AU2002218084A1 - Inhibitors of thromboxane formation and action - Google Patents

Inhibitors of thromboxane formation and action

Info

Publication number
AU2002218084A1
AU2002218084A1 AU2002218084A AU1808402A AU2002218084A1 AU 2002218084 A1 AU2002218084 A1 AU 2002218084A1 AU 2002218084 A AU2002218084 A AU 2002218084A AU 1808402 A AU1808402 A AU 1808402A AU 2002218084 A1 AU2002218084 A1 AU 2002218084A1
Authority
AU
Australia
Prior art keywords
inhibitors
action
thromboxane formation
thromboxane
formation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2002218084A
Inventor
Cecil R. Pace-Asciak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hospital for Sick Children HSC
Original Assignee
Hospital for Sick Children HSC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hospital for Sick Children HSC filed Critical Hospital for Sick Children HSC
Publication of AU2002218084A1 publication Critical patent/AU2002218084A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/559—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing hetero atoms other than oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2002218084A 2000-11-09 2001-11-09 Inhibitors of thromboxane formation and action Abandoned AU2002218084A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US24674400P 2000-11-09 2000-11-09
US60/246,744 2000-11-09
US29975201P 2001-06-22 2001-06-22
US60/299,752 2001-06-22
PCT/CA2001/001607 WO2002038157A2 (en) 2000-11-09 2001-11-09 Inhibitors of thromboxane formation and action

Publications (1)

Publication Number Publication Date
AU2002218084A1 true AU2002218084A1 (en) 2002-05-21

Family

ID=26938185

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002218084A Abandoned AU2002218084A1 (en) 2000-11-09 2001-11-09 Inhibitors of thromboxane formation and action

Country Status (4)

Country Link
US (1) US8071654B2 (en)
AU (1) AU2002218084A1 (en)
CA (1) CA2427774C (en)
WO (1) WO2002038157A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1509229B1 (en) * 2002-05-28 2009-09-23 Pace- Asciak, Cecil R. Compositions comprising hepoxilin analogs and their use in the treatment of cancer
EP1604668A1 (en) * 2004-06-03 2005-12-14 Institut National De La Sante Et De La Recherche Medicale (Inserm) Hepoxilins and modulators of ichthyin for treating skin disorders
WO2006106438A2 (en) * 2005-01-11 2006-10-12 Evolva Sa Modulators of ppar activity
RU2449999C2 (en) * 2006-01-18 2012-05-10 Эвольва Са Ppar modulators
CA2643972C (en) 2006-04-19 2012-01-03 Peter Demin Hepoxilin analog enantiomers
WO2008089463A2 (en) * 2007-01-18 2008-07-24 Evolva Sa Substituted 1,3-dioxanes and their uses
CN114560753B (en) * 2020-11-27 2024-04-26 深圳千越生物科技有限公司 Process for preparing hydroxy epoxy analogues

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0691963B1 (en) * 1993-03-29 1998-07-15 HSC Research and Development Limited Partnership Hepoxilin analogs useful as anti-inflammatory agents
US5783564A (en) * 1993-12-24 1998-07-21 Mitsubishi Chemical Corporation Sialic acid derivatives
US5789441A (en) 1996-02-15 1998-08-04 Virocell Inc. Leukotriene B4 as an antiviral and anti-neoplastic agent
US6093742A (en) * 1997-06-27 2000-07-25 Vertex Pharmaceuticals, Inc. Inhibitors of p38
US6391305B1 (en) * 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
WO1999059578A1 (en) 1998-05-19 1999-11-25 Research Development Foundation Triterpene compositions and methods for use thereof
KR100325581B1 (en) 1998-08-07 2002-08-24 오우택 Analgesic compositions containing substances that result from lipoxygenase metabolism of arachidonic acid
CA2393904C (en) * 1999-08-04 2012-10-16 Hsc Research And Development Limited Partnership Hepoxilin analogs
US6673785B1 (en) * 1999-08-04 2004-01-06 Cecil R. Pace-Asciak Use of hepoxilins or hepoxilin analogs as antidiabetics, antiinflammatory agents
EP1509229B1 (en) 2002-05-28 2009-09-23 Pace- Asciak, Cecil R. Compositions comprising hepoxilin analogs and their use in the treatment of cancer

Also Published As

Publication number Publication date
US20040132705A1 (en) 2004-07-08
WO2002038157A2 (en) 2002-05-16
CA2427774A1 (en) 2002-05-16
WO2002038157A3 (en) 2003-02-27
US8071654B2 (en) 2011-12-06
CA2427774C (en) 2013-01-15

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