ATE77074T1 - Verbindungen zur verwendung in der radiotherapie oder zur krebsvisualisierung. - Google Patents
Verbindungen zur verwendung in der radiotherapie oder zur krebsvisualisierung.Info
- Publication number
- ATE77074T1 ATE77074T1 AT88903292T AT88903292T ATE77074T1 AT E77074 T1 ATE77074 T1 AT E77074T1 AT 88903292 T AT88903292 T AT 88903292T AT 88903292 T AT88903292 T AT 88903292T AT E77074 T1 ATE77074 T1 AT E77074T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- cancer
- function
- radiotherapy
- targetted
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000001959 radiotherapy Methods 0.000 title abstract 2
- 238000012800 visualization Methods 0.000 title 1
- 238000003384 imaging method Methods 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- ZCYVEMRRCGMTRW-AHCXROLUSA-N Iodine-123 Chemical compound [123I] ZCYVEMRRCGMTRW-AHCXROLUSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
- 239000003270 steroid hormone Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0493—Steroids, e.g. cholesterol, testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8705524A FR2613937B1 (fr) | 1987-04-17 | 1987-04-17 | Ligands specifiques de recepteurs d'hormones steroides utiles pour la therapie ciblee ou l'imagerie medicale notamment du cancer |
| PCT/FR1988/000188 WO1988007986A2 (fr) | 1987-04-17 | 1988-04-15 | Composes utiles notamment pour la radiotherapie ou l'imagerie du cancer |
| EP88903292A EP0310645B1 (de) | 1987-04-17 | 1988-04-15 | Verbindungen zur verwendung in der radiotherapie oder zur krebsvisualisierung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE77074T1 true ATE77074T1 (de) | 1992-06-15 |
Family
ID=9350264
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88903292T ATE77074T1 (de) | 1987-04-17 | 1988-04-15 | Verbindungen zur verwendung in der radiotherapie oder zur krebsvisualisierung. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5096694A (de) |
| EP (1) | EP0310645B1 (de) |
| JP (1) | JP2708204B2 (de) |
| AT (1) | ATE77074T1 (de) |
| CA (1) | CA1325803C (de) |
| DE (1) | DE3871892T2 (de) |
| FR (1) | FR2613937B1 (de) |
| WO (1) | WO1988007986A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2637803B1 (fr) * | 1988-10-19 | 1993-07-09 | Ire Celltarg Sa | Ligands specifiques de recepteurs d'hormones steroides estrogenes et progestagenes, application et produits intermediaires de synthese |
| WO1990012321A1 (en) * | 1989-03-31 | 1990-10-18 | The Cancer Institute Board | Halogenated dna ligand radiosensitisers for cancer therapy |
| US5641764A (en) * | 1989-03-31 | 1997-06-24 | Peter Maccallum Institute | Halogenated DNA ligand radiosensitizers for cancer therapy |
| AU639920B2 (en) * | 1989-03-31 | 1993-08-12 | Anti-Cancer Council Of Victoria | Halogenated dna ligand radiosensitisers for cancer therapy |
| US5427766A (en) * | 1993-11-15 | 1995-06-27 | The Dow Chemical Company | Radiolabeled steroids for use in radiochemical-guided surgery |
| EP0757559A4 (de) * | 1994-04-29 | 1999-06-23 | Molecular Medicine Center | Zusammensetzung zur verabreichung von toxischen radioisotopen in den zellkern und ihre verwendung |
| US6238644B1 (en) | 1997-09-03 | 2001-05-29 | Wayne State University | Method for treating and/or imaging breast cancer using radioactive iodide |
| SE513149C2 (sv) * | 1997-12-05 | 2000-07-17 | Katarina Edwards | Läkemedelsdistributionssystem med tvåstegsmålsökning, till specifika celler eller vävnad och till dess cellkärna |
| US6547812B1 (en) | 2000-12-29 | 2003-04-15 | Advanced Cardiovascular Systems, Inc. | Radiation therapy using a radioactive implantable device and a radiosensitizer agent |
| US7220730B2 (en) * | 2003-09-25 | 2007-05-22 | Board Of Regents Of The University Of Nebraska | Cancer specific radiolabeled conjugates regulated by the cell cycle for the treatment and diagnosis of cancer |
| CN1321127C (zh) * | 2005-04-06 | 2007-06-13 | 江苏省原子医学研究所 | 碘(*i)－23－羟基白桦酸及其制备方法和应用 |
| WO2008109080A2 (en) * | 2007-03-01 | 2008-09-12 | Siemens Medical Solutions Usa, Inc. | Nucleoside based proliferation imaging markers |
| JP2014062054A (ja) * | 2012-09-20 | 2014-04-10 | Gyoseiin Genshino Iinkai Kakuno Kenkyusho | よう素−１２３標記チミン類似物［１２３Ｉ］−ＩａｒａＵのプローブ |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE518547C (de) * | 1931-02-17 | Buderus Eisenwerk | Verfahren zur Herstellung von Schleudergussrohren | |
| NL7405626A (nl) * | 1974-04-26 | 1975-10-28 | Akzo Nv | Nieuwe 11-gesubstitueerde steroiden van de oestraanreeks. |
| US4465676A (en) * | 1980-04-09 | 1984-08-14 | New England Nuclear Corporation | 16α Halogen substituted 3,17β-dihydroxy steroidal estrogens |
| US4541957A (en) * | 1983-09-07 | 1985-09-17 | The George Washington University | Process for preparing iodovinyl-estradiol |
| DE3337179A1 (de) * | 1983-10-10 | 1985-05-23 | Schering AG, 1000 Berlin und 4709 Bergkamen | Estran- und androstan-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende praeparate |
| JPS60126231A (ja) * | 1983-12-09 | 1985-07-05 | Seitai Kagaku Kenkyusho:Kk | 放射性診断剤 |
| DE3427795A1 (de) * | 1984-07-25 | 1986-02-06 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue 17(alpha)-halogenvinyl-estran-derivate, ihre herstellung und verwendung in der medizin |
| US4882141A (en) * | 1984-10-22 | 1989-11-21 | Bio-Medical Research Laboratories, Inc. | Tissue imaging utilizing labelled steroids |
| US5104637A (en) * | 1985-02-06 | 1992-04-14 | University Of Cincinnati | Radio labeled dihematophorphyrin ether and its use in detecting and treating neoplastic tissue |
| EP0263877A1 (de) * | 1986-04-11 | 1988-04-20 | The President And Fellows Of Harvard College | Dihydrorhodamine und halogenierte derivate daraus |
| FR2637803B1 (fr) * | 1988-10-19 | 1993-07-09 | Ire Celltarg Sa | Ligands specifiques de recepteurs d'hormones steroides estrogenes et progestagenes, application et produits intermediaires de synthese |
-
1987
- 1987-04-17 FR FR8705524A patent/FR2613937B1/fr not_active Expired
-
1988
- 1988-04-15 CA CA000564275A patent/CA1325803C/fr not_active Expired - Lifetime
- 1988-04-15 DE DE8888903292T patent/DE3871892T2/de not_active Expired - Lifetime
- 1988-04-15 WO PCT/FR1988/000188 patent/WO1988007986A2/fr not_active Ceased
- 1988-04-15 AT AT88903292T patent/ATE77074T1/de active
- 1988-04-15 EP EP88903292A patent/EP0310645B1/de not_active Expired - Lifetime
- 1988-04-15 JP JP63503500A patent/JP2708204B2/ja not_active Expired - Lifetime
- 1988-04-19 US US07/297,864 patent/US5096694A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2708204B2 (ja) | 1998-02-04 |
| WO1988007986A2 (fr) | 1988-10-20 |
| EP0310645A1 (de) | 1989-04-12 |
| DE3871892D1 (de) | 1992-07-16 |
| WO1988007986A3 (fr) | 1988-12-01 |
| FR2613937A1 (fr) | 1988-10-21 |
| US5096694A (en) | 1992-03-17 |
| FR2613937B1 (fr) | 1989-07-21 |
| DE3871892T2 (de) | 1993-02-04 |
| CA1325803C (fr) | 1994-01-04 |
| EP0310645B1 (de) | 1992-06-10 |
| JPH01503708A (ja) | 1989-12-14 |
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