AU2000232427A1 - HLA binding peptides and their uses - Google Patents
HLA binding peptides and their usesInfo
- Publication number
- AU2000232427A1 AU2000232427A1 AU2000232427A AU3242700A AU2000232427A1 AU 2000232427 A1 AU2000232427 A1 AU 2000232427A1 AU 2000232427 A AU2000232427 A AU 2000232427A AU 3242700 A AU3242700 A AU 3242700A AU 2000232427 A1 AU2000232427 A1 AU 2000232427A1
- Authority
- AU
- Australia
- Prior art keywords
- peptide
- peptides
- cells
- ctl
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 108010036972 HLA-A11 Antigen Proteins 0.000 description 1
- 108010074032 HLA-A2 Antigen Proteins 0.000 description 1
- 102000025850 HLA-A2 Antigen Human genes 0.000 description 1
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- WSDOHRLQDGAOGU-BQBZGAKWSA-N His-Asn Chemical compound NC(=O)C[C@@H](C(O)=O)NC(=O)[C@@H](N)CC1=CN=CN1 WSDOHRLQDGAOGU-BQBZGAKWSA-N 0.000 description 1
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- 101000924577 Homo sapiens Adenomatous polyposis coli protein Proteins 0.000 description 1
- 101001005718 Homo sapiens Melanoma-associated antigen 2 Proteins 0.000 description 1
- 101000979735 Homo sapiens NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial Proteins 0.000 description 1
- 101000830565 Homo sapiens Tumor necrosis factor ligand superfamily member 10 Proteins 0.000 description 1
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- 108010002350 Interleukin-2 Proteins 0.000 description 1
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- 150000008575 L-amino acids Chemical class 0.000 description 1
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- NPBGTPKLVJEOBE-IUCAKERBSA-N Lys-Arg Chemical compound NCCCC[C@H](N)C(=O)N[C@H](C(O)=O)CCCNC(N)=N NPBGTPKLVJEOBE-IUCAKERBSA-N 0.000 description 1
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- KZNQNBZMBZJQJO-UHFFFAOYSA-N N-glycyl-L-proline Natural products NCC(=O)N1CCCC1C(O)=O KZNQNBZMBZJQJO-UHFFFAOYSA-N 0.000 description 1
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- IPVPGAADZXRZSH-RNXOBYDBSA-N Phe-Tyr-Trp Chemical compound [H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O IPVPGAADZXRZSH-RNXOBYDBSA-N 0.000 description 1
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- GQPQJNMVELPZNQ-GBALPHGKSA-N Thr-Ser-Trp Chemical compound C[C@H]([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)O)N)O GQPQJNMVELPZNQ-GBALPHGKSA-N 0.000 description 1
- GSCPHMSPGQSZJT-JYBASQMISA-N Trp-Ser-Thr Chemical compound C[C@H]([C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)N)O GSCPHMSPGQSZJT-JYBASQMISA-N 0.000 description 1
- TYYLDKGBCJGJGW-WMZOPIPTSA-N Trp-Tyr Chemical compound C([C@H](NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)N)C(O)=O)C1=CC=C(O)C=C1 TYYLDKGBCJGJGW-WMZOPIPTSA-N 0.000 description 1
- 102100024598 Tumor necrosis factor ligand superfamily member 10 Human genes 0.000 description 1
- BMPPMAOOKQJYIP-WMZOPIPTSA-N Tyr-Trp Chemical compound C([C@H]([NH3+])C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C([O-])=O)C1=CC=C(O)C=C1 BMPPMAOOKQJYIP-WMZOPIPTSA-N 0.000 description 1
- 102100039094 Tyrosinase Human genes 0.000 description 1
- 108060008724 Tyrosinase Proteins 0.000 description 1
- GVJUTBOZZBTBIG-AVGNSLFASA-N Val-Lys-Arg Chemical compound CC(C)[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O)N GVJUTBOZZBTBIG-AVGNSLFASA-N 0.000 description 1
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- 125000003118 aryl group Chemical group 0.000 description 1
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- 239000011230 binding agent Substances 0.000 description 1
- 108091008324 binding proteins Proteins 0.000 description 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
- 230000003833 cell viability Effects 0.000 description 1
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- 108010063718 gamma-glutamylaspartic acid Proteins 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 108010042598 glutamyl-aspartyl-glycine Proteins 0.000 description 1
- KZNQNBZMBZJQJO-YFKPBYRVSA-N glyclproline Chemical compound NCC(=O)N1CCC[C@H]1C(O)=O KZNQNBZMBZJQJO-YFKPBYRVSA-N 0.000 description 1
- 108010077515 glycylproline Proteins 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2000/004655 WO2001062776A1 (fr) | 2000-02-23 | 2000-02-23 | Peptides de liaison hla et utilisations de ces derniers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2000232427A1 true AU2000232427A1 (en) | 2001-09-03 |
Family
ID=21741082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2000232427A Abandoned AU2000232427A1 (en) | 2000-02-23 | 2000-02-23 | HLA binding peptides and their uses |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1263775A4 (fr) |
| JP (1) | JP2003524016A (fr) |
| CN (1) | CN1452634A (fr) |
| AU (1) | AU2000232427A1 (fr) |
| BR (1) | BR0017136A (fr) |
| CA (1) | CA2400215A1 (fr) |
| MX (1) | MXPA02008219A (fr) |
| WO (1) | WO2001062776A1 (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5898400A (en) * | 1999-06-29 | 2001-01-31 | Epimmune, Inc. | Hla binding peptides and their uses |
| AU2001242190A1 (en) * | 2000-03-31 | 2001-10-15 | Aventis Pasteur Limited | Immunogenic peptides derived from prostate-specific membrane antigen (psma) and uses thereof |
| US20030113919A1 (en) * | 2001-08-17 | 2003-06-19 | Aventis Pasteur, Ltd. | Immunogenic targets for melanoma |
| KR20070056042A (ko) | 2004-06-17 | 2007-05-31 | 맨카인드 코포레이션 | 에피토프 유사체 |
| US8487076B1 (en) * | 2005-01-25 | 2013-07-16 | Nec Corporation | HLA-binding peptide, and DNA fragment and recombinant vector coding for said HLA-binding peptide |
| JP5416968B2 (ja) * | 2005-06-17 | 2014-02-12 | マンカインド コーポレイション | 癌細胞及び腫瘍間質上に発現される優勢及び亜優勢エピトープに対する多価免疫応答を誘発するための方法及び組成物 |
| KR20080028938A (ko) | 2005-06-17 | 2008-04-02 | 맨카인드 코포레이션 | 에피토프 유사체 |
| CN1948333B (zh) * | 2005-10-14 | 2010-12-08 | 中国人民解放军第二军医大学 | 一种新的hPEBP4蛋白来源的HLA-A2限制性表位多肽及其应用 |
| WO2008031064A1 (fr) * | 2006-09-07 | 2008-03-13 | University Of South Florida | Peptides hyd1 en tant qu'agents anticancéreux |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| JP5792630B2 (ja) | 2009-01-28 | 2015-10-14 | エピミューン，インコーポレイティド | Ｐａｎ−ｄｒ結合ポリペプチドおよびその使用 |
| CA2793838C (fr) | 2010-03-19 | 2019-09-17 | H. Lee Moffitt Cancer Center & Research Institute, Inc. | Inhibiteurs des interactions de l'integrine pour traiter le cancer |
| US20130183376A1 (en) | 2010-09-08 | 2013-07-18 | Saitama Medical University | Hepatitis c virus liposome vaccine |
| US10011635B2 (en) | 2013-09-27 | 2018-07-03 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Cyclic peptide conjugates and methods of use |
| EP3522917A2 (fr) | 2016-10-07 | 2019-08-14 | Enterome S.A. | Variants de séquence de microbiote d'épitopes antigéniques associés à une tumeur |
| US11478538B2 (en) | 2016-10-07 | 2022-10-25 | Enterome S.A. | Immunogenic compounds for cancer therapy |
| KR102622188B1 (ko) | 2016-10-07 | 2024-01-05 | 엔터롬 에스.에이. | 암 치료를 위한 면역원성 화합물 |
| KR20190082850A (ko) | 2016-11-30 | 2019-07-10 | 어드박시스, 인크. | 반복되는 암 돌연변이를 표적화하는 면역원 조성물 및 그것의 사용 방법 |
| KR20200070405A (ko) * | 2017-11-08 | 2020-06-17 | 어드박시스, 인크. | 암 관련 단백질로부터의 면역원성 불규칙변화성 펩타이드 및 그것의 사용 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE466869T1 (de) * | 1993-03-05 | 2010-05-15 | Epimmune Inc | Verfahren zur herstellung von immunogenen hla- a2.1-bindenden peptiden |
| JP4210735B2 (ja) * | 1996-03-21 | 2009-01-21 | ファーメクサ インコーポレイテッド | Ｈｌａ―ａ２．１結合ペプチド及びその使用 |
| WO1998004284A1 (fr) * | 1996-07-25 | 1998-02-05 | The Johns Hopkins University | Nouveaux genes de l'herpesvirus associe a la maladie de kaposi |
| US5783567A (en) * | 1997-01-22 | 1998-07-21 | Pangaea Pharmaceuticals, Inc. | Microparticles for delivery of nucleic acid |
-
2000
- 2000-02-23 WO PCT/US2000/004655 patent/WO2001062776A1/fr not_active Application Discontinuation
- 2000-02-23 MX MXPA02008219A patent/MXPA02008219A/es unknown
- 2000-02-23 AU AU2000232427A patent/AU2000232427A1/en not_active Abandoned
- 2000-02-23 CN CN00819410A patent/CN1452634A/zh active Pending
- 2000-02-23 CA CA002400215A patent/CA2400215A1/fr not_active Abandoned
- 2000-02-23 JP JP2001562557A patent/JP2003524016A/ja active Pending
- 2000-02-23 EP EP00910314A patent/EP1263775A4/fr not_active Withdrawn
- 2000-02-23 BR BR0017136-0A patent/BR0017136A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1263775A1 (fr) | 2002-12-11 |
| MXPA02008219A (es) | 2005-06-30 |
| CN1452634A (zh) | 2003-10-29 |
| EP1263775A4 (fr) | 2004-10-06 |
| WO2001062776A1 (fr) | 2001-08-30 |
| BR0017136A (pt) | 2003-02-25 |
| CA2400215A1 (fr) | 2001-08-30 |
| JP2003524016A (ja) | 2003-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |