ATE8788T1 - Verfahren zur herstellung 3-bromosubstituierter desacetoxycephalosporansaeure-sulfoxyd-derivate. - Google Patents
Verfahren zur herstellung 3-bromosubstituierter desacetoxycephalosporansaeure-sulfoxyd-derivate.Info
- Publication number
- ATE8788T1 ATE8788T1 AT81200174T AT81200174T ATE8788T1 AT E8788 T1 ATE8788 T1 AT E8788T1 AT 81200174 T AT81200174 T AT 81200174T AT 81200174 T AT81200174 T AT 81200174T AT E8788 T1 ATE8788 T1 AT E8788T1
- Authority
- AT
- Austria
- Prior art keywords
- bromosubstituted
- preparation
- sulfoxide derivatives
- desacetoxycephalosporanic acid
- acid sulfoxide
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000003462 sulfoxides Chemical class 0.000 title 1
- -1 deacetoxycephalosporanic acid sulphoxide derivatives Chemical class 0.000 abstract 3
- NVIAYEIXYQCDAN-CLZZGJSISA-N 7beta-aminodeacetoxycephalosporanic acid Chemical compound S1CC(C)=C(C(O)=O)N2C(=O)[C@@H](N)[C@@H]12 NVIAYEIXYQCDAN-CLZZGJSISA-N 0.000 abstract 1
- ATTZFSUZZUNHBP-UHFFFAOYSA-N Piperonyl sulfoxide Chemical compound CCCCCCCCS(=O)C(C)CC1=CC=C2OCOC2=C1 ATTZFSUZZUNHBP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1896—Compounds having one or more Si-O-acyl linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Catalysts (AREA)
- Lubricants (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Saccharide Compounds (AREA)
- Pyrrole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8004925A GB2069482B (en) | 1980-02-14 | 1980-02-14 | Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives |
| EP81200174A EP0034394B1 (de) | 1980-02-14 | 1981-02-13 | Verfahren zur Herstellung 3-bromosubstituierter Desacetoxycephalosporansäure-Sulfoxyd-Derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE8788T1 true ATE8788T1 (de) | 1984-08-15 |
Family
ID=10511335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81200174T ATE8788T1 (de) | 1980-02-14 | 1981-02-13 | Verfahren zur herstellung 3-bromosubstituierter desacetoxycephalosporansaeure-sulfoxyd-derivate. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4366315A (de) |
| EP (1) | EP0034394B1 (de) |
| JP (1) | JPS56128788A (de) |
| KR (1) | KR840002161B1 (de) |
| AT (1) | ATE8788T1 (de) |
| AU (1) | AU538523B2 (de) |
| CA (1) | CA1177065A (de) |
| DE (1) | DE3165149D1 (de) |
| DK (1) | DK55981A (de) |
| ES (1) | ES8202025A1 (de) |
| FI (1) | FI71938C (de) |
| GB (1) | GB2069482B (de) |
| GR (1) | GR73846B (de) |
| HU (1) | HU185239B (de) |
| IE (1) | IE50865B1 (de) |
| IL (1) | IL61988A (de) |
| NO (1) | NO160078C (de) |
| PT (1) | PT72444B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU566944B2 (en) * | 1983-10-07 | 1987-11-05 | Gist-Brocades N.V. | Preparation of 3-cephem derivatives |
| JPS60169486A (ja) * | 1984-02-10 | 1985-09-02 | Yamanouchi Pharmaceut Co Ltd | ７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法 |
| US4578473A (en) * | 1985-04-15 | 1986-03-25 | Warner-Lambert Company | Process for quinoline-3-carboxylic acid antibacterial agents |
| US5604222A (en) * | 1993-12-27 | 1997-02-18 | Lupin Laboratories, Ltd. | Method for the preparation of 2-chloro sulfinyl azetidinones |
| US5578721A (en) * | 1994-07-11 | 1996-11-26 | Lupin Laboratories Limited | Process for preparation of 3-exomethylene cepham sulfoxide esters |
| US7525659B2 (en) * | 2003-01-15 | 2009-04-28 | Negevtech Ltd. | System for detection of water defects |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1326531A (en) * | 1969-08-26 | 1973-08-15 | Glaxo Lab Ltd | Cephalosporin compounds |
| US3922268A (en) * | 1969-12-08 | 1975-11-25 | Lilly Co Eli | 3-Halomethyl-{66 {hu 3-Cephalosporin esters |
| BE789291A (fr) | 1971-09-30 | 1973-03-26 | Bristol Myers Co | Composes intermediaires pour la synthese des cephalosporines |
| US4182870A (en) * | 1977-09-07 | 1980-01-08 | Gist-Brocades N.V. | Preparation of 3-bromomethyl-3-cephem sulfoxides |
| IL59395A (en) * | 1979-03-06 | 1983-07-31 | Gist Brocades Nv | Bromo-substituted deacetoxycephalosporin derivatives and their preparation |
| US4223135A (en) * | 1979-03-19 | 1980-09-16 | Bristol-Myers Company | Production of cephalosporins |
-
1980
- 1980-02-14 GB GB8004925A patent/GB2069482B/en not_active Expired
-
1981
- 1981-01-22 AU AU66549/81A patent/AU538523B2/en not_active Ceased
- 1981-01-26 IL IL61988A patent/IL61988A/xx unknown
- 1981-02-03 PT PT72444A patent/PT72444B/pt not_active IP Right Cessation
- 1981-02-10 DK DK55981A patent/DK55981A/da not_active Application Discontinuation
- 1981-02-10 NO NO810452A patent/NO160078C/no unknown
- 1981-02-12 HU HU81348A patent/HU185239B/hu not_active IP Right Cessation
- 1981-02-12 KR KR1019810000422A patent/KR840002161B1/ko active
- 1981-02-12 FI FI810431A patent/FI71938C/fi not_active IP Right Cessation
- 1981-02-12 GR GR64110A patent/GR73846B/el unknown
- 1981-02-13 US US06/234,545 patent/US4366315A/en not_active Expired - Fee Related
- 1981-02-13 CA CA000370844A patent/CA1177065A/en not_active Expired
- 1981-02-13 ES ES499412A patent/ES8202025A1/es not_active Expired
- 1981-02-13 JP JP1998581A patent/JPS56128788A/ja active Granted
- 1981-02-13 IE IE286/81A patent/IE50865B1/en not_active IP Right Cessation
- 1981-02-13 AT AT81200174T patent/ATE8788T1/de active
- 1981-02-13 EP EP81200174A patent/EP0034394B1/de not_active Expired
- 1981-02-13 DE DE8181200174T patent/DE3165149D1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK55981A (da) | 1981-08-15 |
| US4366315A (en) | 1982-12-28 |
| KR830005241A (ko) | 1983-08-03 |
| PT72444B (en) | 1982-01-29 |
| JPS56128788A (en) | 1981-10-08 |
| NO160078B (no) | 1988-11-28 |
| FI810431L (fi) | 1981-08-15 |
| ES499412A0 (es) | 1982-01-01 |
| CA1177065A (en) | 1984-10-30 |
| FI71938C (fi) | 1987-03-09 |
| IL61988A (en) | 1984-03-30 |
| KR840002161B1 (ko) | 1984-11-24 |
| IE50865B1 (en) | 1986-08-06 |
| HU185239B (en) | 1984-12-28 |
| EP0034394A2 (de) | 1981-08-26 |
| IE810286L (en) | 1981-08-14 |
| IL61988A0 (en) | 1981-02-27 |
| AU538523B2 (en) | 1984-08-16 |
| JPS6360759B2 (de) | 1988-11-25 |
| AU6654981A (en) | 1981-08-20 |
| EP0034394B1 (de) | 1984-08-01 |
| EP0034394A3 (en) | 1981-11-25 |
| PT72444A (en) | 1981-03-01 |
| GB2069482B (en) | 1984-04-04 |
| GR73846B (de) | 1984-05-07 |
| ES8202025A1 (es) | 1982-01-01 |
| FI71938B (fi) | 1986-11-28 |
| GB2069482A (en) | 1981-08-26 |
| NO810452L (no) | 1981-08-17 |
| NO160078C (no) | 1989-03-08 |
| DE3165149D1 (en) | 1984-09-06 |
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