ATE87614T1 - Methoden zur verwendung von 2-isopropyl-2phenylaminovaleriansaeurenitrilen als immunosupressoren und vasodilatoren. - Google Patents

Methoden zur verwendung von 2-isopropyl-2phenylaminovaleriansaeurenitrilen als immunosupressoren und vasodilatoren.

Info

Publication number
ATE87614T1
ATE87614T1 AT90125244T AT90125244T ATE87614T1 AT E87614 T1 ATE87614 T1 AT E87614T1 AT 90125244 T AT90125244 T AT 90125244T AT 90125244 T AT90125244 T AT 90125244T AT E87614 T1 ATE87614 T1 AT E87614T1
Authority
AT
Austria
Prior art keywords
cyclosporin
isopropyl
immunosupressors
vasodilators
methods
Prior art date
Application number
AT90125244T
Other languages
English (en)
Inventor
Liang Chi-Dean
Richard August Mueller
Kearn John P Mc
Terry B Strom
Kenneth J Wieder
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE87614T1 publication Critical patent/ATE87614T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C07C255/43—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms the carbon skeleton being further substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90125244T 1989-12-21 1990-12-21 Methoden zur verwendung von 2-isopropyl-2phenylaminovaleriansaeurenitrilen als immunosupressoren und vasodilatoren. ATE87614T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45600789A 1989-12-21 1989-12-21
EP90125244A EP0434094B1 (de) 1989-12-21 1990-12-21 Methoden zur Verwendung von 2-Isopropyl-2-phenylaminovaleriansäurenitrilen als Immunosupressoren und Vasodilatoren

Publications (1)

Publication Number Publication Date
ATE87614T1 true ATE87614T1 (de) 1993-04-15

Family

ID=23811068

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90125244T ATE87614T1 (de) 1989-12-21 1990-12-21 Methoden zur verwendung von 2-isopropyl-2phenylaminovaleriansaeurenitrilen als immunosupressoren und vasodilatoren.

Country Status (10)

Country Link
EP (1) EP0434094B1 (de)
JP (1) JPH04210632A (de)
AT (1) ATE87614T1 (de)
CA (1) CA2033038A1 (de)
DE (1) DE69001240T2 (de)
DK (1) DK0434094T3 (de)
ES (1) ES2054207T3 (de)
GR (1) GR3008320T3 (de)
IE (1) IE64870B1 (de)
PT (1) PT96283A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2498047T3 (es) 2007-06-20 2014-09-24 Milestone Pharmaceuticals Inc. Bloqueantes de los canales de calcio de fenilalquilamina de acción corta y usos de los mismos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3642331A1 (de) * 1986-12-11 1988-06-23 Basf Ag Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0434094A1 (de) 1991-06-26
PT96283A (pt) 1991-09-30
GR3008320T3 (de) 1993-09-30
IE904627A1 (en) 1991-07-17
CA2033038A1 (en) 1991-06-22
IE64870B1 (en) 1995-09-20
DK0434094T3 (da) 1993-08-16
JPH04210632A (ja) 1992-07-31
DE69001240T2 (de) 1993-08-05
EP0434094B1 (de) 1993-03-31
DE69001240D1 (de) 1993-05-06
ES2054207T3 (es) 1994-08-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee