience, Inc. Multiplexed method for the identification and quantitation of minor alleles and polymorphisms
CN107787371B (zh) 2015-04-24 2022-02-01 基纳生物技术有限公司 检测和定量次要变体的并行式方法
CN112646909A (zh) * 2021-01-05 2021-04-13 中国人民解放军军事科学院军事医学研究院 一种基于染色体上特异snp位点的炭疽芽胞杆菌鉴定方法

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567587A (en) * 1983-01-10 1996-10-22 Gen-Probe Incorporated Method for detecting, the presence and amount of prokaryotic organisms using specific rRNA subsequences as probes
US5270030A (en) * 1988-12-29 1993-12-14 Bio-Technology General Corp. Fibrin binding domain polypeptide and method of producing
WO1992013629A1 (en) * 1991-01-31 1992-08-20 Wayne State University A method for analyzing an organic sample
AU2580892A (en) * 1991-09-05 1993-04-05 Isis Pharmaceuticals, Inc. Determination of oligonucleotides for therapeutics, diagnostics and research reagents
ES2152933T3 (es) * 1991-10-23 2001-02-16 Baylor College Medicine Determinacion de huellas relativas a cepas bacterianas utilizando amplificacion de secuencias de adn repetitivas.
US5484908A (en) * 1991-11-26 1996-01-16 Gilead Sciences, Inc. Oligonucleotides containing 5-propynyl pyrimidines
DE637965T1 (de) * 1991-11-26 1995-12-14 Gilead Sciences Inc Gesteigerte bildung von triple- und doppelhelices aus oligomeren mit modifizierten pyrimidinen.
TW393513B (en) * 1991-11-26 2000-06-11 Isis Pharmaceuticals Inc Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines
US5981176A (en) * 1992-06-17 1999-11-09 City Of Hope Method of detecting and discriminating between nucleic acid sequences
US6436635B1 (en) * 1992-11-06 2002-08-20 Boston University Solid phase sequencing of double-stranded nucleic acids
US5503980A (en) * 1992-11-06 1996-04-02 Trustees Of Boston University Positional sequencing by hybridization
US6372424B1 (en) * 1995-08-30 2002-04-16 Third Wave Technologies, Inc Rapid detection and identification of pathogens
US6194144B1 (en) * 1993-01-07 2001-02-27 Sequenom, Inc. DNA sequencing by mass spectrometry
DE69433811T2 (de) * 1993-01-07 2005-06-23 Sequenom, Inc., San Diego Dns - sequenzierung durch massenspektronomie
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US6074823A (en) * 1993-03-19 2000-06-13 Sequenom, Inc. DNA sequencing by mass spectrometry via exonuclease degradation
AU687801B2 (en) * 1993-03-19 1998-03-05 Sequenom, Inc. DNA sequencing by mass spectrometry via exonuclease degradation
GB9315847D0 (en) * 1993-07-30 1993-09-15 Isis Innovation Tag reagent and assay method
US5527675A (en) * 1993-08-20 1996-06-18 Millipore Corporation Method for degradation and sequencing of polymers which sequentially eliminate terminal residues
US6376178B1 (en) * 1993-09-03 2002-04-23 Duke University Method of nucleic acid sequencing
US5502177A (en) * 1993-09-17 1996-03-26 Gilead Sciences, Inc. Pyrimidine derivatives for labeled binding partners
US5849492A (en) * 1994-02-28 1998-12-15 Phylogenetix Laboratories, Inc. Method for rapid identification of prokaryotic and eukaryotic organisms
US6001564A (en) * 1994-09-12 1999-12-14 Infectio Diagnostic, Inc. Species specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
GB9504598D0 (en) * 1995-03-03 1995-04-26 Imp Cancer Res Tech Method of nucleic acid analysis
US6428955B1 (en) * 1995-03-17 2002-08-06 Sequenom, Inc. DNA diagnostics based on mass spectrometry
US5625184A (en) * 1995-05-19 1997-04-29 Perseptive Biosystems, Inc. Time-of-flight mass spectrometry analysis of biomolecules
US5830655A (en) * 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US5700642A (en) * 1995-05-22 1997-12-23 Sri International Oligonucleotide sizing using immobilized cleavable primers
EP0837933A4 (en) * 1995-06-07 2003-05-21 Commw Scient Ind Res Org OPTIMIZED MINIZYMES AND MINIRIBOZYMES AND THE USE THEREOF
US5994066A (en) * 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US5869242A (en) * 1995-09-18 1999-02-09 Myriad Genetics, Inc. Mass spectrometry to assess DNA sequence polymorphisms
US5871697A (en) * 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US6312893B1 (en) * 1996-01-23 2001-11-06 Qiagen Genomics, Inc. Methods and compositions for determining the sequence of nucleic acid molecules
GB9602028D0 (en) * 1996-02-01 1996-04-03 Amersham Int Plc Nucleoside analogues
US6051378A (en) * 1996-03-04 2000-04-18 Genetrace Systems Inc. Methods of screening nucleic acids using mass spectrometry
AU2217597A (en) 1996-03-18 1997-10-22 Sequenom, Inc. Dna sequencing by mass spectrometry
US5928906A (en) * 1996-05-09 1999-07-27 Sequenom, Inc. Process for direct sequencing during template amplification
DE19633436A1 (de) * 1996-08-20 1998-02-26 Boehringer Mannheim Gmbh Verfahren zum Nachweis von Nukleinsäuren unter Ermittlung der Masse
US5965363A (en) * 1996-09-19 1999-10-12 Genetrace Systems Inc. Methods of preparing nucleic acids for mass spectrometric analysis
US5777324A (en) * 1996-09-19 1998-07-07 Sequenom, Inc. Method and apparatus for maldi analysis
WO1998012355A1 (en) 1996-09-19 1998-03-26 Genetrace Systems Methods of preparing nucleic acids for mass spectrometric analysis
US6361940B1 (en) * 1996-09-24 2002-03-26 Qiagen Genomics, Inc. Compositions and methods for enhancing hybridization and priming specificity
US5864137A (en) * 1996-10-01 1999-01-26 Genetrace Systems, Inc. Mass spectrometer
CA2270132A1 (en) 1996-11-06 1998-05-14 Sequenom, Inc. Dna diagnostics based on mass spectrometry
US6140053A (en) * 1996-11-06 2000-10-31 Sequenom, Inc. DNA sequencing by mass spectrometry via exonuclease degradation
US6046005A (en) * 1997-01-15 2000-04-04 Incyte Pharmaceuticals, Inc. Nucleic acid sequencing with solid phase capturable terminators comprising a cleavable linking group
US5876936A (en) * 1997-01-15 1999-03-02 Incyte Pharmaceuticals, Inc. Nucleic acid sequencing with solid phase capturable terminators
EP0998749A1 (en) 1997-05-30 2000-05-10 Genetrace Systems, Inc. Volatile matrices for matrix-assisted laser desorption/ionization mass spectrometry
WO1999014375A2 (en) 1997-09-19 1999-03-25 Genetrace Systems, Inc. Dna typing by mass spectrometry with polymorphic dna repeat markers
US6028183A (en) * 1997-11-07 2000-02-22 Gilead Sciences, Inc. Pyrimidine derivatives and oligonucleotides containing same
US6007992A (en) * 1997-11-10 1999-12-28 Gilead Sciences, Inc. Pyrimidine derivatives for labeled binding partners
US6268131B1 (en) * 1997-12-15 2001-07-31 Sequenom, Inc. Mass spectrometric methods for sequencing nucleic acids
GB9815166D0 (en) * 1998-07-13 1998-09-09 Brax Genomics Ltd Compounds for mass spectrometry
US6458533B1 (en) * 1997-12-19 2002-10-01 High Throughput Genomics, Inc. High throughput assay system for monitoring ESTs
JP2002505866A (ja) * 1998-03-10 2002-02-26 ラージ・スケール・プローティオーミックス・コーポレイション 微生物の検出および特性付与
US6270974B1 (en) * 1998-03-13 2001-08-07 Promega Corporation Exogenous nucleic acid detection
US6235480B1 (en) * 1998-03-13 2001-05-22 Promega Corporation Detection of nucleic acid hybrids
US6270973B1 (en) * 1998-03-13 2001-08-07 Promega Corporation Multiplex method for nucleic acid detection
US6312902B1 (en) * 1998-03-13 2001-11-06 Promega Corporation Nucleic acid detection
US6268146B1 (en) * 1998-03-13 2001-07-31 Promega Corporation Analytical methods and materials for nucleic acid detection
US6277578B1 (en) * 1998-03-13 2001-08-21 Promega Corporation Deploymerization method for nucleic acid detection of an amplified nucleic acid target
US6391551B1 (en) * 1998-03-13 2002-05-21 Promega Corporation Detection of nucleic acid hybrids
US6723564B2 (en) * 1998-05-07 2004-04-20 Sequenom, Inc. IR MALDI mass spectrometry of nucleic acids using liquid matrices
US6221587B1 (en) * 1998-05-12 2001-04-24 Isis Pharmceuticals, Inc. Identification of molecular interaction sites in RNA for novel drug discovery
US6468743B1 (en) * 1998-05-18 2002-10-22 Conagra Grocery Products Company PCR techniques for detecting microbial contaminants in foodstuffs
US6104028A (en) * 1998-05-29 2000-08-15 Genetrace Systems Inc. Volatile matrices for matrix-assisted laser desorption/ionization mass spectrometry
US6218118B1 (en) * 1998-07-09 2001-04-17 Agilent Technologies, Inc. Method and mixture reagents for analyzing the nucleotide sequence of nucleic acids by mass spectrometry
US6432651B1 (en) * 1998-07-10 2002-08-13 Cetek Corporation Method to detect and analyze tight-binding ligands in complex biological samples using capillary electrophoresis and mass spectrometry
WO2000020643A1 (en) * 1998-10-05 2000-04-13 Mosaic Technologies Reverse displacement assay for detection of nucleic acid sequences
US6153389A (en) * 1999-02-22 2000-11-28 Haarer; Brian K. DNA additives as a mechanism for unambiguously marking biological samples
US6436640B1 (en) * 1999-03-18 2002-08-20 Exiqon A/S Use of LNA in mass spectrometry
US6613509B1 (en) * 1999-03-22 2003-09-02 Regents Of The University Of California Determination of base (nucleotide) composition in DNA oligomers by mass spectrometry
US6649351B2 (en) * 1999-04-30 2003-11-18 Aclara Biosciences, Inc. Methods for detecting a plurality of analytes by mass spectrometry
ATE317024T1 (de) * 1999-12-29 2006-02-15 Keygene Nv Verfahren zur erzeugung von oligonukleotiden, im besonderen zur detektion amplifizierter restriktionsfragmente, die durch aflp erhalten wurden
WO2001051661A2 (en) * 2000-01-13 2001-07-19 Amsterdam Support Diagnostics B.V. A universal nucleic acid amplification system for nucleic acids in a sample
US6475736B1 (en) * 2000-05-23 2002-11-05 Variagenics, Inc. Methods for genetic analysis of DNA using biased amplification of polymorphic sites
ATE423221T1 (de) * 2000-06-13 2009-03-15 Univ Boston Verwendung von mass-matched nukleotide in der analyse von oligonukleotidmischungen sowie in der hoch-multiplexen nukleinsäuresequenzierung
US6811977B2 (en) * 2000-07-27 2004-11-02 California Institute Of Technology Rapid, quantitative method for the mass spectrometric analysis of nucleic acids for gene expression and genotyping
US6682889B1 (en) * 2000-11-08 2004-01-27 Becton, Dickinson And Company Amplification and detection of organisms of the Chlamydiaceae family
US20040038206A1 (en) * 2001-03-14 2004-02-26 Jia Zhang Method for high throughput assay of genetic analysis
US20020187477A1 (en) * 2001-06-06 2002-12-12 Hong Xue Method for detecting single nucleotide polymorphisms (SNPs) and point mutations
US20030039976A1 (en) * 2001-08-14 2003-02-27 Haff Lawrence A. Methods for base counting
US6869769B2 (en) * 2001-11-15 2005-03-22 Whatman, Inc. Methods and materials for detecting genetic material
US20030148284A1 (en) * 2001-12-17 2003-08-07 Vision Todd J. Solid phase detection of nucleic acid molecules

Also Published As

Publication number Publication date
US20040253619A1 (en) 2004-12-16
US7255992B2 (en) 2007-08-14
WO2004053076A3 (en) 2004-09-02
WO2004053076A2 (en) 2004-06-24
US20040180328A1 (en) 2004-09-16
US20040121314A1 (en) 2004-06-24
AU2003297997A8 (en) 2004-06-30
US20040253583A1 (en) 2004-12-16

Similar Documents

Publication Publication Date Title
AU2003297997A1 (en) Methods for rapid detection and identification of bioagents for environmental and product testing
AU2003299606A1 (en) Method for aberration detection and measurement
AU2003269809A1 (en) Method for rapid detection and identification of viral bioagents
AU2003228470A1 (en) Method and system for monitoring point of sale exceptions
IL238855A0 (en) A method for rapid detection and identification of biological agents
AU2003288104A1 (en) Method for detecting and tracking objects
EP1664837B8 (en) Object detection system and object detection method
AU2003219926A1 (en) Method and apparatus for recognizing objects
AU2003234289A1 (en) System and method for blackfield detection
AU2003239963A1 (en) Method and apparatus for detecting substances of interest
AU2003228868A1 (en) Method od feature identification and analysis
AU2002360828A1 (en) Method and apparatus for identifying complex objects based on range readings from multiple sensors
AU2003291081A1 (en) Identification apparatus and method
AU2003225165A1 (en) System and method of measuring molecular interactions
AU2003239534A1 (en) Methods and apparatus for accurate phase detection
AU2003300530A1 (en) Dhodh-inhibitors and method for their identification
AU2003281574A1 (en) Detection method and apparatus
AU2002368458A1 (en) Dynamic brand evaluation information processing apparatus and method
AU2003282945A1 (en) Method and apparatus for fingerprint detection
IL158097A (en) Method and system for detection of objects
AU2003208397A1 (en) Sensing apparatus and method
AU2003297889A1 (en) Method and apparatus for asperity detection
AU2003263271A1 (en) Method capable of being automated for detection of prpless thanspgreater thanresless than/spgreater than and uses thereof
AU2003214281A1 (en) Method and apparatus for sensing
AU2003232017A1 (en) Breaklock detection system and method

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase