AU1199000A - Shuffling of codon altered genes - Google Patents
Shuffling of codon altered genes Download PDFInfo
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- AU1199000A AU1199000A AU11990/00A AU1199000A AU1199000A AU 1199000 A AU1199000 A AU 1199000A AU 11990/00 A AU11990/00 A AU 11990/00A AU 1199000 A AU1199000 A AU 1199000A AU 1199000 A AU1199000 A AU 1199000A
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- Prior art keywords
- nucleic acid
- codon
- nucleic acids
- codon altered
- library
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
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- Wood Science & Technology (AREA)
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- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
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| US10236298P | 1998-09-29 | 1998-09-29 | |
| US60102362 | 1998-09-29 | ||
| US11772999P | 1999-01-29 | 1999-01-29 | |
| US60117729 | 1999-01-29 | ||
| US11881399P | 1999-02-05 | 1999-02-05 | |
| US60118813 | 1999-02-05 | ||
| US14104999P | 1999-06-24 | 1999-06-24 | |
| US60141049 | 1999-06-24 | ||
| PCT/US1999/022588 WO2000018906A2 (fr) | 1998-09-29 | 1999-09-28 | Rearrangement de genes modifies par codon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU1199000A true AU1199000A (en) | 2000-04-17 |
Family
ID=27493256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU11990/00A Abandoned AU1199000A (en) | 1998-09-29 | 1999-09-28 | Shuffling of codon altered genes |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1117777A2 (fr) |
| JP (1) | JP2002537758A (fr) |
| KR (1) | KR20010085850A (fr) |
| AU (1) | AU1199000A (fr) |
| CA (1) | CA2331335A1 (fr) |
| IL (1) | IL140441A0 (fr) |
| WO (1) | WO2000018906A2 (fr) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7150982B2 (en) | 1991-09-09 | 2006-12-19 | Third Wave Technologies, Inc. | RNA detection assays |
| US6759226B1 (en) | 2000-05-24 | 2004-07-06 | Third Wave Technologies, Inc. | Enzymes for the detection of specific nucleic acid sequences |
| US7045289B2 (en) | 1991-09-09 | 2006-05-16 | Third Wave Technologies, Inc. | Detection of RNA Sequences |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| DE69834938T2 (de) * | 1997-10-23 | 2007-02-01 | Nippon Institute For Biological Science, Oume | Granulozyten-kolonie-stimulierender faktor aus der katze |
| WO1999021979A1 (fr) | 1997-10-28 | 1999-05-06 | Maxygen, Inc. | Vecteurs du papillomavirus humain |
| AU1449499A (en) | 1997-10-31 | 1999-05-24 | Maxygen, Incorporated | Modification of virus tropism and host range by viral genome shuffling |
| US6902918B1 (en) | 1998-05-21 | 2005-06-07 | California Institute Of Technology | Oxygenase enzymes and screening method |
| US6337186B1 (en) | 1998-06-17 | 2002-01-08 | Maxygen, Inc. | Method for producing polynucleotides with desired properties |
| US7033781B1 (en) | 1999-09-29 | 2006-04-25 | Diversa Corporation | Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating |
| CA2396320A1 (fr) * | 2000-01-11 | 2001-07-19 | Maxygen, Inc. | Systemes integres et procedes associes de production diversifiee et de criblage |
| WO2001061028A2 (fr) * | 2000-02-16 | 2001-08-23 | Sequel Genetics, Inc. | Techniques et produits d'identification et d'analyse de sequence adn a base de peptides |
| US20110097709A1 (en) * | 2000-03-13 | 2011-04-28 | Kidd Geoffrey L | Method for modifying a nucleic acid |
| US7115403B1 (en) | 2000-05-16 | 2006-10-03 | The California Institute Of Technology | Directed evolution of galactose oxidase enzymes |
| CA2405520A1 (fr) * | 2000-05-23 | 2001-11-29 | California Institute Of Technology | Recombinaison de genes et mise au point de proteines hybrides |
| AUPQ776100A0 (en) * | 2000-05-26 | 2000-06-15 | Australian National University, The | Synthetic molecules and uses therefor |
| EP1294869A2 (fr) * | 2000-06-14 | 2003-03-26 | Diversa Corporation | Ingenierie cellulaire complete par mutagenese d'une partie substantielle d'un genome de depart, par combinaison de mutations et eventuellement repetition |
| WO2002008417A1 (fr) * | 2000-07-25 | 2002-01-31 | Takeda Chemical Industries, Ltd. | Procede de production d'une proteine de recombinaison |
| WO2002010183A1 (fr) | 2000-07-31 | 2002-02-07 | Menzel, Rolf | Compositions et procedes d'assemblage dirige de genes |
| US20030073092A1 (en) * | 2000-11-10 | 2003-04-17 | Maranas Costas D. | Modeling framework for predicting the number, type, and distribution of crossovers in directed evolution experiments |
| AU2002239855B2 (en) | 2001-01-10 | 2006-11-23 | The Penn State Research Foundation | Method and system for modeling cellular metabolism |
| US7465567B2 (en) | 2001-04-16 | 2008-12-16 | California Institute Of Technology | Peroxide-driven cytochrome P450 oxygenase variants |
| WO2002092780A2 (fr) * | 2001-05-17 | 2002-11-21 | Diversa Corporation | Nouvelles molecules de liaison a un antigene destinees a des applications therapeutiques, diagnostiques, prophylactiques, enzymatiques, industrielles et agricoles et procedes de generation et de criblage de telles molecules |
| WO2003008563A2 (fr) | 2001-07-20 | 2003-01-30 | California Institute Of Technology | Cytochrome p450 oxygenases ameliorees |
| DK1493027T3 (en) | 2002-03-01 | 2014-11-17 | Codexis Mayflower Holdings Llc | Methods, systems and software for identifying functional biomolecules |
| AU2003213846A1 (en) | 2002-03-09 | 2003-09-29 | Maxygen, Inc. | Optimization of crossover points for directed evolution |
| US9321832B2 (en) | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
| US7826975B2 (en) | 2002-07-10 | 2010-11-02 | The Penn State Research Foundation | Method for redesign of microbial production systems |
| AU2003256480B2 (en) | 2002-07-10 | 2008-03-06 | The Penn State Research Foundation | Method for determining gene knockout strategies |
| AU2003304275A1 (en) | 2002-08-06 | 2005-01-21 | Pioneer Hi-Bred International, Inc. | Ap1 amine oxidase variants |
| EP2535414B1 (fr) | 2003-04-29 | 2017-12-13 | Pioneer Hi-Bred International Inc. | Nouveaux gènes de glyphosate-N-acétyltransférase (GAT) |
| US7524664B2 (en) | 2003-06-17 | 2009-04-28 | California Institute Of Technology | Regio- and enantioselective alkane hydroxylation with modified cytochrome P450 |
| WO2005017116A2 (fr) | 2003-08-11 | 2005-02-24 | California Institute Of Technology | Variants thermostables d'oxygenase de cytochrome p450 active par l'hydrogene peroxyde et leurs procedes d'utilisation |
| US8715988B2 (en) | 2005-03-28 | 2014-05-06 | California Institute Of Technology | Alkane oxidation by modified hydroxylases |
| US11214817B2 (en) | 2005-03-28 | 2022-01-04 | California Institute Of Technology | Alkane oxidation by modified hydroxylases |
| WO2008016709A2 (fr) | 2006-08-04 | 2008-02-07 | California Institute Of Technology | Procédés et systèmes de fluoration sélective des molécules organiques |
| US8252559B2 (en) | 2006-08-04 | 2012-08-28 | The California Institute Of Technology | Methods and systems for selective fluorination of organic molecules |
| GB0617387D0 (en) * | 2006-09-04 | 2006-10-11 | Glaxo Group Ltd | Synthetic gene |
| HRP20181319T4 (hr) | 2007-03-30 | 2024-02-16 | The Research Foundation Of The State University Of New York | Oslabljeni virusi koji su korisni kao cjepiva |
| CA2990650C (fr) | 2008-05-23 | 2021-02-09 | Pioneer Hi-Bred International, Inc. | Nouveaux genes dgat permettant d'obtenir une production accrue de lipides de stockage de semences et des profils modifies d'acides gras dans des plantes a graines oleagineuses |
| US8383346B2 (en) | 2008-06-13 | 2013-02-26 | Codexis, Inc. | Combined automated parallel synthesis of polynucleotide variants |
| JP5771147B2 (ja) | 2008-09-26 | 2015-08-26 | トカジェン インコーポレーテッド | 遺伝子治療ベクターおよびシトシンデアミナーゼ |
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| US9322007B2 (en) | 2011-07-22 | 2016-04-26 | The California Institute Of Technology | Stable fungal Cel6 enzyme variants |
| KR101148191B1 (ko) * | 2011-09-27 | 2012-05-23 | 김후정 | 에리스로포이에틴-유래 펩타이드 및 그 용도 |
| US20150184173A1 (en) | 2012-05-04 | 2015-07-02 | E I Du Pont De Nemours And Company | Compositions and methods comprising sequences having meganuclease activity |
| WO2014070673A1 (fr) | 2012-10-29 | 2014-05-08 | University Of Rochester | Dérivés d'artémisinine, leurs procédés de préparation et leur utilisation en tant qu'agents antipaludiques |
| KR101600899B1 (ko) | 2012-12-11 | 2016-03-09 | 주식회사 셀레믹스 | 초병렬적 핵산 합성법을 통한 dna 라이브러리의 동시 합성 방법 |
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| BR112015023286A2 (pt) | 2013-03-14 | 2018-03-06 | Arzeda Corp | polipeptídeo recombinante com atividade da dicamba descarboxilase, construto de polinucleotídeo, célula, método de produção de uma célula hospedeira compreendendo um polinucleotídeo heterólogo que codifica um polipeptídeo tendo atividade da dicamba descarboxilase, método para descarboxilar dicamba, um derivado de dicamba ou um metabolito de dicamba, método para a detecção de um polipeptideo e método para a detecção da presença de um polinucleotideo que codifica um polipeptideo tendo atividade da dicamba descarboxilase |
| US10023877B2 (en) | 2013-03-15 | 2018-07-17 | Pioneer Hi-Bred International, Inc. | PHI-4 polypeptides and methods for their use |
| EA030896B1 (ru) | 2013-08-16 | 2018-10-31 | Пайонир Хай-Бред Интернэшнл, Инк. | Инсектицидные белки и способы их применения |
| BR122021005579B1 (pt) | 2013-09-13 | 2022-11-29 | Pioneer Hi-Bred International, Inc | Construto de dna, método de obtenção de planta transgênica, proteína de fusão, método para controlar uma população de praga de inseto, método para inibir o crescimento ou matar uma praga de inseto |
| US10544191B2 (en) | 2013-12-23 | 2020-01-28 | University Of Rochester | Methods and compositions for ribosomal synthesis of macrocyclic peptides |
| BR112016018103B1 (pt) | 2014-02-07 | 2024-01-16 | E.I. Du Pont De Nemours And Company | Polipeptídeo e seu uso, polinucleotídeo, composição, proteína de fusão, método para controlar uma população, método para inibir o crescimento, método para controlar a infestação, método para obtenção de uma planta ou célula vegetal, construto |
| CA2939156A1 (fr) | 2014-02-07 | 2015-08-13 | Pioneer Hi-Bred International, Inc. | Proteines insecticides et leurs procedes d'utilisation |
| BR112017007932A2 (pt) | 2014-10-16 | 2018-01-23 | Du Pont | proteínas inseticidas e métodos para uso das mesmas |
| WO2016144688A1 (fr) | 2015-03-11 | 2016-09-15 | Pioneer Hi Bred International Inc | Combinaisons de pip-72 insecticides et procédés d'utilisation |
| CN116333064A (zh) | 2015-05-19 | 2023-06-27 | 先锋国际良种公司 | 杀昆虫蛋白及其使用方法 |
| WO2017023486A1 (fr) | 2015-08-06 | 2017-02-09 | Pioneer Hi-Bred International, Inc. | Protéines insecticides d'origine végétale et leurs méthodes d'utilisation |
| CN108575091A (zh) | 2015-12-18 | 2018-09-25 | 先锋国际良种公司 | 杀昆虫蛋白及其使用方法 |
| EP3451837B1 (fr) | 2016-05-04 | 2021-08-25 | Pioneer Hi-Bred International, Inc. | Protéines insecticides et procédés pour les utiliser |
| EP3954202A1 (fr) | 2016-07-01 | 2022-02-16 | Pioneer Hi-Bred International, Inc. | Protéines insecticides issues de plantes et leurs procédés d'utilisation |
| WO2018048869A1 (fr) * | 2016-09-06 | 2018-03-15 | Bioventures, Llc | Compositions et procédés pour générer des vecteurs de vaccin atténués et/ou incompétents pour la réplication sans risque de réversion |
| EP3535285B1 (fr) | 2016-11-01 | 2022-04-06 | Pioneer Hi-Bred International, Inc. | Protéines insecticides et leurs procédés d'utilisation |
| BR112019012339A2 (pt) | 2016-12-14 | 2019-11-26 | Pioneer Hi Bred Int | polipeptídeo inseticida recombinante, composição, construto de dna, célula hospedeira, planta transgênica, método para inibir o crescimento ou extermínio de uma praga de inseto ou população de praga, polipeptídeo ipd093 quimérico e proteína de fusão |
| EP3558004A1 (fr) | 2016-12-22 | 2019-10-30 | Pioneer Hi-Bred International, Inc. | Protéines insecticides et leurs procédés d'utilisation |
| MX2019009371A (es) | 2017-02-08 | 2019-09-23 | Pionner Hi Bred Int Inc | Combinaciones insecticidas de proteinas insecticidas derivadas de plantas y metodos para su uso. |
| EP3363900A1 (fr) * | 2017-02-21 | 2018-08-22 | ETH Zurich | Assemblage d'adn multiplexe guidé par l'évolution de pièces d'adn, voies et géomes |
| MX2019013321A (es) | 2017-05-11 | 2020-02-10 | Pioneer Hi Bred Int | Proteinas insecticidas y metodos para su uso. |
| US11634400B2 (en) | 2017-08-19 | 2023-04-25 | University Of Rochester | Micheliolide derivatives, methods for their preparation and their use as anticancer and antiinflammatory agents |
| CN115850420A (zh) | 2018-03-14 | 2023-03-28 | 先锋国际良种公司 | 来自植物的杀昆虫蛋白及其使用方法 |
| CN111867377B (zh) | 2018-03-14 | 2023-05-23 | 先锋国际良种公司 | 来自植物的杀昆虫蛋白及其使用方法 |
| CN114040979B (zh) * | 2019-06-21 | 2024-06-28 | 国立大学法人大阪大学 | 稳定地保持外源基因的人工重组rna病毒的制作方法 |
| EP4087932A4 (fr) | 2020-01-10 | 2024-01-17 | The Regents of the University of California | Plateforme biosynthétique pour la production d'acide olivétolique et d'analogues d'acide olivétolique |
| WO2022015619A2 (fr) | 2020-07-14 | 2022-01-20 | Pioneer Hi-Bred International, Inc. | Protéines insecticides et leurs procédés d'utilisation |
| WO2023173084A1 (fr) | 2022-03-11 | 2023-09-14 | University Of Rochester | Cyclopepticorps et leurs utilisations |
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| IL99553A0 (en) * | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing oligonucleotides linked to expression elements,a kit for the preparation of vectors useful for the expression of a diverse population of random peptides and methods utilizing the same |
| US5837458A (en) * | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| AU4597197A (en) * | 1996-09-27 | 1998-04-17 | Introgene B.V. | Methods for optimization of gene therapy by recursive sequence shuffling and selection |
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- 1999-09-28 EP EP99969739A patent/EP1117777A2/fr not_active Withdrawn
- 1999-09-28 WO PCT/US1999/022588 patent/WO2000018906A2/fr not_active Application Discontinuation
- 1999-09-28 AU AU11990/00A patent/AU1199000A/en not_active Abandoned
- 1999-09-28 CA CA002331335A patent/CA2331335A1/fr not_active Abandoned
- 1999-09-28 IL IL14044199A patent/IL140441A0/xx unknown
- 1999-09-28 KR KR1020017003873A patent/KR20010085850A/ko not_active Application Discontinuation
- 1999-09-28 JP JP2000572353A patent/JP2002537758A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000018906A3 (fr) | 2000-10-26 |
| IL140441A0 (en) | 2002-02-10 |
| WO2000018906A2 (fr) | 2000-04-06 |
| EP1117777A2 (fr) | 2001-07-25 |
| CA2331335A1 (fr) | 2000-04-06 |
| KR20010085850A (ko) | 2001-09-07 |
| JP2002537758A (ja) | 2002-11-12 |
| WO2000018906A9 (fr) | 2000-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK5 | Application lapsed section 142(2)(e) - patent request and compl. specification not accepted |