ATE969T1 - Von desoxystreptamin abgeleitete aminoglykoside und ihre salze, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zusammensetzungen. - Google Patents

Von desoxystreptamin abgeleitete aminoglykoside und ihre salze, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zusammensetzungen.

Info

Publication number
ATE969T1
ATE969T1 AT79400541T AT79400541T ATE969T1 AT E969 T1 ATE969 T1 AT E969T1 AT 79400541 T AT79400541 T AT 79400541T AT 79400541 T AT79400541 T AT 79400541T AT E969 T1 ATE969 T1 AT E969T1
Authority
AT
Austria
Prior art keywords
preparation
salts
desoxystreptamine
processes
pharmaceutical compositions
Prior art date
Application number
AT79400541T
Other languages
German (de)
English (en)
Inventor
Jean-Claude Gasc
Claude Rettien
Original Assignee
Roussel-Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel-Uclaf filed Critical Roussel-Uclaf
Application granted granted Critical
Publication of ATE969T1 publication Critical patent/ATE969T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT79400541T 1978-09-06 1979-07-31 Von desoxystreptamin abgeleitete aminoglykoside und ihre salze, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zusammensetzungen. ATE969T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7825604A FR2435481A1 (fr) 1978-09-06 1978-09-06 Nouveaux aminoglycosides derives de la desoxystreptamine et leurs sels, procede de preparation et application a titre de medicaments
EP79400541A EP0008965B1 (fr) 1978-09-06 1979-07-31 Nouveaux aminoglycosides dérivés de la désoxystreptamine et leurs sels, leur procédé de préparation, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number Publication Date
ATE969T1 true ATE969T1 (de) 1982-05-15

Family

ID=9212381

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79400541T ATE969T1 (de) 1978-09-06 1979-07-31 Von desoxystreptamin abgeleitete aminoglykoside und ihre salze, verfahren zu ihrer herstellung und die sie enthaltenden pharmazeutischen zusammensetzungen.

Country Status (11)

Country Link
US (1) US4242331A (it)
EP (1) EP0008965B1 (it)
JP (1) JPS5538378A (it)
AT (1) ATE969T1 (it)
AU (1) AU524737B2 (it)
CA (1) CA1133476A (it)
DE (1) DE2962697D1 (it)
FR (1) FR2435481A1 (it)
HU (1) HU180288B (it)
IE (1) IE49299B1 (it)
ZA (1) ZA794155B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1001869A3 (fr) * 1988-10-12 1990-04-03 Franz Legros Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US5442047A (en) * 1991-12-04 1995-08-15 Schering Corporation Process for preparing isepamicin
IT1237490B (it) * 1989-09-22 1993-06-07 Chementecno S R L Monza Milano Procedimento per la sintesi della 1 n (s delta ammino alfa idrossibutirril)kamanycin a basato sul trattamento della 1 n (s delta benzilossicarbonilammino alfa idrossibutirril) 3,6' di n benzilossicarbonilkanamycin a con acido formico
US7794713B2 (en) 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US7862812B2 (en) 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001208A (en) * 1972-10-06 1977-01-04 Zaidan Hojin Biseibutsu Kagaku Kenkyo Kai 1-N-[(S)-α-hydroxy-ω-aminoacyl]
PH12960A (en) * 1974-03-19 1979-10-19 Scherico Ltd Derivatives of 4,6-di-(aminoglycosyl)-1,3-diaminocy-clitols and pharmaceutical compositions thereof
FR2290908A1 (fr) * 1974-11-13 1976-06-11 Roussel Uclaf Nouveau derive aminoglycosidique et ses sels, leur procede de preparation et leur application comme medicaments
FR2318648A1 (fr) * 1975-07-23 1977-02-18 Roussel Uclaf Nouveau derive de la desoxystreptamine et des sels, leur procede de preparation et leur application comme medicaments
FR2358156A1 (fr) * 1976-03-31 1978-02-10 Roussel Uclaf Nouvel analogue de la desoxystreptamine et ses sels, leur procede de preparation et leur application comme medicaments
US4146617A (en) * 1976-07-15 1979-03-27 Roussel Uclaf Desoxystreptamine derivatives, salts, pharmaceutical compositions and method of use

Also Published As

Publication number Publication date
EP0008965A2 (fr) 1980-03-19
JPS6340196B2 (it) 1988-08-10
FR2435481B1 (it) 1981-07-24
IE791693L (en) 1980-03-06
JPS5538378A (en) 1980-03-17
AU524737B2 (en) 1982-09-30
FR2435481A1 (fr) 1980-04-04
DE2962697D1 (en) 1982-06-24
CA1133476A (fr) 1982-10-12
EP0008965A3 (en) 1980-04-02
HU180288B (en) 1983-02-28
ZA794155B (en) 1980-08-27
AU5058479A (en) 1980-03-13
US4242331A (en) 1980-12-30
EP0008965B1 (fr) 1982-05-05
IE49299B1 (en) 1985-09-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EETV Partially withdrawn
REN Ceased due to non-payment of the annual fee