AU2002318174A1 - Dynamic anterior cervical plate system having moveable segments, instrumentation, and method for installation thereof - Google Patents

Description

DYNAMIC ANTERIOR CERVICAL PLATE SYSTEM HAVING MOVEABLE SEGMENTS, INSTRUMENTATION, AND METHOD FOR INSTALLATION

THEREOF

Related Applications

This application claims the benefit of provisional application no. 60/379,589, filed May 9, 2002; and provisional application no. 60/377,916, filed May 3, 2002; provisional application no. 60/356,318, filed February 12, 2002; provisional application no. 60/355,194, filed February 8, 2002; provisional application no.

60/296,681 , filed June 6, 2001 ; provisional application no. 60/296,680, filed June 6, 2001 ; provisional application no. 60/296,060, filed June 4, 2001 ; provisional application no. 60/296,059, filed June 4, 2001 ; all of which are incorporated by reference herein. BACKGROUND

The use of plates, screws, and locks to prevent separation and backing out of screws from the plate, for use on the anterior aspect of the cervical spine to provide alignment and stability as an adjunct to fusion of adjacent vertebral bodies is known in the art. Also known in the art is that compressive load, within a physiological range across a fusion site, is beneficial to the fusion process. Conversely, a failure to maintain a compressive load across a fusion site, or to have a gap in the fusion construct continuity may lead to a failure to achieve fusion called pseudoarthrosis. A primary purpose of the aforementioned cervical hardware is to provide stability during the healing and fusion process. The fusion process occurs in part through a process called "creeping substitution" by which new living bone replaces the dead bone such as that of a bone graft. The fusion process involves a phase of bone resorption as preliminary to the formation of the new bone. It is possible then for the bone resorption to result in gaps in the continuity of the fusion mass, such that if the hardware is sufficiently rigid, such as occurs as a result of increasing the strength of the components and constraining the relationship of the screws to the plate, those gaps may persist and increase in size as the hardware holds the bone portions separated rather than allowing those bone portions to move together to close those gaps. This holding apart of the bone portions (called distraction) can therefore lead to a failure of fusion (pseudoarthrosis). These rigid systems by a combination of not inducing compression at the fusion site and of holding the bone portions to be fused apart may cause a "distraction pseudoarthrosis."

Alternative cervical plating systems have attempted to prevent distraction pseudoarthrosis by allowing the vertebral bodies to collapse towards each other as needed during the fusion process. Generally this has been done by allowing the bone screws to be free to move relative to the plate, that is, movement such as sliding, swiveling, rotating, and angulating, independent of whether the screws are prevented from separating or backing out of the plates such as by the use of locks. Undesired multidirectional instability can occur in such plating systems that is counter to the very purpose of such hardware which is to increase or provide for stability.

Another approach to solving this problem has been to attach by screws a block to each of the vertebral bodies to be fused and then to allow those blocks to slide up and down on a pair of rods. Each of these constructs have in common that they sacrifice stability, the ability to hold the bones to be fused rigidly in place and prevent undesired motion; for the ability to allow, but not cause the vertebral bodies to collapse.

There exists therefore a need for an improved anterior cervical plating system that is: (1 ) sufficiently rigid to maintain the desired alignment of the vertebral bodies to be fused; (2) capable of inducing compressive load across the fusion site; and/or (3) capable of allowing for the motion of the vertebral bodies towards each other to prevent or to close any gaps in the continuity of the fusion construct, while still being capable of preventing motion in all other directions. When similar challenges have been faced at other skeletal locations, the solution involved anchoring the bone screws through the far cortex of the bone portions to be joined, in effect anchoring the screws in such a way as to make it possible for the screws to force movement of the plates. In the cervical spine anteriorly, however, it has been found to be highly undesirable to drive the bone screws through the far cortex of the vertebral bodies, as this is where the spinal cord is located. There remains therefore a need for an improved cervical plating system as just described that does not require that the bone screws penetrate the far cortex to achieve the desired purpose as described.

The size of the vertebral bodies and the spacing between the vertebral bodies varies from patient to patient. The height of the vertebral bodies and the discs therebetween may vary level by level even in the same person. Thus, a plate of correct length does not necessarily have bone screw receiving holes correctly positioned to overlie the vertebral bodies in accordance with the spacing of the vertebral bodies to which the plate is to be applied. As a result, conventional plating systems of the past had to be manufactured in many different lengths and spacing configurations which were nevertheless fixed in an attempt to provide plates for many, though still possibly not all, of the various sizes and spacings of the vertebral bodies to which the plate was to be applied. For example, in a multi-segment plate the length of the plate would need to correspond to the overall length of the vertebral bodies to be joined and actual distances therebetween and the screw holes of the plate arranged to overlie the vertebral bodies. In order to cover the possible range of sizes, health care facilities would need to carry a large inventory of different sizes of plates, in some cases as many as sixty different sized plates would be needed. Such a large inventory is an expensive undertaking and still worse, facilities with a high caseload need to invest in more than one of each plate size to provide for the possibility of overlapping demand for the same plate size. Facilities with lower caseloads may find it prohibitively expensive to stock an inventory of plates sufficient to cover the range of possible sizes and thus might not be able to afford to stock a set at all or have less than all sizes of plates needed for all cases. Manufactures cannot afford to place a set of plates on consignment in facilities with low caseloads as the number of sales would not cover the carrying costs of the plates.

There exists therefore a need for an improved anterior cervical plating system that (1 ) allows for the overall adjustability of the length of the plate; (2) allows for variations in spacing between the bone screw receiving holes of the plate portions corresponding to the attachment point of the plate to the vertebral bodies; (3) reduces the requisite plate inventory; and (4) can avoid or prevent distraction pseudoarthrosis without itself introducing multidirectional instability. SUMMARY OF THE INVENTION

The present invention in one preferred embodiment is a dynamic anterior cervical plating system including a plate comprising segments in moveable relationship to each other adapted to allow for the overall adjustability of the length of the plate and for variations in the intersegmental spacing of the bone screw receiving holes, to create and/or store a compressive load across a disc space between two adjacent vertebral bodies to be fused, and/or to allow motion of the vertebral bodies toward each other to prevent or close gaps in the continuity of a fusion construct, while preferably preventing motion in all other directions when in use. As used herein, a spinal fusion segment is defined as two vertebral bodies with an intervertebral implant, made of bone or an artificial material, in the disc space therebetween. As used herein, a fusion construct is defined as a spinal fusion segment plus the hardware, such as a plate and screws for example. The present invention in another preferred embodiment is a dynamic, modular, anterior cervical plating system including a plate comprising assembleable segments in moveable relationship to each other adapted to allow for the overall adjustability of the length of the plate and for variations in the intersegmental spacing of the bone screw receiving holes, to create and/or store a compressive load across a disc space between two adjacent vertebral bodies to be fused, and/or to allow motion of the vertebral bodies toward each other to prevent or close gaps in the continuity of a fusion construct, while preferably preventing motion in all other directions when in use.

The ability to permit the movement of adjacent vertebral bodies toward one another is referred to herein as "dynamization." Dynamization may be "passive" allowing the plate to shorten when a shortening force, such as a compressive load is applied. Dynamization may be "active" wherein the plating system stores energy to induce shortening of the fusion construct should the opportunity present. The present invention plating system may passively dynamize, actively dynamize, provide a combination of both, as well as convert and store certain compressive stresses encountered during the healing phase as will be more fully described herein.

The plate segments also can be moved to vary the spacing between the plate segments as well as the overall length of the plate so that the size of the plate may be adjusted to correspond to a range of sizes and spacing of the adjacent vertebral bodies to which the plate is being applied; thereby greatly reducing the inventory of plate sizes needed. The moveable plate segments combine to form the plate. Each plate segment is attached to a vertebral body to be fused by at least one bone screw and preferably a pair of bone screws, which when inserted, are preferably prevented from backing out of the plate by at least one locking element adapted to lock at least two bone screws to the plate. In an alternative embodiment, a locking element is adapted to lock a single bone screw to the plate.

The paths of the bone screws through the plate may be fixed or variable. If the paths are variable, they may be more or less stable depending on how resistant to motion the screws are relative to the plate when the screws are locked to the plate. To the extent that screws are sufficiently stable in relation to the plate to make use of the present inventive teaching, these screw, plate, and lock combinations or variations thereon are also within the broad scope of the present invention. In a preferred embodiment of the present invention, after each of the segments of the plate are attached to a respective one of the vertebral bodies to be fused, the plate is capable of movement from a first or elongated position to a second or shorter position, a process generally referred to as "passive dynamization" - that is the ability of the system to allow the plated spinal segment to shorten in response to unmet compressive loads to allow for the bone portions to be fused to move close together to restore contact. A preferred embodiment of this present invention is capable of allowing for this passive dynamization while preventing undesirable motions along and around all axes other than the motion along the longitudinal axis of the plate.

In another preferred embodiment of the present invention, the plate segments are articulated in such a way that even the one freedom of movement that is along the longitudinal axis of the plate is selectively limited to the desired passive dynamization - that is shortening of the plate construct. This preferred embodiment of the present invention will shorten as required to maintain loaded contact of the bone portions to be fused, and if challenged, resist any forces such as those that would accompany cervical extension that would distract or destabilize the construct by elongating it. A further benefit of this embodiment is its ability to store and impart a compressive load across the fusion site referred to herein as "active dynamization" wherein energy stored in the system shortens the plate construct if conditions permit. This load can be applied by the surgeon at the time of surgery and/or be produced during the healing phase by harnessing the compressive loads such as occur randomly with neck motion. Compressive load within a physiological range has been shown to have a beneficial effect on the healing of bone. The induction of a compressive load across vertebral bodies to be fused, induces bone growth and when bone resorption occurs at the interface of the graft or implant and the vertebral bodies to be joined, those vertebral bodies are urged to move closer together, thus avoiding the formation of a gap therebetween and thereby acting to mitigate against pseudoarthrosis.

Alternatively, various embodiments of the present invention allow the surgeon to induce a desired amount of preload (compressive force) across the fusion site and to permit a desired amount of shortening of the construct - "active dynamization" should the opportunity occur; and yet lock the system to prevent any further shortening as might present a risk of deformity or be otherwise undesirable. Such a system urges the bone portions closer together.

In a preferred embodiment, a pre-load force can be applied to the plate segments such that while the plate segments may undergo no added motion initially, there is a selective force applied to the plate segments and the plate segments are capable of motion in only one direction, such that should resorption occur at one of the fusion interfaces then the plate segments are not only free to move in a direction toward one another, and only in that direction, but are also urged to do so to relieve that preload force. Such a system urges the vertebral bodies together over time as resorption permits. Alternatively, in another embodiment of the plate of the present invention, a desired amount of preload (compressive force) may be induced across the fusion site to permit active dynamization should the opportunity occur, without locking the system such that after active dynamization is exhausted (if exhausted), then the plate will still allow passive dynamization to occur thereafter.

In another embodiment of the present invention, the plate includes a structural feature such as a groove, recess, slot, cam, or pivot, within its physical perimeter to engage a tool to cooperatively move segments of the plate towards each other. These embodiments of the present invention may be adapted to allow for passive, active, or active plus passive dynamization, and when used to store compressive load to allow for or prevent further motion thereafter. In a preferred version of this embodiment, the structural feature contained within the plate for generating the compressive load and/or shortening the plate, may also serve as the locking mechanism to limit the amount of further shortening possible. Various embodiments of the plating system of the present invention provide one or more of the following advantages:

1. The requisite plate inventory is reduced as each plate may cover a range of sizes. The plate of the present invention includes multiple segments which may be of varying sizes wherein the segments are adapted to be assembled so as to be adjustable to provide for the size and spacing apart of the vertebral bodies to which the plate is to be applied. The plate may have its segments moved relative to one another so that the spacing between the plate segments may be adjusted so as to correspond to the actual distances between the vertebral bodies to be fused in a multi-segment construct for a more precise fit. The height of the discs and the vertebral bodies may vary level by level even in the same person. Thus, the ability to adjust the distances between the segments of the plates that correspond to the attachments to those vertebral bodies allows for a more precise fit of the plate to the spine with a reduced inventory of the number of plates required to do so.

2. It is possible to precisely contour each segment separately. 3. The plating system of the present invention reduces the risk that the plate construct will be discovered to be too short or too long after the attachment process has commenced.

4. It is possible to compress and dynamize levels selectively. 5. The fasteners that link the segments can be tightened to lock the segments after they are compressed or, alternatively, can allow for further motion of the plate segments together.

6. The same hardware can provide for passive dynamization or be rigidly fixed depending on the fasteners used to link plate segments. 7. The system can allow for passive dynamization, active dynamization, the combination of passive and active dynamization, or can convert body motion into active dynamization.

BRIEF DESCRIPTION OF THE DRAWINGS Fig. 1 A is an exploded top perspective view of a plate, a fastener, and a locking element in accordance with a preferred embodiment of the present invention. Fig. 1 B is an exploded top perspective view of a plate, a fastener, and a locking element in accordance with another preferred embodiment of the present invention.

Fig. 1C is an exploded top perspective view of a plate, a fastener, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 1 D is an exploded top perspective view of a plate, a fastener, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 2A is an exploded bottom perspective view of the plate, fastener, and locking element of Fig. 1A. Fig. 2B is an exploded bottom perspective view of the plate, fastener, and locking element of Fig. 1B.

Fig. 2C is an exploded bottom perspective view of the plate, fastener, and locking elements of Fig. 1 C.

Fig. 2D is an exploded bottom perspective view of the plate, fastener, and locking elements of Fig. 1 D. Fig. 3A is a top plan view of the plate, fastener, and locking element of Figs. 1A and 1 B.

Fig. 3C is a top plan view of the plate, fastener, and locking elements of Figs. 1 C and 1 D Fig. 4A is a bottom plan view of the plate, fastener, and locking element of

Fig. 1A.

Fig. 4B is a bottom plan view of the plate, fastener, and locking element of Fig. 1 B.

Fig. 4C is a bottom plan view of the plate, fastener, and locking elements of Fig. 1C.

Fig. 4D is a bottom plan view of the plate, fastener, and locking elements of Fig. 1 D.

Fig. 5A is an end view of the plates of Figs. 1 A-1 D.

Fig. 6A is a side elevation view of the plates of Figs. 1 A and 1 B. Fig. 6C is a side elevation view of the plates of Figs. 1C and 1 D.

Fig. 7A is a partial cross sectional view of the plates of Figs. 1A and 1C.

Fig. 7B is a partial cross sectional view of the plates of Figs. 1 B and I D.Fig. 8A is an enlarged fragmentary view of the plates of Figs. 1A and 1C and an alternative embodiment of a fastener in accordance with the present invention. Fig. 8B is an enlarged fragmentary view of the plates of Figs. 1 B and 1 D and an alternative embodiment of a fastener in accordance with the present invention.

Fig. 9A is an enlarged fragmentary cross sectional view of an embodiment of the ratchetings in the upper and lower portions of the plates of Figs. 1A-1D in a first position. Fig. 10A is a fragmentary cross sectional view of Fig. 9A in a second position.

Fig. 11 A is an enlarged fragmentary cross sectional view of a preferred embodiment of the ratchetings in the upper and lower portions of the plates of the present invention in a first position.

Fig. 12A is a fragmentary cross sectional view of Fig. 11A in a second position. Fig. 13A is a top perspective view of the plates and fasteners of Figs. 1A and 1 B and instrumentation for compressing the plates and instrumentation for locking the fasteners in accordance with a preferred embodiment of the present invention.

Fig. 13C is a top perspective view of the plates and fasteners of Figs. 1C and 1 D and instrumentation for compressing the plates and instrumentation for locking the fasteners in accordance with a preferred embodiment of the present invention.

Fig. 14A is a top plan view of the plates and fasteners of Figs. 1A and 1 B in a compressed state with the instrumentation of Fig. 13A shown in cross section engaging the ends of the plate to compress the plate in the direction of the arrows and with the instrumentation engaging the fastener.

Fig. 14C is a top plan view of the plates and fasteners of Figs. 1C and 1 D in a compressed state with the instrumentation of Fig. 13C shown in cross section engaging the ends of the plate to compress the plate in the direction of the arrows and with the instrumentation engaging the fastener. Fig. 15A is a partial cross sectional view along line 15A — 15A of Fig. 14A for the plate of Fig. 1A.

Fig. 15B is a partial cross sectional view along line 15A — 15A of Fig. 14A for the plate of Fig. 1 B.

Fig. 15C is a partial cross sectional view along line 15C — 15C of Fig. 14C for the plate of Fig. 1 C.

Fig. 15D is a partial cross sectional view along line 15C — 15C of Fig. 14C for the plate of Fig. 1 D.

Fig. 16A is a top perspective view of a plate, a fastener, and locking element in accordance with another preferred embodiment of the present invention. Fig. 16C is a top perspective view of a plate, a fastener, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 17A is a top plan view of the plate and fastener of Fig. 16A.

Fig. 17C is a top plan view of the plate, fastener, and locking elements of Fig. 16C. Fig. 18A is a top plan view of the plate of Fig. 16A in an elongated state with fastener. Fig. 18C is a top plan view of the plate of Fig. 16C in an elongated state, fastener, and locking elements.

Fig. 19A is a bottom plan view of the plate and fastener of Fig. 16A.

Fig. 19B is a bottom plan view of another preferred embodiment of the plate and fastener of Fig. 16A.

Fig. 19C is a bottom plan view of the plate and fastener of Fig. 16C.

Fig. 19D is a bottom plan view of another preferred embodiment of the plate and fastener of Fig. 16C.

Fig. 20A is a partial cross sectional view along line 20A — 20A of the plate of Fig. 17A.

Fig. 20B is a partial cross sectional view along line 20A — 20A of Fig. 17A of a plate and fastener in accordance with another preferred embodiment of the present invention.

Fig. 21 A is an exploded top perspective view of the plate, fastener, and locking element of Fig. 16A.

Fig. 21 B is an exploded top perspective view of the plate, fastener, and locking element of Fig. 16A in accordance with another preferred embodiment of the present invention.

Fig. 21 C is an exploded top perspective view of the plate, fastener, and locking elements of Fig. 16C.

Fig. 21 D is an exploded top perspective view of the plate, fastener, and locking elements of Fig. 16C in accordance with another preferred embodiment of the present invention.

Fig. 22A is an exploded bottom perspective view of the plate, fastener, and locking element of Fig. 16A.

Fig. 22B is an exploded bottom perspective view of the plate, fastener, and locking element of Fig. 21 B.

Fig. 22C is an exploded bottom perspective view of the plate, fastener, and locking elements of Fig. 16C. Fig. 22D is an exploded bottom perspective view of the plate, fastener, and locking elements of Fig. 21 D. Fig. 23A is a top plan view of the plate and fastener of Fig. 16A and a partial fragmentary perspective view of an instrument for compressing the plate and securing the fastener in accordance with another preferred embodiment of the present invention. Fig. 23C is a top plan view of the plate, fastener, and locking elements of Fig.

16C and a partial fragmentary perspective view of an instrument for compressing the plate and securing the fastener in accordance with another preferred embodiment of the present invention.

Fig. 24A is an enlarged cross sectional view of the plate of Fig. 16A with the instrument of Fig. 23A engaging the fastener and positioned within the plate.

Fig. 24B is an enlarged cross sectional view of another preferred embodiment of the plate of Fig. 16A with the instrument of Fig. 23A engaging the fastener and positioned within the plate.

Fig. 24C is an enlarged cross sectional view of the plate of Fig. 16C with the instrument of Fig. 23C engaging the fastener and positioned within the plate.

Fig. 24D is an enlarged cross sectional view of another preferred embodiment of the plate of Fig. 16C with the instrument of Fig. 23C engaging the fastener and positioned within the plate.

Fig. 25A is a fragmentary top plan view of one of the plates of Figs. 16A and 16C in an elongated state with the instrument of Figs. 23A and 23C shown in cross section engaging the fastener and positioned within the plate.

Fig. 26A is a fragmentary top plan view of one of the plates of Figs. 16A and 16C in a compressed state with the instrument of Figs. 23A and 23C shown in cross section engaging the fastener and positioned within the plate to rotate the fastener in the direction of the arrow to compress the plate.

Fig. 27A is an exploded top perspective view of a plate, a fastener, and locking element in accordance with another preferred embodiment of the present invention.

Fig. 27B is an exploded top perspective view of a plate, a fastener, and locking element in accordance with another preferred embodiment of the present invention. Fig. 27C is an exploded top perspective view of a plate, a fastener, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 27D is an exploded top perspective view of a plate, a fastener, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 28A is a cross sectional view transverse to the longitudinal axis of the plate of Figs. 27A-27D.

Fig. 29A is a top plan view of a plate, fasteners, and locking element in accordance with another preferred embodiment of the present invention.

Fig. 29C is a top plan view of a plate, fasteners, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 30A is an exploded top perspective view of the plate, fasteners, and locking element of Fig. 29A. Fig. 30B is an exploded top perspective view of another preferred embodiment of the plate, fasteners, and locking element of Fig. 29A.

Fig. 30C is an exploded top perspective view of the plate, fasteners, and locking elements of Fig. 29C.

Fig. 30D is an exploded top perspective view of another preferred embodiment of the plate, fasteners, and locking elements of Fig. 29C.

Fig. 31 A is an exploded bottom perspective view of the plate, fasteners, and locking element of Fig. 30A.

Fig. 31 B is an exploded bottom perspective view of the plate, fasteners, and locking element of Fig. 30B. Fig. 31 C is an exploded bottom perspective view of the plate, fasteners, and locking elements of Fig. 30C.

Fig. 31 D is an exploded bottom perspective view of the plate, fasteners, and locking elements of Fig. 30D.

Fig. 32A is a top plan view of the plates, fasteners, and locking element of Figs. 30A and 30B. Fig. 32C is a top plan view of the plates, fasteners, and locking elements of Figs. 30C and 30D.

Fig. 33A is a bottom plan view of the plate and fasteners of Fig. 30A.

Fig. 33B is a bottom plan view of the plate and fasteners of Fig. 30B. Fig. 33C is a bottom plan view of the plate, fasteners, and locking elements of

Fig. 30C.

Fig. 33D is a bottom plan view of the plate, fasteners, and locking elements of Fig. 30D.

Fig. 34A is a side elevation view of the plates of Figs. 30A and 30B. Fig. 34C is a side elevation view of the plates of Figs. 30C and 30D.

Fig. 35A is a partial cross sectional view along the longitudinal axis of the plate of Fig. 30A.

Fig. 35B is a partial cross sectional view along the longitudinal axis of the plate of Fig. 30B. Fig. 35C is a partial cross sectional view along the longitudinal axis of the plate of Fig. 30C.

Fig. 35D is a partial cross sectional view along the longitudinal axis of the plate of Fig. 30D.

Fig. 36A is a top plan view of the plates in an elongated position, fasteners, and locking element of Figs. 30A and 30B.

Fig. 36C is a top plan view of the plates in an elongated position, fasteners, and locking elements of Figs. 30C and 30D.Fig. 37A is a top perspective view of one of the plates of Figs. 30A and 30B and another preferred embodiment of instrumentation for compressing the plate and instrumentation for locking the fastener in accordance with the present invention.

Fig. 37C is a top perspective view of one of the plates of Figs. 30C and 30D and another preferred embodiment of instrumentation for compressing the plate and instrumentation for locking the fastener in accordance with the present invention.

Fig. 38A is a top plan view of one of the plates of Figs. 30A and 30B in a compressed state with the instrumentation of Fig. 37A shown in cross section engaging the ends of the plate to compress the plate in the direction of the arrows, an alternative embodiment of instrumentation for engaging an intermediary portion of the plate to compress the plate in the direction of the arrows in dotted line, and instrumentation engaging the fastener and positioned within the plate.

Fig. 38C is a top plan view of one of the plates of Figs. 30C and 30D in a compressed state with the instrumentation of Fig. 37C shown in cross section engaging the ends of the plate to compress the plate in the direction of the arrows, an alternative embodiment of instrumentation for engaging an intermediary portion of the plate to compress the plate in the direction of the arrows in dotted line, and instrumentation engaging the fastener and positioned within the plate. Fig. 39A is a side elevation view of the plate of Fig. 38A with the instrumentation shown in partial fragmentary, hidden line, and cross sectional views.

Fig. 39C is a side elevation view of the plate of Fig. 38C with the instrumentation shown in partial fragmentary, hidden line, and cross sectional views.

Fig. 40A is an exploded top perspective view of a plate, fasteners, and a locking element in accordance with another preferred embodiment of the present invention.

Fig. 40B is an exploded top perspective view of a plate, fasteners, and a locking element in accordance with another preferred embodiment of the present invention. Fig. 40C is an exploded top perspective view of a plate, fasteners, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 40D is an exploded top perspective view of a plate, fasteners, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 41 is a top plan view of a plate, fasteners, and locking elements in accordance with another preferred embodiment of the present invention.

Fig. 42 is an exploded top plan view of a plate, fasteners, and locking elements in accordance with another preferred embodiment of the present invention. Fig. 43 is an enlarged fragmentary cross sectional view of the plate, locking element, and bone screws of Fig. 42. Fig. 44 is an enlarged fragmentary cross sectional view of a plate, locking element, and bone screws in accordance with another embodiment of the present invention.

Fig. 45 is a fragmentary top plan view of another preferred embodiment of a plate and a locking element adapted to lock at least two bone screws and a fastener in accordance with the present invention.

Fig. 46 is a fragmentary top plan view of another preferred embodiment of a plate and a locking element adapted to lock at least two bone screws and a fastener in accordance with the present invention. Fig. 47a is an enlarged fragmentary cross sectional view of a locking element and bone screw in accordance with a preferred embodiment of the present invention.

Fig. 47b is an enlarged fragmentary cross sectional view of a locking element and bone screw in accordance with another preferred embodiment of the present invention.

Fig. 47c is an enlarged fragmentary cross sectional view of a locking element and bone screw in accordance with yet another embodiment of the present invention.

Fig. 47d is an enlarged fragmentary cross sectional view of the locking element and bone screw of Fig. 47c in an angled position.

Fig. 47e is an enlarged fragmentary cross sectional view of a self-locking bone screw in accordance with a further embodiment of the present invention. DETAILED DESCRIPTION OF THE DRAWINGS Reference will now be made in detail to the present preferred embodiments (exemplary embodiments) of the invention, examples of which are illustrated in the accompanying drawings. Wherever possible, the same reference numbers will be used throughout the drawings to refer to the same or like parts.

The present invention is for use in the cervical spine where dynamization is highly desired to prevent distraction pseudoarthrosis and to maintain a compressive load across the fusion interfaces. The present invention in one preferred embodiment is directed to a cervical plate generally having at least two movable segments that are attached to the vertebral bodies to be fused and connected in such a way as to permit dynamization of the vertebral bodies preferably along the longitudinal axis of the plate. The movement of the segments relative to one another may be accompanied by a reduction in the overall length of the plate. Where possible, the reference numerals in the figures are followed by a letter

"a", "b", "c", or "d" corresponding to preferred embodiments of the present invention, respectively. For example, a description of a feature identified by a reference numeral followed by the reference letter "a" and also applicable to a feature identified by a reference numeral followed by a letter "b", "c", or "d" will not be repeated for each of the corresponding reference numerals.

Figs. 1 A, 2A, 3A, 4A, 5A, 6A and7A show a preferred embodiment of a cervical plate 100a in accordance with the present invention. Plate 100a is preferably formed of a first segment 102a and a second segment 104a in moveable relationship to one another. First and second segments 102a, 104a can be of various lengths and/or configurations such that when the segments are assembled preferably overlapping at least in part, plates of various lengths and/or configurations can be formed to cover a range of sizes. First and second segments 102a, 104a can be of the same or different lengths and can be coupled to each other or to an intermediate segment as shown in Figs. 29A, 30A, 31 A, 32A, 33A, 34A, 35A, 36A, 37A, 38A, 39A, and -40A and described below in connection with other preferred embodiments of the present invention. The overall length of plate 100a and the spacing of segments 102a, 104a can be adjusted by moving segments 102a, 104a relative to one another.

In this preferred embodiment of the present invention, a detachable fastener 106a couples together first and second segments 102a, 104a. Fastener 106a is configured to be detachably attached to at least one of first and second segments 102a, 104a, to permit the assembly of two or more plate segments. Fastener 106a is detachable to permit for the assembly of the plate segments by the surgeon and allows for the complete uncoupling of first and second segments 102a, 104a from one another. As used herein, "detachable fastener" is defined as a fastener that can be assembled by the surgeon at the time of use and once attached is meant to still be removable and then reattachable by the surgeon. As shown in Fig. 7A, fastener 106a, for example, may be embodied in the form of a screw having a head 108a, a shaft 112a, and a thread 116a.

As shown in Fig. 8A, in another preferred embodiment fastener 106a' may be configured to be tightened to only one of first and second plate segments 102a, 104a so as to permit movement of first and second segments 102a, 104a relative to one another when fastener 106a' is fully tightened. For example, fastener 106a' may have a shoulder 110a adapted to bear upon second segment 104a as indicated by arrow C. Shoulder 110a is dimensioned so as to create a gap 111a between head 108a' and first segment 102a so as to still permit a specific and desired motion of first and second segments 102a, 104a relative to one another when fastener 106a' is fully tightened. The limited motion of first and second segments 102a, 104a relative to one another provides for dynamization of the spinal segment to be fused in that those vertebral bodies are allowed to move closer together to maintain contact.

As shown in Figs. 1A and 2A, first segment 102a preferably has an upper surface 118a, a lower surface 120a, a medial portion 122a, and an end 124a. First segment 102a preferably includes bone screw receiving holes 126a proximate end 124a. Bone screw receiving hole 126a is preferably configured to receive a single bone screw or the bone screw receiving holes also may be configured to receive more than one bone screw. By way of example only and not limitation, a bone screw receiving hole may be in the form of a slot sized to receive at least two bone screws.

Preferably, at least two of bone screw receiving holes 126a may be oriented in plate 100a to overlie the anterior aspect of a single cervical vertebral body adjacent a disc space to be fused, though the invention is not so limited. For example, a first pair of bone screw receiving holes 126a may be configured to overlie the anterior aspect of a first cervical vertebral body adjacent a disc space to be fused and at least a second pair of bone screw receiving holes 126a may be oriented in plate 100a to overlie the anterior aspect of a second cervical vertebral body adjacent the disc space to be fused. Bone screw receiving hole 126a may, though need not be, configured to form an interference fit with at least a portion of the trailing end of a properly dimensioned bone screw to be received therein. Bone screw receiving holes 126a may be configured, for example only, so that at least one of bone screw receiving holes 126a may hold a bone screw in a fixed relationship to the plate or may hold a bone screw in a moveable relationship, such as a variable angular relationship, described below. By way of example only and not limitation, bone screw receiving hole 126a may have a reduced dimension proximate lower surface 120a of segment 102a to form a seat 127a. Seat 127a may have a surface adapted to contact at least a portion of a bone screw inserted therein. The surface may be at least in part planar, at least in part curved, or have any other configuration suitable for contacting at least a portion of a bone screw.

End 124a of first segment 102a may also include a tool engagement area 128a adapted to cooperatively engage instrumentation for holding plate 100a and instrumentation for moving first and second segments relative to one another to induce a desired amount of compressive force across the fusion sites and to permit a desired amount of shortening of plate 100a. Medial portion 122a preferably has a fastener receiving opening 130a adapted to accommodate fastener 106a to couple first and second segments 102a, 104a to one another. Fastener receiving opening 130a is preferably configured to permit selected movement of fastener 106a therein and to permit selected motion of first and second segments 102a, 104a along the longitudinal axis of plate 100a. Fastener receiving opening 130a may include a shoulder 132a recessed from upper surface 118a of first segment 102a adapted to contact the underside of head 108a of fastener 106a in the tightened position to prevent movement of first and second segments 102a, 104a relative to one another. Alternatively, if a fastener 106a' is used, shoulder 110a contacts second segment 104a and the underside of head 108a' is positioned relative to shoulder 132a to permit movement of first and second segments 102a, 104a relative to each other along the longitudinal axis of the plate when in the tightened position providing for dynamization of the vertebral bodies to be fused to occur, if needed. Fastener 106a and fastener receiving opening 130a cooperate to prevent complete uncoupling of first and second segments 102a, 104a from one another when fastener 106a is installed. For example, fastener receiving opening 130a may be configured to prevent head 108a of fastener 106a from passing therethrough. Lower surface 120a of first segment 102a includes a tab receiving recess

134a for receiving a tab 136a described below.

Second segment 104a has an upper surface 138a, a lower surface 140a, a medial portion 142a, and an end 144a. Second segment 104a preferably has bone screw receiving holes 126a proximate end 144a. End 144a may also include a tool engagement area 146a adapted to cooperatively engage instrumentation for holding plate 100a and instrumentation for moving first and second segments 102a, 104a relative to one another to induce a desired amount of compressive force across the fusion site and to permit a desired amount of shortening of plate 100a. Medial portion 142a preferably includes a fastener receiving opening 148a for receiving a portion of fastener 106a. As first and second segments of plate 100a are modular and assembleable, fastener receiving opening 148a is configured to permit detachable attachment of fastener 106a.

Fastener receiving opening 148a preferably has a thread 150a adapted to engage with thread 116a of fastener 106a. The threaded engagement of fastener 106a to fastener receiving opening 148a permits first segment 102a and second segment 104a to be attached to each other when fastener 106a is sufficiently rotated and tightened. As fastener 106a is rotated further, first and second segments 102a, 104a are secured together and locked and do not move relative to each other. Alternatively, if fastener 106a' shown in Fig. 8A is used in the tightened position, first and second segments 102a, 104a are capable of moving relative to each other. Lower surfaces 120a, 140a of first and second segments 102a, 104a are preferably at least in part concave along at least a portion of the longitudinal axis of the plate, may be bi-concave at least in part, that is, concave along the longitudinal axis of plate 100a and concave transverse to the longitudinal axis of the plate, or may have any shape suitable for the intended purpose transverse to the longitudinal axis of the plate. A person skilled in the art will appreciate that plate 100a may be adapted for other curvatures or have no curvature without departing from the intended purpose within the broad scope of the present invention. Lower surfaces 120a, 140a are preferably adapted to contact at least a portion of the vertebral bodies to be fused and may be configured to conform to the anterior aspect of at least a portion of the vertebral bodies.

Second segment 104a preferably includes a tab 136a extending from medial portion 142a. Tab 136a is configured to cooperatively engage a tab receiving recess 134a in the lower surface 120a of first segment 102a. Tab 136a acts as a spring to maintain first and second segments 102a, 104a aligned along the longitudinal axis of plate 100a. Tab 136a also functions to limit movement of first segment 102a in a direction transverse to longitudinal axis of plate 100a to prevent end 124a from dropping down beyond a desired position. This limited movement of first segment 100a prevents medial portion 122a of first segment 102a from lifting away from medial portion 142a beyond a desired position, so that ratchetings 150a are not overly separated and rendered less effective as described in more detail below. It is appreciated that other configurations of segments 102a, 104a are possible to hold apart segments 102a, 104a and to limit movement of the segments in a direction transverse to the longitudinal axis of the plate. For example, the longitudinal curvatures of first and .second segments 102a, 104a can be slightly different to spring apart segments 102a, 104a. For example, the radius of curvature of the lower surface of segment 102a may be different than the radius of curvature of the upper surface of segment 104a.

At least a portion of lower surface 120a of first segment 102a and upper surface 138a of second segment 104a are preferably configured to interdigitate with one another to permit selected adjustment of the length of plate 100a. For example, lower surface 120a and upper surface 138a may include a surface configuration, such as ratchetings 152a, configured to cooperatively interdigitate to permit selected and sequential movement along the longitudinal axis of plate 100a. The ratchetings are preferably biased to allow movement in one preferred direction along the longitudinal axis of the plate so as to allow shortening of the plate and resist lengthening of the plate. Figs. 9A and 10A show an embodiment of ratchetings having a configuration that is useful if no movement of first and second segments 102a, 104a is desired after fastener 106a is tightened. A preferred angular relationship of the cross section of ratchetings 152aι is a 45-45-90 degree triangular relationship. As shown in Fig. 9A, in a first position, the peaks and valleys of ratchetings 152aι are cooperatively mating. Ratchetings 152a_! permit for the fixed positioning of first and second segments 102a, 104a relative to one another to create a selected length of plate 100a. As shown in Fig.10A, the peaks and valleys are separated to permit movement of the first and second segments in the directions of the arrows along the longitudinal axis of plate 100a. In order for first and second segments 102a, 104a to move relative to one another, there must be sufficient freedom of movement for the segments to move apart in order to clear the height of the peaks of ratchetings 152a-|. Accordingly, in a preferred embodiment fastener 106a is configured to have at least one position that permits movement of the first and second segments along the longitudinal axis of plate 100a as well as along an axis transverse to the longitudinal axis of plate 100a such that ratchetings 152a can move apart. Fastener 106a can be tightened to a second position to resist or prevent movement of segments 102a, 104a relative to one another. For example, movement of segments 102a, 104a can be resisted in a direction along at least a portion of the longitudinal axis of plate 100a.

Figs. 11A and 12A show another preferred embodiment of ratchetings 152a₂ having a forward-facing configuration for permitting movement in a single direction. The configuration of ratchetings 152a₂ is useful when movement of first and second segments 102a, 104a is desired to permit further shortening of the plate. A preferred angular relationship of the triangular cross section of ratchetings 152a₂ is a 30-60-90 degree triangular relationship. As shown in Fig.12A, due to the forward facing angle of ratchetings 152a₂, sliding movement of first and second segments 102a, 104a in the direction, as indicated by the arrow, along the longitudinal axis of plate 100a is facilitated by the ramped surface 154a. In contrast, sliding movement in the opposite direction is restricted by vertical wall 156a. Movement of segments 102a, 104a is limited to a single direction with ratchetings 152aι and by limiting the separation of segments 102a, 104a along an axis transverse to the longitudinal axis of plate 100a with fastener 106a or 106a'.

In a preferred embodiment, fastener 106a or 106a' is configured to have at least one position that permits movement of first and second segments 102a, 104a in both directions along the longitudinal axis of plate 100a as well as along an axis transverse to the longitudinal axis of plate 100a such that ratchetings 152a₂ can move apart. For example, in a first position fastener 106a can be less than fully tightened to plate 100a as desired by the surgeon to permit movement of first and second segments relative to each other. Fastener 106a' can further have a second position that permits movement of segments 102a, 104a relative to one another only in a single direction along the longitudinal axis of plate 100a and limits movement along an axis transverse to the longitudinal axis of plate 100a. Therefore, plate 100a can be shortened if the distance between the two adjacent vertebral bodies decreases, even after plate 100a is installed, so that the vertebral bodies are not held apart by plate 100a, to prevent the occurrence of pseudoarthrosis. One of the benefits of a forward-facing configuration of ratchetings 152a₂ is the ability to store and impart a compressive load across the fusion site. The compressive load stored may be applied by the surgeon and/or compressive loads that occur randomly with neck motion during the healing phase. First and second segments 102a, 104a may be pre-adjusted to correspond to the appropriate size and spacing of the adjacent vertebral bodies to be fused prior to placement of plate 100a against the vertebral bodies by moving first and second segments 102a, 104a relative to one another while fastener 106a is only partially tightened for the purpose of appropriately adjusting the length of the plate. Then, fastener 106a may be further tightened to secure first and second segments 102a, 104a in the desired position.

Plates 100a and 100b preferably include at least one bone screw lock adapted to lock to the plate only a single bone screw inserted into one of the bone screw receiving holes. The plates of the present invention may include more than one bone screw lock, each lock being adapted to lock to the plate only a single bone screw inserted into one of the bone screw receiving holes. Preferably, the bone screw lock physically blocks the bone screw from unwanted loosening or unwanted backing out from the plate.

Figs. 47a-47d show preferred embodiments of locking elements for locking bone screws in accordance with the present invention. For example, the bone screw locks may be in the form of a screw, a rivet, a cap, or a cover. It is appreciated that any locking element for locking a single one of the bone screws known to one of ordinary skill in the art would be within the scope of the present invention.

Fig. 47a shows an enlarged fragmentary cross sectional view of a locking element 172aι and a bone screw 174a-|. Locking element 172aι threadably engages bone screw receiving hole 126a to prevent bone screw 174aι from backing out. In this embodiment, locking element 172aι locks bone screw 174aι in a fixed relationship to plate 100a.

Fig. 47b is an enlarged fragmentary cross sectional view of a locking element 172a₂ and a bone screw 174a₂. Locking element 172a₂ threadably engages bone screw receiving hole 126a to prevent bone screw 174a₂ from backing out. In this embodiment, locking element 172a₂ is adapted to hold bone screw 174a₂ in an angular relationship to plate 100a. Examples of preferred fixed-angled single locking elements are taught by Michelson in U.S. Patent No. 6,139,550, (the '550 patent) entitled "Skeletal Plating System," the disclosure of which is hereby incorporated by reference herein. Locking element 172a₂ may also permit movement of bone screw 174a₂ relative to plate 100a.

Figs. 47c and 47d are enlarged fragmentary cross sectional views of a locking element 172a₃ and bone screw 174 a₃ in accordance with another embodiment of the present invention. Locking element 172 a₃ threadably engages bone screw receiving hole 126a to prevent bone screw 174 a₃ from backing out. In this embodiment, locking element 172 a₃ is adapted to hold bone screw 174 a₃ in an angular relationship to plate 100a. Locking element 172 a₃ may also permit movement of bone screw 174 a₃ relative to plate 100. Locking element 172 a₃ is adapted to adjustably lock bone screw 174 a₃ in a variable angle relationship relative to plate 100a. Bone screw 174 a₃ preferably has a rounded head 176 a₃ that cooperates with the bottom surface of single locking element 172 a₃, thus allowing screw 1 4 a₃ to move relative to plate 100a. Examples of preferred variable-angled single locking elements are taught by Michelson in the '550 patent the disclosure of which is hereby incorporated by reference herein.

Fig. 47e is an enlarged fragmentary cross sectional view of a self-locking bone screw 174a in accordance with another embodiment of the present invention. Bone screw 174a₄ has thread 178a adapted to threadably engage bone screw receiving hole 126a. The thread pattern of thread 178a is has a tighter pitch than the thread pattern of the bone engaging thread of bone screw 174a . The different thread pitches prevent bone screw 174a₄ from backing out after installation is completed.

It is appreciated that various types of bone screws and single lock systems may be utilized with the plates of the present invention.

With appropriate embodiments of the plates described herein, the surgeon may induce a desired amount of "preload," or compressive force across the fusion site after plate attachment by moving first and second segments 102a, 104a toward one another to shorten the length of plate 100 as desired. Inducing a preload enhances fusion by maintaining a compressive force between adjacent vertebral bodies and reducing the chance that gaps might develop as new living bone replaces the dead bone during the fusion process. Figs. 13A, 14A, and15A show a preferred embodiment of instrumentation

200a for compressing and locking plate 100a. Instrumentation 200a has a handle 202a with a pair of tongs 204a, 206a in moveable relationship to each. Tongs 204a, 206a are configured to cooperatively engage ends 124a, 144a of first and second segments, 102a, 104a, respectively. Instrumentation 200a may be used to hold and position plate 100a in a desired position at the fusion site during at least a portion of the procedure for installing plate 100a. Any instrument capable of engaging the plate so as to serve the intended purpose would be within the scope of the instrumentation and method of the present invention. As an example only, methods and instrumentation for installing plates to the cervical spine, including a pilot hole forming punch to create bone screw receiving holes in the vertebral bodies coaxially aligned with the bone screw receiving holes with the plate, are taught and described by Michelson in the '721 patent, incorporated by reference herein. After segments 102a, 104a have been attached to the adjacent vertebral bodies with an appropriate fastening element, such as bone screws, instrument 200a can be used to move segments 102a, 104a toward one another to shorten the length of plate 100a and create a compressive load across the disc space. After the desired length of plate 100a is achieved, an instrument 208a having a head 210a configured to cooperatively engage fastener 106a is used to tighten fastener 106a to secure first and second segments 102a, 104a in a desired position. When in a secured position, segments 102a, 104a may maintain a compressive load across the disc space if desired. Head 210a of instrument 208a may have a hex-shaped configuration.

Figs. 1 B, 2B, 4B, 7B, 8B, and 15B show another preferred embodiment of a cervical plate 100b in accordance with the present invention. In this preferred embodiment of the present invention, plate 100b may include at least one bone screw lock adapted to lock to the plate only a single bone screw inserted into one of bone screw receiving holes 126b such as described above in relation to plate 100a and a non-detachable fastener 106b configured to couple together first and second segments 102b, 104b. Fastener 106b is configured to be non-detachably attached to at least one of first and second segments 102b, 104b to couple together two or more plate segments. Fastener 106b is non-detachable to prevent non-destructive complete uncoupling of first and second segments 102b, 104b from one another during normal use. As used herein, "non-detachable fastener" is defined as a fastener that once attached is not meant to be removed and then reattached. As shown in Fig. 7B, fastener 106b, for example, may be embodied in the form of a rivet having a head 108b, a shaft 112b, and a base 114b. By way of example only and not limitation, base 114b may be coupled to second segment 104b so that it is permanently attached, but is still capable of an element of rotation about its longitudinal axis. Shaft 112b of fastener 106b preferably has a thread 116b.

Fastener receiving opening 148b of plate 100b is configured to permit non- detachable attachment of fastener 106b while permitting an element of rotation of fastener 106b about its longitudinal axis. For example as shown in Fig. 2B, the bottom portion of fastener receiving opening 148b proximate lower surface 140b of second segment 104b may have a smaller dimension than the maximum dimension of base 114b (e.g. flared portion of a rivet) of fastener 106b so as to prevent passage of the end portion therethrough. Moreover, the bottom portion of fastener receiving opening 148b may be beveled to accommodate base 114b (e.g. flared portion) of fastener 106b so that it is generally flush or recessed to the bottom surface and preferably does not impede close contact of lower surface 140b with the surface of the vertebral bodies. The first and second plate segments may be modular components of various configurations assembled by the manufacturer of the plate and provided to the surgeon in an assembled state. In the assembled state, the plate has a non-detachable fastener that prevents non-destructive complete uncoupling of the first and second segments during normal use.

Figs. 1C, 2C, 3C, 4C, 6C, 13C, 14C, and 15C show another preferred embodiment of a cervical plate 100c in accordance with the present invention. In this preferred embodiment of the present invention, plate 100c may include a detachable fastener configured to couple together first and second segments 102c, 104c such as described above in relation to plate 100a and a bone screw lock adapted to lock at least two bone screws inserted in bone screw receiving holes 126c. Bone screw locks 172c are coupled to plate 100c and may be removable or may be non-detachably attached to plate 100c. Bone screw locks 172c may be coupled to plate 100c prior to the insertion of the bone screws into bone screw receiving holes 126c. Alternatively, the bone screw locks may be coupled to the plate after the insertion of the bone screws into the bone screw receiving holes.

As shown in Figs. 1C, 2C, 3C,4C, 14C, and 15C, by way of example only and not limitation, bone screw lock 172c may have a tool engagement portion 174c adapted to cooperatively engage an instrument used for coupling bone screw lock 172c to plate 100c and at least one cutout 176c. Each cutout 176c is oriented so as to permit introduction of a bone screw into an adjacent bone screw receiving hole when bone screw lock 172c is coupled to plate 100c and in the appropriate orientation. It is appreciated that other configurations of the bone screw lock are possible so as to permit introduction of a bone screw into a bone screw receiving hole adjacent to the bone screw lock without interference from the bone screw lock. Plate 100c may have an opening 178c for receiving at least a portion of locking element 172c and may, but need not, include a recess 180c for receiving at least a portion of locking element 172c therein. Bone screw lock 172c may have a stem 182c configured to fit at least in part within opening 178c in plate 100c. Stem 182c and opening 178c may be threaded to threadably engage bone screw lock 172c to plate 100c. Alternatively, at least a portion of the interior perimeter of recess 180c and at least a portion of the perimeter of the bone screw lock may be threaded to threadably engage the bone screw lock to the plate.

In a preferred embodiment, bone screw locks 172c are configured to move from an initial position, that permits the insertion of bone screws into the bone screw receiving holes, to a final position that is adapted to extend over at least a portion of at least two of the bone screws to retain the bone screws to the plate. The bone screw lock may be adapted to be rotated from the initial position to the final position, and preferably, less than a full rotation of the bone screw lock rotates the bone screw lock from the initial position to the final position. In a preferred embodiment, the bone screw lock in the final position covers at least a portion of at least two of the bone screw receiving holes.

In another preferred embodiment, at least a portion of the bone screw lock slides from the initial position to the final position. The bone screw lock can slide over at least a portion of at least two of the bone screw receiving holes and/or slide over at least a portion of at least two bone screws in the bone screw receiving holes. The bone screw lock may be in the form of a screw, a rivet, a cap, a cover, or have any other configuration suitable for its intended purpose. The bone screw lock may have a head that is at least in part circular. Where it is desired to lock more than one bone screw to the plate with one bone screw lock, any lock suitable for locking a plurality of bone screws to an anterior cervical plate known to those of ordinary skill in the art may be utilized, including but not limited to, the bone screw locks taught by Michelson in U.S. Patent No. 6,193,721 (the 721 patent), incorporated by reference herein. Figs. 1 D, 2D, 4D, and 15D show another preferred embodiment of a cervical plate 100d in accordance with the present invention. In this preferred embodiment of the present invention, plate 100d may include a non-detachable fastener configured to couple together first and second segments 102d, 104d such as described above in relation to plate 100b and a bone screw lock adapted to lock at least two bone screws inserted into bone screw receiving holes 126d such as described above in relation to plate 100c.

Figs. 16A, 17A, 18A, 19A, 20A, 21 A, and 22A show another preferred embodiment of a cervical plate 300a having an internal compression mechanism in accordance with the present invention. Plate 300a is similar to plate 100a except that fastener receiving opening 330a and fastener 306a function as part of a mechanism to move first and second segments 302a, 304a relative to one another to change the length of plate 300a to generate a compressive load across the disc space between two adjacent vertebral bodies to be fused. Fastener receiving opening 330a includes instrument pin receiving recesses 362aι and 362a₂ for cooperating with the pin of an instrument 400a (described below) for moving first and second segments 302a, 304a relative to one another. In addition, instead of a tab 136a, plate 300a has pins 358a and tracks 360a to maintain first and second segments 302a, 304a aligned along the longitudinal axis of plate 300a. Bone screw lock 372a is adapted to lock to plate 300a at least two bone screws inserted in bone screw receiving holes 326a. As shown in Figs. 20A, 21 A, and 22A, first segment 302a preferably has two pins 358a depending therefrom for engagement in corresponding tracks 360a in second segment 304a. Pins 358a slideably engage tracks 360a, respectively, and travel therein when first and second segments 302a, 304a are moved relative to one another. Tracks 360a are staggered along the length of medial portion 342a and pins 358a are staggered along the length of medial portion 322a to maintain first and second segments 302a, 304a aligned along the longitudinal axis of plate 300a. It is appreciated that any plate configuration to achieve the intended purpose of maintaining first and second segments 302a, 304a aligned along the longitudinal axis of the plate would be within the scope of the present invention. Figs. 23A, 24A, 25A, and- 26A show a preferred embodiment of instrumentation 400a used for compressing and locking plate 300a. Instrumentation 400a has a working end 402a configured to cooperatively engage fastener receiving opening 330a and fastener 306a. After segments 302a, 304a have been attached to the adjacent vertebral bodies with an appropriate fastening element, such as bone screws, instrument 400a can be used to move segments 302a, 304a toward one another to shorten the length of plate 300a, create a compressive load across the disc space, and concurrently tighten fastener 306a (if desired) to secure first and second segments 302a, 304a in a preferred position. Working end 402a of instrument 400a preferably has a driver portion 404a configured to cooperatively engage driver receiving opening 364a in fastener 306a. Driver portion 404a is preferably hex-shaped. Working end 402a preferably has a pin 406a extending therefrom and displaced from driver portion 404a to engage one of pin receiving recesses 362aι and 362a₂, respectively, when driver portion 404a is engaged with driver receiving opening 364a in fastener 306a. With driver portion 404a engaging fastener 306a and pin 406a inserted in pin receiving recess 362 a₂ as shown in Fig. 25A, instrument 400a rotates fastener 306a in the direction of arrow A as shown in Fig. 26A to move first segment 302a toward second segment 304a in the direction of arrow B to reduce the length of plate 300a and can if desired concurrently tighten fastener 306a. The configuration of plate 300a provides for an internal compression mechanism that can be operated by a driver instrument eliminating the need for an externally applied compression apparatus for shortening plate 300a and creating a compressive load.

Figs. 19B, 20B, 21 B, 22B, and 24B show another preferred embodiment of a cervical plate 300b in accordance with the present invention similar to plate 300a. In this preferred embodiment of the present invention, plate 300b may include at least one bone screw lock adapted to lock to the plate only a single bone screw inserted into one of bone screw receiving holes 326b such as described above in relation to plate 100a and a non-detachable fastener 306b configured to couple together first and second segments 302b, 304b such as described above in relation to plate 100b. Figs. 16C, 17C 18C, 19C, 21 C, 22C, 23C, and 24C show another preferred embodiment of a cervical plate 300c in accordance with the present invention similar to plate 300a. In this preferred embodiment of the present invention, plate 300c may include a detachable fastener configured to couple together first and second segments 302c, 304c such as described above in relation to plate 100a and a bone screw lock adapted to lock at least two bone screws inserted in bone screw receiving holes 326c such as described above in relation to plate 100c. Figs. 19D, 21 D, 22D, and 24D show another preferred embodiment of a cervical plate 300d in accordance with the present invention similar to plate 300a. In this preferred embodiment of the present invention, plate 300d may include a non- detachable fastener configured to couple together first and second segments 302d, 304d such as described above in relation to plate 100b and a bone screw lock adapted to lock at least two bone screws inserted into bone screw receiving holes 326d such as described above in relation to plate 100c.

Figs. 27A and 28A show another preferred embodiment of a cervical plate 500a in accordance with the present invention. Plate 500a is similar to plate 100a except that first segment 502a is configured to receive at least a portion of second segment 504a therein in a tongue and groove configuration. As shown in Fig. 28A, first segment 502a preferably has a C-shaped cross section and second segment 504a preferably has a T-shaped cross section. The configurations of segments 502a, 504a in this embodiment of the present invention keep segments 502a, 504a aligned along the longitudinal axis of plate 500a and limit movement of segments 502a, 504a in a direction generally transverse to the longitudinal axis of plate 500a. A person of ordinary skill in the art would appreciate that other configurations of cooperatively engaging first and second segments 502a, 504a are possible without departing from the intended purpose within the broad scope of the present invention. Bone screw lock 572a is adapted to lock to plate 500a one bone screw inserted in one of bone screw receiving holes 526a.

Fig. 27B shows another preferred embodiment of a cervical plate 500b in accordance with the present invention similar to plate 500a. In this preferred embodiment of the present invention, plate 500b may include at least one bone screw lock adapted to lock to the plate only a single bone screw inserted into one of bone screw receiving holes 526b such as described above in relation to plate 100a and a non-detachable fastener 506b configured to couple together first and second segments 502b, 504b such as described above in relation to plate 100b.

Fig. 27C shows another preferred embodiment of a cervical plate 500c in accordance with the present invention similar to plate 500a. In this preferred embodiment of the present invention, plate 500c may include a detachable fastener configured to couple together first and second segments 502c, 504c such as described above in relation to plate 100a and a bone screw lock adapted to lock at least two bone screws inserted in bone screw receiving holes 526c such as described above in relation to plate 100c. Fig. 27D shows another preferred embodiment of a cervical plate 500d in accordance with the present invention similar to plate 500a. In this preferred embodiment of the present invention, plate 500d may include a non-detachable fastener configured to couple together first and second segments 502d, 504d such as described above in relation to plate 100b and a bone screw lock adapted to lock at least two bone screws inserted into bone screw receiving holes 526d such as described above in relation to plate 100c.

Figs. 29A, 30A, 31 A, 32A, 33A, 34A, 35A, and -36A show another preferred embodiment of a cervical plate 600a in accordance with the present invention. Plate 600a is similar to plate 100a except that it is configured for use across two levels of the cervical spine. In addition to the elements of plate 100a, plate 600a further includes an intermediate third segment 666a between first and second segments 602a, 604a. Third segment 666a has a first end 668a configured to cooperatively engage first segment 602a. Third segment 666a has a second end 670a configured to cooperatively engage second segment 604a. Third segment 666a and first and second segments 602a, 604a are articulated and can be moved to vary the spacing between the bone screw receiving holes of the plate segments as well as the overall length of the plate. Third segment 666a can be made of different lengths and/or configurations to vary the distance between first and second segments 602a, 604a to further vary the spacing between the bone screw receiving holes and further vary the overall length of the plate. In a preferred embodiment of the present invention, plate 600a could be provided to the health care facility in a set of segments. For example, a set or group of six segments could include a longer and a shorter one of first, second, and third segments 602a, 604a, 666a. These segments could be assembled to cover a range of sizes. Additional intermediate segments 666a can be used to assemble a plate that covers additional levels of the spine and preferably the spacing between plate segments would be adjustable.

First end 668a of third segment 666a has similar features to second segment 604a including a fastener receiving recess 648a, bone screw receiving holes 626a, ratchetings 652a on at least a portion of its upper surface 638a, and a tab 636a. Second end 670a of third segment 666a has similar features to first segment 602a including a ratchetings 652a on at least a portion of its lower surface 620a and a tab receiving recess 634a. A first fastener 606a couples together first segment 602a to first end 668a of third segment 666a. A second fastener couples together second segment 604a to second end 670a of third segment 666a. Additional segments 666a may be added for use across more than two levels of the spine. Segments 666a are configured to be coupled together with first end 668a of one segment 666a to second end 670a of another segment 666a. Bone screw lock 672a is adapted to lock to plate 600a at least two bone screws inserted in bone screw receiving holes 626a.

Figs. 37A, 38A, and- 39A show a preferred embodiment of instrumentation 700a for compressing and locking plate 600a. Instrumentation 700a has a handle 702a with a pair of tongs 704a, 706a in moveable relationship to each. Tongs 704a, 706a are configured to cooperatively engage ends 624a, 644a of first and second segments, 602a, 604a, respectively, to shorten the overall length of the plate and to apply a desired compressive load across multiple levels of the spine. Instrumentation 700a may be used to position plate 600a in a desired position at the fusion site during at least a portion of the procedure for installing plate 600a. An instrument may be used for holding the plate such as the instrumentation disclosed in the '721 patent incorporated by reference above. Instrument 700a can be used to move segments 602a, 604a toward one another and toward third segment 666a to shorten the length of plate 600a and create a compressive load across the respective disc spaces.

As shown in Fig. 38A, an alternative embodiment of instrument 700a' may be used to move first or second segment 602a, 604a toward third segment 666a so that a compressive load may be applied to one disc space at a time. Instrument 700a' has a tong 704a' similar to tong 704a for engaging one of ends 624a, 644a of first and second segments 602a, 604a, and forked tong 707a for engaging the third segment as shown in Fig. 38A.

After the desired length of plate 600a is achieved, an instrument 708a having a head 710a configured to cooperatively engage fastener 606a is used to tighten fastener 606a to secure first, second, and third segments 602a, 604a, 666a in a desired position.

Figs. 30B, 31 B, 33B, and 35B show another preferred embodiment of a cervical plate 600b in accordance with the present invention similar to plate 600a. In this preferred embodiment of the present invention, plate 600b may include at least one bone screw lock adapted to lock to the plate only a single bone screw inserted into one of bone screw receiving holes 626b such as described above in relation to plate 100a and a non-detachable fastener 606b configured to couple together first and second segments 602b, 604b such as described above in relation to plate 100b. Figs. 29C, 30C, 31 C, 32C, 33C, 34C, 35C, 36C, 37C, 38C, and 39C show another preferred embodiment of a cervical plate 600c in accordance with the present invention similar to plate 600a. In this preferred embodiment of the present invention, plate 600c may include a detachable fastener configured to couple together first and second segments 602c, 604c such as described above in relation to plate 100a and a bone screw lock adapted to lock at least two bone screws inserted in bone screw receiving holes 626c such as described above in relation to plate 100c.

Figs. 30D, 31 D, 33D, and 35D show another preferred embodiment of a cervical plate 600d in accordance with the present invention similar to plate 600a. In this preferred embodiment of the present invention, plate 600d may include a non- detachable fastener configured to couple together first and second segments 602d, 604d such as described above in relation to plate 100b and a bone screw lock adapted to lock at least two bone screws inserted into bone screw receiving holes 626d such as described above in relation to plate 100c.

Fig. 40A shows another preferred embodiment of a cervical plate 800a in accordance with the present invention. Plate 800a is similar to plate 600a except that first segment 802a is configured to receive at least a portion of the first end 868a of third segment 866a therein in a tongue and groove configuration and second end 870a of third segment 866a is configured to receive at least a portion of second segment 804a therein, in a tongue and groove configuration. A person of ordinary skill in the art would appreciate that other configurations of cooperatively engaging first and second segments 802a, 804a are possible without departing from the intended purpose within the broad scope of the present invention. Bone screw lock 872a is adapted to lock to plate 800a at least two bone screws inserted in bone screw receiving holes 826a. Fig. 40B shows another preferred embodiment of a cervical plate 800b in accordance with the present invention similar to plate 800a. In this preferred embodiment of the present invention, plate 800b may include at least one bone screw lock adapted to lock to the plate only a single bone screw inserted into one of bone screw receiving holes 826b such as described above in relation to plate 100a and a non-detachable fastener 806b configured to couple together first and second segments 802b, 804b such as described above in relation to plate 100b.

Fig. 40C shows another preferred embodiment of a cervical plate 800c in accordance with the present invention similar to plate 800a. In this preferred embodiment of the present invention, plate 800c may include a detachable fastener configured to couple together first and second segments 802c, 804c such as described above in relation to plate 100a and a bone screw lock adapted to lock at least two bone screws inserted in bone screw receiving holes 826c such as described above in relation to plate 100c.

Fig. 40D shows another preferred embodiment of a cervical plate 800d in accordance with the present invention similar to plate 800a. In this preferred embodiment of the present invention, plate 800d may include a non-detachable fastener configured to couple together first and second segments 802d, 804d such as described above in relation to plate 100b and a bone screw lock adapted to lock at least two bone screws inserted into bone screw receiving holes 826d such as described above in relation to plate 100c. Fig. 41 shows a cervical plate 900c with locking elements 902c in accordance with another preferred embodiment of the present invention. Locking elements 902c are adapted to lock at least two bone screws installed in each of bone screw receiving holes 916c, respectively. Locking element 902c is in moveable relationship to plate 900c so that locking element 902c can be pre-installed to plate 900c prior to the insertion of bone screws into bone screw receiving holes 916c. During installation of the bone screws, locking element 902c can be slid to one side of the plate as shown in the top portion of the plate in Fig. 41 to allow for insertion of a first bone screw into a first bone screw receiving hole 916c on the opposite side of plate 900c. Locking element 902c is then moved to the opposite side of plate 900c to permit insertion of a second bone screw into the second bone screw receiving hole 916c. Locking element 902c is then moved to cover at least a portion of both first and second bone screws and can be locked in place by a screw 917c as shown in the middle and bottom portions of plate 900c in Fig. 41.

Figs. 42 and 43 show a cervical plate 1000c with locking elements 1002c in accordance with another preferred embodiment of the present invention. Locking elements 1002c are installed to cover at least a portion of two bone screw receiving holes 1016c. In this embodiment, the bone screws are installed in bone screw receiving holes 1016c and locking element 1002c is placed over at least a portion of two bone screws to lock the bone screws. Locking element 1002c can be held in place with a screw 1017c that passes at least in part through opening 1003c in locking element 1002c and engages opening 1005c in plate 1000c to lock two bone screws 1048c to plate 1000c as shown in Fig. 43. Bone screws 1048c preferably have a leading end configured for insertion into the cervical spine and a head 1049c opposite the leading end that may be configured to contact locking element 1002c. By way of example only, bone screws 1048c may be configured to be in a fixed relationship to plate 1000c such as shown in Fig. 43. Fig. 44 is a fragmentary cross sectional view of another preferred embodiment of a locking element 1002c' and bone screws 1048c'. Locking element 1002c' has a bottom surface adapted to cooperate with a rounded portion of head 1049c' of bone screws 1048c' and is adapted to hold bone screws 1048c' in an angular relationship to plate 1000c'. Examples of preferred fixed-angled locking elements are taught by Michelson the '550 patent hereby incorporated by reference herein. Locking element 1002c' may also permit movement of bone screw 1048c' relative to plate 1000c'. Locking element 1002c' may also be adapted to adjustably lock bone screws 1048c' in a variable angle relationship relative to plate 1000c'. Examples of preferred variable-angled locking elements are taught by Michelson in the '550 patent. The rounded portion of head 1049c' permits bone screws 1048c' to be in a moveable relationship, such as for example in a variable angular relationship to plate 1000c'. Other configurations are possible for the intended purpose and are within the broad scope of the present invention. Various methods for using and installing the plates of the present invention are disclosed in the '550 and '721 patents to Michelson identified above, incorporated by reference herein.

Fig. 45 shows a plate 1100c and a locking element 1180c adapted to lock at least two bone screws and a fastener 1134c in accordance with the present invention. Preferably, locking element 1180c is configured to be preinstalled to plate 1100c prior to insertion of the bone screws in bone screw receiving holes 1116c and attachment of fastener 1134c to plate 1100c. Locking element 1180c has a first position that permits insertion of bone screws in respective bone screw receiving holes 1116c and installation and/or movement of fastener 1134c. Locking element 1180c has a second position that covers at least a portion of at least two bone screw receiving holes 1116c and fastener 1134c to lock at least two bone screws and fastener 1134c to plate 1100c. Locking element 1180c may preferably be configured to rotatably and/or slideably cover at least a portion of two bone screws in bone screw receiving holes 1116c and at least a portion of fastener 1134c. Fig. 46 shows another preferred embodiment of a plate 1200c and locking element 1280c adapted to lock at least two bone screws and a fastener 1234c in accordance with the present invention. Locking element 1280c is configured to be installed to plate 1200c after insertion of bone screws in bone screw receiving holes 1216c and attachment of fastener 1234c to plate 1200c. Locking element 1280c is configured to cover at least a portion of at least two bone screw receiving holes 1216c and fastener 1234c to lock at least two bone screws and at least a portion of fastener 1234c to plate 1200c. Locking element 1280c is preferably attached to plate 1200c by a screw 1217c or by any other means suitable for the intended purpose.

The plates of present invention may include a bone screw system that allows the vertebrae to move toward an interposed bone graft, and each other if necessary, instead of keeping the vertebrae apart during the occurrence of the resorption phase of the creeping substitution process. For example, the '550 patent discloses three types of screw-plate-lock systems, which are themselves combinable with one another, as follows: (1) Passive Dynamic; (2) Self-Compressing; and (3) Active Dynamic and are incorporated by reference herein.

It is appreciated that for any of the embodiments of the plates described herein can be made of, treated, coated, combined with, comprised of, or used with any source of osteogenesis, fusion promoting substances, bone growth promoting materials, bone, bone derived substances or products, demineralized bone matrix, mineralizing proteins, ossifying proteins, bone morphogenetic proteins, hydroxyapatite, genes coding for the production of bone, substances other than bone, and bone including, but not limited to, cortical bone. The plates, screws, fasteners, and/or screw locks may also be combined with material and/or substance for inhibiting scar formation. The plates, screws, fasteners, and/or screw locks may be combined with an antimicrobial material and/or surface treated or coated to be antibacterial and/or antimicrobial, such as for example, by a silver coating. At least a portion of the bottom surface of the plates can preferably have a porous, and/or textured and/or roughened surface and may be coated with, impregnated with, or comprise of fusion promoting substances (such as bone morphogenetic proteins) so as to encourage the growth of bone along the underside of the plate from bone portion to bone portion. The textured bottom surface also provides a medium for retaining fusion promoting substances with which the bottom surface layer can be impregnated prior to installation. The bottom surface of the plate may be given the desired porous textured form by rough blasting or any other conventional technology, such as etching, plasma spraying, sintering, and casting for example. If porous so as to promote bone ingrowth, the bottom surface is formed to have a porosity or pore size in the order of 50-500 microns, and preferably 100-300 microns. Bone growth promoting substances with which the porous, textured bottom surface can be impregnated include, but are not limited to, bone morphogenetic proteins, hydroxyapatite, or hydroxyapatite tricalcium phosphate. The plate, screws, fasteners, and/or bone screw locks may include at least in part a resorbable and/or bioresorbable material which can further be impregnated with a bone growth material so that as the resorbable and/or bioresorbable material is resorbed by the body of the patient, the bone growth material is released, thus acting as a time release mechanism. The bioresorbable material may be, for example, at least in part bone. The plate of the present invention may be used in combination with a spinal fixation implant such as any object, regardless of material, that can be inserted into any portion of the spine, such as but not limited to interbody spinal implants, interbody spinal fusion implants, structural bone grafts, mesh, cages, spacers, staples, bone screws, plates, rods, tethers of synthetic cords or wires, or other spinal fixation hardware. The interbody spinal fusion implants may be at least in part bone, for example only, an allograft interbody bone graft. Alternatively, the spinal interbody spinal fusion implant may be at least in part artificial. At least one of the plate, screws, fasteners, and/or bone screw locks may be, if so desired, electrified for purposes of stimulating bone growth and contributing to bone fusion. Other embodiments of the invention will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the invention being indicated by the following claims.

Claims (1)

1. What is claimed is:

   1. A plate adapted to be applied to the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused together, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being cone at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie c of the cervical vertebral bodies and being adapted to receive at least one bone screw fo engaging the cervical vertebral body to attach said plate to the cervical spine; said first and second plate segments being configured to couple together in cooperative relationship so as to facilitate movement of said first and second plate segments in a direction toward one another along the longitudinal axis of said plate and to resist movement of said first and said second plate segments in a direction away from one another along the longitudinal axis of said plate. A plate adapted to be applied to the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused together, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive at least one bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being detachably attached to at least one of said first and second plate segments so as to permit assembly of said first and second plate segments by the surgeon and complete uncoupling of said first and second plate segments relative to one another, said fastener having a first position adapted to facilitate movement of said first and second plate segments in a direction toward one another along the longitudinal axis of said plate and to resist movement of said first and said second plate segments in a direction away from one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate only a single bone screw inserted in one of said bone screw receiving holes. A plate adapted for use in the anterior human cervical spine for contacting the anterior aspect of at least two cervical vertebral bodies to be fused, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive a bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being non-detachably attached to at least one of said first and second plate segments so as to prevent complete uncoupling of said first and second plate segments relative to one another, said fastener having a first position adapted to permit said first and second plate segments to move in only a single direction toward one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate only a single bone screw inserted in one of said bone screw receiving holes.

   4. A plate adapted for use in the anterior human cervical spine for contacting the anterior aspect of at least two cervical vertebral bodies to be fused, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive a bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being non-detachably attached to at least one of said first and second plate segments so as to prevent complete uncoupling of said first and second plate segments from one another, said fastener having a first position adapted to permit said first and second plate segments to move relative to one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate only a single bone screw inserted in one of said bone screw receiving holes.

   5. A plate adapted to be applied to the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused together, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive at least one bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being detachably attached to at least one of said first and second plate segments so as to permit assembly of said first and second plate segments by the surgeon and complete uncoupling of said first and second plate segments relative to one another, said fastener having a first position adapted to facilitate movement of said first and second plate segments in a direction toward one another along the longitudinal axis of said plate and to resist movement of said first and said second plate segments in a direction away from one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate at least two bone screws inserted in said bone screw receiving holes, respectively. 6. A plate adapted to be applied the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused together, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive at least one bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being detachably attached to at least one of said first and second plate segments so as to permit assembly of said first and second plate segments by the surgeon and complete uncoupling of said first and second plate segments from one another, said fastener having a first position adapted to permit said first and second plate segments to move relative to one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate at least two bone screws inserted in said bone screw receiving holes, respectively. 7. A plate adapted to be applied to the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused together, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive at least one bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being non-detachably attached to at least one of said first and second plate segments so as to prevent complete uncoupling of said first and second plate segments relative to one another, said fastener having a first position adapted to facilitate movement of said first and second plate segments in a direction toward one another along the longitudinal axis of said plate and to resist movement of said first and said second plate segments in a direction away from one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate at least two bone screws inserted in said bone screw receiving holes, respectively. 8. A plate adapted to be applied the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused together, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive at least one bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being non-detachably attached to at least one of said first and second plate segments so as to prevent complete uncoupling of said first and second plate segments from one another, said fastener having a first position adapted to permit said first and second plate segments to move relative to one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate at least two bone screws inserted in said bone screw receiving holes, respectively.

   9. The plate of any one of claims 1 , 2, and 4-8, wherein said first and second plate segments are configured to move in only a single direction toward one another along the longitudinal axis of said plate.

   10. The plate of any one of claims 1-8, wherein said first and second plate segments are configured to limit movement of said first and second plate segments relative to one another along the longitudinal axis of said plate.

   11. The plate of any one of claims 1 -8, wherein said first and second plate segments are configured so as to be able to completely restrict movement of said first and second plate segments relative to one another along at least a mid-longitudinal axis of said plate.

   12. The plate of any one of claims 1-8, wherein said first and second plate segments are configured so as to limit separation of said first and second plate segments relative to one another when coupled together.

   13. The plate of any one of claims 1 -8, wherein at least one of said first and second plate segments is configured to receive at least a portion of another one of said first and second plate segments therein.

   14. The plate of claim 13, wherein at least one of said first and second plate segments has a projection and at least one of said first and second plate segments has a groove configured to receive at least a portion of said projection.

   15. The plate of any one of claims 1-8, wherein said first and second plate segments when attached to the adjacent vertebral bodies, respectively, are adapted to move toward one another in response to movement of the adjacent cervical vertebral bodies toward each other.

   16. The plate of any one of claims 1-8, wherein said first and second plate segments when attached to the adjacent vertebral bodies, respectively, are adapted to move the adjacent cervical vertebral bodies toward each other in response to movement of said first and second plate segments moving toward each other.

   17. The plate of any one of claims 1-8, wherein said first and second plate segments when attached to the adjacent vertebral bodies, respectively, are adapted to maintain a compressive load across a disc space between the adjacent cervical vertebral bodies.

   18. The plate of any one of claims 1-8, wherein at least a portion of said upper surface of said second plate segment is convex at least in part along at least a portion of the longitudinal axis of said plate

   19. The plate of claim 18, wherein said concave lower surface of said first plate segment has a radius of curvature that is different than the radius of curvature of said convex upper surface of said second plate segment.

   20. The plate of any one of claims 1-8, wherein said at least first and second plate segments are configured to cooperate so as to maintain said first and second plate segments generally aligned along the longitudinal axis of said plate.

   21. The plate of any one of claims 1-8, wherein said at least first and second plate segments are configured to cooperate so as to limit movement of said first and second plate segments in a direction generally transverse to the longitudinal axis of said plate.

   22. The plate of any one of claims 1-8, wherein at least a portion of said lower surface of said first plate segment is configured to cooperatively engage at least a portion of said upper surface of said second plate segment.

   23. The plate of any one of claims 1-8, wherein said at least a portion of said lower surface of said first plate segment is configured to interdigitate with at least a portion of said upper surface of said second plate segment.

   24. The plate of claim 23, wherein said at least a portion of said lower surface of said first plate segment and said at least a portion of said upper surface of said second plate segment include ratchetings.

   25. The plate of claim 24, wherein said ratchetings are configured to permit movement of said first and second plate segments toward one another in a first direction along a mid-longitudinal axis of said plate and to restrict movement in a direction opposite to said first direction.

   26. The plate of any one of claims 1-8, wherein at least one of said first and second plate segments is selected from a group of plate segments of various lengths.

   27. The plate of any one of claims 1-8, wherein at least one of said first and second plate segments is selected from a group of plate segments of various configurations.

   28. The plate of any one of the above claims, further comprising at least a third plate segment adapted to be connected to at least one of said first and second plate segments to form said plate.

   29. The plate of claim 28, wherein said third plate segment is an intermediate plate segment configured to be coupled between at least two plate segments.

   30. The plate of claim 28, wherein at least one of said first, second, and third plate segments is selected from a group of plate segments of various lengths.

   31. The plate of claim 28, wherein at least one of said first, second, and third plate segments is selected from a group of plate segments of various configurations.

   32. The plate of claim 31 , wherein said first, second, and third plate segments are selected from a group including end segments and intermediary segments.

   33. The plate of claim 32, wherein each of said end segments is configured to connect to one of said end segments and said intermediary segments, and each of said intermediary segments is configured to connect to at least one of said end segments and said intermediary segments.

   34. The plate of claim 1 , further comprising at least one bone screw, at least one of said first and second plate segments and said bone screw cooperate to lock to said plate said at least one bone screw inserted in said bone screw receiving holes, respectively.

   35. The plate of claim 1 , further comprising at least one bone screw lock adapted to lock to said plate at least one bone screw inserted in said bone screw receiving holes, respectively.

   36. The plate of any one of claims 2-4 and 35, wherein said at least one bone screw lock has a central longitudinal axis and is adapted to engage a respective one of said bone screw receiving holes with the central longitudinal axis of said at least one bone screw lock being substantially coaxial with the central longitudinal axis of a respective one of said bone screw receiving holes.

   37. The plate of any one of claims 2-4 and 35, wherein said at least one bone screw lock is configured to threadably engage one of said bone screw receiving holes.

   38. The plate of any one of claims 2-4 and 35, wherein said at least one bone screw lock is part of a bone screw configured to threadably engage one of said bone screw receiving holes.

   39. The plate of claim 38, wherein said at least one bone screw lock has threads with different thread pitches.

   40. The plate of any one of claims 5-8 and 35, wherein said at least one bone screw lock is coupled to said plate.

   41. The plate of claim 40, wherein said at least one bone screw lock is removably coupled to said plate.

   42. The plate of claim 40, wherein said at least one bone screw lock is adapted to be coupled to said plate prior to the insertion of at least one bone screw into at least one of said bone screw receiving holes.

   43. The plate of any one of claims 5-8 and 35, wherein said at least one bone screw lock is configured to move from an initial position that permits the insertion of at least one bone screw into at least one of said bone screw receiving holes to a final position that is adapted to extend over at least a portion of at least one of the bone screws to retain the bone screw to said plate.

   44. The plate of claim 43, wherein said at least one bone screw lock in the final position covers at least a portion of at least one of said bone screw receiving holes.

   45. The plate of claim 43, wherein said at least one bone screw lock is adapted to be rotated from the initial position to the final position.

   46. The plate of claim 45, wherein less than a full rotation of said at least one bone screw lock rotates said bone screw lock from the initial position to the final position.

   47. The plate of claim 43, wherein at least a portion of said at least one bone screw lock slides from the initial position to the final position.

   48. The plate of claim 47, wherein said at least one bone screw lock slides over at least a portion of at least one of said bone screw receiving holes.

   49. The plate of claim 48, wherein said at least one bone screw lock slides over at least a portion of at least one bone screw in at least one of said bone screw receiving holes.

   50. The plate of any one of claims 5-8 and 35, wherein said at least one bone screw lock comprises at least one of a screw, a rivet, a cap, and a cover.

   51. The plate of any one of claims 5-8 and 35, wherein said at least one bone screw lock comprises a head that is at least in part circular.

   52. The plate of claim 51 , wherein said head has at least one cutout segment.

   53. The plate of claim 35, further comprising at least one fastener adapted to couple together said first and second plate segments and wherein said at least one bone screw lock is adapted to lock to said plate said at least one fastener.

   54. The plate of any one of claims 5-8, wherein said at least one bone screw lock is adapted to lock to said plate said at least one fastener.

   55. The plate of either claim 53 or 54, wherein said at least one bone screw lock covers at least a portion of at least one of said bone screw receiving holes and at least a portion of said at least one fastener.

   56. The plate of either claim 53 or 54, wherein said at least one bone screws lock slides over at least a portion of at least one bone screw in at least one of said bone screw receiving holes and at least a portion of said at least one fastener.

   57. The plate of claim 1 , further comprising at least one fastener adapted to fasten together said first and second plate segments.

   58. The plate of claim 57, wherein said fastener is detachably attached to at least one of said first and second plate segments so as to permit assembly of said first and second plate segments by the surgeon and complete uncoupling of said first and second plate segments relative to one another.

   59. The plate of claim 57, wherein said fastener is non-detachably attached to at least one of said first and second plate segments so as to prevent complete uncoupling of said first and second plate segments relative to one another.

   60. The plate of claim 57, wherein said fastener has a first position adapted to facilitate movement of said first and second plate segments in a direction toward one another along the longitudinal axis of said plate and to resist movement of said first and said second plate segments in a direction away from one another along the longitudinal axis of said plate.

   61. The plate of any one of claims 4, 6, and 8, wherein said first position of said fastener is adapted to facilitate movement of said first and second plate segments in a direction toward one another along the longitudinal axis of said plate and to resist movement of said first and said second plate segments in a direction away from one another along the longitudinal axis of said plate.

   62. The plate of any one of claims 2, 5, 7, 60, and 61 , wherein said first and second plate segments move in only a single direction toward one another along the longitudinal axis of said plate when said fastener is in said first position.

   63. The plate of any one of claims 2, 5, 7, 60, and 61 , wherein said fastener has a second position adapted to limit movement of said first and second plate segments relative to one another along the longitudinal axis of said plate.

   64. The plate of any one of claims 4, 6, 8, and 57, wherein said fastener is configured so as to be able to completely restrict movement of said first and second plate segments relative to one another along at least a mid- longitudinal axis of said plate.

   65. The plate of any one of claims 57-64, wherein said fastener passes through at least a portion of said first and second plate segments.

   66. The plate of any one of claims 57-65, wherein said fastener is configured to limit separation of said first and second plate segments relative to one another.

   67. The plate of any one of claims 57-66, wherein said fastener is configured to be tightened to only one of said at least first and second plate segments so as to permit movement of said first and second plate segments relative to one another.

   68. The plate of any one of claims 57-67, wherein said fastener is a part of a mechanism for moving said first and second plate segments relative to one another along a mid-longitudinal axis of said plate.

   69. The plate of any one of claims 57-67, in combination with an instrument configured to cooperatively engage said fastener and at least a portion of at least one of said first and second plate segments so as upon movement of said fastener with said instrument said first and second plate segments move relative to one another along a mid-longitudinal axis of said plate.

   70. The plate of claim 69, wherein said fastener is configured to be rotated at least in part by said instrument.

   71. The plate of any one of claims 2, 5, 6, and 57, wherein said fastener is a screw.

   72. The plate of any one of claims 2, 5, 6, and 57, where said fastener is at least in part threaded.

   73. The plate of any one of claims 57-72, wherein said fastener has a head.

   74. The plate of claim 73, wherein said fastener has a shaft.

   75. The plate of any one of the above claims, wherein at least one end of said plate is configured to cooperatively engage a compression tool for movement of at least one vertebral body toward another vertebral body during installation of said plate.

   76. The plate of any one of the above claims, wherein said concave part of said lower surface of said first and second plate segment is configured to conform to the anterior aspect of at least a portion of two cervical vertebral bodies.

   77. The plate of any one of the above claims, wherein at least a portion of said lower surface of said first and second plate segment is at least in part concave transverse to the longitudinal axis of the plate.

   78. The plate of any one of the above claims, wherein at least a portion of said lower surface of said first and second plate segments is roughened to promote the growth of bone along said lower surface.

   79. The plate of any one of the above claims, wherein at least a portion of said lower surface of said first and second plate segments comprises a bone ingrowth surface.

   80. The plate of any one of the above claims, wherein at least one of said bone screw receiving holes is configured to form an interference fit with at least a portion of the trailing end of a properly dimensioned bone screw to be received therein.

   81. The plate of any one of the above claims, wherein at least one of said bone screw receiving holes is configured to hold a bone screw in fixed relationship to said plate.

   82. The plate of any one of claims 1-79, wherein at least one of said bone screw receiving holes is configured to allow a bone screw to be in a moveable relationship to said plate.

   83. The plate of any one of claims 1-79, wherein at least one of said bone screw receiving holes is configured to allow a bone screw to be in a variable angular relationship to said plate.

   84. The plate of any one of the above claims, in combination with an interbody spinal fusion implant.

   85. The plate of claim 84, wherein said implant comprises at least in part bone.

   86. The plate of claim 84, wherein said implant is an allograft interbody bone graft implant.

   87. The plate of claim 84, wherein said implant is an artificial implant.

   88. The plate of any one of the above claims, in combination with a fusion promoting substance.

   89. The plate of claim 88, wherein said fusion promoting substance is at least in part other than bone.

   90. The plate of claim 88, wherein said fusion promoting substance is at least in part bone.

   91. The plate of claim 88, wherein said fusion promoting substance is hydroxyapatite.

   92. The plate of claim 88, wherein said fusion promoting substance comprises bone morphogenetic protein.

   93. The plate of claim 88, wherein said fusion promoting substance comprises genes coding for the production of bone.

   94. The plate of any one of the above claims, further comprising bone screws for engaging said plate to the cervical spine, wherein at least a portion of one of said plate and said bone screws is a bioresorbable material.

   95. The plate of claim 94, wherein said bioresorbable material is at least in part bone.

   96. The plate of any one of the above claims, in combination with a substance for inhibiting scar formation.

   97. The plate of any one of the above claims, in combination with an antimicrobial material.

   98. The plate of any one of claims 1-96, wherein said plate is treated with an antimicrobial material.

   99. The plate of any one of claims 1-83, further in combination with at least one spinal fixation implant.

   100. The plate of any one of the above claims, wherein said plate is electrified for purposes of stimulating bone growth and contributing to bone fusion.

   101. The plate of any one of claims 35-56, wherein at least one of said plate and said bone screw lock is electrified for purposes of stimulating bone growth and contributing to bone fusion.

   102. The plate of any one of claims 57-74, wherein at least one of said plate and said fastener is electrified for purposes of stimulating bone growth and contributing to bone fusion.

   103. The plate of any one of claims 35-37 and 40-56, further comprising at least one bone screw having a leading end for insertion into the cervical spine and a head opposite said leading end, said at least one bone screw lock adapted to contact said head.

   104. The plate of claim 103, wherein said at least one bone screw is configured to be in fixed relationship to said plate.

   105. The plate of claim 103, wherein said at least one bone screw is configured to be in a moveable relationship to said plate.

   106. The plate of claim 103, wherein at least one bone screw is configured to be in a variable angular relationship to said plate.

   107. The plate of claim 103, wherein at least one of said bone screw receiving holes has a reduced dimension proximate said lower surface of said plate to form a seat, said seat having a substantially planar surface adapted to contact a lower surface of one of said bone screws.

   108. A plate system, comprising: a plate adapted to be applied to the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive a bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being detachably attached to at least one of said first and second plate segments so as to permit assembly of said first and second plate segments by the surgeon and complete uncoupling of said first and second plate segments from one another, said fastener having a first position adapted to permit said first and second plate segments to move relative to one another along the longitudinal axis of said plate; at least one bone screw lock adapted to lock to said plate only a single bone screw inserted in one of said bone screw receiving hole; and an instrument configured to cooperatively engage said fastener and at least a portion of at least one of said first and second plate segments so as upon movement of said fastener with said instrument said first and second plate segments move relative to one another along the longitudinal axis of said plate. A plate system, comprising: a plate adapted for use in the anterior human cervical spine for contacting the anterior aspect of at least two cervical vertebral bodies, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive a bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being non-detachably attached to at least one of said first and second plate segments so as to prevent complete uncoupling of the first and second plate segments from one another, said fastener having a first position adapted to permit said first and second plate segments to move relative to one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate only a single bone screw inserted in one of said bone screw receiving holes; and an instrument configured to cooperatively engage said fastener and at least a portion of at least one of said first and second plate segments so as upon movement of said fastener with said instrument said first and second plate segments move relative to one another along the longitudinal axis of said plate. A plate system, comprising: a plate adapted to be applied to the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive at least one bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being detachably attached to at least one of said first and second plate segments so as to permit assembly of said first and second plate segments by the surgeon and complete uncoupling of said first and second plate segments from one another, said fastener having a first position adapted to permit said first and second plate segments to move relative to one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate at least two bone screws inserted in said bone screw receiving holes, respectively; and an instrument configured to cooperatively engage said fastener and at least a portion of at least one of said first and second plate segments so as upon movement of said fastener with said instrument said first and second plate segments move relative to one another along the longitudinal axis of said plate. A plate system, comprising: a plate adapted to be applied to the anterior human cervical spine for contacting the anterior aspects of at least two cervical vertebral bodies to be fused, said plate comprising: at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and at least a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, said at least first and second plate segments adapted to be connected to one another and at least in part overlapped to form said plate, said at least first and second plate segments being in a moveable relationship to one another along a longitudinal axis of said plate, each of said at least first and second plate segments including: a lower surface adapted to contact at least one of the cervical vertebral bodies and an upper surface opposite said lower surface, said lower surface being concave at least in part along at least a portion of the longitudinal axis of said plate; at least one bone screw receiving hole extending from said upper surface through said lower surface, each of said bone screw receiving holes adapted to overlie one of the cervical vertebral bodies and being adapted to receive at least one bone screw for engaging the cervical vertebral body to attach said plate to the cervical spine; at least one fastener adapted to couple together said first and second plate segments, said fastener being non-detachably attached to at least one of said first and second plate segments so as to prevent complete uncoupling of said first and second plate segments from one another, said fastener having a first position adapted to permit said first and second plate segments to move relative to one another along the longitudinal axis of said plate; and at least one bone screw lock adapted to lock to said plate at least two bone screws inserted in said bone screw receiving holes, respectively; and an instrument configured to cooperatively engage said fastener and at least a portion of at least one of said first and second plate segments so as upon movement of said fastener with said instrument said first and second plate segments move relative to one another along the longitudinal axis of said plate.

   112. The system of any one of claims 108-111 , wherein said first and second plate segments are configured to move in only a single direction toward one another along the longitudinal axis of said plate.

   113. The system of any one of claims 108-111 , wherein said first and second plate segments are configured to limit movement of said first and second plate segments relative to one another along the longitudinal axis of said plate.

   114. The system of any one of claims 108-111 , wherein said first and second plate segments are configured so as to be able to completely restrict movement of said first and second plate segments relative to one another along at least a mid-longitudinal axis of said plate.

   115. The system of any one of claims 108-111 , wherein said first and second plate segments are configured so as to limit separation of said first and second plate segments relative to one another when coupled together.

   116. The system of any one of claims 108-111 , wherein at least one of said first and second plate segments is configured to receive at least a portion of another one of said first and second plate segments therein.

   117. The system of claim 116, wherein at least one of said first and second plate segments has a projection and at least one of said first and second plate segments has a groove configured to receive at least a portion of said projection.

   118. The system of any one of claims 108-111 , wherein said first and second plate segments when attached to the adjacent vertebral bodies, respectively, are adapted to move toward one another in response to movement of the adjacent cervical vertebral bodies toward each other.

   119. The system of any one of claims 108-111 , wherein said first and second plate segments when attached to the adjacent vertebral bodies, respectively, are adapted to move the adjacent cervical vertebral bodies toward each other in response to movement of said first and second plate segments moving toward each other.

   120. The system of any one of claims 108-111 , wherein said first and second plate segments when attached to the adjacent vertebral bodies, respectively, are adapted to maintain a compressive load across a disc space between the adjacent cervical vertebral bodies.

   121. The system of any one of claims 108-111 , wherein at least a portion of said upper surface of said second plate segment is convex at least in part along at least a portion of the longitudinal axis of said plate

   122. The system of claim 121 , wherein said concave lower surface of said first plate segment has a radius of curvature that is different than the radius of curvature of said convex upper surface of said second plate segment.

   123. The system of any one of claims 108-111 , wherein said at least first and second plate segments are configured to cooperate so as to maintain said first and second plate segments generally aligned along the longitudinal axis of said plate.

   124. The system of any one of claims 108-111 , wherein said at least first and second plate segments are configured to cooperate so as to limit movement of said first and second plate segments in a direction generally transverse to the longitudinal axis of said plate.

   125. The system of any one of claims 108-111 , wherein at least a portion of said lower surface of said first plate segment is configured to cooperatively engage at least a portion of said upper surface of said second plate segment.

   126. The system of any one of claims 108-111 , wherein said at least a portion of said lower surface of said first plate segment is configured to interdigitate with at least a portion of said upper surface of said second plate segment.

   127. The system of claim 126, wherein said at least a portion of said lower surface of said first plate segment and said at least a portion of said upper surface of said second plate segment include ratchetings.

   128. The system of claim 127, wherein said ratchetings are configured to permit movement of said first and second plate segments toward one another in a first direction along a mid-longitudinal axis of said plate and to restrict movement in a direction opposite to said first direction.

   129. The system of any one of claims 108-111 , wherein at least one of said first and second plate segments is selected from a group of plate segments of various lengths.

   130. The system of any one of claims 108-111 , wherein at least one of said first and second plate segments is selected from a group of plate segments of various configurations.

   131. . The system of any one of claims 108-130, further comprising at least a third plate segment adapted to be connected to at least one of said first and second plate segments to form said plate.

   132. The system of claim 131 , wherein said third plate segment is an intermediate plate segment configured to be coupled between at least two plate segments.

   133. The system of claim 131 , wherein at least one of said first, second, and third plate segments is selected from a group of plate segments of various lengths.

   134. The system of claim 131 , wherein at least one of said first, second, and third plate segments is selected from a group of plate segments of various configurations.

   135. The system of claim 134, wherein said first, second, and third plate segments are selected from a group including end segments and intermediary segments.

   136. The system of claim 135, wherein each of said end segments is configured to connect to one of said end segments and said intermediary segments, and each of said intermediary segments is configured to connect to at least one of said end segments and said intermediary segments.

   137. The system of either claim 108 or 109, wherein said at least one bone screw lock has a central longitudinal axis and is adapted to engage a respective one of said bone screw receiving holes with the central longitudinal axis of said at least one bone screw lock being substantially coaxial with the central longitudinal axis of a respective one of said bone screw receiving holes.

   138. The system of either of claim 108 or 109, wherein said at least one bone screw lock is configured to threadably engage one of said bone screw receiving holes.

   139. The system of either claim 108 or 109, wherein said at least one bone screw lock is part of a bone screw configured to threadably engage one of said bone screw receiving holes.

   140. The system of claim 139, wherein said at least one bone screw lock has threads with different thread pitches.

   141. The system of either claim 110 or 111 , wherein said at least one bone screw lock is coupled to said plate.

   142. The system of claim 141 , wherein said at least one bone screw lock is removably coupled to said plate.

   143. The system of claim 141 , wherein said at least one bone screw lock is adapted to be coupled to said plate prior to the insertion of at least one bone screw into at least one of said bone screw receiving holes.

   144. The system of either claim 110 or 111 , wherein said at least one bone screw lock is configured to move from an initial position that permits the insertion of at least one bone screw into at least one of said bone screw receiving holes to a final position that is adapted to extend over at least a portion of at least one of the bone screws to retain the bone screw to said plate.

   145. The system of claim 144, wherein said at least one bone screw lock in the final position covers at least a portion of at least one of said bone screw receiving holes.

   146. The system of claim 144, wherein said at least one bone screw lock is adapted to be rotated from the initial position to the final position.

   147. The system of claim 146, wherein less than a full rotation of said at least one bone screw lock rotates said bone screw lock from the initial position to the final position.

   148. The system of claim 144, wherein at least a portion of said at least one bone screw lock slides from the initial position to the final position.

   149. The system of claim 148, wherein said at least one bone screw lock slides over at least a portion of at least one of said bone screw receiving holes.

   150. The system of claim 149, wherein said at least one bone screw lock slides over at least a portion of at least one bone screw in at least one of said bone screw receiving holes.

   151. The system of either claim 110 or 111 , wherein said at least one bone screw lock comprises at least one of a screw, a rivet, a cap, and a cover.

   152. The system of either claim 110 or 111 , wherein said at least one bone screw lock comprises a head that is at least in part circular.

   153. The system of claim 152, wherein said head has at least one cutout segment.

   154. The system of either claim 110 or 111 , wherein said at least one bone screw lock is adapted to lock to said plate said at least one fastener.

   155. The system of claim 154, wherein said at least one bone screw lock covers at least a portion of at least one of said bone screw receiving holes and at least a portion of said at least one fastener.

   156. The system of claim 154, wherein said at least one bone screws lock slides over at least a portion of at least one bone screw in at least one of said bone screw receiving holes and at least a portion of said at least one fastener.

   157. The system of any one of claims 108-156, wherein said first position of said fastener is adapted to facilitate movement of said first and second plate segments in a direction toward one another along the longitudinal axis of said plate and to resist movement of said first and said second plate segments in a direction away from one another along the longitudinal axis of said plate.

   158. The system of any one of claims 108-157, wherein said first and second plate segments move in only a single direction toward one another along the longitudinal axis of said plate when said fastener is in said first position.

   159. The system of any one of claims 108-157, wherein said fastener has a second position adapted to limit movement of said first and second plate segments relative to one another along the longitudinal axis of said plate.

   160. The system of any one of claims 108-156, wherein said fastener is configured so as to be able to completely restrict movement of said first and second plate segments relative to one another along at least a mid-longitudinal axis of said plate.

   161. The system of any one of claims 108-160, wherein said fastener passes through at least a portion of said first and second plate segments.

   162. The system of any one of claims 108-161 , wherein said fastener is configured to limit separation of said first and second plate segments relative to one another.

   163. The system of any one of claims 108-162, wherein said fastener is configured to be tightened to only one of said at least first and second plate segments so as to permit movement of said first and second plate segments relative to one another.

   164. The system of any one of claims 108-163, wherein said fastener is a part of a mechanism for moving said first and second plate segments relative to one another along a mid-longitudinal axis of said plate.

   165. The system of any one of claims 108-111 , wherein said fastener is configured to be rotated at least in part by said instrument.

   166. The system of either claim 108 or 110, wherein said fastener is a screw.

   167. The system of either claim 108 or 110, where said fastener is at least in part threaded.

   168. The system of any one of claims 108-167, wherein said fastener has a head.

   169. The system of claim 168, wherein said fastener has a shaft.

   170. The system of any one of claims 108-169, wherein at least one end of said plate is configured to cooperatively engage a compression tool for movement of at least one vertebral body toward another vertebral body during installation of said plate.

   171. The system of any one of claims 108-170, wherein said concave part of said lower surface of said first and second plate segment is configured to conform to the anterior aspect of at least a portion of two cervical vertebral bodies.

   172. The system of any one of claims 108-171 , wherein at least a portion of said lower surface of said first and second plate segment is at least in part concave transverse to the longitudinal axis of the plate.

   173. The system of any one of claims 108-172, wherein at least a portion of said lower surface of said first and second plate segments is roughened to promote the growth of bone along said lower surface.

   174. The system of any one of claims 108-173, wherein at least a portion of said lower surface of said first and second plate segments comprises a bone ingrowth surface.

   175. The system of any one of claims 108-174, wherein at least one of said bone screw receiving holes is configured to form an interference fit with at least a portion of the trailing end of a properly dimensioned bone screw to be received therein.

   176. The system of any one of claims 108-175, wherein at least one of said bone screw receiving holes is configured to hold a bone screw in fixed relationship to said plate.

   177. The system of any one of claims 108-174, wherein at least one of said bone screw receiving holes is configured to allow a bone screw to be in a moveable relationship to said plate.

   178. The system of any one of claims 108-174, wherein at least one of said bone screw receiving holes is configured to allow a bone screw to be in a variable angular relationship to said plate.

   179. The system of any one of claims 108-178, in combination with an interbody spinal fusion implant.

   180. The system of claim 179, wherein said implant comprises at least in part bone.

   181. The system of claim 179, wherein said implant is an allograft interbody bone graft implant.

   182. The system of claim 179, wherein said implant is an artificial implant.

   183. The system of any one of claims 108-182, in combination with a fusion promoting substance.

   184. The system of claim 183, wherein said fusion promoting substance is at least in part other than bone.

   185. The system of claim 183, wherein said fusion promoting substance is at least in part bone.

   186. The system of claim 183, wherein said fusion promoting substance is hydroxyapatite.

   187. The system of claim 183, wherein said fusion promoting substance comprises bone morphogenetic protein.

   188. The system of claim 183, wherein said fusion promoting substance comprises genes coding for the production of bone.

   189. The system of any one of claims 108-188, further comprising bone screws for engaging said plate to the cervical spine, wherein at least a portion of one of said plate and said bone screws is a bioresorbable material.

   190. The system of claim 189, wherein said bioresorbable material is at least in part bone.

   191. The system of any one of claims 108-190, in combination with a substance for inhibiting scar formation.

   192. The system of any one of claims 108-191 , in combination with an antimicrobial material.

   193. The system of any one of claims 108-191 , wherein said plate is treated with an antimicrobial material.

   194. The system of any one of claims 108-178, further in combination with at least one spinal fixation implant.

   195. The system of any one of claims 108-194, wherein at least one of said plate and said bone screw lock is electrified for purposes of stimulating bone growth and contributing to bone fusion.

   196. The system of any one of claims 108-138 and 140-156, further comprising at least one bone screw having a leading end for insertion into the cervical spine and a head opposite said leading end, said at least one bone screw lock adapted to contact said head.

   197. The system of claim 196, wherein said at least one bone screw is configured to be in fixed relationship to said plate.

   198. The system of claim 196, wherein said at least one bone screw is configured to be in a moveable relationship to said plate.

   199. The system of claim 196, wherein at least one bone screw is configured to be in a variable angular relationship to said plate.

   200: The system of claim 196, wherein at least one of said bone screw receiving holes has a reduced dimension proximate said lower surface of said plate to form a seat, said seat having a substantially planar surface adapted to contact a lower surface of one of said bone screws.

   201. A method for stabilizing at least two adjacent vertebral bodies in the cervical human spine, comprising the steps of: providing a plate of appropriate length adapted to overlap at least a portion of two adjacent cervical vertebral bodies anteriorly, said plate having at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, the first and second plate segments being in moveable relationship to one another along a longitudinal axis of the plate, the first and second plate segments being configured to couple together in cooperative relationship; inserting at least two bone screws through the first plate segment of the plate and into one of the vertebral bodies adjacent the disc space to be fused; inserting at least two bone screws through the second plate segment and into the other of the vertebral bodies adjacent the disc space to be fused; and permitting movement of the first and second plate segments attached to the adjacent vertebral bodies relative to one another in a direction toward one another along the longitudinal axis of the plate and resisting movement of the first and second plate segments in a direction away from one another along the longitudinal axis of the plate. A method for stabilizing at least two adjacent vertebral bodies in the cervical human spine, comprising the steps of: providing a plate of appropriate length adapted to overlap at least a portion of two adjacent cervical vertebral bodies anteriorly, said plate having at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, the first and second plate segments being in moveable relationship to one another along a longitudinal axis of the plate, the first and second plate segments fastened together by a fastener being detachably attached to at least one of the first and second plate segments so as to permit assembly of the plate segments by the surgeon and complete uncoupling of the first and second plate segments from one another; inserting at least a first bone screw through the first plate segment of the plate and into one of the vertebral bodies adjacent the disc space to be fused; inserting at least a second bone screw through the second plate segment and into the other of the vertebral bodies adjacent the disc space to be fused; locking at least one of the bone screws with at least one bone screw lock adapted to lock to the plate only a single bone screw; and permitting movement of the first and second plate segments attached to the adjacent vertebral bodies relative to one another. A method for stabilizing at least two adjacent vertebral bodies in the cervical human spine, comprising the steps of: providing a plate of appropriate length adapted to overlap at least a portion of two adjacent cervical vertebral bodies anteriorly, said plate having at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, the first and second plate segments being in moveable relationship to one another along a longitudinal axis of the plate, the first and second plate segments fastened together by a fastener being non-detachably attached to at least one of the first and second plate segments so as to prevent complete uncoupling of the first and second plate segments from one another; inserting at least a first bone screw through the first plate segment of the plate and into one of the vertebral bodies adjacent the disc space to be fused; inserting at least a second bone screw through the second plate segment and into the other of the vertebral bodies adjacent the disc space to be fused; locking at least one of the bone screws with at least one bone screw lock adapted to lock to the plate only a single bone screw; and permitting movement of the first and second plate segments attached to the adjacent vertebral bodies relative to one another.

   204. A method for stabilizing at least two adjacent vertebral bodies in the cervical human spine, comprising the steps of: providing a plate of appropriate length adapted to overlap at least a portion of two adjacent cervical vertebral bodies anteriorly, said plate having at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, the first and second plate segments being in moveable relationship to one another along a longitudinal axis of the plate, the first and second plate segments fastened together by a fastener being detachably attached to at least one of the first and second plate segments so as to permit assembly of the plate segments by the surgeon and complete uncoupling of the first and second plate segments from one another; inserting at least two bone screws through the first plate segment of the plate and into one of the vertebral bodies adjacent the disc space to be fused; inserting at least two bone screws through the second plate segment and into the other of the vertebral bodies adjacent the disc space to be fused; locking at least two of the bone screws with at least one bone screw lock adapted to lock to the plate at least two bone screws; and permitting movement of the first and second plate segments attached to the adjacent vertebral bodies relative to one another.

   205. A method for stabilizing at least two adjacent vertebral bodies in the cervical human spine, comprising the steps of: providing a plate of appropriate length adapted to overlap at least a portion of two adjacent cervical vertebral bodies anteriorly, said plate having at least a first plate segment adapted to be attached to one of the adjacent vertebral bodies to be fused and a second plate segment adapted to be attached to another one of the adjacent vertebral bodies to be fused, the first and second plate segments being in moveable relationship to one another along a longitudinal axis of the plate, the first and second plate segments fastened together by a fastener being non-detachably attached to at least one of the first and second plate segments so as to prevent complete uncoupling of the first and second plate segments from one another; inserting at least two bone screws through the first plate segment of the plate and into one of the vertebral bodies adjacent the disc space to be fused; inserting at least two bone screws through the second plate segment and into the other of the vertebral bodies adjacent the disc space to be fused; locking at least two of the bone screws with at least one bone screw lock adapted to lock to the plate at least two bone screws; and permitting movement of the first and second plate segments attached to the adjacent vertebral bodies relative to one another.

   206. The method of any one of claims 201-205, wherein the permitting step includes the step of permitting movement of the first and second plate segments in only a single direction toward one another.

   207. The method of any one of claims 201-205, wherein the permitting step includes the step of allowing but not causing the movement of the adjacent vertebral bodies by movement of the first and second plate segments of the plate.

   208. The method of claim 207, wherein the permitting step includes the first and second plate segments being free to move toward one another.

   209. The method of any one of claims 201-205, wherein the permitting step includes the step of allowing movement of the first and second plate segments of the plate in response to movement of the adjacent vertebral bodies.

   210. The method of any one of claims 201-205, wherein the permitting step includes the sub-step of limiting the movement of the first and second plate segments relative to one another to sequential increments along the longitudinal axis of the plate.

   211. The method of any one of claims 201-205, wherein the permitting step includes the step of causing movement of the adjacent vertebral bodies by moving the first and second plate segments relative to one another.

   212. The method of claim 211 , wherein the step of causing movement of the adjacent vertebral bodies includes the step of generating a compressive load across the disc space between the adjacent vertebral bodies.

   213. The method of claim 212, wherein the permitting step includes the first and second plate segments being free to move toward one another.

   214. The method of claim 211 , wherein the step of causing movement of the adjacent vertebral bodies includes the step of storing a compressive load across the disc space between the adjacent vertebral bodies.

   215. The method of claim 214, wherein the permitting step includes the first and second plate segments being in fixed relationship to one another.

   216. The method of claim 201 , further comprising the step of providing a fastener to fasten together the first and second plate segments.

   217. The method of any one of claims 202-205 and 216, further comprising the steps of providing an instrument configured to cooperatively engage the fastener and at least a portion of at least one of the first and second plate segments, and utilizing the instrument to move the fastener and the first and second plate segments relative to one another along a mid-longitudinal axis of the plate.

   218. The method of claim 217, wherein the utilizing step includes the sub-step of rotating the fastener at least in part with the instrument.

   219. The method of claims 202-205 and 216, further comprising the step of tightening the fastener from a first position to a second position to resist movement of the first and second plate segments relative to each other in at least one direction.

   220. The method of claim 219, wherein the tightening step includes resisting movement of the first and second plate segments relative to one another when the fastener is in the second position.

   221. The method of claim 219, wherein the tightening step includes permitting movement of the first and second plate segments relative to one another when the fastener is in the second position.

   222. The method of claim 221 , wherein the wherein the tightening step includes limiting the movement of the first and second plate segments relative to one another to one direction along the longitudinal axis of the plate.

   223. The method of claim 221 , wherein the tightening step includes limiting the movement of the first and second plate segments relative to one another to sequential increments along the longitudinal axis of the plate.

   224. The method of claim 219, wherein the tightening step includes tightening the fastener to cause the fastener to tighten to the first plate segment while permitting movement of the first and second plate segments relative to one another.

   225. The method of any one of claims 201 -205, further comprising the step of adjusting the overall length of the plate by moving the first and second plate segments relative to each other.

   226. The method of any one of claims 201 -225, wherein the providing step includes selecting at least one of the first and second plate segments from a group of plate segments of various lengths.

   227. The method of any one of claims 201-225, wherein the providing step includes selecting at least one of the first and second plate segments from a group of plate segments of various configurations.

   228. The method of any one of claims 201-227, wherein the providing step includes providing a plate having at least a third plate segment.

   229. The method of claim 228, wherein the providing step includes selecting at least one of the first, second, and third plate segments from a group of plate segments of various lengths.

   230. The method of claim 228, wherein the providing step includes selecting at least one of the first, second, and third plate segments from a plurality of plate segments of various configurations.

   231. The method of claim 201 , further comprising the step of locking at least one of the bone screws to the plate with a bone screw lock.

   232. The method of any one of claims 202-205 and 231 , wherein the permitting step occurs prior to the locking step.

   233. The method of any one of claims 201 -205, wherein the permitting step includes the sub-step of moving the first and second plate segments relative to one another after the step of inserting the bone screws.

   234. The method of any one of claims 201-205, wherein the permitting step includes the sub-step of moving the first and second plate segments relative to one another before the step of inserting the bone screws.

   235. The method of any one of claims 201-205, wherein the permitting step includes the sub-step of applying a compressive load to the adjacent vertebral bodies.

   236. The method of any one of claims 201 -205, wherein the permitting step includes moving the first and second plate segments from a first position to a second position.

   237. The method of any one of claims 201-236, further comprising the step of combining the plate with an interbody spinal fusion implant.

   238. The method of claim 237, wherein the implant comprises at least in part bone.

   239. The method of claim 237, wherein the implant is an allograft interbody bone graft implant.

   240. The method of claim 237, wherein the implant is an artificial implant.

   241. The method of any one of claims 201-240, further comprising the step of combining the plate with a fusion promoting substance.

   242. The method of claim 241 , wherein the fusion promoting substance is at least in part other than bone.

   243. The method of claim 241 , wherein the fusion promoting substance is at least in part bone.

   244. The method of claim 241 , wherein the fusion promoting substance is hydroxyapatite.

   245. The method of claim 241 , wherein the fusion promoting substance comprises bone morphogenetic protein.

   246. The method of claim 241 , wherein the fusion promoting substance comprises genes coding for the production of bone.

   247. The method of any one of claims 201-246, wherein the providing step further comprises the step of providing bone screws for engaging the plate to the cervical spine, wherein at least a portion of one of the plate and the bone screws is a bioresorbable material.

   248. The method of claim 247, wherein the bioresorbable material is at least in part bone.

   249. The method of any one of claims 201-248, further comprising the step of combining the plate with a substance for inhibiting scar formation.

   250. The method of any one of claims 201-249, further comprising the step of combining the plate with an antimicrobial material.

   251. The method of any one of claims 201-249, further comprising the step of treating the plate with an antimicrobial material.

   252. The method of any one of claims 201-251 , further comprising the step of electrifying at least one of the plate and the bone screws for purposes of stimulating bone growth and contributing to bone fusion.

   253. The method of any one of claims 202-205 and 216-251 , further comprising the step of electrifying at least one of the plate, the fastener, and the bone screws for purposes of stimulating bone growth and contributing to bone fusion.

   254. The method of any one of claims 202-205 and 231 -251 , further comprising the step of electrifying at least one of the plate, the bone screws, and the bone screw lock for purposes of stimulating bone growth and contributing to bone fusion.