ATE96318T1 - Acylaminoalkylpyridinamide als inhibitoren der tumormetastasierung. - Google Patents

Acylaminoalkylpyridinamide als inhibitoren der tumormetastasierung.

Info

Publication number
ATE96318T1
ATE96318T1 AT89122191T AT89122191T ATE96318T1 AT E96318 T1 ATE96318 T1 AT E96318T1 AT 89122191 T AT89122191 T AT 89122191T AT 89122191 T AT89122191 T AT 89122191T AT E96318 T1 ATE96318 T1 AT E96318T1
Authority
AT
Austria
Prior art keywords
tumor metastasis
group
halo
chem
animal
Prior art date
Application number
AT89122191T
Other languages
English (en)
Inventor
George Charles Fuller
George Reilly Martin
Richard August Mueller
Reuven Reich
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE96318T1 publication Critical patent/ATE96318T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT89122191T 1988-12-02 1989-12-01 Acylaminoalkylpyridinamide als inhibitoren der tumormetastasierung. ATE96318T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/279,186 US5030642A (en) 1988-12-02 1988-12-02 Acylaminoalkylpyridineamides as inhibitors of metastasis
EP89122191A EP0372409B1 (de) 1988-12-02 1989-12-01 Acylaminoalkylpyridinamide als Inhibitoren der Tumormetastasierung

Publications (1)

Publication Number Publication Date
ATE96318T1 true ATE96318T1 (de) 1993-11-15

Family

ID=23067997

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89122191T ATE96318T1 (de) 1988-12-02 1989-12-01 Acylaminoalkylpyridinamide als inhibitoren der tumormetastasierung.

Country Status (7)

Country Link
US (1) US5030642A (de)
EP (1) EP0372409B1 (de)
JP (1) JP2840337B2 (de)
AT (1) ATE96318T1 (de)
CA (1) CA2004443A1 (de)
DE (1) DE68910282T2 (de)
ES (1) ES2059685T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2069904T3 (es) * 1990-09-07 1995-05-16 Searle & Co Tioeteramidas fenolicas utiles como inhibidores de 5-lipoxigenasa.
US6071949A (en) * 1995-03-14 2000-06-06 The United States Of America As Represented By The Department Of Health And Human Services Use of lipoxygenase inhibitors as anti-cancer therapeutic and intervention agents
FR2747568B1 (fr) * 1996-04-17 1999-09-17 Oreal Utilisation d'au moins un inhibiteur de lipoxygenase et d'au moins un inhibiteur de cyclo-oxygenase pour modifier la pousse des poils et/ou des cheveux

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029812A (en) * 1976-02-18 1977-06-14 The Dow Chemical Company Novel hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)thio carboxamides
US4663333A (en) * 1985-02-04 1987-05-05 G. D. Searle & Co. Acylaminoalkylpyridines ad use in treatment of inflammation and allergy reactions

Also Published As

Publication number Publication date
JPH02243625A (ja) 1990-09-27
DE68910282T2 (de) 1994-03-10
EP0372409A2 (de) 1990-06-13
EP0372409B1 (de) 1993-10-27
DE68910282D1 (de) 1993-12-02
CA2004443A1 (en) 1990-06-02
JP2840337B2 (ja) 1998-12-24
US5030642A (en) 1991-07-09
ES2059685T3 (es) 1994-11-16
EP0372409A3 (de) 1991-05-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee