AU2002246757B2 - Methods and compositions for treating periodontal disease - Google Patents

Methods and compositions for treating periodontal disease Download PDF

Info

Publication number
AU2002246757B2
AU2002246757B2 AU2002246757A AU2002246757A AU2002246757B2 AU 2002246757 B2 AU2002246757 B2 AU 2002246757B2 AU 2002246757 A AU2002246757 A AU 2002246757A AU 2002246757 A AU2002246757 A AU 2002246757A AU 2002246757 B2 AU2002246757 B2 AU 2002246757B2
Authority
AU
Australia
Prior art keywords
phenyl
cox
methyl
inhibitor
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002246757A
Other languages
English (en)
Other versions
AU2002246757A1 (en
Inventor
George D. Hartman
Gideon A. Rodan
Sevgi B. Rodan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU2002246757A1 publication Critical patent/AU2002246757A1/en
Application granted granted Critical
Publication of AU2002246757B2 publication Critical patent/AU2002246757B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Furan Compounds (AREA)
AU2002246757A 2001-01-03 2001-12-28 Methods and compositions for treating periodontal disease Ceased AU2002246757B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25944101P 2001-01-03 2001-01-03
US60/259,441 2001-01-03
PCT/US2001/049638 WO2002053099A2 (fr) 2001-01-03 2001-12-28 Methodes et compositions de traitement d'une parodontopathie

Publications (2)

Publication Number Publication Date
AU2002246757A1 AU2002246757A1 (en) 2003-01-23
AU2002246757B2 true AU2002246757B2 (en) 2006-02-02

Family

ID=22984959

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002246757A Ceased AU2002246757B2 (en) 2001-01-03 2001-12-28 Methods and compositions for treating periodontal disease

Country Status (5)

Country Link
EP (1) EP1349548A4 (fr)
JP (1) JP2004517853A (fr)
AU (1) AU2002246757B2 (fr)
CA (1) CA2432504A1 (fr)
WO (1) WO2002053099A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201305668D0 (en) 2013-03-28 2013-05-15 Glaxosmithkline Ip Dev Ltd Avs6 Integrin Antagonists
PT3050878T (pt) 2013-09-24 2021-12-02 Fujifilm Corp Novo composto contendo azoto ou seu sal, ou seu complexo de metal
GB201417094D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201417018D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201417011D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compounds
GB201417002D0 (en) 2014-09-26 2014-11-12 Glaxosmithkline Ip Dev Ltd Novel compound
GB201604680D0 (en) 2016-03-21 2016-05-04 Glaxosmithkline Ip Dev Ltd Chemical Compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5190981A (en) * 1989-08-17 1993-03-02 Sepracor Inc. Formulation containing S(+) enantiomer of flurbiprofen or ketoprofen and method of use for oral administration for prevention and treatment of bone loss associated with periodontal disease
US20020028798A1 (en) * 1995-12-12 2002-03-07 Omeros Medical Systems Irrigation solution and method for inhibition of pain and inflammation
US6048861A (en) * 1997-12-17 2000-04-11 Merck & Co., Inc. Integrin receptor antagonists
DK1040111T3 (da) * 1997-12-17 2005-10-10 Merck & Co Inc Integrinreceptorantagonister
US6017926A (en) * 1997-12-17 2000-01-25 Merck & Co., Inc. Integrin receptor antagonists
US6136804A (en) * 1998-03-13 2000-10-24 Merck & Co., Inc. Combination therapy for treating, preventing, or reducing the risks associated with acute coronary ischemic syndrome and related conditions
WO2000006169A1 (fr) * 1998-07-29 2000-02-10 Merck & Co., Inc. Antagonistes des recepteurs de l'integrine
PT1187592E (pt) * 1999-06-02 2007-10-19 Merck & Co Inc Antagonistas dos receptores de integrina alfa v

Also Published As

Publication number Publication date
JP2004517853A (ja) 2004-06-17
WO2002053099A2 (fr) 2002-07-11
CA2432504A1 (fr) 2002-07-11
EP1349548A2 (fr) 2003-10-08
WO2002053099A3 (fr) 2002-09-12
EP1349548A4 (fr) 2004-06-02

Similar Documents

Publication Publication Date Title
ES2234324T3 (es) Combinaciones de un agonista 5ht1b/1d y un inhibidor selectivo de cox-2 para el tratamiento de la migraña.
US6232315B1 (en) Method for treating inflammatory diseases by administering a thrombin inhibitor
KR100671392B1 (ko) 항균제로서의 화합물의 신규한 용도
EP1071430A1 (fr) Traitement de l'hypertension iatrogene et liee au vieillissement et compositions pharmaceutiques utiles a cet effet
US6413955B1 (en) Integrin receptor antagonists
NO321388B1 (no) Farmasoytisk sammensetning inneholdende en forbindelse med angiotensin II antagonistisk aktivitet i kombinasjon med en forbindelse som har insulinsensitivitetsstimulerende aktivitet, og anvendelse av samme for fremstilling av medikament.
JP2010523682A (ja) 癌及び他の疾患の治療に有用なカルボリン誘導体の投与
JP2006176542A (ja) フェニルエテンスルホンアミド誘導体含有医薬
ZA200110349B (en) Combination of tumors necrocis factor (TNF) antagonists and cox-2 inhibitors for the treatment of inflammation.
AU2002246757B2 (en) Methods and compositions for treating periodontal disease
US20040053968A1 (en) Methods and compositions for treating peridontal disease
US20020040039A1 (en) Treatment of inflammation with a combination of a cyclooxygenase-2 inhibitor and an integrin alpha-v antagonist
AU2002246757A1 (en) Methods and compositions for treating periodontal disease
JPH0489428A (ja) 多形核白血球活性化剤
JPH10511978A (ja) アルツハイマー病の治療用薬剤
US7358254B2 (en) Method for treating atherosclerosis employing an aP2 inhibitor and combination
JP2006509720A (ja) 潰瘍治療用プロトンポンプ阻害剤としての環付加ピロール化合物
JP6824015B2 (ja) 歯槽骨吸収抑制剤
WO2005020895A2 (fr) Methode de traitement ou de prevention des troubles osseux au moyen d'un inhibiteur de cyclooxygenase-2 seul ou en combinaison avec un agent de traitement des troubles osseux, et compositions associees
AU3948699A (en) Use of a cox-2 inhibitor and a nk-1 receptor antagonist for treating inflammation
JP2008285452A (ja) ＰＰＡＲα／γデュアルアゴニストおよび糖尿病治療薬を組み合わせてなる医薬
JP4677705B2 (ja) 頭痛の予防および／または治療剤
IL95880A (en) Use of 3-Transformed History of 2-Oxindole for the Preparation of Pharmaceuticals for Inhibition of Interlaukio-1 Biosynthesis
JPH0610133B2 (ja) 増殖過剰性皮膚疾患処置用組成物

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired