AU2001239884B2 - Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins and screening methods for modulators - Google Patents
Materials and methods involving hybrid vascular endothelial growth factor DNAs and proteins and screening methods for modulators Download PDFInfo
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0692—Stem cells; Progenitor cells; Precursor cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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| JP4981229B2 (ja) * | 2000-02-25 | 2012-07-18 | ルードヴィッヒ インスティテュート フォー キャンサー リサーチ | ハイブリッド血管内皮成長因子ＤＮＡｓおよびタンパク質に関与する物質および方法 |
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| EP1289565B1 (en) | 2000-06-02 | 2015-04-22 | Bracco Suisse SA | Compounds for targeting endothelial cells |
| WO2002014367A1 (fr) * | 2000-08-10 | 2002-02-21 | Center For Advanced Science And Technology Incubation,Ltd. | Facteur de croissance chimere de cellules endotheliales vasculaires de type humain |
| CA2435503C (en) * | 2001-01-19 | 2011-02-22 | Ludwig Institute For Cancer Research | Flt4(vegfr-3) as a target for tumor imaging and anti-tumor therapy |
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| US7261876B2 (en) | 2002-03-01 | 2007-08-28 | Bracco International Bv | Multivalent constructs for therapeutic and diagnostic applications |
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| US8623822B2 (en) | 2002-03-01 | 2014-01-07 | Bracco Suisse Sa | KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy |
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| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
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| WO2005016963A2 (en) * | 2003-06-12 | 2005-02-24 | Ludwig Institute For Cancer Research | Heparin binding veger-3 ligands |
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| EP1732947B1 (en) | 2004-03-05 | 2011-04-27 | Vegenics Pty Ltd | Growth factor binding constructs materials and methods |
| US7476654B2 (en) * | 2004-03-08 | 2009-01-13 | Ludwig Institute For Cancer Research | Method for modulating, regulating and/or stabilizing angiogenesis |
| AU2005269527B2 (en) | 2004-07-26 | 2011-12-01 | Pfenex Inc. | Process for improved protein expression by strain engineering |
| US7553496B2 (en) * | 2004-12-21 | 2009-06-30 | University Of Kentucky Research Foundation | VEGF-A as an inhibitor of angiogenesis and methods of using same |
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| EP1919944B1 (en) | 2005-08-15 | 2011-03-23 | Vegenics Pty Ltd | Modified vegf and pdgf with improved angiogenic properties |
| JP2009519011A (ja) * | 2005-12-01 | 2009-05-14 | ドマンティス リミテッド | インターロイキン１受容体１型に結合する非競合ドメイン抗体フォーマット |
| WO2007089780A2 (en) * | 2006-01-30 | 2007-08-09 | Licentia, Ltd. | Bmx/etk tyrosine kinase gene therapy materials and methods |
| CN1903880B (zh) * | 2006-08-02 | 2010-05-12 | 中国人民解放军军事医学科学院基础医学研究所 | 抗肿瘤血管内皮生长因子vegf-e抗原及其编码基因与应用 |
| WO2008096268A2 (en) * | 2007-02-07 | 2008-08-14 | Vegenics Limited | Autologous lymph node transfer in combination with vegf-c or vegf-d growth factor therapy to treat secondary lymphedema and to improve reconstructive surgery |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| EP2142651B1 (en) | 2007-04-27 | 2013-05-22 | Pfenex Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
| EA200901301A1 (ru) | 2007-06-06 | 2010-06-30 | Домантис Лимитед | Полипептиды, вариабельные домены антител и антагонисты |
| WO2010065995A1 (en) * | 2008-12-08 | 2010-06-17 | Vegenics Limited | Isolated vegf-c and vegf-d peptides and uses thereof |
| WO2011154308A1 (en) | 2010-06-08 | 2011-12-15 | Proyecto De Biomedicina Cima, S.L. | New compositions and cell therapy methods for the treatment of cirrhosis |
| WO2012088563A1 (en) * | 2010-11-24 | 2012-07-05 | Vegenics Pty Limited | Vegfr-2-specific forms of vegf-d and vegf-c and uses thereof |
| WO2014081772A1 (en) * | 2012-11-20 | 2014-05-30 | Albert Einstein College Of Medicine Of Yeshiva University | Regeneration of coronary artery by coronary endothelial specific progenitor cells |
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| WO2016115506A1 (en) * | 2015-01-16 | 2016-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Hybrid chimera polypeptides as dual inhibitors of vascular endothelial growth factor receptor and platelet-derived growth factor receptor |
| US11628190B2 (en) * | 2015-08-28 | 2023-04-18 | University Of South Florida | Plasma derived from human umbilical cord blood for the treatment of neurodegenerative disorders |
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Also Published As
| Publication number | Publication date |
|---|---|
| AU3988401A (en) | 2001-09-03 |
| US7902149B2 (en) | 2011-03-08 |
| ATE377081T1 (de) | 2007-11-15 |
| WO2001062942A2 (en) | 2001-08-30 |
| US7309604B2 (en) | 2007-12-18 |
| US20050267024A1 (en) | 2005-12-01 |
| US6965010B2 (en) | 2005-11-15 |
| EP1259626A2 (en) | 2002-11-27 |
| US8278098B2 (en) | 2012-10-02 |
| US20020151680A1 (en) | 2002-10-17 |
| US20110207664A1 (en) | 2011-08-25 |
| DE60131146T2 (de) | 2008-03-06 |
| US7566566B2 (en) | 2009-07-28 |
| US20090318352A1 (en) | 2009-12-24 |
| CA2400948A1 (en) | 2001-08-30 |
| WO2001062942A3 (en) | 2002-03-21 |
| JP2004507208A (ja) | 2004-03-11 |
| JP4981229B2 (ja) | 2012-07-18 |
| EP1259626B1 (en) | 2007-10-31 |
| US20080058263A1 (en) | 2008-03-06 |
| DE60131146D1 (de) | 2007-12-13 |
| AU2001239884C1 (en) | 2001-09-03 |
| AU2006235995A1 (en) | 2006-12-07 |
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