ATE90078T1 - Tetrahydropyridin-oxime, verfahren zu ihrer herstellung und ihre verwendung als cholinergische mittel. - Google Patents
Tetrahydropyridin-oxime, verfahren zu ihrer herstellung und ihre verwendung als cholinergische mittel.Info
- Publication number
- ATE90078T1 ATE90078T1 AT88105296T AT88105296T ATE90078T1 AT E90078 T1 ATE90078 T1 AT E90078T1 AT 88105296 T AT88105296 T AT 88105296T AT 88105296 T AT88105296 T AT 88105296T AT E90078 T1 ATE90078 T1 AT E90078T1
- Authority
- AT
- Austria
- Prior art keywords
- oximes
- production
- tetrahydropyridin
- processes
- cholinergic agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/032,839 US4798841A (en) | 1987-03-31 | 1987-03-31 | Tetrahydropyridine oxime cholinergic agents and method of treatment |
EP88105296A EP0291673B1 (de) | 1987-03-31 | 1988-03-31 | Tetrahydropyridin-oxime, Verfahren zu ihrer Herstellung und ihre Verwendung als cholinergische Mittel |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE90078T1 true ATE90078T1 (de) | 1993-06-15 |
Family
ID=21867098
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88105296T ATE90078T1 (de) | 1987-03-31 | 1988-03-31 | Tetrahydropyridin-oxime, verfahren zu ihrer herstellung und ihre verwendung als cholinergische mittel. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4798841A (de) |
EP (1) | EP0291673B1 (de) |
JP (1) | JP2714391B2 (de) |
AT (1) | ATE90078T1 (de) |
CA (1) | CA1341139C (de) |
DE (1) | DE3881439T2 (de) |
ES (1) | ES2054723T3 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1203971B (it) * | 1987-04-24 | 1989-02-23 | Roussel Maestretti Spa | Derivati di 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro applicazione come medicamenti |
EP0338723B1 (de) * | 1988-04-15 | 1993-08-04 | Beecham Group Plc | Chemische Verbindungen |
SG48315A1 (en) * | 1989-04-13 | 1998-04-17 | Beecham Group Plc | Novel compounds |
US5594000A (en) * | 1989-06-21 | 1997-01-14 | Astra Ab | Spirofurane derivatives |
US5075317A (en) * | 1989-06-21 | 1991-12-24 | Fisons Corporation | Spirofurane derivatives |
IT1240603B (it) * | 1990-03-14 | 1993-12-17 | Roussel Maestretti Spa | Derivati della 1,2,5,6-tetraidropiridina 3- carbossaldeide ossima, loro procedimento di preparazione e loro impiego come sostanza medicinale |
IE912239A1 (en) * | 1990-07-24 | 1992-01-29 | Akzo Nv | Tetrahydropyridinyldibenzazepine derivatives |
DE69129114T2 (de) * | 1990-08-24 | 1998-10-08 | Beecham Group Plc | Azabicyclische verbindungen, verfahren und zwischenprodukte zu ihrer herstellung und pharmazeutische zusammensetzungen die diese enthalten |
GB9019095D0 (en) * | 1990-09-01 | 1990-10-17 | Beecham Group Plc | Novel compounds |
US5356914A (en) * | 1990-10-12 | 1994-10-18 | Beecham Group P.L.C. | 1,2,5,6-tetrahydropyridine oxime derivatives |
US5208343A (en) * | 1992-03-24 | 1993-05-04 | Warner-Lambert Company | Tetrahydropyridine oxime compounds |
TW266206B (de) * | 1993-04-28 | 1995-12-21 | Takeda Pharm Industry Co Ltd | |
ATE189814T1 (de) * | 1996-04-15 | 2000-03-15 | Takeda Chemical Industries Ltd | Hydroxypyridin-derivate, ihre herstellung und ihre pharmazeutische verwendung |
EP1554572B1 (de) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
DE10305391A1 (de) * | 2003-02-11 | 2004-08-19 | Aventis Pharma Deutschland Gmbh | Verfahren zur Herstellung von Pyridin-substituierten Aminoketal-Derivaten |
US6916934B2 (en) | 2003-02-11 | 2005-07-12 | Aventis Pharma Deutschland Gmbh | Process for preparing pyridine-substituted amino ketal derivatives |
CN101287411B (zh) | 2005-04-28 | 2013-03-06 | 普罗秋斯生物医学公司 | 药物信息系统及其用途 |
CA2663377A1 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
MX347901B (es) | 2008-03-27 | 2017-05-18 | Chase Pharmaceuticals Corp | Uso y composicion para tratar la demencia. |
NZ594310A (en) | 2009-02-20 | 2014-02-28 | To Bbb Holding B V | Glutathione-based drug delivery system |
MX2011011833A (es) | 2009-05-06 | 2012-01-27 | Lab Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de partículas de fosfato de calcio-agente activo y métodos para utilizar las mismas. |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3004979A (en) * | 1961-10-17 | Oximes of certain tetrahydropyridine | ||
JPS511638A (ja) * | 1974-06-27 | 1976-01-08 | Fujisawa Pharmaceutical Co | Shokubutsuseichochoseizai |
IL81610A (en) * | 1986-02-27 | 1990-12-23 | Roussel Uclaf | Derivatives of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime,their preparation and pharmaceutical compositions containing them |
US4710508A (en) * | 1986-12-08 | 1987-12-01 | Warner-Lambert Company | O-substituted tetrahydropyridine oxime cholinergic agents |
-
1987
- 1987-03-31 US US07/032,839 patent/US4798841A/en not_active Expired - Lifetime
-
1988
- 1988-02-16 CA CA000559032A patent/CA1341139C/en not_active Expired - Fee Related
- 1988-03-30 JP JP63074845A patent/JP2714391B2/ja not_active Expired - Fee Related
- 1988-03-31 DE DE8888105296T patent/DE3881439T2/de not_active Expired - Fee Related
- 1988-03-31 EP EP88105296A patent/EP0291673B1/de not_active Expired - Lifetime
- 1988-03-31 AT AT88105296T patent/ATE90078T1/de not_active IP Right Cessation
- 1988-03-31 ES ES88105296T patent/ES2054723T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0291673B1 (de) | 1993-06-02 |
JPS63258457A (ja) | 1988-10-25 |
US4798841A (en) | 1989-01-17 |
DE3881439T2 (de) | 1993-09-23 |
CA1341139C (en) | 2000-11-14 |
EP0291673A1 (de) | 1988-11-23 |
JP2714391B2 (ja) | 1998-02-16 |
ES2054723T3 (es) | 1994-08-16 |
DE3881439D1 (de) | 1993-07-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |