AU2003297842A1 - Indolizine compounds - Google Patents

Indolizine compounds Download PDF

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Publication number
AU2003297842A1
AU2003297842A1 AU2003297842A AU2003297842A AU2003297842A1 AU 2003297842 A1 AU2003297842 A1 AU 2003297842A1 AU 2003297842 A AU2003297842 A AU 2003297842A AU 2003297842 A AU2003297842 A AU 2003297842A AU 2003297842 A1 AU2003297842 A1 AU 2003297842A1
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AU
Australia
Prior art keywords
substituted
compound
unsubstituted
group
aryl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003297842A
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English (en)
Inventor
Dinesh Chimmanamada
David James
Keizo Koya
Rongzhen Lu
Masazumi Nagai
Mitsunori Ono
Teresa Przewloka
Lijun Sun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synta Phamaceuticals Corp
Original Assignee
Synta Phamaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synta Phamaceuticals Corp filed Critical Synta Phamaceuticals Corp
Publication of AU2003297842A1 publication Critical patent/AU2003297842A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
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    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Virology (AREA)
AU2003297842A 2002-12-12 2003-12-10 Indolizine compounds Abandoned AU2003297842A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/319,401 US20040116462A1 (en) 2002-12-12 2002-12-12 Indolizine compounds
US10/319,401 2002-12-12
US10/388,332 2003-03-13
US10/388,332 US20030204090A1 (en) 2001-09-13 2003-03-13 Indolizine compounds
PCT/US2003/039303 WO2004054507A2 (en) 2002-12-12 2003-12-10 Indolizine compounds

Publications (1)

Publication Number Publication Date
AU2003297842A1 true AU2003297842A1 (en) 2004-07-09

Family

ID=32506644

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003297842A Abandoned AU2003297842A1 (en) 2002-12-12 2003-12-10 Indolizine compounds

Country Status (7)

Country Link
US (2) US20040116462A1 (https=)
EP (1) EP1569644A4 (https=)
JP (1) JP2006509842A (https=)
AU (1) AU2003297842A1 (https=)
CA (1) CA2509214A1 (https=)
TW (1) TW200418855A (https=)
WO (1) WO2004054507A2 (https=)

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US7384736B2 (en) * 2001-09-06 2008-06-10 Decode Genetics Ehf. Methods for predicting drug sensitivity in patients afflicted with an inflammatory disease
US6893828B2 (en) * 2001-09-06 2005-05-17 Decode Genetics Ehf. Methods for producing ex vivo models for inflammatory disease and uses thereof
US20040116462A1 (en) * 2002-12-12 2004-06-17 Mitsunori Ono Indolizine compounds
CA2459886A1 (en) * 2001-09-13 2003-03-20 Synta Pharmaceuticals Corp. 1-glyoxlylamide indolizines for treating cancer
DE10318611A1 (de) 2003-04-24 2004-11-11 Elbion Ag 4-, 6- oder 7-Hydroxyindole mit N-Oxidgruppen und deren Verwendung als Therapeutika
CA2549965A1 (en) * 2003-10-31 2005-05-19 Astrazeneca Ab Alkynes iii
US20100009928A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and taxanes and methods of use thereof
AU2005228410A1 (en) 2004-03-29 2005-10-13 University Of South Florida Effective treatment of tumors and cancer with triciribine and related compounds
US20100028339A1 (en) * 2004-03-29 2010-02-04 Cheng Jin Q Compositions including triciribine and trastuzumab and methods of use thereof
US20110008327A1 (en) 2004-03-29 2011-01-13 Cheng Jin Q Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US20100009929A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
US20100173864A1 (en) 2004-03-29 2010-07-08 Cheng Jin Q Compositions including triciribine and one or more platinum compounds and methods of use thereof
WO2005099824A1 (en) * 2004-03-30 2005-10-27 Synta Pharmaceuticals, Corp. 1-glyoxylamide indolizines for treating lung and ovarian cancer
JP2008539721A (ja) * 2005-05-02 2008-11-20 ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク アルツハイマー病の治療のためのホスホイノシチドモジュレーション
CA2608890C (en) * 2005-05-20 2011-08-02 Alantos-Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
US20070155738A1 (en) * 2005-05-20 2007-07-05 Alantos Pharmaceuticals, Inc. Heterobicyclic metalloprotease inhibitors
CN1870631B (zh) * 2005-11-11 2010-04-14 华为技术有限公司 媒体网关的门控方法
AR077428A1 (es) 2009-07-29 2011-08-24 Sanofi Aventis (aza) indolizinacarboxamidas ciclicas su preparacion y su uso como agentes farmaceuticos
CN101648953B (zh) * 2009-09-24 2012-09-05 绍兴文理学院 一种咪唑并[1，2-b]吡咯并[1，2-f]哒嗪衍生物及其制备方法和用途
FR2962438B1 (fr) 2010-07-06 2012-08-17 Sanofi Aventis Derives d'indolizines, procedes de preparation et application en therapeutique
EP3242878B1 (en) 2015-01-08 2020-10-14 Impetis Biosciences Ltd. Bicyclic compounds, compositions and medicinal applications thereof
EP4426291A4 (en) * 2021-11-03 2025-12-03 Tactogen Inc Indolizine compounds for the treatment of mental disorders or for mental improvement
US11530217B1 (en) 2022-06-29 2022-12-20 King Faisal University Antitubercular compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2287706A (en) * 1994-03-21 1995-09-27 Fujisawa Pharmaceutical Co Indolizine derivatives
BR9508298A (pt) * 1994-07-21 1998-11-03 Shionogi & Co Inibidores de indolizina de spla2
CA2459886A1 (en) * 2001-09-13 2003-03-20 Synta Pharmaceuticals Corp. 1-glyoxlylamide indolizines for treating cancer
US20040116462A1 (en) * 2002-12-12 2004-06-17 Mitsunori Ono Indolizine compounds

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WO2004054507A2 (en) 2004-07-01
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US20040116462A1 (en) 2004-06-17
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JP2006509842A (ja) 2006-03-23

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