AU2002224416A1 - Compositions and methods for modulating RSV infection and immunity - Google Patents
Compositions and methods for modulating RSV infection and immunityInfo
- Publication number
- AU2002224416A1 AU2002224416A1 AU2002224416A AU2441602A AU2002224416A1 AU 2002224416 A1 AU2002224416 A1 AU 2002224416A1 AU 2002224416 A AU2002224416 A AU 2002224416A AU 2441602 A AU2441602 A AU 2441602A AU 2002224416 A1 AU2002224416 A1 AU 2002224416A1
- Authority
- AU
- Australia
- Prior art keywords
- glycoprotein
- rsv
- composition
- respiratory syncytial
- syncytial virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 238000000926 separation method Methods 0.000 description 1
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- CSRCBLMBBOJYEX-UHFFFAOYSA-M sodium;2-morpholin-4-ylethanesulfonic acid;hydroxide Chemical compound [OH-].[Na+].OS(=O)(=O)CCN1CCOCC1 CSRCBLMBBOJYEX-UHFFFAOYSA-M 0.000 description 1
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- 238000012453 sprague-dawley rat model Methods 0.000 description 1
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- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 229940021747 therapeutic vaccine Drugs 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- 229960002175 thyroglobulin Drugs 0.000 description 1
- 231100000583 toxicological profile Toxicity 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 230000009261 transgenic effect Effects 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 229950004616 tribromoethanol Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2009200997A AU2009200997B2 (en) | 2000-10-18 | 2009-03-12 | Compositions and methods for modulating RSV infection and immunity |
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| US24152100P | 2000-10-18 | 2000-10-18 | |
| US60/241,521 | 2000-10-18 | ||
| PCT/US2001/032459 WO2002032942A2 (en) | 2000-10-18 | 2001-10-18 | Compositions and methods for modulating rsv infection and immunity |
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| AU2002224416A1 true AU2002224416A1 (en) | 2002-04-29 |
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| AU2009200997A Expired AU2009200997B2 (en) | 2000-10-18 | 2009-03-12 | Compositions and methods for modulating RSV infection and immunity |
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| AU2009200997A Expired AU2009200997B2 (en) | 2000-10-18 | 2009-03-12 | Compositions and methods for modulating RSV infection and immunity |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US20040009177A1 (de) |
| EP (1) | EP1334119B2 (de) |
| AT (1) | ATE412666T1 (de) |
| AU (2) | AU2002224416A1 (de) |
| CA (1) | CA2426312C (de) |
| DE (1) | DE60136381D1 (de) |
| DK (1) | DK1334119T4 (de) |
| ES (1) | ES2316487T5 (de) |
| WO (1) | WO2002032942A2 (de) |
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| EP1768993A4 (de) * | 2004-06-16 | 2008-07-23 | Univ Johns Hopkins | Cysteinreiche region des humanen respiratorischen synzytial-virus und verwendungsverfahren dafür |
| US20100040606A1 (en) * | 2006-03-06 | 2010-02-18 | Symphogen A/S | Recombinant polyclonal antibody for treatment of respiratory syncytial virus infections |
| JP2010534057A (ja) * | 2007-03-06 | 2010-11-04 | シムフォゲン・アクティーゼルスカブ | 呼吸器合胞体ウイルス感染症を治療するための組換え抗体 |
| US7736648B2 (en) * | 2007-10-25 | 2010-06-15 | Trellis Bioscience, Inc. | Anti-RSV G protein antibodies |
| GB0724253D0 (en) * | 2007-12-12 | 2008-01-30 | Fermentas Uab | Transfection reagent |
| WO2009128949A2 (en) * | 2008-04-18 | 2009-10-22 | Vaxinnate Corporation | Compositions of dengue viral proteins and methods of use |
| US20110318376A1 (en) * | 2008-12-24 | 2011-12-29 | University Of Rochester | Recombinant expression of self-folding neutralizing epitope-bearing subdomains of the respiratory syncytial virus attachment and fusion proteins |
| EP2461825B1 (de) | 2009-08-04 | 2017-05-31 | The Government of The United States of America, as represented by the Secretary, Department of Health and Human Services, | Anti-rsv-immunogene und immunisierungsverfahren damit |
| GB0917792D0 (en) * | 2009-10-12 | 2009-11-25 | Fermentas Uab | Delivery agent |
| US9856456B2 (en) | 2009-10-12 | 2018-01-02 | Thermo Fisher Scientific Baltics Uab | Delivery agent |
| AU2011276251B2 (en) | 2010-07-07 | 2015-02-05 | Artifical Cell Technologies, Inc. | Respiratory syncytial virus antigenic compositions and methods |
| MY158978A (en) * | 2010-07-28 | 2016-11-30 | Nissan Motor | Bipolar electrode, bipolar secondary battery using the same and method for manufacturing bipolar electrode |
| EA201891945A3 (ru) | 2012-08-01 | 2019-05-31 | Бавариан Нордик А/С | Вакцина рекомбинантного модифицированного вируса осповакцины анкара (mva) респираторно-синцитиального вируса (rsv) |
| EP2993009A1 (de) * | 2014-09-08 | 2016-03-09 | HILTI Aktiengesellschaft | Verfahren zur Steuerung eines Wandsägesystems beim Erstellen eines Trennschnittes |
| SE539731C2 (sv) | 2016-03-04 | 2017-11-14 | Vertical Wind Ab | Rotor för en elektrisk generator och förfarande för dess tillverkning |
| JP7445895B2 (ja) * | 2017-10-13 | 2024-03-08 | トレリス・バイオサイエンス・インコーポレーテッド | 呼吸器合胞体ウイルスｇタンパク質中央保存領域の立体構造エピトープ |
| US11201095B1 (en) | 2019-08-23 | 2021-12-14 | Xilinx, Inc. | Chip package having a cover with window |
| WO2021194890A1 (en) * | 2020-03-23 | 2021-09-30 | Atossa Therapeutics, Inc. | Heparin and n-acetylcysteine for the treatment of a respiratory virus |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2718452B1 (fr) † | 1994-04-06 | 1996-06-28 | Pf Medicament | Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation. |
| AU710713B2 (en) | 1994-08-25 | 1999-09-30 | Stichting Instituut Voor Dierhouderij En Diergezondheid | Antigenic peptides derived from the G protein of RSV for type- and subtype-specific diagnosis of respiratory syncytial virus (RSV) infection |
| JPH11503030A (ja) † | 1996-01-24 | 1999-03-23 | シェーリング コーポレイション | 哺乳動物ｃｘ３ｃケモカイン遺伝子 |
| AUPO026596A0 (en) | 1996-06-05 | 1996-06-27 | Biomolecular Research Institute Limited | Viral peptide |
| US6020182A (en) * | 1996-07-12 | 2000-02-01 | Connaught Laboratories Limited | Subunit respiratory syncytial virus vaccine preparation |
| WO1999001433A1 (fr) | 1997-07-04 | 1999-01-14 | Chisso Corporation | Composes de type cristaux liquides dotes d'une valeur elevee d'anisotropie de permittivite, composition de cristaux liquides contenant ces composes et element d'affichage a cristaux liquides fabrique a partir d'une telle composition de cristaux liquides |
| WO1999014334A1 (en) | 1997-09-19 | 1999-03-25 | American Cyanamid Company | Peptides derived from the attachment (g) protein of respiratory syncytial virus |
| FR2827605B1 (fr) | 2001-07-20 | 2004-07-16 | Pf Medicament | Nouveaux peptides derives de la proteine g du vrs et leur utilisation dans un vaccin |
-
2001
- 2001-10-18 AU AU2002224416A patent/AU2002224416A1/en not_active Abandoned
- 2001-10-18 CA CA2426312A patent/CA2426312C/en not_active Expired - Lifetime
- 2001-10-18 AT AT01987765T patent/ATE412666T1/de not_active IP Right Cessation
- 2001-10-18 WO PCT/US2001/032459 patent/WO2002032942A2/en active Search and Examination
- 2001-10-18 EP EP01987765.3A patent/EP1334119B2/de not_active Expired - Lifetime
- 2001-10-18 DE DE60136381T patent/DE60136381D1/de not_active Expired - Lifetime
- 2001-10-18 DK DK01987765.3T patent/DK1334119T4/en active
- 2001-10-18 ES ES01987765T patent/ES2316487T5/es not_active Expired - Lifetime
-
2003
- 2003-04-18 US US10/420,387 patent/US20040009177A1/en not_active Abandoned
-
2005
- 2005-05-26 US US11/139,372 patent/US8173131B2/en not_active Expired - Fee Related
-
2009
- 2009-03-12 AU AU2009200997A patent/AU2009200997B2/en not_active Expired
-
2012
- 2012-01-25 US US13/358,320 patent/US8778354B2/en not_active Expired - Fee Related
-
2014
- 2014-04-15 US US14/252,836 patent/US20140288267A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009200997A1 (en) | 2009-04-02 |
| EP1334119A2 (de) | 2003-08-13 |
| CA2426312A1 (en) | 2002-04-25 |
| ATE412666T1 (de) | 2008-11-15 |
| US8173131B2 (en) | 2012-05-08 |
| US20140288267A1 (en) | 2014-09-25 |
| WO2002032942A3 (en) | 2002-12-12 |
| ES2316487T5 (es) | 2019-05-13 |
| US20060018925A1 (en) | 2006-01-26 |
| ES2316487T3 (es) | 2009-04-16 |
| WO2002032942A2 (en) | 2002-04-25 |
| DK1334119T3 (da) | 2009-02-23 |
| AU2009200997B2 (en) | 2011-12-22 |
| US20040009177A1 (en) | 2004-01-15 |
| CA2426312C (en) | 2014-01-14 |
| EP1334119B2 (de) | 2018-11-28 |
| US20120258111A1 (en) | 2012-10-11 |
| US8778354B2 (en) | 2014-07-15 |
| DE60136381D1 (de) | 2008-12-11 |
| EP1334119B1 (de) | 2008-10-29 |
| DK1334119T4 (en) | 2019-03-18 |
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