AU2001293229B2 - Thrombomodulin analogs for use in recovery of spinal cord injury - Google Patents

Thrombomodulin analogs for use in recovery of spinal cord injury Download PDF

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Publication number
AU2001293229B2
AU2001293229B2 AU2001293229A AU2001293229A AU2001293229B2 AU 2001293229 B2 AU2001293229 B2 AU 2001293229B2 AU 2001293229 A AU2001293229 A AU 2001293229A AU 2001293229 A AU2001293229 A AU 2001293229A AU 2001293229 B2 AU2001293229 B2 AU 2001293229B2
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AU
Australia
Prior art keywords
thrombomodulin
human
pharmaceutical composition
analog
thrombomodulin analog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2001293229A
Other languages
English (en)
Other versions
AU2001293229A1 (en
Inventor
Barry W. Festoff
Michael John Morser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Paion Deutschland GmbH
Original Assignee
Paion Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paion Deutschland GmbH filed Critical Paion Deutschland GmbH
Publication of AU2001293229A1 publication Critical patent/AU2001293229A1/en
Assigned to PAION DEUTSCHLAND GMBH reassignment PAION DEUTSCHLAND GMBH Request for Assignment Assignors: SCHERING AKTIENGESELLESCHAFT
Application granted granted Critical
Publication of AU2001293229B2 publication Critical patent/AU2001293229B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/366Thrombomodulin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Accommodation For Nursing Or Treatment Tables (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Communication Cables (AREA)
  • Signal Processing Not Specific To The Method Of Recording And Reproducing (AREA)
  • Ropes Or Cables (AREA)
AU2001293229A 2000-08-31 2001-08-31 Thrombomodulin analogs for use in recovery of spinal cord injury Ceased AU2001293229B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US22971400P 2000-08-31 2000-08-31
US60/229,714 2000-08-31
US09/938,405 2001-08-23
US09/938,405 US20020111296A1 (en) 2000-08-31 2001-08-23 Thrombomodulin analogs for use in recovery of spinal cord injury
PCT/US2001/041930 WO2002017953A2 (en) 2000-08-31 2001-08-31 Thrombomodulin analogs for use in recovery of signal cord injury

Publications (2)

Publication Number Publication Date
AU2001293229A1 AU2001293229A1 (en) 2002-06-06
AU2001293229B2 true AU2001293229B2 (en) 2007-04-05

Family

ID=26923554

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2001293229A Ceased AU2001293229B2 (en) 2000-08-31 2001-08-31 Thrombomodulin analogs for use in recovery of spinal cord injury
AU9322901A Pending AU9322901A (en) 2000-08-31 2001-08-31 Thrombomodulin analogs for use in recovery of signal cord injury

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU9322901A Pending AU9322901A (en) 2000-08-31 2001-08-31 Thrombomodulin analogs for use in recovery of signal cord injury

Country Status (13)

Country Link
US (3) US20020111296A1 (OSRAM)
EP (1) EP1365788B1 (OSRAM)
JP (1) JP2004521076A (OSRAM)
AT (1) ATE361755T1 (OSRAM)
AU (2) AU2001293229B2 (OSRAM)
CA (1) CA2420900A1 (OSRAM)
DE (1) DE60128399T2 (OSRAM)
DK (1) DK1365788T3 (OSRAM)
ES (1) ES2287161T3 (OSRAM)
IL (2) IL154600A0 (OSRAM)
NO (1) NO20030919L (OSRAM)
PT (1) PT1365788E (OSRAM)
WO (1) WO2002017953A2 (OSRAM)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006005362A1 (en) * 2004-07-13 2006-01-19 Paion Deutschland Gmbh Production of mammalian proteins in plant cells
US8293710B2 (en) * 2005-01-03 2012-10-23 Blue Blood Biotech Corp. Method for treating wounds using an EGF-like domain of thrombomodulin
US20060148695A1 (en) * 2005-01-03 2006-07-06 National Cheng Kung University Novel angiogenic composition and use thereof
EP1912660A1 (en) * 2005-08-11 2008-04-23 Medigenes Co., Ltd. Pharmaceutical composition for the treatment of nerve damage comprising blood plasma or serum
EP2014296A1 (en) * 2007-07-10 2009-01-14 PAION Deutschland GmbH Novel strategies for increasing the reperfusion in obstructed blood vessel
AR067345A1 (es) * 2007-07-10 2009-10-07 Paion Deutschland Gmbh Uso de trombomodulina para la preparacion de un medicamento trombolitico
EP2320936A1 (en) * 2008-07-16 2011-05-18 PAION Deutschland GmbH Prevention and treatment of radiation injury
WO2010006635A1 (en) * 2008-07-16 2010-01-21 Paion Deutschland Gmbh Treatment of inflammatory bowel disease
PT2857037T (pt) 2012-05-31 2019-07-19 Univ Kinki Agente para prevenção e/ou tratamento de dor neuropática periférica causada por fármaco anticanceroso
MX2021003288A (es) * 2018-09-28 2021-05-13 Asahi Kasei Pharma Corp Medicacion para aliviar los sintomas de la neuropatia periferica causada por farmacos anticancerigenos y/o suprimir el inicio de la neuropatia periferica.
US11497795B2 (en) 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256770A (en) * 1990-04-09 1993-10-26 Schering Ag Oxidation resistant thrombomodulin analogs
JPH08283174A (ja) * 1995-04-11 1996-10-29 Asahi Chem Ind Co Ltd 脊髄損傷後の神経障害に対する治療剤
US5863760A (en) * 1989-04-28 1999-01-26 Schering Altiengesellschaft Protease-resistant thrombomodulin analogs

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466668A (en) * 1989-04-28 1995-11-14 Schering Aktiengesellschaft Superior thrombomodulin analogs for pharmaceutical use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863760A (en) * 1989-04-28 1999-01-26 Schering Altiengesellschaft Protease-resistant thrombomodulin analogs
US5256770A (en) * 1990-04-09 1993-10-26 Schering Ag Oxidation resistant thrombomodulin analogs
JPH08283174A (ja) * 1995-04-11 1996-10-29 Asahi Chem Ind Co Ltd 脊髄損傷後の神経障害に対する治療剤

Also Published As

Publication number Publication date
DE60128399T2 (de) 2008-01-10
EP1365788A2 (en) 2003-12-03
NO20030919D0 (no) 2003-02-27
DE60128399D1 (de) 2007-06-21
US20040002446A1 (en) 2004-01-01
CA2420900A1 (en) 2002-03-07
WO2002017953A3 (en) 2003-10-09
NO20030919L (no) 2003-04-10
AU9322901A (en) 2002-03-13
ATE361755T1 (de) 2007-06-15
US20090143281A1 (en) 2009-06-04
IL154600A (en) 2009-02-11
DK1365788T3 (da) 2007-09-17
EP1365788B1 (en) 2007-05-09
JP2004521076A (ja) 2004-07-15
WO2002017953A2 (en) 2002-03-07
PT1365788E (pt) 2007-08-10
US20020111296A1 (en) 2002-08-15
ES2287161T3 (es) 2007-12-16
HK1062398A1 (en) 2004-11-05
IL154600A0 (en) 2003-09-17

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Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: PAION DEUTSCHLAND GMBH

Free format text: FORMER APPLICANT(S): SCHERING AKTIENGESELLESCHAFT

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired