AU2001238690A1 - 3-substituted piperidines comprising urea functionality, and methods of use thereof - Google Patents
3-substituted piperidines comprising urea functionality, and methods of use thereofInfo
- Publication number
- AU2001238690A1 AU2001238690A1 AU2001238690A AU3869001A AU2001238690A1 AU 2001238690 A1 AU2001238690 A1 AU 2001238690A1 AU 2001238690 A AU2001238690 A AU 2001238690A AU 3869001 A AU3869001 A AU 3869001A AU 2001238690 A1 AU2001238690 A1 AU 2001238690A1
- Authority
- AU
- Australia
- Prior art keywords
- methods
- substituted piperidines
- urea functionality
- urea
- functionality
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Engineering & Computer Science (AREA)
- Addiction (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18934900P | 2000-03-14 | 2000-03-14 | |
US60189349 | 2000-03-14 | ||
PCT/US2001/006050 WO2001068604A2 (fr) | 2000-03-14 | 2001-02-23 | Piperidines 3-substituees comprenant un groupement uree et procedes d'utilisation de ces dernieres |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2001238690A1 true AU2001238690A1 (en) | 2001-09-24 |
Family
ID=22696932
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2001238690A Abandoned AU2001238690A1 (en) | 2000-03-14 | 2001-02-23 | 3-substituted piperidines comprising urea functionality, and methods of use thereof |
Country Status (3)
Country | Link |
---|---|
US (2) | US6476050B2 (fr) |
AU (1) | AU2001238690A1 (fr) |
WO (1) | WO2001068604A2 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2422055A1 (fr) | 2000-09-11 | 2002-03-21 | Sepracor, Inc. | Ligands pour les recepteurs de monoamine et transporteurs, et procedes d'utilisation de ces derniers |
US7294637B2 (en) | 2000-09-11 | 2007-11-13 | Sepracor, Inc. | Method of treating addiction or dependence using a ligand for a monamine receptor or transporter |
EP1918279A3 (fr) * | 2001-04-18 | 2008-07-16 | Euro-Celtique S.A. | Dérivés de la 1-(4-pipéridinyl)-1,3-dihydro-2h-benzoxazole-2-one et composés similaires en tant que analogues de la nociceptine et ligandes du récepteur resemblant le récepteur opioid pour le traitement de la douleur |
AR034897A1 (es) | 2001-08-07 | 2004-03-24 | Hoffmann La Roche | Derivados n-monoacilados de o-fenilendiaminas, sus analogos heterociclicos de seis miembros y su uso como agentes farmaceuticos |
US6919356B2 (en) | 2002-09-26 | 2005-07-19 | Bristol Myers Squibb Company | N-substituted heterocyclic amines as modulators of chemokine receptor activity |
GB0230195D0 (en) * | 2002-12-24 | 2003-02-05 | Biofocus Plc | Compound Libraries |
US7153858B2 (en) * | 2003-01-31 | 2006-12-26 | Epix Delaware, Inc. | Arylpiperazinyl compounds |
US20050119266A1 (en) * | 2003-10-01 | 2005-06-02 | Yan Shi | Pyrrolidine and piperidine derivatives as factor Xa inhibitors |
US7775002B2 (en) * | 2006-11-10 | 2010-08-17 | John Puchniak | Portable hurricane and security window barrier |
US8338142B2 (en) | 2007-02-19 | 2012-12-25 | Kaneka Corporation | Method for producing optically active 3-aminopiperidine or salt thereof |
EP1997805A1 (fr) * | 2007-06-01 | 2008-12-03 | Commissariat à l'Energie Atomique | Compositions à activité antiparasite, applications associées au traitement des maladies infectieuses causées par des apicomplexans |
US8138168B1 (en) * | 2007-09-26 | 2012-03-20 | Takeda Pharmaceutical Company Limited | Renin inhibitors |
EP2958894B8 (fr) * | 2013-02-20 | 2020-02-26 | Reuter Chemische Apparatenbau e.K. | Procédé de préparation d'une 3-aminopipéridine enrichie en énantiomères |
CN104292213A (zh) * | 2014-09-08 | 2015-01-21 | 湖南华腾制药有限公司 | 一种嘧啶衍生物的制备方法 |
WO2016116788A1 (fr) | 2015-01-24 | 2016-07-28 | Wockhardt Limited | Composés bicycliques contenant de l'azote et leur utilisation dans le traitement d'infections bactériennes |
CA3087886A1 (fr) | 2018-01-19 | 2019-07-25 | Idorsia Pharmaceuticals Ltd | Modulateurs du recepteur c5a |
AU2021267373A1 (en) | 2020-05-06 | 2022-12-08 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors |
WO2023086319A1 (fr) | 2021-11-09 | 2023-05-19 | Ajax Therapeutics, Inc. | 6-hetero-aryloxy-benzimidazoles et azabenzimidazoles en tant qu'inhibiteurs de jak2 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH460028A (de) | 1965-01-22 | 1968-07-31 | Wander Ag Dr A | Verfahren zur Herstellung von Benzimidazolonderivaten |
JPS5152176A (fr) | 1974-10-12 | 1976-05-08 | Yoshitomi Pharmaceutical | |
JPS539770A (en) * | 1976-07-13 | 1978-01-28 | Yoshitomi Pharmaceut Ind Ltd | Novel 3-substituted pyrrolidine derivatives |
US4181802A (en) * | 1978-05-11 | 1980-01-01 | Janssen Pharmaceutica N.V. | 1-(Heterocyclylalkyl)-1,3-dihydro-2-H-benzimidazole-2-ones |
JPS58180481A (ja) | 1982-04-15 | 1983-10-21 | Kyowa Hakko Kogyo Co Ltd | 新規なピペリジン誘導体 |
US4694004A (en) | 1984-07-09 | 1987-09-15 | Fujisawa Pharmaceutical Co., Ltd. | Semicarbazide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same |
FR2592879B1 (fr) * | 1986-01-13 | 1988-04-29 | Roussel Uclaf | Nouveaux derives de la decahydroquinoleine, leur procede de preparation, les intermediaires de preparation, leur application a titre de medicaments et les compositions les renfermant |
US4791112A (en) | 1987-02-02 | 1988-12-13 | The Boc Group, Inc. | N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds |
DK247789A (da) | 1988-05-23 | 1989-11-24 | Glaxo Group Ltd | Piperazinderivater |
US5019583A (en) | 1989-02-15 | 1991-05-28 | Glaxo Inc. | N-phenyl-N-(4-piperidinyl)amides useful as analgesics |
JP3087763B2 (ja) * | 1990-11-30 | 2000-09-11 | 三井化学株式会社 | 新規な複素環式化合物およびそれを含有する医薬組成物 |
US5270328A (en) * | 1991-03-29 | 1993-12-14 | Eli Lilly And Company | Peripherally selective piperidine opioid antagonists |
US5159081A (en) * | 1991-03-29 | 1992-10-27 | Eli Lilly And Company | Intermediates of peripherally selective n-carbonyl-3,4,4-trisubstituted piperidine opioid antagonists |
US5721250A (en) * | 1993-12-23 | 1998-02-24 | Merck & Co. Inc. | Di-and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
DE4440437C1 (de) * | 1994-11-11 | 1996-02-08 | Ejot Verbindungstech Gmbh & Co | Selbstbohrende und gewindeformende Schraube mit Fließformabschnitt |
CA2238081A1 (fr) | 1995-11-22 | 1997-05-29 | S. Jane Desolms | Inhibiteurs de la farnesyl-proteine transferase |
DE69729583T2 (de) * | 1996-04-17 | 2005-06-09 | Bristol-Myers Squibb Pharma Co. | N-(amidinophenyl)-n'-(subst.)-3h-2,4-benzodiazepin-3-on derivative als faktor xa inhibitoren |
US5840500A (en) * | 1996-07-11 | 1998-11-24 | Trega Biosciences, Inc. | Quinoline derivatives and quinoline combinatorial libraries |
US5786448A (en) * | 1996-11-07 | 1998-07-28 | Trega Biosciences, Inc. | Combinatorial libraries of cyclic urea and cyclic thiourea derivatives and compounds therein |
US6262269B1 (en) * | 1997-02-04 | 2001-07-17 | Trega Biosciences, Inc. | 4-Substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries |
US5925527A (en) * | 1997-02-04 | 1999-07-20 | Trega Biosciences, Inc. | Tricyclic Tetrahydroquinoline derivatives and tricyclic tetrahydroquinoline combinatorial libraries |
FR2784377B3 (fr) | 1998-10-09 | 2000-11-17 | Sanofi Sa | Nouveaux composes derives d'ureidopiperidine, antagonistes selectifs des recepteurs nk3 humains, procede pour leur obtention et compositions pharmaceutiques les contenant |
US6133291A (en) | 1998-10-16 | 2000-10-17 | Schering Corporation | N-(imidazolylalkyl)substituted cyclic amines as histamine-H3 agonists or antagonists |
WO2000071518A2 (fr) | 1999-05-25 | 2000-11-30 | Sepracor, Inc. | Composes heterocycliques analgesiques et procedes d'utilisation de ces derniers |
CA2377369A1 (fr) | 1999-06-04 | 2000-12-14 | Merck & Co., Inc. | Piperidines substituees en tant qu'agonistes du recepteur de melanocortine-4 |
AU6525300A (en) | 1999-08-13 | 2001-03-13 | Sepracor, Inc. | Spirocyclic ligands for sigma receptors, and libraries and methods of use thereof |
-
2001
- 2001-02-23 WO PCT/US2001/006050 patent/WO2001068604A2/fr active Application Filing
- 2001-02-23 US US09/792,866 patent/US6476050B2/en not_active Expired - Lifetime
- 2001-02-23 AU AU2001238690A patent/AU2001238690A1/en not_active Abandoned
-
2002
- 2002-11-05 US US10/289,121 patent/US6946477B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO2001068604A2 (fr) | 2001-09-20 |
US6476050B2 (en) | 2002-11-05 |
WO2001068604A3 (fr) | 2002-03-28 |
US20010056090A1 (en) | 2001-12-27 |
US6946477B2 (en) | 2005-09-20 |
US20030114436A1 (en) | 2003-06-19 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2001285409A1 (en) | Memory devices and methods for use therewith | |
HUP0300527A3 (en) | Pyrrolopyrimidinone derivatives, process of preparation and use | |
AU2001238690A1 (en) | 3-substituted piperidines comprising urea functionality, and methods of use thereof | |
AU2002360561A1 (en) | 4-substituted piperidines, and methods of use thereof | |
AU2001237996A1 (en) | Thermally and chemically treating cells | |
AU2002225954A1 (en) | Dipeptidylpeptidases and methods of use | |
AU2001280599A1 (en) | Compounds and methods | |
AU2002359126A1 (en) | Benzodiazepine derivatives, preparation thereof and use thereof | |
AU2001253418A1 (en) | Compounds and methods | |
AU2002361861A1 (en) | SELECTIVE 11Beta-HSD INHIBITORS AND METHODS FOR USE THEREOF | |
MXPA01011475A (es) | Polimero superabsorbente acuoso y metodos para uso. | |
AU2002359123A1 (en) | Benzodiazepine derivatives, preparation thereof and use thereof | |
AU2001288972A1 (en) | Antipsychotic sulfonamide-heterocycles, and methods of use thereof | |
AU6635800A (en) | Pyridomorphinans, thienomoprhinans and use thereof | |
AU2001243394A1 (en) | Compounds and methods | |
AU2001267645A1 (en) | Cyclic urea compounds and preparation thereof | |
PL352432A1 (en) | Neurothrophic pyrolydines and piperidines, their affinite composition and methods of using them | |
AU7332800A (en) | Card construction, methods of making and using | |
AU2002251140A1 (en) | Chemical derivatives and their use as anti-telomerase agent | |
AU2001283299A1 (en) | Basecalling system and protocol | |
AUPQ872300A0 (en) | Compounds and methods | |
AU3883800A (en) | Hob-bp2h compositions, methods and uses thereof | |
AU2001278951A1 (en) | Compounds and methods | |
AU2001261496A1 (en) | Luxo-sigma54 interactions and methods of use | |
AU2001243601A1 (en) | Caprolactam derivatives and uses thereof |