ATE80911T1 - C-terminal-alpha-amidierendes enzym und verfahren zu dessen herstellung und verwendung. - Google Patents

C-terminal-alpha-amidierendes enzym und verfahren zu dessen herstellung und verwendung.

Info

Publication number
ATE80911T1
ATE80911T1 AT87304994T AT87304994T ATE80911T1 AT E80911 T1 ATE80911 T1 AT E80911T1 AT 87304994 T AT87304994 T AT 87304994T AT 87304994 T AT87304994 T AT 87304994T AT E80911 T1 ATE80911 T1 AT E80911T1
Authority
AT
Austria
Prior art keywords
terminal
production
molecular weight
methods
amidating enzyme
Prior art date
Application number
AT87304994T
Other languages
English (en)
Inventor
Hisayuki Matsuo
Kenzaku Mizuno
Original Assignee
Hisayuki Matsuo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisayuki Matsuo filed Critical Hisayuki Matsuo
Application granted granted Critical
Publication of ATE80911T1 publication Critical patent/ATE80911T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/17—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with reduced ascorbate as one donor, and incorporation of one atom of oxygen (1.14.17)
    • C12Y114/17003—Peptidylglycine monooxygenase (1.14.17.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
AT87304994T 1986-06-07 1987-06-05 C-terminal-alpha-amidierendes enzym und verfahren zu dessen herstellung und verwendung. ATE80911T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61131089A JPH0775541B2 (ja) 1986-06-07 1986-06-07 Ｃ末端アミド化酵素及びその製造方法
EP87304994A EP0249412B1 (de) 1986-06-07 1987-06-05 C-Terminal-alpha-amidierendes Enzym und Verfahren zu dessen Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE80911T1 true ATE80911T1 (de) 1992-10-15

Family

ID=15049719

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87304994T ATE80911T1 (de) 1986-06-07 1987-06-05 C-terminal-alpha-amidierendes enzym und verfahren zu dessen herstellung und verwendung.

Country Status (6)

Country Link
US (1) US4921797A (de)
EP (1) EP0249412B1 (de)
JP (1) JPH0775541B2 (de)
AT (1) ATE80911T1 (de)
DE (1) DE3781832T2 (de)
ES (1) ES2044928T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319685B1 (en) 1984-09-27 2001-11-20 Unigene Laboratories, Inc. Alpha-amidating enzyme compositions and processes for their production and use
JP2598050B2 (ja) * 1987-07-17 1997-04-09 サントリー株式会社 Ｃ−末端α−アミド化酵素
US5789234A (en) * 1987-08-14 1998-08-04 Unigene Laboratories, Inc. Expression systems for amidating enzyme
JP2653820B2 (ja) * 1988-03-14 1997-09-17 壽之 松尾 アミド化酵素及びその製造方法
JP2535398B2 (ja) * 1989-01-17 1996-09-18 サントリー株式会社 アミド化ペプチドの製造方法
JP2845468B2 (ja) * 1989-01-17 1999-01-13 サントリー株式会社 ヒト甲状腺由来Ｃ―末端α―アミド化酵素
ES2079054T3 (es) * 1990-06-01 1996-01-01 Ciba Geigy Ag Peptidilhidroxiglicina n-c-liasa y adn codificante de la misma.
US5580751A (en) * 1990-09-14 1996-12-03 Carlsberg A/S Process for the preparation of C-terminally amidated peptides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708934A (en) * 1984-09-27 1987-11-24 Unigene Laboratories, Inc. α-amidation enzyme
GB8515630D0 (en) * 1985-06-20 1985-07-24 Celltech Ltd Enzyme purification

Also Published As

Publication number Publication date
EP0249412A2 (de) 1987-12-16
EP0249412B1 (de) 1992-09-23
JPS62289184A (ja) 1987-12-16
EP0249412A3 (en) 1989-02-22
US4921797A (en) 1990-05-01
DE3781832T2 (de) 1993-04-01
JPH0775541B2 (ja) 1995-08-16
DE3781832D1 (de) 1992-10-29
ES2044928T3 (es) 1994-01-16

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time