AU2001264173A1 - Process for the isolation of lovastatin - Google Patents
Process for the isolation of lovastatinInfo
- Publication number
- AU2001264173A1 AU2001264173A1 AU2001264173A AU6417301A AU2001264173A1 AU 2001264173 A1 AU2001264173 A1 AU 2001264173A1 AU 2001264173 A AU2001264173 A AU 2001264173A AU 6417301 A AU6417301 A AU 6417301A AU 2001264173 A1 AU2001264173 A1 AU 2001264173A1
- Authority
- AU
- Australia
- Prior art keywords
- lovastatin
- isolation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN630/DEL/2000 | 2000-06-30 | ||
IN630DE2000 IN192861B (de) | 2000-06-30 | 2000-06-30 | |
PCT/IB2001/001087 WO2002000615A2 (en) | 2000-06-30 | 2001-06-20 | Process for the isolation of lovastatin |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001264173A1 true AU2001264173A1 (en) | 2002-01-08 |
Family
ID=11097066
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001264173A Abandoned AU2001264173A1 (en) | 2000-06-30 | 2001-06-20 | Process for the isolation of lovastatin |
Country Status (10)
Country | Link |
---|---|
US (1) | US7052886B2 (de) |
EP (1) | EP1299340A4 (de) |
AU (1) | AU2001264173A1 (de) |
BR (1) | BR0112024A (de) |
CA (1) | CA2412566A1 (de) |
HU (1) | HUP0301423A2 (de) |
IN (1) | IN192861B (de) |
PL (1) | PL359560A1 (de) |
WO (1) | WO2002000615A2 (de) |
ZA (1) | ZA200300006B (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2204285B1 (es) * | 2002-05-20 | 2005-03-01 | Ercros Industrial, S.A. | Procedimiento para el aislamiento y purificacion de lovastatina. |
AU2003263579A1 (en) * | 2003-08-04 | 2005-02-15 | Biocon Limited | Lactonization process |
ES2325498T3 (es) * | 2003-10-14 | 2009-09-07 | Lupin Limited | Procedimiento de fabricacion de lovastatina. |
EP1732912B1 (de) | 2004-03-30 | 2008-11-12 | Lupin Ltd. | Verbessertes verfahren zur herstellung von 4-hydroxypyran-2-onderivaten |
CN100451644C (zh) * | 2005-12-19 | 2009-01-14 | 北京维信学知科技发展有限公司 | 一种血脂康胶囊的质量检测方法 |
EP2288378A4 (de) * | 2008-04-16 | 2011-12-14 | Univ Utah Res Found | Pharmakologisches targeting von gefässfehlbildungen |
IN2009MU00380A (de) * | 2009-02-18 | 2010-04-02 | ||
CN102344426A (zh) * | 2010-07-30 | 2012-02-08 | 北大方正集团有限公司 | 一种提取并纯化洛伐他汀的方法 |
CN102993145B (zh) * | 2011-09-19 | 2015-06-03 | 北大方正集团有限公司 | 一种提取纯化洛伐他汀的方法 |
CN103172602B (zh) * | 2011-12-22 | 2015-04-29 | 北大方正集团有限公司 | 一种纯化洛伐他汀的方法 |
CN103172603B (zh) * | 2011-12-22 | 2014-12-17 | 北大方正集团有限公司 | 一种高选择性酯化处理洛伐他汀酸的洛伐他汀提取方法 |
CN102875505B (zh) * | 2012-08-02 | 2015-08-05 | 丽珠集团新北江制药股份有限公司 | 一种美伐他汀的提取精制工艺 |
CN106518824B (zh) * | 2016-09-30 | 2019-06-04 | 丽珠集团(宁夏)制药有限公司 | 一种洛伐他汀的提取工艺 |
CN106496174B (zh) * | 2016-09-30 | 2019-06-04 | 丽珠集团(宁夏)制药有限公司 | 一种洛伐他汀的提取精制工艺 |
CN115947708A (zh) * | 2022-12-20 | 2023-04-11 | 浙江天草生物科技股份有限公司 | 一种从红曲中分离高纯度酸式洛伐他汀的方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5925599B2 (ja) | 1979-02-20 | 1984-06-19 | 三共株式会社 | 新生理活性物質モナコリンkおよびその製造法 |
US4319039A (en) | 1979-06-15 | 1982-03-09 | Merck & Co., Inc. | Preparation of ammonium salt of hypocholesteremic fermentation product |
US4231938A (en) | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
US4282155A (en) | 1980-02-04 | 1981-08-04 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
US4432996A (en) * | 1980-11-17 | 1984-02-21 | Merck & Co., Inc. | Hypocholesterolemic fermentation products and process of preparation |
HU208997B (en) * | 1992-06-17 | 1994-02-28 | Gyogyszerkutato Intezet | Microbiological method for producing mevinoline |
SI9300303A (en) * | 1993-06-08 | 1994-12-31 | Krka Tovarna Zdravil | Process for isolation of hypolipemic effective substance |
CA2243592C (en) | 1995-12-06 | 2001-12-25 | Antibiotic Co. | Method of production of lovastatin |
US5763646A (en) | 1997-03-13 | 1998-06-09 | Ranbaxy Laboratories, Ltd. | Process for manufacturing simvastatin from lovastatin or mevinolinic acid |
SI9800046A (sl) * | 1998-02-18 | 1999-08-31 | LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. | Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze visoke čistosti |
AU5705000A (en) | 1999-06-29 | 2001-01-31 | Kaneka Corporation | Process for selective lactonization |
US7194013B2 (en) * | 2001-07-02 | 2007-03-20 | Nichia Corporation | GaN semiconductor laser device, and optical disk information system using the laser device |
-
2000
- 2000-06-30 IN IN630DE2000 patent/IN192861B/en unknown
-
2001
- 2001-06-20 CA CA002412566A patent/CA2412566A1/en not_active Abandoned
- 2001-06-20 AU AU2001264173A patent/AU2001264173A1/en not_active Abandoned
- 2001-06-20 US US10/311,944 patent/US7052886B2/en not_active Expired - Fee Related
- 2001-06-20 HU HU0301423A patent/HUP0301423A2/hu unknown
- 2001-06-20 PL PL01359560A patent/PL359560A1/xx not_active Application Discontinuation
- 2001-06-20 WO PCT/IB2001/001087 patent/WO2002000615A2/en not_active Application Discontinuation
- 2001-06-20 EP EP01938499A patent/EP1299340A4/de not_active Withdrawn
- 2001-06-20 BR BR0112024-7A patent/BR0112024A/pt not_active Application Discontinuation
-
2003
- 2003-01-02 ZA ZA200300006A patent/ZA200300006B/en unknown
Also Published As
Publication number | Publication date |
---|---|
IN192861B (de) | 2004-05-22 |
HUP0301423A2 (hu) | 2003-08-28 |
PL359560A1 (en) | 2004-08-23 |
WO2002000615A3 (en) | 2002-05-30 |
EP1299340A2 (de) | 2003-04-09 |
WO2002000615A2 (en) | 2002-01-03 |
US7052886B2 (en) | 2006-05-30 |
CA2412566A1 (en) | 2002-01-03 |
BR0112024A (pt) | 2003-09-09 |
US20030215932A1 (en) | 2003-11-20 |
ZA200300006B (en) | 2003-10-27 |
EP1299340A4 (de) | 2004-06-30 |
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