AU1748897A - Therapeutic applications of T-BAM (CD40-L) technology to treat inflammatory kidney diseases - Google Patents
Therapeutic applications of T-BAM (CD40-L) technology to treat inflammatory kidney diseasesInfo
- Publication number
- AU1748897A AU1748897A AU17488/97A AU1748897A AU1748897A AU 1748897 A AU1748897 A AU 1748897A AU 17488/97 A AU17488/97 A AU 17488/97A AU 1748897 A AU1748897 A AU 1748897A AU 1748897 A AU1748897 A AU 1748897A
- Authority
- AU
- Australia
- Prior art keywords
- cells
- agent
- antibody
- ligand
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000026731 phosphorylation Effects 0.000 description 1
- 238000006366 phosphorylation reaction Methods 0.000 description 1
- 210000000557 podocyte Anatomy 0.000 description 1
- 229920001282 polysaccharide Chemical group 0.000 description 1
- 239000005017 polysaccharide Chemical group 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 108010031719 prolyl-serine Proteins 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000008663 renal system process Effects 0.000 description 1
- 210000005084 renal tissue Anatomy 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- DHCDFWKWKRSZHF-UHFFFAOYSA-N sulfurothioic S-acid Chemical compound OS(O)(=O)=S DHCDFWKWKRSZHF-UHFFFAOYSA-N 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000001258 synovial membrane Anatomy 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- GWIKYPMLNBTJHR-UHFFFAOYSA-M thiosulfonate group Chemical group S(=S)(=O)[O-] GWIKYPMLNBTJHR-UHFFFAOYSA-M 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 108010003137 tyrosyltyrosine Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- External Artificial Organs (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US587334 | 1990-09-24 | ||
| US58733496A | 1996-01-16 | 1996-01-16 | |
| US64147396A | 1996-05-01 | 1996-05-01 | |
| US641473 | 1996-05-01 | ||
| PCT/US1997/000668 WO1997026000A1 (fr) | 1996-01-16 | 1997-01-16 | Applications des techniques t-bam (cd40l) a des fins therapeutiques, pour le traitement d'affections renales inflammatoires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU1748897A true AU1748897A (en) | 1997-08-11 |
Family
ID=27079989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU17488/97A Abandoned AU1748897A (en) | 1996-01-16 | 1997-01-16 | Therapeutic applications of T-BAM (CD40-L) technology to treat inflammatory kidney diseases |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0874637A1 (fr) |
| JP (1) | JP2000503659A (fr) |
| AU (1) | AU1748897A (fr) |
| CA (1) | CA2243531A1 (fr) |
| MX (1) | MX9805724A (fr) |
| WO (1) | WO1997026000A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TR200001249T2 (tr) * | 1997-01-10 | 2000-11-21 | Biogen, Inc. | Anti-CD40L bileşikleri ile lupus nefritis tedavisi |
| WO2001014552A1 (fr) * | 1999-08-19 | 2001-03-01 | Kurokawa, Kiyoshi | Proteine meg-1 |
| CN1441675A (zh) | 2000-05-12 | 2003-09-10 | 贝斯以色列护理医疗中心有限公司 | 免疫抑制组合物及方法 |
| WO2018088850A2 (fr) * | 2016-11-11 | 2018-05-17 | 다이노나(주) | Anticorps se liant spécifiquement à cd40 et utilisations associée |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
-
1997
- 1997-01-16 AU AU17488/97A patent/AU1748897A/en not_active Abandoned
- 1997-01-16 JP JP9526174A patent/JP2000503659A/ja active Pending
- 1997-01-16 WO PCT/US1997/000668 patent/WO1997026000A1/fr not_active Application Discontinuation
- 1997-01-16 EP EP97904780A patent/EP0874637A1/fr not_active Withdrawn
- 1997-01-16 CA CA002243531A patent/CA2243531A1/fr not_active Abandoned
-
1998
- 1998-07-16 MX MX9805724A patent/MX9805724A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2243531A1 (fr) | 1997-07-24 |
| JP2000503659A (ja) | 2000-03-28 |
| MX9805724A (es) | 1998-10-31 |
| EP0874637A1 (fr) | 1998-11-04 |
| WO1997026000A1 (fr) | 1997-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |