AU2003260306A1 - Bicyclic oligopeptides - Google Patents
Bicyclic oligopeptidesInfo
- Publication number
- AU2003260306A1 AU2003260306A1 AU2003260306A AU2003260306A AU2003260306A1 AU 2003260306 A1 AU2003260306 A1 AU 2003260306A1 AU 2003260306 A AU2003260306 A AU 2003260306A AU 2003260306 A AU2003260306 A AU 2003260306A AU 2003260306 A1 AU2003260306 A1 AU 2003260306A1
- Authority
- AU
- Australia
- Prior art keywords
- group
- amino acid
- cysteine
- bicyclic
- cyclic group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 102000015636 Oligopeptides Human genes 0.000 title abstract 3
- 108010038807 Oligopeptides Proteins 0.000 title abstract 3
- 125000002619 bicyclic group Chemical group 0.000 title abstract 3
- 235000001014 amino acid Nutrition 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 125000004122 cyclic group Chemical group 0.000 abstract 3
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 3
- 108010063919 Glucagon Receptors Proteins 0.000 abstract 2
- 102100040890 Glucagon receptor Human genes 0.000 abstract 2
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 150000007942 carboxylates Chemical group 0.000 abstract 1
- 235000018417 cysteine Nutrition 0.000 abstract 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 1
- 230000006806 disease prevention Effects 0.000 abstract 1
- 230000006334 disulfide bridging Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02015907 | 2002-07-17 | ||
| EP02015907.5 | 2002-07-17 | ||
| PCT/EP2003/007311 WO2004007524A2 (en) | 2002-07-17 | 2003-07-08 | Bicyclic oligopeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2003260306A1 true AU2003260306A1 (en) | 2004-02-02 |
Family
ID=30011078
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003260306A Abandoned AU2003260306A1 (en) | 2002-07-17 | 2003-07-08 | Bicyclic oligopeptides |
| AU2003246702A Abandoned AU2003246702A1 (en) | 2002-07-17 | 2003-07-15 | Bicyclic oligopeptides and their use as glucagon receptor antagonists |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003246702A Abandoned AU2003246702A1 (en) | 2002-07-17 | 2003-07-15 | Bicyclic oligopeptides and their use as glucagon receptor antagonists |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1525218B1 (enExample) |
| JP (1) | JP4616000B2 (enExample) |
| AT (1) | ATE415415T1 (enExample) |
| AU (2) | AU2003260306A1 (enExample) |
| CA (1) | CA2489189A1 (enExample) |
| DE (1) | DE60324936D1 (enExample) |
| ES (1) | ES2316820T3 (enExample) |
| WO (2) | WO2004007524A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0917072D0 (en) | 2009-09-29 | 2009-11-11 | Univ Ulster | Peptide analogues of glucagon for diabetes therapy |
| JP2016510306A (ja) * | 2012-05-08 | 2016-04-07 | セリックスビオ プライヴェート リミテッド | 高血糖の治療のための組成物及び方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4139526A (en) * | 1977-12-01 | 1979-02-13 | Merck & Co., Inc. | Somatostatin analogs |
-
2003
- 2003-07-08 WO PCT/EP2003/007311 patent/WO2004007524A2/en not_active Ceased
- 2003-07-08 AU AU2003260306A patent/AU2003260306A1/en not_active Abandoned
- 2003-07-15 AU AU2003246702A patent/AU2003246702A1/en not_active Abandoned
- 2003-07-15 WO PCT/EP2003/007657 patent/WO2004007535A1/en not_active Ceased
- 2003-07-15 AT AT03763864T patent/ATE415415T1/de active
- 2003-07-15 CA CA002489189A patent/CA2489189A1/en not_active Abandoned
- 2003-07-15 ES ES03763864T patent/ES2316820T3/es not_active Expired - Lifetime
- 2003-07-15 DE DE60324936T patent/DE60324936D1/de not_active Expired - Lifetime
- 2003-07-15 JP JP2004520641A patent/JP4616000B2/ja not_active Expired - Fee Related
- 2003-07-15 EP EP03763864A patent/EP1525218B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006505507A (ja) | 2006-02-16 |
| JP4616000B2 (ja) | 2011-01-19 |
| DE60324936D1 (de) | 2009-01-08 |
| EP1525218A1 (en) | 2005-04-27 |
| AU2003246702A1 (en) | 2004-02-02 |
| WO2004007524A2 (en) | 2004-01-22 |
| ATE415415T1 (de) | 2008-12-15 |
| WO2004007535A1 (en) | 2004-01-22 |
| ES2316820T3 (es) | 2009-04-16 |
| EP1525218B1 (en) | 2008-11-26 |
| CA2489189A1 (en) | 2004-01-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |