AU2002257802B2 - Use of bisphosphonates in the treatment of bone metastasis associated with prostate cancer - Google Patents

Use of bisphosphonates in the treatment of bone metastasis associated with prostate cancer Download PDF

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Publication number
AU2002257802B2
AU2002257802B2 AU2002257802A AU2002257802A AU2002257802B2 AU 2002257802 B2 AU2002257802 B2 AU 2002257802B2 AU 2002257802 A AU2002257802 A AU 2002257802A AU 2002257802 A AU2002257802 A AU 2002257802A AU 2002257802 B2 AU2002257802 B2 AU 2002257802B2
Authority
AU
Australia
Prior art keywords
diphosphonic acid
acid
bisphosphonate
hydroxy
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002257802A
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English (en)
Other versions
AU2002257802A1 (en
Inventor
John J. Seaman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of AU2002257802A1 publication Critical patent/AU2002257802A1/en
Application granted granted Critical
Publication of AU2002257802B2 publication Critical patent/AU2002257802B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AU2002257802A 2001-05-02 2002-04-30 Use of bisphosphonates in the treatment of bone metastasis associated with prostate cancer Ceased AU2002257802B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28822001P 2001-05-02 2001-05-02
US60/288,220 2001-05-02
PCT/EP2002/004771 WO2002087555A2 (en) 2001-05-02 2002-04-30 Use of bisphosphonates in the treatment of bone metastasis associated with prostate cancer

Publications (2)

Publication Number Publication Date
AU2002257802A1 AU2002257802A1 (en) 2003-04-17
AU2002257802B2 true AU2002257802B2 (en) 2006-02-16

Family

ID=23106248

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002257802A Ceased AU2002257802B2 (en) 2001-05-02 2002-04-30 Use of bisphosphonates in the treatment of bone metastasis associated with prostate cancer

Country Status (21)

Country Link
US (1) US20040157799A1 (https=)
EP (1) EP1418897A2 (https=)
JP (1) JP2004528340A (https=)
KR (1) KR20040015230A (https=)
CN (1) CN1277545C (https=)
AR (1) AR033175A1 (https=)
AU (1) AU2002257802B2 (https=)
BR (1) BR0209365A (https=)
CA (1) CA2443625A1 (https=)
CZ (1) CZ20032950A3 (https=)
HU (1) HUP0400096A2 (https=)
IL (1) IL158273A0 (https=)
MX (1) MXPA03010007A (https=)
MY (1) MY141584A (https=)
NO (1) NO20034877L (https=)
NZ (1) NZ528676A (https=)
PL (1) PL363507A1 (https=)
RU (1) RU2297229C2 (https=)
SK (1) SK13512003A3 (https=)
WO (1) WO2002087555A2 (https=)
ZA (1) ZA200307666B (https=)

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RU2517135C2 (ru) * 2008-05-07 2014-05-27 Меррион Рисерч Iii Лимитед Композиции пептидов и способы их получения
RU2407746C2 (ru) * 2008-09-29 2010-12-27 ЗАО "Фарм-Синтез" Радиофармацевтическое средство для диагностики и лечения (терапии) костных поражений скелета и способ его получения
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US9169279B2 (en) 2009-07-31 2015-10-27 Thar Pharmaceuticals, Inc. Crystallization method and bioavailability
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EP2289900A1 (en) * 2009-08-26 2011-03-02 Humboldt Universität zu Berlin Bisphosphonates as inhibitors of acid sphingomyelinase
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Also Published As

Publication number Publication date
CN1277545C (zh) 2006-10-04
RU2297229C2 (ru) 2007-04-20
JP2004528340A (ja) 2004-09-16
US20040157799A1 (en) 2004-08-12
CA2443625A1 (en) 2002-11-07
ZA200307666B (en) 2004-05-05
PL363507A1 (en) 2004-11-29
IL158273A0 (en) 2004-05-12
NO20034877D0 (no) 2003-10-31
MXPA03010007A (es) 2004-02-12
SK13512003A3 (sk) 2004-08-03
WO2002087555A3 (en) 2004-02-05
AR033175A1 (es) 2003-12-03
CN1638778A (zh) 2005-07-13
BR0209365A (pt) 2004-06-08
NO20034877L (no) 2003-12-19
MY141584A (en) 2010-05-14
EP1418897A2 (en) 2004-05-19
NZ528676A (en) 2006-03-31
WO2002087555A2 (en) 2002-11-07
RU2003133773A (ru) 2005-02-10
HK1080711A1 (en) 2006-05-04
HUP0400096A2 (hu) 2004-04-28
CZ20032950A3 (cs) 2004-06-16
KR20040015230A (ko) 2004-02-18

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