ATE99322T1 - Loesungssynthese eines oktapeptids. - Google Patents
Loesungssynthese eines oktapeptids.Info
- Publication number
- ATE99322T1 ATE99322T1 AT88309307T AT88309307T ATE99322T1 AT E99322 T1 ATE99322 T1 AT E99322T1 AT 88309307 T AT88309307 T AT 88309307T AT 88309307 T AT88309307 T AT 88309307T AT E99322 T1 ATE99322 T1 AT E99322T1
- Authority
- AT
- Austria
- Prior art keywords
- leu
- formula
- protecting group
- phe
- gly
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- NYJVPTKMDYSZDU-MRNVWEPHSA-N (2s)-2-[[(2s)-2-[[(2s)-6-amino-2-[[(2s)-1-[2-[[(2s)-2-[[(2s)-2-[[(2s)-2-amino-4-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-3-carboxypropanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid Chemical compound CC(C)C[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CC(C)C)C(O)=O)CC1=CC=CC=C1 NYJVPTKMDYSZDU-MRNVWEPHSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000002992 thymic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C07K7/065—Thymic humoral factor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878723485A GB8723485D0 (en) | 1987-10-07 | 1987-10-07 | Solution synthesis of octapeptide |
| EP88309307A EP0311392B1 (de) | 1987-10-07 | 1988-10-06 | Lösungssynthese eines Oktapeptids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE99322T1 true ATE99322T1 (de) | 1994-01-15 |
Family
ID=10624895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88309307T ATE99322T1 (de) | 1987-10-07 | 1988-10-06 | Loesungssynthese eines oktapeptids. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0311392B1 (de) |
| JP (1) | JPH01128999A (de) |
| AT (1) | ATE99322T1 (de) |
| AU (1) | AU613667B2 (de) |
| DE (1) | DE3886656T2 (de) |
| ES (1) | ES2061679T3 (de) |
| GB (1) | GB8723485D0 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8723484D0 (en) * | 1987-10-07 | 1987-11-11 | Erba Farmitalia | Preparing octapeptide |
| IL106214A (en) * | 1993-07-01 | 1998-12-06 | Yeda Res & Dev | Thf-gamma2 analogs and pharmaceutical compositions comprising them |
| MX339762B (es) * | 2011-09-28 | 2016-05-27 | Univ Autonoma Del Estado De Morelos | Metalopeptidos inmunomoduladores (immp) y composiciones que los contienen. |
| CN112812152B (zh) * | 2015-06-23 | 2022-09-02 | 首都医科大学 | Glu-Leu-Phe-Tyr-Val五肽的合成及抗炎应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8723484D0 (en) * | 1987-10-07 | 1987-11-11 | Erba Farmitalia | Preparing octapeptide |
-
1987
- 1987-10-07 GB GB878723485A patent/GB8723485D0/en active Pending
-
1988
- 1988-10-04 AU AU23390/88A patent/AU613667B2/en not_active Ceased
- 1988-10-06 JP JP63252857A patent/JPH01128999A/ja active Pending
- 1988-10-06 DE DE88309307T patent/DE3886656T2/de not_active Expired - Fee Related
- 1988-10-06 ES ES88309307T patent/ES2061679T3/es not_active Expired - Lifetime
- 1988-10-06 EP EP88309307A patent/EP0311392B1/de not_active Expired - Lifetime
- 1988-10-06 AT AT88309307T patent/ATE99322T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE3886656T2 (de) | 1994-04-28 |
| AU2339088A (en) | 1989-04-13 |
| AU613667B2 (en) | 1991-08-08 |
| GB8723485D0 (en) | 1987-11-11 |
| EP0311392B1 (de) | 1993-12-29 |
| JPH01128999A (ja) | 1989-05-22 |
| EP0311392A2 (de) | 1989-04-12 |
| ES2061679T3 (es) | 1994-12-16 |
| DE3886656D1 (de) | 1994-02-10 |
| EP0311392A3 (en) | 1990-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |