AU2002228783A1 - Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases - Google Patents

Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases

Info

Publication number
AU2002228783A1
AU2002228783A1 AU2002228783A AU2878302A AU2002228783A1 AU 2002228783 A1 AU2002228783 A1 AU 2002228783A1 AU 2002228783 A AU2002228783 A AU 2002228783A AU 2878302 A AU2878302 A AU 2878302A AU 2002228783 A1 AU2002228783 A1 AU 2002228783A1
Authority
AU
Australia
Prior art keywords
jnk
kinases
inhibitors
jun
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002228783A
Other languages
English (en)
Inventor
Mark Ledeboer
Young-Choon Moon
Francesco Salituro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vertex Pharmaceuticals Inc
Original Assignee
Vertex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vertex Pharmaceuticals Inc filed Critical Vertex Pharmaceuticals Inc
Publication of AU2002228783A1 publication Critical patent/AU2002228783A1/en
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
AU2002228783A 2000-12-05 2001-12-05 Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases Abandoned AU2002228783A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25140900P 2000-12-05 2000-12-05
US60251409 2000-12-05
PCT/US2001/046383 WO2002046184A1 (en) 2000-12-05 2001-12-05 Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases

Publications (1)

Publication Number Publication Date
AU2002228783A1 true AU2002228783A1 (en) 2002-06-18

Family

ID=22951847

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002228783A Abandoned AU2002228783A1 (en) 2000-12-05 2001-12-05 Inhibitors of c-jun n-terminal kinases (jnk) and other protein kinases

Country Status (10)

Country Link
US (1) US20020111353A1 (de)
EP (1) EP1343781B1 (de)
JP (2) JP4377583B2 (de)
AT (1) ATE407132T1 (de)
AU (1) AU2002228783A1 (de)
CA (1) CA2430539C (de)
DE (1) DE60135676D1 (de)
ES (1) ES2307667T3 (de)
MX (1) MXPA03005001A (de)
WO (1) WO2002046184A1 (de)

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EP2640723A1 (de) 2010-11-19 2013-09-25 Incyte Corporation Cyclobutyl-substituierte pyrrolopyridin- und pyrrolopyrimidinderivate als jak-inhibitoren
CN103237793B (zh) * 2010-12-01 2015-06-10 日产化学工业株式会社 具有多发性骨髓瘤的治疗效果的吡唑化合物
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