AU2003291365B2 - Compositions and methods for treating or preventing pneumococcal infection - Google Patents
Compositions and methods for treating or preventing pneumococcal infection Download PDFInfo
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- AU2003291365B2 AU2003291365B2 AU2003291365A AU2003291365A AU2003291365B2 AU 2003291365 B2 AU2003291365 B2 AU 2003291365B2 AU 2003291365 A AU2003291365 A AU 2003291365A AU 2003291365 A AU2003291365 A AU 2003291365A AU 2003291365 B2 AU2003291365 B2 AU 2003291365B2
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- streptococcus pneumoniae
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Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Public Health (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US42449702P | 2002-11-07 | 2002-11-07 | |
| US60/424,497 | 2002-11-07 | ||
| PCT/US2003/035529 WO2004043376A2 (en) | 2002-11-07 | 2003-11-06 | Compositions and methods for treating or preventing pneumococcal infection |
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| AU2003291365A1 AU2003291365A1 (en) | 2004-06-03 |
| AU2003291365B2 true AU2003291365B2 (en) | 2009-06-11 |
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| AU2003291365A Expired AU2003291365B2 (en) | 2002-11-07 | 2003-11-06 | Compositions and methods for treating or preventing pneumococcal infection |
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| US (2) | US7217791B2 (OSRAM) |
| EP (1) | EP1558280B1 (OSRAM) |
| JP (3) | JP2006506989A (OSRAM) |
| KR (1) | KR20050086427A (OSRAM) |
| CN (1) | CN100443116C (OSRAM) |
| AU (1) | AU2003291365B2 (OSRAM) |
| CA (1) | CA2504938C (OSRAM) |
| ES (1) | ES2451620T3 (OSRAM) |
| TW (1) | TWI315986B (OSRAM) |
| WO (1) | WO2004043376A2 (OSRAM) |
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| CA2683748C (en) | 2007-04-13 | 2016-02-16 | The Board Of Regents Of The University Of Oklahoma | Mutants of cholesterol-dependent cytolysins and uses thereof |
| GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| EP2252326A4 (en) * | 2008-02-01 | 2012-08-29 | Newcastle Innovation Ltd | VACCINE COMPOSITIONS |
| US20120064103A1 (en) | 2009-03-24 | 2012-03-15 | Novartis Ag | Combinations of meningococcal factor h binding protein and pneumococcal saccharide conjugates |
| AU2010293902A1 (en) | 2009-09-10 | 2012-03-22 | Novartis Ag | Combination vaccines against respiratory tract diseases |
| GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
| WO2011112906A2 (en) | 2010-03-12 | 2011-09-15 | Children's Medical Center Corporation | Novel immunogens and methods for discovery and screening thereof |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| CA2833409A1 (en) * | 2011-04-21 | 2012-10-26 | The Rockefeller University | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
| AU2012257771C1 (en) | 2011-05-17 | 2015-12-03 | Glaxosmithkline Biologicals S.A. | Vaccine against Streptococcus pneumoniae |
| ES2826393T3 (es) * | 2011-10-05 | 2021-05-18 | Univ Rockefeller | Lisinas de bacteriófago diméricas |
| EP2822586A1 (en) | 2012-03-07 | 2015-01-14 | Novartis AG | Adjuvanted formulations of streptococcus pneumoniae antigens |
| ES2959258T3 (es) | 2013-02-07 | 2024-02-22 | Childrens Medical Center | Antígenos proteicos que proporcionan protección contra la colonización y/o la enfermedad neumocócicas |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| AU2015349787B2 (en) | 2014-11-21 | 2021-07-29 | The Board Of Regents Of The University Of Oklahoma | Pneumolysin mutants and methods of use thereof |
| GB201610599D0 (en) * | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
| US11998599B2 (en) | 2016-12-30 | 2024-06-04 | Vaxcyte, Inc. | Polypeptide-antigen conjugates with non-natural amino acids |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| RS65893B1 (sr) | 2017-09-07 | 2024-09-30 | Merck Sharp & Dohme Llc | Pneumokokni polisaharidi i njihova primena u imunogenim konjugatima polisaharid-proteinski nosač |
| WO2020056202A1 (en) | 2018-09-12 | 2020-03-19 | Affinivax, Inc. | Multivalent pneumococcal vaccines |
| KR20240099160A (ko) | 2021-09-09 | 2024-06-28 | 아피니백스, 인크. | 다가 폐렴구균 백신 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0687688A1 (en) * | 1993-12-17 | 1995-12-20 | Universidad De Oviedo | Antibodies against pneumolysine and their applications |
| WO1999003884A2 (en) * | 1997-07-21 | 1999-01-28 | North American Vaccine, Inc. | Modified immunogenic pneumolysin, compositions and their use as vaccines |
| US6342224B1 (en) * | 1997-08-22 | 2002-01-29 | Smithkline Beecham Biologicals, S.A. | Recombinant papillomavirus vaccine and method for production and treatment |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MC2178A1 (fr) * | 1988-12-16 | 1992-05-22 | Nederlanden Staat | Mutants de la pneumolysine et vaccins a base de pneumocoque prepares a partir de ces mutants |
| US5565204A (en) * | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
| EP1100921B1 (en) * | 1998-07-27 | 2007-05-02 | Sanofi Pasteur Limited | Streptococcus pneumoniae proteins and nucleic acid molecules |
| AU772356B2 (en) * | 1998-12-04 | 2004-04-22 | Aventis Pasteur Limited | Two-step immunization procedure against chlamydia infection |
| EP2206785A1 (en) * | 1998-12-31 | 2010-07-14 | Novartis Vaccines and Diagnostics, Inc. | Improved expression of HIV polypeptides and production of virus-like particles |
| DE60026588T2 (de) * | 1999-12-17 | 2007-01-18 | Wyeth Holdings Corp. | Impfstoffe zur erhöhung der immunantworten gegen herpes simplex virus |
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2003
- 2003-11-06 CA CA2504938A patent/CA2504938C/en not_active Expired - Lifetime
- 2003-11-06 ES ES03768757.1T patent/ES2451620T3/es not_active Expired - Lifetime
- 2003-11-06 WO PCT/US2003/035529 patent/WO2004043376A2/en not_active Ceased
- 2003-11-06 CN CNB2003801027586A patent/CN100443116C/zh not_active Expired - Lifetime
- 2003-11-06 US US10/702,305 patent/US7217791B2/en not_active Expired - Lifetime
- 2003-11-06 KR KR1020057008095A patent/KR20050086427A/ko not_active Ceased
- 2003-11-06 AU AU2003291365A patent/AU2003291365B2/en not_active Expired
- 2003-11-06 EP EP03768757.1A patent/EP1558280B1/en not_active Expired - Lifetime
- 2003-11-06 JP JP2004551863A patent/JP2006506989A/ja active Pending
- 2003-11-06 TW TW092131025A patent/TWI315986B/zh not_active IP Right Cessation
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2007
- 2007-05-14 US US11/748,270 patent/US7585669B2/en not_active Expired - Lifetime
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2009
- 2009-11-04 JP JP2009253536A patent/JP2010057501A/ja active Pending
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2012
- 2012-02-08 JP JP2012025451A patent/JP2012139221A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0687688A1 (en) * | 1993-12-17 | 1995-12-20 | Universidad De Oviedo | Antibodies against pneumolysine and their applications |
| WO1999003884A2 (en) * | 1997-07-21 | 1999-01-28 | North American Vaccine, Inc. | Modified immunogenic pneumolysin, compositions and their use as vaccines |
| US6342224B1 (en) * | 1997-08-22 | 2002-01-29 | Smithkline Beecham Biologicals, S.A. | Recombinant papillomavirus vaccine and method for production and treatment |
Non-Patent Citations (1)
| Title |
|---|
| (X) McDaniel et. al. Gene Therapy 4(4):375-7 (1997) * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1558280A2 (en) | 2005-08-03 |
| JP2012139221A (ja) | 2012-07-26 |
| AU2003291365A1 (en) | 2004-06-03 |
| KR20050086427A (ko) | 2005-08-30 |
| WO2004043376A2 (en) | 2004-05-27 |
| CN1711105A (zh) | 2005-12-21 |
| CN100443116C (zh) | 2008-12-17 |
| CA2504938C (en) | 2011-10-11 |
| US20080199952A1 (en) | 2008-08-21 |
| JP2006506989A (ja) | 2006-03-02 |
| US7585669B2 (en) | 2009-09-08 |
| TW200418502A (en) | 2004-10-01 |
| EP1558280B1 (en) | 2014-01-08 |
| WO2004043376A3 (en) | 2004-10-14 |
| TWI315986B (en) | 2009-10-21 |
| HK1074005A1 (en) | 2005-10-28 |
| CA2504938A1 (en) | 2004-05-27 |
| US7217791B2 (en) | 2007-05-15 |
| ES2451620T3 (es) | 2014-03-28 |
| JP2010057501A (ja) | 2010-03-18 |
| EP1558280A4 (en) | 2007-08-29 |
| US20040213803A1 (en) | 2004-10-28 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |