ATE87301T1 - N-acyl-n-naphthoylglycine als aldose-reductaseinhibitoren. - Google Patents
N-acyl-n-naphthoylglycine als aldose-reductaseinhibitoren.Info
- Publication number
- ATE87301T1 ATE87301T1 AT88312314T AT88312314T ATE87301T1 AT E87301 T1 ATE87301 T1 AT E87301T1 AT 88312314 T AT88312314 T AT 88312314T AT 88312314 T AT88312314 T AT 88312314T AT E87301 T1 ATE87301 T1 AT E87301T1
- Authority
- AT
- Austria
- Prior art keywords
- acyl
- reductase inhibitors
- aldose reductase
- naphthoylglycine
- naphthoylglycines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/66—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings being part of condensed ring systems and singly-bound oxygen atoms, bound to the same carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/62—Compounds containing any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylcarbamates
- C07C271/64—Y being a hydrogen or a carbon atom, e.g. benzoylcarbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/137,406 US4820727A (en) | 1987-12-23 | 1987-12-23 | N-acyl-N-naphthoylglycines as aldose reductase inhibitors |
EP19880312314 EP0322256B1 (de) | 1987-12-23 | 1988-12-23 | N-Acyl-N-naphthoylglycine als Aldose-Reductase-Inhibitoren |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE87301T1 true ATE87301T1 (de) | 1993-04-15 |
Family
ID=22477290
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88312314T ATE87301T1 (de) | 1987-12-23 | 1988-12-23 | N-acyl-n-naphthoylglycine als aldose-reductaseinhibitoren. |
Country Status (7)
Country | Link |
---|---|
US (1) | US4820727A (de) |
EP (1) | EP0322256B1 (de) |
JP (1) | JPH02502727A (de) |
AT (1) | ATE87301T1 (de) |
CA (1) | CA1326680C (de) |
DE (1) | DE3879650T2 (de) |
WO (1) | WO1989005793A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4925968A (en) * | 1987-12-23 | 1990-05-15 | American Home Products Corporation | N-acyl-N-naphthoylglycines as aldose reductase inhibitors |
JP4648546B2 (ja) * | 2001-01-10 | 2011-03-09 | 関東電化工業株式会社 | 反応活性な基を有する新規なナフタレン化合物及びそれらの製造方法 |
BRPI0414011A (pt) * | 2003-08-29 | 2006-10-24 | Pfizer | naftalencarboxamidas e seus derivados úteis como novos agentes antiangiogênicos |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1182472A (en) * | 1981-03-02 | 1985-02-12 | Kazimir Sestanj | N-[(2-naphthalenyl)thioxomethyl]glycine derivatives |
CA1176269A (en) * | 1981-03-02 | 1984-10-16 | Kazimir Sestanj | N-naphthoylglycine derivatives |
AU544067B2 (en) * | 1981-03-02 | 1985-05-16 | Wyeth-Ayerst Canada Inc. | Thioamides and amides. treatment of diabetes |
CA1191156A (en) * | 1981-10-15 | 1985-07-30 | Francesco Bellini | N-((6-(lower alkoxy)-5-(trifluoromethylthio)-1- naphthalenyl)-thioxomethyl)-n-(lower alkyl)glycines |
CA1147739A (en) * | 1981-03-02 | 1983-06-07 | Kazimir Sestanj | N-(naphthalenylthioxomethyl)aminoacid derivatives |
DE61906T1 (de) * | 1981-03-26 | 1983-05-26 | Inoue-Japax Research Inc., Yokohama, Kanagawa | Verfahren und vorrichtung zur bearbeitung eines werkstueckes mit energiereichen teilchen und ein auf diese weise bearbeitetes produkt. |
US4562286A (en) * | 1984-11-01 | 1985-12-31 | Occidental Chemical Corporation | Process for preparing methoxytrifluoromethylnaphthoic acid from dimethylnaphthalene |
US4672059A (en) * | 1985-06-10 | 1987-06-09 | American Home Products Corporation | N-[[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]-thioxomethyl and carbonyl]-N-methylglycinamides |
US4672058A (en) * | 1985-06-10 | 1987-06-09 | American Home Products Corporation | N[[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]-thioxomethyl]-N-methylglycinamides |
US4699993A (en) * | 1985-12-12 | 1987-10-13 | Ethyl Corporation | Perfluoroalkylnaphthalene compounds |
-
1987
- 1987-12-23 US US07/137,406 patent/US4820727A/en not_active Expired - Lifetime
-
1988
- 1988-12-19 CA CA000586305A patent/CA1326680C/en not_active Expired - Fee Related
- 1988-12-21 WO PCT/US1988/004625 patent/WO1989005793A1/en unknown
- 1988-12-21 JP JP1500653A patent/JPH02502727A/ja active Pending
- 1988-12-23 DE DE8888312314T patent/DE3879650T2/de not_active Expired - Fee Related
- 1988-12-23 EP EP19880312314 patent/EP0322256B1/de not_active Expired - Lifetime
- 1988-12-23 AT AT88312314T patent/ATE87301T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH02502727A (ja) | 1990-08-30 |
CA1326680C (en) | 1994-02-01 |
DE3879650D1 (en) | 1993-04-29 |
US4820727A (en) | 1989-04-11 |
WO1989005793A1 (en) | 1989-06-29 |
EP0322256A1 (de) | 1989-06-28 |
DE3879650T2 (de) | 1993-07-01 |
EP0322256B1 (de) | 1993-03-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |