AU2001288053A1 - N-substituted benzothiophenesulfonamide derivatives - Google Patents
N-substituted benzothiophenesulfonamide derivativesInfo
- Publication number
- AU2001288053A1 AU2001288053A1 AU2001288053A AU8805301A AU2001288053A1 AU 2001288053 A1 AU2001288053 A1 AU 2001288053A1 AU 2001288053 A AU2001288053 A AU 2001288053A AU 8805301 A AU8805301 A AU 8805301A AU 2001288053 A1 AU2001288053 A1 AU 2001288053A1
- Authority
- AU
- Australia
- Prior art keywords
- agent
- substituted benzothiophenesulfonamide
- substituted
- chymase
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000282046 | 2000-09-18 | ||
JP2000-282046 | 2000-09-18 | ||
JP2001122972 | 2001-04-20 | ||
JP2001-122972 | 2001-04-20 | ||
PCT/JP2001/008061 WO2002022595A1 (fr) | 2000-09-18 | 2001-09-17 | Derives de benzothiophenesulfonamide substitue en n |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001288053A1 true AU2001288053A1 (en) | 2002-03-26 |
Family
ID=26600125
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001288053A Abandoned AU2001288053A1 (en) | 2000-09-18 | 2001-09-17 | N-substituted benzothiophenesulfonamide derivatives |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1325920B1 (fr) |
JP (1) | JP3847711B2 (fr) |
CN (1) | CN1245400C (fr) |
AT (1) | ATE478857T1 (fr) |
AU (1) | AU2001288053A1 (fr) |
CA (1) | CA2422807C (fr) |
DE (1) | DE60142914D1 (fr) |
WO (1) | WO2002022595A1 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003335670A (ja) * | 2002-03-15 | 2003-11-25 | Toa Eiyo Ltd | 癒着防止剤 |
DE60333351D1 (de) * | 2002-03-15 | 2010-08-26 | Toa Eiyo Ltd | N-substituiertes benzothiophensulfonamidderivat |
AU2004266536A1 (en) * | 2003-08-22 | 2005-03-03 | Teijin Pharma Limited | Drug containing chymase inhibitor as the active ingredient |
EP2118062A1 (fr) * | 2007-01-10 | 2009-11-18 | F. Hoffmann-Roche AG | Dérivés de sulfonamide en tant qu'inhibiteurs de la chymase |
US20090163586A1 (en) | 2007-12-20 | 2009-06-25 | Astrazeneca Ab | Bis-(Sulfonylamino) Derivatives in Therapy 205 |
EP2651957B1 (fr) * | 2010-12-16 | 2015-02-18 | Allergan, Inc. | Dérivés phosphoreux en tant que modulateurs de récepteur de chimiokine |
WO2014159657A1 (fr) | 2013-03-12 | 2014-10-02 | Allergan, Inc. | Dérivés de pyridinyl- et pyrimidinyl-sulfonamide en tant que modulateurs de récepteurs de chimiokine. |
WO2015084869A1 (fr) | 2013-12-02 | 2015-06-11 | Allergan, Inc. | Dérivés de benzothiophène-sulfonamides utilisés comme modulateurs des récepteurs des chimiokines |
CN111285844B (zh) * | 2020-02-24 | 2022-08-12 | 河南师范大学 | 具有生物活性的苯并噻吩取代酰胺类化合物及其合成方法和应用 |
TW202404601A (zh) | 2022-04-05 | 2024-02-01 | 加拿大商索科普拉健康與人類科學兩合公司 | 用於選擇性消退血栓性或血栓栓塞性疾病中血栓的凝乳酶抑制劑 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ299246B6 (cs) * | 1995-04-04 | 2008-05-28 | Encysive Pharmaceuticals Inc. | Sulfonamid, farmaceutická kompozice s jeho obsahem a jeho použití pro výrobu léciva |
WO1997011941A1 (fr) * | 1995-09-28 | 1997-04-03 | Suntory Limited | Derives de la quinazoline et leurs emplois |
DZ2376A1 (fr) * | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
GB9801392D0 (en) * | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
GB9803411D0 (en) * | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
JP2000095770A (ja) * | 1998-07-22 | 2000-04-04 | Toa Eiyo Ltd | N置換チアゾリジン誘導体及びそれを含有する医薬 |
HUP0103387A3 (en) * | 1998-08-21 | 2002-07-29 | Daiichi Asubio Pharma Co Ltd | Quinazoline derivatives preparation thereof, medicament containing them and their intermediates |
GB9818914D0 (en) * | 1998-08-28 | 1998-10-21 | Smithkline Beecham Plc | Use |
GB9818916D0 (en) * | 1998-08-28 | 1998-10-21 | Smithkline Beecham Plc | Use |
JP4491866B2 (ja) * | 1999-09-30 | 2010-06-30 | 三菱化学株式会社 | アシルスルホンアミド誘導体 |
-
2001
- 2001-09-17 EP EP01967708A patent/EP1325920B1/fr not_active Expired - Lifetime
- 2001-09-17 CN CNB01815851XA patent/CN1245400C/zh not_active Expired - Fee Related
- 2001-09-17 WO PCT/JP2001/008061 patent/WO2002022595A1/fr active Application Filing
- 2001-09-17 AU AU2001288053A patent/AU2001288053A1/en not_active Abandoned
- 2001-09-17 DE DE60142914T patent/DE60142914D1/de not_active Expired - Lifetime
- 2001-09-17 AT AT01967708T patent/ATE478857T1/de not_active IP Right Cessation
- 2001-09-17 CA CA002422807A patent/CA2422807C/fr not_active Expired - Fee Related
- 2001-09-17 JP JP2002526848A patent/JP3847711B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE478857T1 (de) | 2010-09-15 |
WO2002022595A1 (fr) | 2002-03-21 |
CA2422807A1 (fr) | 2003-03-18 |
EP1325920A1 (fr) | 2003-07-09 |
CA2422807C (fr) | 2009-12-08 |
JPWO2002022595A1 (ja) | 2004-01-22 |
CN1245400C (zh) | 2006-03-15 |
EP1325920B1 (fr) | 2010-08-25 |
JP3847711B2 (ja) | 2006-11-22 |
EP1325920A4 (fr) | 2005-02-02 |
CN1458928A (zh) | 2003-11-26 |
DE60142914D1 (de) | 2010-10-07 |
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