ES2054207T3 - Metodos de uso de 2-isopropil-2-fenilaminovaleronitrilos como inmunosupresores y vasodilatadores. - Google Patents
Metodos de uso de 2-isopropil-2-fenilaminovaleronitrilos como inmunosupresores y vasodilatadores.Info
- Publication number
- ES2054207T3 ES2054207T3 ES90125244T ES90125244T ES2054207T3 ES 2054207 T3 ES2054207 T3 ES 2054207T3 ES 90125244 T ES90125244 T ES 90125244T ES 90125244 T ES90125244 T ES 90125244T ES 2054207 T3 ES2054207 T3 ES 2054207T3
- Authority
- ES
- Spain
- Prior art keywords
- cyclosporin
- phenylaminovaleronitrils
- isopropil
- vasodilators
- immunosuppressants
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
- C07C255/43—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
VALERONITRILOS DE 2-ISOPROPIL-2-FENIL-5-(FENETIL AMINO) SUSTITUIDOS SON UTILIZADOS COMO INMUNOSUPRESORES EN UN METODO PARA EL TRATAMIENTO DEL RECHAZO DE ORGANOS TRANSPLANTADO, BIEN POR SI SOLOS O JUNTO CON LA ADMINISTRACION DE CICLOPORINA DE MANERA SINERGISTICA QUE PERMITE MENORES DOSIS DE CICLOSPORINA QUE LAS QUE SE SUMINISTRARIAN SI LA CICLOSPORINA FUERA ADMINISTRADA POR SI SOLA. EL MECANISMO DE ACCION ESTA PENSADO PARA QUE SEA INDEPENDIENTE DEL CANAL DE CALCIO CARDIOVASCULAR QUE BLOQUEA LA ACTIVIDAD DE LOS COMPUESTOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45600789A | 1989-12-21 | 1989-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2054207T3 true ES2054207T3 (es) | 1994-08-01 |
Family
ID=23811068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES90125244T Expired - Lifetime ES2054207T3 (es) | 1989-12-21 | 1990-12-21 | Metodos de uso de 2-isopropil-2-fenilaminovaleronitrilos como inmunosupresores y vasodilatadores. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0434094B1 (es) |
JP (1) | JPH04210632A (es) |
AT (1) | ATE87614T1 (es) |
CA (1) | CA2033038A1 (es) |
DE (1) | DE69001240T2 (es) |
DK (1) | DK0434094T3 (es) |
ES (1) | ES2054207T3 (es) |
GR (1) | GR3008320T3 (es) |
IE (1) | IE64870B1 (es) |
PT (1) | PT96283A (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100190852A1 (en) | 2007-06-20 | 2010-07-29 | Milestone Pharmaceuticals Inc. | Short acting phenylalkylamine calcium channel blockers and uses thereof |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3642331A1 (de) * | 1986-12-11 | 1988-06-23 | Basf Ag | Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel |
-
1990
- 1990-12-20 IE IE462790A patent/IE64870B1/en not_active IP Right Cessation
- 1990-12-20 PT PT96283A patent/PT96283A/pt not_active Application Discontinuation
- 1990-12-21 JP JP2419052A patent/JPH04210632A/ja not_active Withdrawn
- 1990-12-21 CA CA002033038A patent/CA2033038A1/en not_active Abandoned
- 1990-12-21 AT AT90125244T patent/ATE87614T1/de not_active IP Right Cessation
- 1990-12-21 ES ES90125244T patent/ES2054207T3/es not_active Expired - Lifetime
- 1990-12-21 DK DK90125244.5T patent/DK0434094T3/da active
- 1990-12-21 DE DE9090125244T patent/DE69001240T2/de not_active Expired - Fee Related
- 1990-12-21 EP EP90125244A patent/EP0434094B1/en not_active Expired - Lifetime
-
1993
- 1993-06-30 GR GR930400669T patent/GR3008320T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69001240T2 (de) | 1993-08-05 |
IE904627A1 (en) | 1991-07-17 |
DK0434094T3 (da) | 1993-08-16 |
GR3008320T3 (es) | 1993-09-30 |
DE69001240D1 (de) | 1993-05-06 |
JPH04210632A (ja) | 1992-07-31 |
CA2033038A1 (en) | 1991-06-22 |
ATE87614T1 (de) | 1993-04-15 |
IE64870B1 (en) | 1995-09-20 |
EP0434094A1 (en) | 1991-06-26 |
PT96283A (pt) | 1991-09-30 |
EP0434094B1 (en) | 1993-03-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL85746A0 (en) | Preparation of t cells and t cell membrane for use in autoimmune diseases | |
DE236684T1 (de) | Galanthamin oder dessen analoge zur behandlung der alzheimerschen krankheit. | |
DK0735890T3 (da) | Blandinger af 2',3'-dideoxyinosin og hydroxycarbamid til hæmning af retroviral spredning | |
NO844579L (no) | Enzymresistente immunomodulerende peptider. | |
ATE211384T1 (de) | Verwendung von adenosinantagonisten zur vorbeugung und behandlung von pankreatitis und ulcera | |
ATE105482T1 (de) | Behandlung von krebs mit somatostatin und mit analogen davon. | |
DE69430951D1 (de) | Zusammensetzung enthaltend bradykinin zum selektiven offnen von anormalen gehirngewebes kapillaren | |
DK0668769T3 (da) | Egebarkekstrakt-relaterede syntetiske sammensætninger og fremgangsmåde til deres anvendelse | |
DK90089D0 (da) | Hudbehandlingspraeparat | |
RU94020410A (ru) | Способ лечения или профилактики рвоты у млекопитающих и человека с использованием некоторых хинуклидиновых, пиперидиновых, азанорборнановых, этилендиаминовых производных и родственных им соединений | |
DE3873428D1 (de) | Antiinflammatorisch wirkende furanone. | |
RU92016277A (ru) | Микробиоциды | |
ATE78171T1 (de) | Gangliosidgemisch zur verwendung als therapeutisches hilfsmittel zur schmerzunterdrueckung bei peripheren neuropathien. | |
ATE49115T1 (de) | Haarbehandlungsmittel. | |
NO894222D0 (no) | Fremgangsmaater for behandling av profylakse av pneumocytis carinii pneumoni og andre sykdommer og forbindelser og formuleringer til anvendelse i nevnte metoder. | |
ES2036526T3 (es) | Composiciones de interferon. | |
ES2054207T3 (es) | Metodos de uso de 2-isopropil-2-fenilaminovaleronitrilos como inmunosupresores y vasodilatadores. | |
NO894008D0 (no) | Trekonserveringsmiddel og fremgangsmaate for behandling avtre med samme. | |
DE69623316T2 (de) | Ctla-8 in kombination mit g-csf oder mit g-csf und il-6, und verwendung vom ctla-8 zur behandlung von infektionen | |
DE68916777D1 (de) | Verwendung von TNF zur Herstellung eines Arzneimittels zur Behandlung von Psoriasis. | |
DE69131058T2 (de) | Verwendung einer therapeutischen Zusammensetzung zur Behandlung von Bronchitis | |
DK1007085T3 (da) | Anvendelse af væksthormon i præparater til behandling af insulin-resistens i hjertet | |
DK320589A (da) | Fremgangsmaade til hindring af vaekst af aerobe fungi i vandige carbonhydrider | |
DE3777411D1 (de) | Mittel zur verbesserung der perkutanen verabreichung von arzneimitteln. | |
DE58909779D1 (de) | Alkali- und erdalkalisalze des oxipurinols in amorpher oder kristalliner form als mittel zur behandlung von hyperurikämie und gicht |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 434094 Country of ref document: ES |