AU2001251587A1 - Bifunctional inhibitors of malarial proteases and uses thereof - Google Patents

Bifunctional inhibitors of malarial proteases and uses thereof

Info

Publication number
AU2001251587A1
AU2001251587A1 AU2001251587A AU5158701A AU2001251587A1 AU 2001251587 A1 AU2001251587 A1 AU 2001251587A1 AU 2001251587 A AU2001251587 A AU 2001251587A AU 5158701 A AU5158701 A AU 5158701A AU 2001251587 A1 AU2001251587 A1 AU 2001251587A1
Authority
AU
Australia
Prior art keywords
malarial
proteases
bifunctional inhibitors
bifunctional
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001251587A
Inventor
Jens W Eckstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enanta Pharmaceuticals Inc
Original Assignee
Enanta Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enanta Pharmaceuticals Inc filed Critical Enanta Pharmaceuticals Inc
Publication of AU2001251587A1 publication Critical patent/AU2001251587A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2001251587A 2000-04-21 2001-04-12 Bifunctional inhibitors of malarial proteases and uses thereof Abandoned AU2001251587A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19902300P 2000-04-21 2000-04-21
US60199023 2000-04-21
PCT/US2001/012000 WO2001083433A1 (en) 2000-04-21 2001-04-12 Bifunctional inhibitors of malarial proteases and uses thereof

Publications (1)

Publication Number Publication Date
AU2001251587A1 true AU2001251587A1 (en) 2001-11-12

Family

ID=22735884

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001251587A Abandoned AU2001251587A1 (en) 2000-04-21 2001-04-12 Bifunctional inhibitors of malarial proteases and uses thereof

Country Status (3)

Country Link
EP (1) EP1274679A1 (en)
AU (1) AU2001251587A1 (en)
WO (1) WO2001083433A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002078714A1 (en) * 2001-03-30 2002-10-10 Jomaa Pharmaka Gmbh Formulations which are resistant to gastric juice and are used to apply anti-infective compounds inhibiting the 2-c-methylerythrose-4 metabolic pathway, and the salts and esters of the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL112759A0 (en) * 1994-02-25 1995-05-26 Khepri Pharmaceuticals Inc Novel cysteine protease inhibitors

Also Published As

Publication number Publication date
EP1274679A1 (en) 2003-01-15
WO2001083433A1 (en) 2001-11-08

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