AU2003229028B2 - A direct cellular energy delivery system - Google Patents

A direct cellular energy delivery system Download PDF

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Publication number
AU2003229028B2
AU2003229028B2 AU2003229028A AU2003229028A AU2003229028B2 AU 2003229028 B2 AU2003229028 B2 AU 2003229028B2 AU 2003229028 A AU2003229028 A AU 2003229028A AU 2003229028 A AU2003229028 A AU 2003229028A AU 2003229028 B2 AU2003229028 B2 AU 2003229028B2
Authority
AU
Australia
Prior art keywords
vesicle
atp
group
formula
phospholipid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2003229028A
Other languages
English (en)
Other versions
AU2003229028A1 (en
Inventor
Sufan Chien
William D. Ehringer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Louisville Research Foundation ULRF
Original Assignee
University of Louisville Research Foundation ULRF
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Louisville Research Foundation ULRF filed Critical University of Louisville Research Foundation ULRF
Publication of AU2003229028A1 publication Critical patent/AU2003229028A1/en
Application granted granted Critical
Publication of AU2003229028B2 publication Critical patent/AU2003229028B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU2003229028A 2002-05-14 2003-05-09 A direct cellular energy delivery system Ceased AU2003229028B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US38076202P 2002-05-14 2002-05-14
US60/380,762 2002-05-14
US10/397,048 2003-03-25
US10/397,048 US7056529B2 (en) 2002-05-14 2003-03-25 Direct cellular energy delivery system
PCT/US2003/014865 WO2003096973A2 (en) 2002-05-14 2003-05-09 A direct cellular energy delivery system

Publications (2)

Publication Number Publication Date
AU2003229028A1 AU2003229028A1 (en) 2003-12-02
AU2003229028B2 true AU2003229028B2 (en) 2008-12-18

Family

ID=29553511

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003229028A Ceased AU2003229028B2 (en) 2002-05-14 2003-05-09 A direct cellular energy delivery system

Country Status (9)

Country Link
US (2) US7056529B2 (enExample)
EP (1) EP1503735A4 (enExample)
JP (1) JP2005525424A (enExample)
KR (1) KR20050003453A (enExample)
CN (1) CN1665488B (enExample)
AU (1) AU2003229028B2 (enExample)
CA (1) CA2485463A1 (enExample)
NZ (1) NZ537163A (enExample)
WO (1) WO2003096973A2 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706474B1 (en) * 2000-06-27 2004-03-16 Board Of Trustees Of The University Of Illinois Nucleic acid enzyme biosensors for ions
US7629329B2 (en) * 2001-06-04 2009-12-08 Tsi Health Sciences, Inc. Method for increasing muscle mass and strength through administration of adenosine triphosphate
US6890719B2 (en) 2002-05-10 2005-05-10 The Board Of Trustess Of The University Of Illinois Fluorescence based biosensor
US20060193905A1 (en) * 2002-05-14 2006-08-31 University Of Louisville Research Foundation, Inc. Direct cellular energy delivery system
US8062891B2 (en) 2003-10-24 2011-11-22 Gencia Corporation Nonviral vectors for delivering polynucleotides to plants
JP4838722B2 (ja) 2003-10-24 2011-12-14 ゲンシア コーポレーション ポリヌクレオチドを送達する方法、及び送達用組成物
US8133733B2 (en) 2003-10-24 2012-03-13 Gencia Corporation Nonviral vectors for delivering polynucleotides to target tissues
US20090208478A1 (en) * 2003-10-24 2009-08-20 Gencia Corporation Transducible polypeptides for modifying metabolism
US8507277B2 (en) 2003-10-24 2013-08-13 Gencia Corporation Nonviral vectors for delivering polynucleotides
US20090123468A1 (en) 2003-10-24 2009-05-14 Gencia Corporation Transducible polypeptides for modifying metabolism
US20060045910A1 (en) * 2004-09-02 2006-03-02 Ehringer William D Preserved fusogenic vesicles
BRPI0613185A2 (pt) * 2005-04-29 2010-12-21 Univ Louisville Res Found revestimento de superfìcie celular com agentes ativos
US7892734B2 (en) * 2005-08-11 2011-02-22 The Board Of Trustees Of The University Of Illinois Aptamer based colorimetric sensor systems
WO2007109500A1 (en) * 2006-03-16 2007-09-27 The Board Of Trustees Of The University Of Illinois Lateral flow devices
US8415461B2 (en) * 2007-01-19 2013-04-09 The Board Of Trustees Of The University Of Illinois Amphiphilic substances and functionalized lipid vesicles including the same
US8058415B2 (en) * 2007-04-24 2011-11-15 The Board Of Trustees Of The University Of Illinois Aptamer- and nucleic acid enzyme-based systems for simultaneous detection of multiple analytes
CA2688240A1 (en) 2007-05-24 2008-12-04 The United States Government As Represented By The Department Of Veterans Affairs Intranuclear protein transduction through a nucleoside salvage pathway
WO2009012309A2 (en) * 2007-07-16 2009-01-22 The Board Of Trustees Of The University Of Illinois Nucleic acid based fluorescent sensor for divalent copper ion detection
US8568690B2 (en) * 2007-07-31 2013-10-29 The Board Of Trustees Of The University Of Illinois MRI contrast agents and high-throughput screening by MRI
WO2009045632A2 (en) 2007-08-10 2009-04-09 The Board Of Trustees Of The University Of Illinois Nucleic acid based fluorescent sensor for mercury detection
US20100105039A1 (en) * 2008-06-03 2010-04-29 Yi Lu Label-free colorimetric detection
US8062893B2 (en) 2008-10-10 2011-11-22 The Board Of Trustees Of The University Of Illinois Fluorescent sensor for mercury
US8527209B2 (en) 2010-06-24 2013-09-03 The Invention Science Fund I, Llc Rejuvenation or preservation of germ cells
US8815156B2 (en) 2010-07-19 2014-08-26 Andalyze, Inc. Sensor housing and reagent chemistry
US10279007B2 (en) 2010-11-15 2019-05-07 Oxygenetix Institute, Inc. Topical treatment method for healing wounds, disinfecting, covering and concealing the wound until healing occurs
CN103076412B (zh) * 2013-01-11 2014-08-13 南京大学 非放射性判别膜蛋白质转运功能的方法
US9987375B2 (en) * 2013-09-23 2018-06-05 Amirhossein Sahebkar Method and composition for treatment of dyslipidemia and other diseases
FR3033697B1 (fr) 2015-03-17 2020-03-27 Universite Pierre Et Marie Curie (Paris 6) Suspensions de collagene injectables, leur procede de preparation et leurs utilisations, notamment pour la formation de matrices denses de collagene
WO2018089495A1 (en) * 2016-11-08 2018-05-17 University Of Louisville Research Foundation, Inc. Encapsulation of phosphodiesterase inhibitors to treat alcoholic liver disease
EP3946368A4 (en) * 2019-04-03 2022-12-28 New York University ADENOSIN-ENCAPSULATING LIPOSOMES
WO2025133317A1 (en) 2023-12-22 2025-06-26 Idea Stem Cell, S.L. Composition for promoting hair growth

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674528A (en) * 1994-06-15 1997-10-07 Terumo Kabushiki Kaisha Hemoglobin-encapsulated liposome

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5820848A (en) 1990-01-12 1998-10-13 The Liposome Company, Inc. Methods of preparing interdigitation-fusion liposomes and gels which encapsulate a bioactive agent
JP2844103B2 (ja) 1990-02-09 1999-01-06 株式会社コーセー 皮膚外用剤
US6011020A (en) 1990-06-11 2000-01-04 Nexstar Pharmaceuticals, Inc. Nucleic acid ligand complexes
US5088851A (en) * 1990-10-01 1992-02-18 Gerhard Hutter Dowel fastening device
US5863556A (en) * 1993-08-20 1999-01-26 Euro-Celtique, S.A. Preparations for the external application of antiseptic agents and/or agents promoting the healing of wounds
US5540935A (en) * 1993-12-06 1996-07-30 Nof Corporation Reactive vesicle and functional substance-fixed vesicle
DE4416180C2 (de) * 1994-05-06 1997-08-14 Immuno Ag Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen und Verfahren zur Herstellung dieses Präparats
CA2252055C (en) * 1996-04-11 2007-01-16 The University Of British Columbia Fusogenic liposomes
JP2000516641A (ja) * 1997-07-02 2000-12-12 エスディージー インコーポレイテッド 診断および治療用途の目標指向性リポソーム構成物
DE19925519A1 (de) * 1999-06-04 2000-12-07 Lohmann Therapie Syst Lts Wundauflage zur gesteuerten Abgabe von Wirkstoff an Wunden und Verfahren zu ihrer Herstellung

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5674528A (en) * 1994-06-15 1997-10-07 Terumo Kabushiki Kaisha Hemoglobin-encapsulated liposome

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Chemical abstracts (1988), vol. 109, page 11, abstract 85657m *
Pharm. Res. (1990), vol.7, no.5, pages 553-557 *

Also Published As

Publication number Publication date
CA2485463A1 (en) 2003-11-27
JP2005525424A (ja) 2005-08-25
WO2003096973A2 (en) 2003-11-27
CN1665488A (zh) 2005-09-07
US7056529B2 (en) 2006-06-06
US7041312B2 (en) 2006-05-09
EP1503735A2 (en) 2005-02-09
EP1503735A4 (en) 2011-01-12
CN1665488B (zh) 2011-04-13
NZ537163A (en) 2007-01-26
US20030235611A1 (en) 2003-12-25
KR20050003453A (ko) 2005-01-10
AU2003229028A1 (en) 2003-12-02
WO2003096973A3 (en) 2004-02-26
US20040137051A1 (en) 2004-07-15

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DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: ADD THE CO-INVENTOR CHIEN, SUFAN

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired