AU2001271669A1 - Multipartite high-affinity nucleic acid probes - Google Patents
Multipartite high-affinity nucleic acid probesInfo
- Publication number
- AU2001271669A1 AU2001271669A1 AU2001271669A AU7166901A AU2001271669A1 AU 2001271669 A1 AU2001271669 A1 AU 2001271669A1 AU 2001271669 A AU2001271669 A AU 2001271669A AU 7166901 A AU7166901 A AU 7166901A AU 2001271669 A1 AU2001271669 A1 AU 2001271669A1
- Authority
- AU
- Australia
- Prior art keywords
- multipartite
- nucleic acid
- acid probes
- affinity nucleic
- affinity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 108020004711 Nucleic Acid Probes Proteins 0.000 title 1
- 239000002853 nucleic acid probe Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/610,155 | 2000-06-30 | ||
US09/610,155 US6451588B1 (en) | 2000-06-30 | 2000-06-30 | Multipartite high-affinity nucleic acid probes |
PCT/US2001/020815 WO2002002817A2 (en) | 2000-06-30 | 2001-06-29 | Multipartite high-affinity nucleic acid probes |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001271669A1 true AU2001271669A1 (en) | 2002-01-14 |
Family
ID=24443889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001271669A Abandoned AU2001271669A1 (en) | 2000-06-30 | 2001-06-29 | Multipartite high-affinity nucleic acid probes |
Country Status (3)
Country | Link |
---|---|
US (2) | US6451588B1 (en) |
AU (1) | AU2001271669A1 (en) |
WO (1) | WO2002002817A2 (en) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030165888A1 (en) | 2001-07-18 | 2003-09-04 | Brown Bob D. | Oligonucleotide probes and primers comprising universal bases for diagnostic purposes |
US6518017B1 (en) * | 1997-10-02 | 2003-02-11 | Oasis Biosciences Incorporated | Combinatorial antisense library |
PT1171634E (en) * | 1999-04-08 | 2006-05-31 | Gen Probe Inc | PAIRS OF AMPLIFICATION AND SEQUENCING INITIATORS AND THEIR UTILIZATION |
US20030082549A1 (en) * | 2000-08-30 | 2003-05-01 | Xiangjun Liu | Method for determining alleles |
US6815164B2 (en) * | 2000-10-06 | 2004-11-09 | Nugen Technologies, Inc. | Methods and probes for detection and/or quantification of nucleic acid sequences |
DE10056802B4 (en) * | 2000-11-14 | 2005-06-16 | Epigenomics Ag | Method for the detection of methylation conditions for toxicological diagnostics |
US20040161741A1 (en) * | 2001-06-30 | 2004-08-19 | Elazar Rabani | Novel compositions and processes for analyte detection, quantification and amplification |
US9777312B2 (en) * | 2001-06-30 | 2017-10-03 | Enzo Life Sciences, Inc. | Dual polarity analysis of nucleic acids |
US9261460B2 (en) | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
US9353405B2 (en) | 2002-03-12 | 2016-05-31 | Enzo Life Sciences, Inc. | Optimized real time nucleic acid detection processes |
US20040137469A1 (en) * | 2002-09-08 | 2004-07-15 | Casale Ralph A | Methods, compositions and libraries pertaining PNA dimer and PNA oligomer synthesis |
WO2004069850A2 (en) * | 2003-02-04 | 2004-08-19 | Borer Philip N | Switchable nucleic acids for diagnostics, screening and molecular electronics |
US8003374B2 (en) | 2003-03-25 | 2011-08-23 | The Regents Of The University Of California | Reagentless, reusable, bioelectronic detectors |
US20040191801A1 (en) * | 2003-03-25 | 2004-09-30 | Heeger Alan J. | Reagentless, reusable bioelectronic detectors and their use as authentication devices |
CN101208437B (en) * | 2003-12-12 | 2012-07-04 | 圣路易斯大学 | Biosensors for detecting macromolecules and other analytes |
ATE466107T1 (en) | 2004-07-01 | 2010-05-15 | Gen Probe Inc | METHODS AND COMPOSITIONS FOR DETECTING NUCLEIC ACIDS IN A BIOLOGICAL SAMPLE |
AU2005324436B2 (en) * | 2004-08-03 | 2009-05-28 | Syracuse University | Branched and multi-chain nucleic acid switches for sensing and screening |
KR20070083924A (en) * | 2004-11-19 | 2007-08-24 | 와쿠나가 세이야쿠 가부시키 가이샤 | Nucleic acid fragments for detecting nucleic acid and method of detecting nucleic acid |
JP2006166911A (en) * | 2004-11-19 | 2006-06-29 | Wakunaga Pharmaceut Co Ltd | Nucleic acid fragment for detecting nucleic acid and method of detecting nucleic acid |
US8956857B2 (en) | 2005-06-06 | 2015-02-17 | Mediomics, Llc | Three-component biosensors for detecting macromolecules and other analytes |
US7795009B2 (en) * | 2005-06-15 | 2010-09-14 | Saint Louis University | Three-component biosensors for detecting macromolecules and other analytes |
WO2006135527A2 (en) * | 2005-06-10 | 2006-12-21 | Saint Louis University | Methods for the selection of aptamers |
US20060281100A1 (en) * | 2005-06-14 | 2006-12-14 | Shen Gene G | Thiotriphosphate nucleotide dye terminators |
US7811809B2 (en) * | 2005-06-15 | 2010-10-12 | Saint Louis University | Molecular biosensors for use in competition assays |
US8481697B2 (en) * | 2005-07-01 | 2013-07-09 | Dako Denmark A/S | Nucleic acid base pairs |
US7803542B2 (en) * | 2005-11-29 | 2010-09-28 | The Regents Of The University Of California | Signal-on architecture for electronic, oligonucleotide-based detectors |
WO2007101075A2 (en) * | 2006-02-22 | 2007-09-07 | Applera Corporation | Double-ligation method for haplotype and large-scale polymorphism detection |
US20100003679A1 (en) * | 2006-06-09 | 2010-01-07 | University Of Miami | Assessment of cellular composition and fractional viability and uses thereof |
EP2288726B1 (en) * | 2008-05-13 | 2012-06-13 | Gen-Probe Incorporated | Inactivatable target capture oligomers for use in the selective hybridization and capture of target nucleic acid sequences |
US8551767B2 (en) * | 2008-11-20 | 2013-10-08 | Agency Of Science, Technology And Research | Sensor for detection of nucleic acid |
EP2350657A4 (en) | 2008-11-21 | 2013-06-12 | Univ Saint Louis | Biosensor for detecting multiple epitopes on a target |
JP2012509675A (en) | 2008-11-25 | 2012-04-26 | ジェン−プロウブ インコーポレイテッド | Compositions and methods for detecting small RNAs and uses thereof |
US8409802B2 (en) * | 2009-08-14 | 2013-04-02 | Roche Molecular Systems, Inc. | Format of probes to detect nucleic acid differences |
EP2534266B1 (en) | 2010-02-12 | 2016-07-06 | Saint Louis University | Molecular biosensors capable of signal amplification |
US20120258870A1 (en) * | 2010-11-22 | 2012-10-11 | The University Of Chicago | Methods, Systems, and/or Use of Oligonucleotide Conjugates to Develop Panels for Use in Assays and Detections |
US20140186844A1 (en) * | 2011-04-26 | 2014-07-03 | Swift Biosciences, Inc. | Polynucleotide primers and probes |
EP2875132A4 (en) * | 2012-07-17 | 2016-02-24 | Dna Logix Inc | Cooperative primers, probes, and applications thereof |
US20140038182A1 (en) | 2012-07-17 | 2014-02-06 | Dna Logix, Inc. | Cooperative primers, probes, and applications thereof |
WO2014145620A2 (en) * | 2013-03-15 | 2014-09-18 | The Broad Institute, Inc. | Novel hybridization probes and uses thereof |
JP6475718B2 (en) | 2013-07-30 | 2019-02-27 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Quantitative DNA-based imaging and super-resolution imaging |
US10274484B2 (en) | 2014-09-12 | 2019-04-30 | Mediomics Llc | Molecular biosensors with a modular design |
US20170349940A1 (en) * | 2014-09-26 | 2017-12-07 | Two Pore Guys, Inc. | Targeted Sequence Detection by Nanopore Sensing of Synthetic Probes |
US10036066B2 (en) | 2015-03-17 | 2018-07-31 | Dako Denmark A/S | In situ hybridization detection method |
WO2017004243A1 (en) * | 2015-06-29 | 2017-01-05 | Caris Science, Inc. | Therapeutic oligonucleotides |
US11092606B2 (en) * | 2015-08-07 | 2021-08-17 | President And Fellows Of Harvard College | Super resolution imaging of protein-protein interactions |
CA2997120A1 (en) * | 2015-09-03 | 2017-03-09 | Nanostring Technologies, Inc. | Multivalent probes having single nucleotide resolution |
US11486873B2 (en) | 2016-03-31 | 2022-11-01 | Ontera Inc. | Multipore determination of fractional abundance of polynucleotide sequences in a sample |
US10871485B2 (en) | 2018-04-13 | 2020-12-22 | Rarecyte, Inc. | Kits for labeling of biomarkers and methods of using the same |
CA3114004A1 (en) * | 2018-09-25 | 2020-04-02 | Co-Diagnostics, Inc. | Allele-specific design of cooperative primers for improved nucleic acid variant genotyping |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989011211A2 (en) * | 1988-05-24 | 1989-11-30 | Gesellschaft Für Biotechnologische Forschung Mbh ( | Oligonucleotide bank and process for dna sequencing |
CA2036337C (en) * | 1990-02-15 | 2003-04-15 | Francois Clemence | Derivatives of 20,21-dinoreburnamenin, their preparation process and the new intermediates thus obtained, their application as drugs and the compositions containing such |
US5695926A (en) * | 1990-06-11 | 1997-12-09 | Bio Merieux | Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support |
US6140490A (en) * | 1996-02-01 | 2000-10-31 | Nexstar Pharmaceuticals, Inc. | High affinity nucleic acid ligands of complement system proteins |
US5424413A (en) * | 1992-01-22 | 1995-06-13 | Gen-Probe Incorporated | Branched nucleic acid probes |
US5663062A (en) | 1992-04-03 | 1997-09-02 | Stratagene | Oligonucleotide libraries useful for producing primers |
DE4344742A1 (en) | 1993-06-09 | 1994-12-15 | Boehringer Mannheim Gmbh | Method for the immobilization of nucleic acids |
US5861242A (en) * | 1993-06-25 | 1999-01-19 | Affymetrix, Inc. | Array of nucleic acid probes on biological chips for diagnosis of HIV and methods of using the same |
US5527675A (en) * | 1993-08-20 | 1996-06-18 | Millipore Corporation | Method for degradation and sequencing of polymers which sequentially eliminate terminal residues |
US5854410A (en) | 1994-03-31 | 1998-12-29 | Genta Incorporated | Oligonucleoside cleavage compounds and therapies |
US5821060A (en) | 1996-08-02 | 1998-10-13 | Atom Sciences, Inc. | DNA sequencing, mapping, and diagnostic processes using hybridization chips and unlabeled DNA |
US5935791A (en) | 1997-09-23 | 1999-08-10 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
WO1999022018A2 (en) * | 1997-10-27 | 1999-05-06 | Boston Probes, Inc. | Methods, kits and compositions pertaining to pna molecular beacons |
DE1051515T1 (en) | 1998-01-27 | 2001-04-19 | Cytocell Ltd | MODIFIED NUCLEIC ACID PROBES AND THEIR USE |
WO1999049293A2 (en) * | 1998-03-24 | 1999-09-30 | Boston Probes, Inc. | Methods, kits and compositions pertaining to detection complexes |
US6287772B1 (en) * | 1998-04-29 | 2001-09-11 | Boston Probes, Inc. | Methods, kits and compositions for detecting and quantitating target sequences |
US6255476B1 (en) * | 1999-02-22 | 2001-07-03 | Pe Corporation (Ny) | Methods and compositions for synthesis of labelled oligonucleotides and analogs on solid-supports |
-
2000
- 2000-06-30 US US09/610,155 patent/US6451588B1/en not_active Expired - Lifetime
-
2001
- 2001-06-29 WO PCT/US2001/020815 patent/WO2002002817A2/en active Application Filing
- 2001-06-29 AU AU2001271669A patent/AU2001271669A1/en not_active Abandoned
-
2002
- 2002-09-12 US US10/242,663 patent/US20030064402A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US6451588B1 (en) | 2002-09-17 |
WO2002002817A2 (en) | 2002-01-10 |
WO2002002817A3 (en) | 2003-03-27 |
US20030064402A1 (en) | 2003-04-03 |
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