AU2003287077B2 - Methylene-bridged selective androgen receptor modulators and methods of use thereof - Google Patents
Methylene-bridged selective androgen receptor modulators and methods of use thereof Download PDFInfo
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- AU2003287077B2 AU2003287077B2 AU2003287077A AU2003287077A AU2003287077B2 AU 2003287077 B2 AU2003287077 B2 AU 2003287077B2 AU 2003287077 A AU2003287077 A AU 2003287077A AU 2003287077 A AU2003287077 A AU 2003287077A AU 2003287077 B2 AU2003287077 B2 AU 2003287077B2
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- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
Landscapes
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- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41816602P | 2002-10-15 | 2002-10-15 | |
| US60/418,166 | 2002-10-15 | ||
| PCT/US2003/032511 WO2004035738A2 (en) | 2002-10-15 | 2003-10-14 | Methylene-bridged selective androgen receptor modulators and methods of use thereof |
Publications (2)
| Publication Number | Publication Date |
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| AU2003287077A1 AU2003287077A1 (en) | 2004-05-04 |
| AU2003287077B2 true AU2003287077B2 (en) | 2007-09-20 |
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| AU2003287077A Ceased AU2003287077B2 (en) | 2002-10-15 | 2003-10-14 | Methylene-bridged selective androgen receptor modulators and methods of use thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7253210B2 (https=) |
| EP (1) | EP1562594A4 (https=) |
| JP (1) | JP2006506369A (https=) |
| CN (1) | CN1726034A (https=) |
| AU (1) | AU2003287077B2 (https=) |
| CA (1) | CA2502209A1 (https=) |
| TW (1) | TW200503711A (https=) |
| WO (1) | WO2004035738A2 (https=) |
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| US7855229B2 (en) | 2000-08-24 | 2010-12-21 | University Of Tennessee Research Foundation | Treating wasting disorders with selective androgen receptor modulators |
| US8445534B2 (en) | 2000-08-24 | 2013-05-21 | University Of Tennessee Research Foundation | Treating androgen decline in aging male (ADAM)-associated conditions with SARMs |
| US7622503B2 (en) | 2000-08-24 | 2009-11-24 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
| US7919647B2 (en) | 2000-08-24 | 2011-04-05 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and methods of use thereof |
| US7645898B2 (en) | 2000-08-24 | 2010-01-12 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and method of use thereof |
| AU2006200749A1 (en) * | 2000-08-24 | 2006-03-16 | University Of Tennessee Research Foundation | Halogenated selective androgen receptor modulators and methods of use thereof |
| US8853266B2 (en) | 2001-12-06 | 2014-10-07 | University Of Tennessee Research Foundation | Selective androgen receptor modulators for treating diabetes |
| AU2003287075A1 (en) * | 2002-10-15 | 2004-05-04 | Gtx, Inc. | Treating obesity with selective androgen receptor modulators |
| JP2006516286A (ja) * | 2003-01-22 | 2006-06-29 | ジーティーエックス・インコーポレイテッド | Ｓａｒｍによる女性のアンドロゲン減少に関連する病気の治療 |
| US9884038B2 (en) | 2004-06-07 | 2018-02-06 | University Of Tennessee Research Foundation | Selective androgen receptor modulator and methods of use thereof |
| US9889110B2 (en) | 2004-06-07 | 2018-02-13 | University Of Tennessee Research Foundation | Selective androgen receptor modulator for treating hormone-related conditions |
| US9492400B2 (en) | 2004-11-04 | 2016-11-15 | Massachusetts Institute Of Technology | Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals |
| CN101146535A (zh) * | 2005-03-25 | 2008-03-19 | 默克公司 | 用睾酮补充剂和5α-还原酶抑制剂治疗男性病人的方法 |
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- 2003-10-14 CN CNA2003801061426A patent/CN1726034A/zh active Pending
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- 2003-10-14 JP JP2004544890A patent/JP2006506369A/ja active Pending
- 2003-10-14 EP EP03777598A patent/EP1562594A4/en not_active Withdrawn
- 2003-10-15 TW TW092128551A patent/TW200503711A/zh unknown
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| US20080319009A1 (en) | 2008-12-25 |
| WO2004035738A3 (en) | 2004-07-15 |
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| US7253210B2 (en) | 2007-08-07 |
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| EP1562594A4 (en) | 2008-12-17 |
| US20040147550A1 (en) | 2004-07-29 |
| WO2004035738A2 (en) | 2004-04-29 |
| JP2006506369A (ja) | 2006-02-23 |
| TW200503711A (en) | 2005-02-01 |
| CN1726034A (zh) | 2006-01-25 |
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