AU2002211862B2 - Methods of inducing cancer cell death and tumor regression - Google Patents
Methods of inducing cancer cell death and tumor regression Download PDFInfo
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- AU2002211862B2 AU2002211862B2 AU2002211862A AU2002211862A AU2002211862B2 AU 2002211862 B2 AU2002211862 B2 AU 2002211862B2 AU 2002211862 A AU2002211862 A AU 2002211862A AU 2002211862 A AU2002211862 A AU 2002211862A AU 2002211862 B2 AU2002211862 B2 AU 2002211862B2
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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| US23824000P | 2000-10-05 | 2000-10-05 | |
| US60/238,240 | 2000-10-05 | ||
| PCT/US2001/042509 WO2002028381A2 (en) | 2000-10-05 | 2001-10-05 | Methods of inducing cancer cell death and tumor regression |
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| AU2002211862A1 AU2002211862A1 (en) | 2002-06-27 |
| AU2002211862B2 true AU2002211862B2 (en) | 2007-03-15 |
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| AU2002211862A Ceased AU2002211862B2 (en) | 2000-10-05 | 2001-10-05 | Methods of inducing cancer cell death and tumor regression |
| AU1186202A Pending AU1186202A (en) | 2000-10-05 | 2001-10-05 | Methods of inducing cancer cell death and tumor regression |
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| AU1186202A Pending AU1186202A (en) | 2000-10-05 | 2001-10-05 | Methods of inducing cancer cell death and tumor regression |
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| US (1) | US6777415B2 (https=) |
| EP (1) | EP1322334A2 (https=) |
| JP (1) | JP2004510733A (https=) |
| CN (1) | CN1479630A (https=) |
| AU (2) | AU2002211862B2 (https=) |
| BR (1) | BR0114430A (https=) |
| CA (1) | CA2424797C (https=) |
| HK (1) | HK1052870A1 (https=) |
| HU (1) | HUP0302913A3 (https=) |
| MX (1) | MXPA03003011A (https=) |
| NO (1) | NO20031531L (https=) |
| NZ (1) | NZ524936A (https=) |
| WO (1) | WO2002028381A2 (https=) |
| ZA (1) | ZA200302523B (https=) |
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| US6369138B2 (en) | 1997-07-11 | 2002-04-09 | Bridgestone Corporation | Processability of silica-filled rubber stocks with reduced hysteresis |
| WO2008109417A1 (en) * | 2007-03-02 | 2008-09-12 | Case Western Reserve University | Mgmt inhibitor combinations for the treatment of neoplastic disorders |
| US20020077301A1 (en) * | 2000-10-05 | 2002-06-20 | Whitehead Institute For Biomedical Research | Effects of combined administration of farnesyl transferase inhibitors and signal transduction inhibitors |
| US20040126755A1 (en) * | 2001-08-29 | 2004-07-01 | Stephan Dietrich A | Gene expression based method for distinguishing metastatic from non-metastatic forms of a tumor, and use in designing therapeutic drugs |
| CN1617755A (zh) * | 2001-11-30 | 2005-05-18 | 先灵公司 | 法尼基蛋白转移酶抑制剂和其它抗肿瘤剂联合使用在制备抗癌症的药物中的应用 |
| CA2468996A1 (en) * | 2001-12-03 | 2003-06-12 | Schering Corporation | Use of fpt inhibitors and at least two antineoplastic agents in the treatment of cancer |
| EP1654377A4 (en) * | 2002-03-01 | 2010-03-24 | Roger Williams Hospital | PROCESSES AND COMPOSITIONS RELATED TO THE SHC PROTEIN FOR THE PROGNOSIS OF BREAST, PROSTATE AND EGG CANCER |
| US20050004008A1 (en) * | 2002-03-01 | 2005-01-06 | Frackelton A. Raymond | SHC proteins as therapeutic targets in proliferative diseases |
| US20050101576A1 (en) * | 2003-11-06 | 2005-05-12 | Novacea, Inc. | Methods of using vitamin D compounds in the treatment of myelodysplastic syndromes |
| US7691905B2 (en) * | 2002-12-24 | 2010-04-06 | New York University | Inhibition of melanogenesis and melanoma metastasis with p-aminobenzoic acid (PABA) |
| CA2544421A1 (en) * | 2003-11-06 | 2005-05-26 | Schering Corporation | Combination of a farnesyl transferase inhibitor with an antihormonal agent for the treatment of breast cancer |
| US20060205810A1 (en) * | 2004-11-24 | 2006-09-14 | Schering Corporation | Platinum therapeutic combinations |
| US20070148660A1 (en) * | 2005-06-16 | 2007-06-28 | The Regents Of The University Of California | Treatment of maladaptive substance use with H-ras antagonists |
| US20080255171A1 (en) * | 2005-10-07 | 2008-10-16 | Manley Paul W | Combination of Nilotinib with Farnesyl Transferase Inhibitors |
| JP2009516167A (ja) * | 2005-11-11 | 2009-04-16 | ロジャー・ウィリアムズ・ホスピタル | 癌処置における予測マーカーとしてのｐ６６−ｓｈｃ |
| CN102274513B (zh) * | 2011-07-06 | 2013-02-20 | 南开大学 | ERK1/2抑制剂通过刺激巨噬细胞干扰素γ表达抑制肿瘤生长 |
| CN102626416B (zh) * | 2012-05-11 | 2013-04-17 | 江苏省人民医院 | 他莫昔芬联合雷帕霉素、人参皂苷Rg3复合物在制备治疗肝癌药物中的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1997045412A1 (en) * | 1996-05-30 | 1997-12-04 | Merck & Co., Inc. | A method of treating cancer |
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| WO1992011034A1 (en) | 1990-12-18 | 1992-07-09 | The Wellcome Foundation Limited | Agents for potentiating the effects of antitumor agents and combating multiple drug resistance |
| US5874442A (en) | 1995-12-22 | 1999-02-23 | Schering-Plough Corporation | Tricyclic amides useful for inhibition of G-protein function and for treatment of proliferative disease |
| CA2250232A1 (en) | 1996-04-03 | 1997-10-09 | Allen I. Oliff | A method of treating cancer |
| CA2293433C (en) * | 1997-06-17 | 2009-09-29 | Schering Corporation | Benzo(5,6)cyclohepta(1,2-b)pyridine derivatives as farnesyl protein transferase inhibitors |
| ZA985205B (en) * | 1997-06-17 | 1998-12-15 | Schering Corp | Novel n-substituted urea inhibitors of arnesyl-protein transferase |
| US6096757A (en) | 1998-12-21 | 2000-08-01 | Schering Corporation | Method for treating proliferative diseases |
| US6383790B1 (en) | 1999-01-11 | 2002-05-07 | Princeton University | High affinity protein kinase inhibitors |
| US6316462B1 (en) | 1999-04-09 | 2001-11-13 | Schering Corporation | Methods of inducing cancer cell death and tumor regression |
| DE60031268T2 (de) * | 1999-04-14 | 2007-05-24 | Dana-Farber Cancer Institute, Inc., Boston | Verfahren und zusammansetzung zur behandlung von krebs |
| US6465448B1 (en) * | 1999-08-13 | 2002-10-15 | Case Western Reserve University | Methoxyamine potentiation of temozolomide anti-cancer activity |
| WO2002000024A1 (en) * | 2000-06-30 | 2002-01-03 | The Regents Of The University Of California | New strategy for leukemia therapy |
| US20020077301A1 (en) * | 2000-10-05 | 2002-06-20 | Whitehead Institute For Biomedical Research | Effects of combined administration of farnesyl transferase inhibitors and signal transduction inhibitors |
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2001
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997045412A1 (en) * | 1996-05-30 | 1997-12-04 | Merck & Co., Inc. | A method of treating cancer |
Also Published As
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| NO20031531D0 (no) | 2003-04-04 |
| HUP0302913A2 (hu) | 2003-12-29 |
| CN1479630A (zh) | 2004-03-03 |
| JP2004510733A (ja) | 2004-04-08 |
| MXPA03003011A (es) | 2003-07-14 |
| HUP0302913A3 (en) | 2005-05-30 |
| NO20031531L (no) | 2003-06-05 |
| WO2002028381A3 (en) | 2003-03-27 |
| AU1186202A (en) | 2002-04-15 |
| HK1052870A1 (zh) | 2003-10-03 |
| EP1322334A2 (en) | 2003-07-02 |
| US6777415B2 (en) | 2004-08-17 |
| NZ524936A (en) | 2005-08-26 |
| BR0114430A (pt) | 2004-01-06 |
| US20020128280A1 (en) | 2002-09-12 |
| CA2424797C (en) | 2009-12-29 |
| WO2002028381A2 (en) | 2002-04-11 |
| CA2424797A1 (en) | 2002-04-11 |
| ZA200302523B (en) | 2004-08-24 |
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