AU2002318759A1 - Remedies for diseases with bone mass loss having EP4 agonists as the active ingredient - Google Patents
Remedies for diseases with bone mass loss having EP4 agonists as the active ingredientInfo
- Publication number
- AU2002318759A1 AU2002318759A1 AU2002318759A AU2002318759A AU2002318759A1 AU 2002318759 A1 AU2002318759 A1 AU 2002318759A1 AU 2002318759 A AU2002318759 A AU 2002318759A AU 2002318759 A AU2002318759 A AU 2002318759A AU 2002318759 A1 AU2002318759 A1 AU 2002318759A1
- Authority
- AU
- Australia
- Prior art keywords
- remedies
- agonists
- diseases
- active ingredient
- bone mass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000000988 Bone and Bones Anatomy 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001-222148 | 2001-07-23 | ||
JP2001222148 | 2001-07-23 | ||
JP2001-239895 | 2001-08-07 | ||
JP2001239895 | 2001-08-07 | ||
JP2002056449 | 2002-03-01 | ||
JP2002-56449 | 2002-03-01 | ||
PCT/JP2002/007385 WO2003009872A1 (en) | 2001-07-23 | 2002-07-22 | Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
Publications (3)
Publication Number | Publication Date |
---|---|
AU2002318759A1 true AU2002318759A1 (en) | 2003-05-29 |
AU2002318759B2 AU2002318759B2 (en) | 2007-09-13 |
AU2002318759C1 AU2002318759C1 (en) | 2009-03-05 |
Family
ID=27347210
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2002318759A Ceased AU2002318759C1 (en) | 2001-07-23 | 2002-07-22 | Remedies for diseases with bone mass loss having EP4 agonists as the active ingredient |
Country Status (22)
Country | Link |
---|---|
US (3) | US7608637B2 (en) |
EP (2) | EP1417975B1 (en) |
JP (3) | JP4273407B2 (en) |
KR (3) | KR20070043059A (en) |
CN (1) | CN101921220B (en) |
AT (1) | ATE500218T1 (en) |
AU (1) | AU2002318759C1 (en) |
BR (1) | BR0211364A (en) |
CA (1) | CA2454584C (en) |
DE (1) | DE60239343D1 (en) |
DK (1) | DK1417975T3 (en) |
HU (1) | HU230421B1 (en) |
IL (1) | IL159996A0 (en) |
MX (1) | MXPA04000757A (en) |
NO (2) | NO332625B1 (en) |
NZ (1) | NZ530885A (en) |
PL (1) | PL367740A1 (en) |
PT (1) | PT1417975E (en) |
RU (1) | RU2303451C2 (en) |
TW (1) | TWI313608B (en) |
WO (1) | WO2003009872A1 (en) |
ZA (1) | ZA200400493B (en) |
Families Citing this family (57)
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US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
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IL159996A0 (en) * | 2001-07-23 | 2004-06-20 | Ono Pharmaceutical Co | Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
WO2003047417A2 (en) * | 2001-12-03 | 2003-06-12 | Merck & Co., Inc. | Ep4 receptor agonist, compositions and methods thereof |
RU2306309C2 (en) * | 2002-03-05 | 2007-09-20 | Оно Фармасьютикал Ко., Лтд. | 8-azaprostaglandine derivatives, pharmaceutical composition and agent for prophylaxis of diseases |
US6573294B1 (en) | 2002-05-14 | 2003-06-03 | Allergan, Inc. | 8-azaprostaglandin analogs as agents for lowering intraocular pressure |
CA2487977A1 (en) * | 2002-06-06 | 2003-12-18 | Merck Frosst Canada & Co./Merck Frosst Canada & Cie | 1,5-disubstituted imidazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of eye and bone diseases |
JP4754820B2 (en) * | 2002-06-10 | 2011-08-24 | メルク セローノ ソシエテ アノニム | Gamma lactams and their use as prostaglandin agonists |
JP2006504679A (en) * | 2002-08-28 | 2006-02-09 | メルク フロスト カナダ アンド カンパニー | Oxazolidin-2-one and thiazolidine-2-one derivatives for use as EP4 receptor agonists in the treatment of glaucoma |
AU2003275838A1 (en) * | 2002-10-25 | 2004-05-13 | Beunard, Jean-Luc | Pyrrolidin-2-on derivatives as ep4 receptor agonists |
CA2502914A1 (en) * | 2002-10-25 | 2004-05-06 | Merck Frosst Canada & Co. | 2-pyrrolidones as ep4 receptor agonists |
EP1586564B1 (en) * | 2003-01-21 | 2012-11-28 | Ono Pharmaceutical Co., Ltd. | 8-azaprostaglandin derivatives and medicinal uses thereof |
US6734206B1 (en) | 2003-06-02 | 2004-05-11 | Allergan, Inc. | 3-oxa-8-azaprostaglandin analogs as agents for lowering intraocular pressure |
US6734201B1 (en) * | 2003-06-02 | 2004-05-11 | Allergan, Inc. | 8-Azaprostaglandin carbonate and thiocarbonate analogs as therapeutic agents |
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JP4893999B2 (en) | 2004-10-22 | 2012-03-07 | 小野薬品工業株式会社 | Pharmaceutical composition for inhalation |
US20080132543A1 (en) * | 2004-10-26 | 2008-06-05 | Wha Bin Im | Therapeutic and Delivery Methods of Prostaglandin Ep4, Agonists |
US7547685B2 (en) | 2004-11-08 | 2009-06-16 | Allergan, Inc. | Therapeutic substituted pyrrolidone compounds |
CA2587318A1 (en) | 2004-12-06 | 2006-06-15 | Laboratoires Serono S.A. | Pyrrolidin-2-one derivatives for use as dp1 receptor agonists |
JPWO2006118173A1 (en) | 2005-04-28 | 2008-12-18 | 小野薬品工業株式会社 | Transdermal absorption preparation |
KR101320810B1 (en) * | 2005-06-03 | 2013-10-21 | 오노 야꾸힝 고교 가부시키가이샤 | Agent for regeneration and/or protection of nerves |
US7893107B2 (en) * | 2005-11-30 | 2011-02-22 | Allergan, Inc. | Therapeutic methods using prostaglandin EP4 agonist components |
US7491844B2 (en) * | 2006-05-04 | 2009-02-17 | Allergan, Inc. | Therapeutic cyclopentane derivatives |
US7476755B2 (en) * | 2006-05-04 | 2009-01-13 | Allergan, Inc. | Therapeutic compounds |
US8410171B2 (en) * | 2006-10-26 | 2013-04-02 | Ono Pharmaceutical Co., Ltd. | Adhesive preparation |
WO2008058766A1 (en) | 2006-11-16 | 2008-05-22 | Bayer Schering Pharma Aktiengesellschaft | Ep2 and ep4 agonists as agents for the treatment of influenza a viral infection |
MX2009012043A (en) | 2007-05-08 | 2010-02-18 | Nat Univ Corp Hamamatsu | Cytotoxic t cell activator comprising ep4 agonist. |
EP2149552A1 (en) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | 5,6 substituted benzamide derivatives as modulators of EP2 receptors |
EP2149554A1 (en) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma Aktiengesellschaft | Indolyamides as modulators for an EP2 receptor |
EP2149551A1 (en) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors |
JP5557216B2 (en) * | 2009-03-13 | 2014-07-23 | 国立大学法人 東京大学 | Polyfunctional compound, heteroatom polymer obtained using the same, and production method thereof |
ES2444500T3 (en) | 2009-06-10 | 2014-02-25 | Ono Pharmaceutical Co., Ltd. | Compound that has a detrusor muscle contraction activity and a urethral sphincter muscle relaxation activity |
EP2488168A1 (en) | 2009-10-14 | 2012-08-22 | Gemmus Pharma Inc. | Combination therapy treatment for viral infections |
KR200457847Y1 (en) * | 2010-02-12 | 2012-01-06 | 김인주 | A cable arrenge bend |
AR082428A1 (en) * | 2010-07-30 | 2012-12-05 | Allergan Inc | USE OF AN EP4 AGONIST COMPOUND TO PREPARE A USEFUL PHARMACEUTICAL COMPOSITION TO TREAT IMPERFECTION OF SKIN AND METHODS TO REPAIR RELATED SKIN |
US8697057B2 (en) | 2010-08-19 | 2014-04-15 | Allergan, Inc. | Compositions and soft tissue replacement methods |
US20120142684A1 (en) * | 2010-12-02 | 2012-06-07 | Allergan, Inc. | Compounds and methods for skin repair |
BR112013021035A2 (en) | 2011-02-17 | 2016-10-11 | Allergan Inc | improved soft tissue replacement compositions and methods |
EP2678022A2 (en) | 2011-02-23 | 2014-01-01 | Allergan, Inc. | Compositions and improved soft tissue replacement methods |
MX2014000971A (en) | 2011-08-02 | 2014-02-27 | Ono Pharmaceutical Co | Left ventricular diastolic function improving agent. |
EP2814527A1 (en) | 2012-02-16 | 2014-12-24 | Allergan, Inc. | Compositions and improved soft tissue replacement methods |
WO2013123274A1 (en) | 2012-02-16 | 2013-08-22 | Allergan, Inc. | Compositions and improved soft tissue replacement methods |
EP2814510A1 (en) | 2012-02-16 | 2014-12-24 | Allergan, Inc. | Compositions and improved soft tissue replacement methods |
WO2013123270A1 (en) | 2012-02-16 | 2013-08-22 | Allergan, Inc. | Compositions and improved soft tissue replacement methods |
WO2014015246A1 (en) | 2012-07-19 | 2014-01-23 | Cayman Chemical Company, Inc. | Difluorolactam compositions for ep4-mediated osteo related diseases and conditions |
RU2503458C1 (en) * | 2012-08-27 | 2014-01-10 | Сергей Васильевич Чуйкин | Method of local treatment and prevention of primary dental diseases in children with chronic renal pathology using chewable phytosubstrate |
MY177737A (en) | 2012-08-31 | 2020-09-23 | Ono Pharmaceutical Co | Amine salt and crystals thereof |
US9676712B2 (en) | 2013-03-15 | 2017-06-13 | Cayman Chemical Company, Inc. | Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions |
EP2970234B1 (en) * | 2013-03-15 | 2018-07-18 | Cayman Chemical Company, Inc. | Methods of synthesizing a difluorolactam analog |
EP3235817B1 (en) | 2013-03-15 | 2018-12-12 | Cayman Chemical Company, Incorporated | Lactam compounds as ep4 receptor-selective agonists for use in the treatment of ep4-mediated diseases and conditions |
JP2016527006A (en) * | 2013-07-19 | 2016-09-08 | ケイマン ケミカル カンパニー, インコーポレーテッド | Methods, systems, and compositions for promoting bone growth |
KR102456567B1 (en) | 2013-08-09 | 2022-10-19 | 알데릭스, 인코포레이티드 | Compounds and methods for inhibiting phosphate transport |
ES2929799T3 (en) | 2017-12-25 | 2022-12-01 | Asahi Kasei Pharma Corp | Compounds containing 2-oxo-1,3,4-thiadiazinan-3-yl moiety with EP4 receptor agonist activity |
EP3972599A1 (en) | 2019-05-21 | 2022-03-30 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
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IL49325A (en) | 1976-03-31 | 1979-11-30 | Labaz | 8-aza-11-deoxy-pge1 derivatives,their preparation and pharmaceutical compositions containing them |
DE2619638A1 (en) * | 1976-05-04 | 1977-11-17 | Hoechst Ag | PYRROLIDONE AND THE METHOD FOR MANUFACTURING THEIR |
SE423813B (en) * | 1976-08-06 | 1982-06-07 | Pfizer | PROCEDURE FOR THE PREPARATION OF 1,5-DISUBSTITUTED PYRROLIDONS WITH THERAPEUTICAL PROPERTIES |
US4177346A (en) | 1976-08-06 | 1979-12-04 | Pfizer Inc. | 1,5-Disubstituted-2-pyrrolidones |
US4320136A (en) * | 1980-08-11 | 1982-03-16 | E. I. Du Pont De Nemours And Company | 8-Aza-16,16-difluoroprostanoids |
JPS57156460A (en) | 1981-03-20 | 1982-09-27 | Ono Pharmaceut Co Ltd | Stabilized composition of prostaglandin and prostaglandin mimic compound, and its preparation |
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UA72293C2 (en) | 1999-12-22 | 2005-02-15 | Pfizer Prod Inc | Ep4 receptor selective agonists (variants) for treating conditions presenting with low bone mass and pharmaceutical composition |
ATE327751T1 (en) * | 2000-01-31 | 2006-06-15 | Pfizer Prod Inc | USE OF PROSTAGLAND RECEPTOR 4 ACTIVATORS FOR THE TREATMENT OF ACUTE OR CHRONIC RENAL INSUFFICIENCY |
US20010056060A1 (en) * | 2000-02-07 | 2001-12-27 | Cameron Kimberly O. | Treatment of osteoporsis with EP2/EP4 receptor selective agonists |
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WO2002024647A1 (en) | 2000-09-21 | 2002-03-28 | Ono Pharmaceutical Co., Ltd. | Ep4 receptor agonists containing 8-azaprostaglandin derivatives as the active ingredient |
NZ525164A (en) | 2000-11-27 | 2005-04-29 | Pfizer Prod Inc | EP4 receptor selective agonists in the treatment of osteoporosis |
CA2451393C (en) | 2001-07-16 | 2011-01-04 | F. Hoffmann-La Roche Ag | 2 pyrrolidone derivatives as prostanoid agonists |
IL159996A0 (en) * | 2001-07-23 | 2004-06-20 | Ono Pharmaceutical Co | Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient |
-
2002
- 2002-07-22 IL IL15999602A patent/IL159996A0/en not_active IP Right Cessation
- 2002-07-22 PT PT02747707T patent/PT1417975E/en unknown
- 2002-07-22 CA CA002454584A patent/CA2454584C/en not_active Expired - Fee Related
- 2002-07-22 HU HU0600140A patent/HU230421B1/en not_active IP Right Cessation
- 2002-07-22 BR BR0211364-3A patent/BR0211364A/en active Search and Examination
- 2002-07-22 TW TW091116219A patent/TWI313608B/en not_active IP Right Cessation
- 2002-07-22 US US10/484,500 patent/US7608637B2/en not_active Expired - Fee Related
- 2002-07-22 DK DK02747707.4T patent/DK1417975T3/en active
- 2002-07-22 KR KR1020077007791A patent/KR20070043059A/en not_active Application Discontinuation
- 2002-07-22 AU AU2002318759A patent/AU2002318759C1/en not_active Ceased
- 2002-07-22 EP EP02747707A patent/EP1417975B1/en not_active Expired - Lifetime
- 2002-07-22 KR KR1020077016142A patent/KR20070087078A/en not_active Application Discontinuation
- 2002-07-22 DE DE60239343T patent/DE60239343D1/en not_active Expired - Lifetime
- 2002-07-22 KR KR1020047000997A patent/KR100826866B1/en not_active IP Right Cessation
- 2002-07-22 JP JP2003515264A patent/JP4273407B2/en not_active Expired - Fee Related
- 2002-07-22 MX MXPA04000757A patent/MXPA04000757A/en active IP Right Grant
- 2002-07-22 EP EP10176842A patent/EP2255829A3/en not_active Withdrawn
- 2002-07-22 WO PCT/JP2002/007385 patent/WO2003009872A1/en active Application Filing
- 2002-07-22 PL PL02367740A patent/PL367740A1/en unknown
- 2002-07-22 RU RU2004105154/15A patent/RU2303451C2/en not_active IP Right Cessation
- 2002-07-22 NZ NZ530885A patent/NZ530885A/en not_active IP Right Cessation
- 2002-07-22 CN CN2010102514340A patent/CN101921220B/en not_active Expired - Fee Related
- 2002-07-22 AT AT02747707T patent/ATE500218T1/en active
-
2004
- 2004-01-22 ZA ZA2004/00493A patent/ZA200400493B/en unknown
- 2004-01-23 NO NO20040331A patent/NO332625B1/en not_active IP Right Cessation
-
2008
- 2008-12-25 JP JP2008329756A patent/JP4973650B2/en not_active Expired - Fee Related
-
2009
- 2009-08-27 US US12/549,136 patent/US8207223B2/en not_active Expired - Fee Related
-
2011
- 2011-12-22 NO NO20111765A patent/NO20111765L/en not_active Application Discontinuation
-
2012
- 2012-01-16 JP JP2012006534A patent/JP5387699B2/en not_active Expired - Fee Related
- 2012-04-23 US US13/453,434 patent/US20120202773A1/en not_active Abandoned
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