AU2002317402B2 - Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety - Google Patents
Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety Download PDFInfo
- Publication number
- AU2002317402B2 AU2002317402B2 AU2002317402A AU2002317402A AU2002317402B2 AU 2002317402 B2 AU2002317402 B2 AU 2002317402B2 AU 2002317402 A AU2002317402 A AU 2002317402A AU 2002317402 A AU2002317402 A AU 2002317402A AU 2002317402 B2 AU2002317402 B2 AU 2002317402B2
- Authority
- AU
- Australia
- Prior art keywords
- group
- yne
- polar
- compound
- hydrocarbyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
-
- A—HUMAN NECESSITIES
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-
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Oncology (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0118517.2 | 2001-07-30 | ||
| GBGB0118517.2A GB0118517D0 (en) | 2001-07-30 | 2001-07-30 | Compound |
| PCT/GB2002/003488 WO2003011252A1 (en) | 2001-07-30 | 2002-07-29 | Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002317402A1 AU2002317402A1 (en) | 2003-05-29 |
| AU2002317402B2 true AU2002317402B2 (en) | 2008-08-28 |
Family
ID=9919439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002317402A Ceased AU2002317402B2 (en) | 2001-07-30 | 2002-07-29 | Pharmaceutical composition comprising lipids comprising a polar and a nonpolar moiety |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20040219202A1 (https=) |
| EP (1) | EP1411898A1 (https=) |
| JP (1) | JP2005505521A (https=) |
| CN (1) | CN100457088C (https=) |
| AU (1) | AU2002317402B2 (https=) |
| CA (1) | CA2451868A1 (https=) |
| GB (1) | GB0118517D0 (https=) |
| RU (1) | RU2294738C2 (https=) |
| WO (1) | WO2003011252A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO328803B1 (no) * | 2000-03-03 | 2010-05-18 | Thia Medica | Nye fettsyreanaloger |
| WO2004000854A1 (en) * | 2002-06-20 | 2003-12-31 | Ic Vec Limited | Sulfur-containing phospholipid derivatives |
| DE10236146A1 (de) * | 2002-07-31 | 2004-02-19 | Basf Coatings Ag | Beschichtungsstoff, Verfahren zu seiner Herstellung und seine Verwendung |
| ES2462541T3 (es) * | 2005-06-09 | 2014-05-23 | Meda Ab | Método y composición para el tratamiento de trastornos inflamatorios |
| EP3192788A1 (en) * | 2006-10-03 | 2017-07-19 | Arbutus Biopharma Corporation | Lipid containing formulations |
| WO2008052766A2 (en) * | 2006-11-03 | 2008-05-08 | Medigene Ag | Cationic colloidal carriers for delivery of active agents to the blood-brain barrier in the course of neuroinflammatory diseases |
| US8877206B2 (en) | 2007-03-22 | 2014-11-04 | Pds Biotechnology Corporation | Stimulation of an immune response by cationic lipids |
| EP2105145A1 (en) | 2008-03-27 | 2009-09-30 | ETH Zürich | Method for muscle-specific delivery lipid-conjugated oligonucleotides |
| CA2721366C (en) | 2008-04-17 | 2017-06-06 | Elizabeth Ann Vasievich | Stimulation of an immune response by enantiomers of cationic lipids |
| HUE037082T2 (hu) | 2008-11-10 | 2018-08-28 | Arbutus Biopharma Corp | Új lipidek és készítmények terápiás hatóanyagok szállítására |
| RU2394834C1 (ru) * | 2009-06-29 | 2010-07-20 | Учреждение Российской академии наук Институт химической биологии и фундаментальной медицины Сибирского отделения РАН (ИХБФМ СО РАН) | Углеводсодержащие катионные амфифилы, обладающие способностью доставлять нуклеиновые кислоты в клетки млекопитающих |
| SG11201405157PA (en) * | 2012-02-24 | 2014-10-30 | Protiva Biotherapeutics Inc | Trialkyl cationic lipids and methods of use thereof |
| CN105163753B (zh) | 2012-06-15 | 2018-12-21 | Pds生物科技公司 | 阳离子脂质疫苗组合物和使用方法 |
| RU2677658C2 (ru) | 2012-07-05 | 2019-01-18 | Тайвэн Липосом Ко, Лтд. | Способы лечения артрита |
| CN105101991A (zh) | 2012-09-21 | 2015-11-25 | Pds生物科技公司 | 改进的疫苗组合物和使用方法 |
| DK3038596T3 (da) | 2013-08-30 | 2020-04-06 | Univ Dalhousie | Sammensætninger og fremgangsmåder til fjernelse af tatoveringer |
| WO2017083820A1 (en) | 2015-11-13 | 2017-05-18 | Pds Biotechnology Corporation | Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy |
| WO2017087685A1 (en) * | 2015-11-20 | 2017-05-26 | The Regents Of The University Of California | Deformable nano-scale vehicles (dnvs) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery |
| WO2018187240A1 (en) | 2017-04-03 | 2018-10-11 | The Regents Of The University Of California | Deformable nano-scale vehicles (dnvs) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery |
| CA3084957A1 (en) | 2017-12-05 | 2019-06-13 | Pds Biotechnology Corporation | Methods and compositions comprising cationic lipids for stimulating type 1 interferon genes |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3070993D1 (en) * | 1979-12-20 | 1985-09-19 | Dennis Chapman | Polymerisable phospholipids and polymers thereof, methods for their preparation, methods for their use in coating substrates and forming liposomes and the resulting coated substrates and liposome compositions |
| IE912535A1 (en) * | 1990-07-27 | 1992-01-29 | Res Dev Foundation | Liposomes that Provide Thymic Dependent Help to Weak Vaccine¹Antigens |
| WO1995009611A2 (en) * | 1993-10-06 | 1995-04-13 | Amgen Inc. | Stable protein: phospholipid compositions and methods |
| US6187335B1 (en) * | 1997-12-31 | 2001-02-13 | Orasomal Technologies, Inc. | Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom |
| ES2244169T3 (es) * | 1998-02-09 | 2005-12-01 | Bracco International B.V. | Suministro direccionado de medios biologicamente activos. |
| GB9930533D0 (en) * | 1999-12-23 | 2000-02-16 | Mitsubishi Tokyo Pharm Inc | Nucleic acid delivery |
-
2001
- 2001-07-30 GB GBGB0118517.2A patent/GB0118517D0/en not_active Ceased
-
2002
- 2002-07-29 CN CNB028192850A patent/CN100457088C/zh not_active Expired - Fee Related
- 2002-07-29 CA CA002451868A patent/CA2451868A1/en not_active Abandoned
- 2002-07-29 AU AU2002317402A patent/AU2002317402B2/en not_active Ceased
- 2002-07-29 EP EP02745690A patent/EP1411898A1/en not_active Withdrawn
- 2002-07-29 RU RU2004106154/15A patent/RU2294738C2/ru not_active IP Right Cessation
- 2002-07-29 WO PCT/GB2002/003488 patent/WO2003011252A1/en not_active Ceased
- 2002-07-29 US US10/484,855 patent/US20040219202A1/en not_active Abandoned
- 2002-07-29 JP JP2003516484A patent/JP2005505521A/ja active Pending
Non-Patent Citations (3)
| Title |
|---|
| Pisch et al. Tetrahedron (1997) vol. 53, no. 43 pages 14627-14634 * |
| Rurup et al. Chemistry and Physics of Lipids (1994) vol. 70, no. 2 pages 187-198 * |
| Stanish et al. Chemistry and Physics of Lipids (2001) vol. 112 pages 99-108 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005505521A (ja) | 2005-02-24 |
| WO2003011252A1 (en) | 2003-02-13 |
| RU2004106154A (ru) | 2005-05-10 |
| CA2451868A1 (en) | 2003-02-13 |
| CN1561199A (zh) | 2005-01-05 |
| GB0118517D0 (en) | 2001-09-19 |
| US20040219202A1 (en) | 2004-11-04 |
| EP1411898A1 (en) | 2004-04-28 |
| RU2294738C2 (ru) | 2007-03-10 |
| CN100457088C (zh) | 2009-02-04 |
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