AU2001234883A1 - Method of analyzing single nucleotide polymorphisms using melting curve and restriction endonuclease digestion - Google Patents

Method of analyzing single nucleotide polymorphisms using melting curve and restriction endonuclease digestion

Info

Publication number
AU2001234883A1
AU2001234883A1 AU2001234883A AU3488301A AU2001234883A1 AU 2001234883 A1 AU2001234883 A1 AU 2001234883A1 AU 2001234883 A AU2001234883 A AU 2001234883A AU 3488301 A AU3488301 A AU 3488301A AU 2001234883 A1 AU2001234883 A1 AU 2001234883A1
Authority
AU
Australia
Prior art keywords
single nucleotide
restriction endonuclease
nucleotide polymorphisms
melting curve
endonuclease digestion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001234883A
Inventor
Joshua M. Akey
Mark D. Shriver
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penn State Research Foundation
Original Assignee
Penn State Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penn State Research Foundation filed Critical Penn State Research Foundation
Publication of AU2001234883A1 publication Critical patent/AU2001234883A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
AU2001234883A 2000-02-10 2001-02-07 Method of analyzing single nucleotide polymorphisms using melting curve and restriction endonuclease digestion Abandoned AU2001234883A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US18161800P 2000-02-10 2000-02-10
US60181618 2000-02-10
US19685500P 2000-04-12 2000-04-12
US60196855 2000-04-12
PCT/US2001/003893 WO2001059144A1 (en) 2000-02-10 2001-02-07 Method of analyzing single nucleotide polymorphisms using melting curve and restriction endonuclease digestion

Publications (1)

Publication Number Publication Date
AU2001234883A1 true AU2001234883A1 (en) 2001-08-20

Family

ID=26877345

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001234883A Abandoned AU2001234883A1 (en) 2000-02-10 2001-02-07 Method of analyzing single nucleotide polymorphisms using melting curve and restriction endonuclease digestion

Country Status (3)

Country Link
US (1) US6506568B2 (en)
AU (1) AU2001234883A1 (en)
WO (1) WO2001059144A1 (en)

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US6979541B1 (en) * 2001-07-26 2005-12-27 University Of Utah Research Foundation Methods for identifying chromosomal aneuploidy
WO2003091408A2 (en) * 2002-04-26 2003-11-06 University Of Utah Research Foundation Characterization of single stranded nucleic acids by melting analysis using a double strand specific nucleic acid dye
EP1510576A4 (en) * 2002-05-21 2007-08-22 G & G Science Co Ltd Methods of identifying nucleic acids
WO2004003220A2 (en) * 2002-06-28 2004-01-08 Orchid Biosciences, Inc Methods and composition for analyzing compromised samples using snps
KR100477766B1 (en) * 2002-09-26 2005-03-21 (주)진매트릭스 Primers and method for detecting base mutation
EP2772552B1 (en) 2002-10-23 2018-10-10 University of Utah Research Foundation Amplicon melting analysis with saturation dyes
CA2429101A1 (en) * 2002-10-24 2004-04-24 Ben Gao Method and equipment to monitor nucleic acid hybridization on a dna chip using four-dimensional parameters
ATE488604T1 (en) * 2003-05-20 2010-12-15 Investigen Inc POLYNUCLEOTIDE DETECTION SYSTEM
DE10324912A1 (en) * 2003-05-30 2005-01-05 Siemens Ag Method for the detection of DNA point mutations (SNP analysis) and associated arrangement
EP1687609B1 (en) * 2003-10-28 2014-12-10 Epoch Biosciences, Inc. Fluorescent probes for dna detection by hybridization with improved sensitivity and low background
US7387887B2 (en) * 2004-04-20 2008-06-17 University Of Utah Research Foundation Nucleic acid melting analysis with saturation dyes
US9657347B2 (en) 2004-04-20 2017-05-23 University of Utah Research Foundation and BioFire Defense, LLC Nucleic acid melting analysis with saturation dyes
US20050255483A1 (en) * 2004-05-14 2005-11-17 Stratagene California System and method for smoothing melting curve data
KR100808312B1 (en) * 2004-07-26 2008-02-27 홍경만 Method for measuring the chromosome, gene or nucleotide sequence copy numbers using co-amplification of artificial SNP sequences
US7456281B2 (en) * 2005-04-20 2008-11-25 Idaho Technology, Inc. Nucleic acid melting analysis with saturation dyes
GB0512116D0 (en) * 2005-06-14 2005-07-20 Matforsk Norwegian Food Res In Classification method
US20070198653A1 (en) * 2005-12-30 2007-08-23 Kurt Jarnagin Systems and methods for remote computer-based analysis of user-provided chemogenomic data
US8021839B2 (en) * 2006-02-24 2011-09-20 Investigen, Inc. Methods and compositions for detecting polynucleotides
US7771947B2 (en) * 2007-02-23 2010-08-10 Investigen, Inc. Methods and compositions for rapid light-activated isolation and detection of analytes
EP3091088B1 (en) * 2007-03-28 2019-02-06 Signal Diagnostics System and method for high resolution analysis of nucleic acids to detect sequence variations
US8364415B2 (en) * 2007-12-26 2013-01-29 Arkray, Inc. Melting curve analyzing method and melting curve analyzing device
US10669574B2 (en) 2008-11-18 2020-06-02 XCR Diagnostics, Inc. DNA amplification technology
EP2530166B1 (en) * 2011-05-31 2014-07-16 ARKRAY, Inc. Method for detecting a plurality of nucleotide polymorphisms at a single wavelength using a plurality of oligonucleotides modified with fluorescent dye having the same or close detection wavelength
AU2013202808B2 (en) 2012-07-31 2014-11-13 Gen-Probe Incorporated System and method for performing multiplex thermal melt analysis
IN2015DN01609A (en) * 2012-08-03 2015-07-03 California Inst Of Techn
AU2014331828B2 (en) 2013-10-09 2020-05-14 Fluoresentric, Inc. Multiplex probes
EP3058098A4 (en) * 2013-10-18 2017-03-22 Institut de Cardiologie de Montréal Genotyping tests and methods for evaluating plasma creatine kinase levels
CN103589797A (en) * 2013-11-12 2014-02-19 中国农业科学院蔬菜花卉研究所 SNP (single nucleotide polymorphism) genotyping method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110709A (en) * 1994-03-18 2000-08-29 The General Hospital Corporation Cleaved amplified modified polymorphic sequence detection methods
AUPO882497A0 (en) 1997-08-29 1997-09-18 Grains Research & Development Corporation A method of genotyping
GB9821989D0 (en) 1998-10-08 1998-12-02 Hybaid Ltd Detection of nucleic acid polymorphism
GB0020633D0 (en) 2000-08-22 2000-10-11 Moulton Development Ltd Recumbent bicycle

Also Published As

Publication number Publication date
US6506568B2 (en) 2003-01-14
US20020098484A1 (en) 2002-07-25
WO2001059144A1 (en) 2001-08-16

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