ATE75732T1 - Verfahren zur herstellung von vitamin a. - Google Patents
Verfahren zur herstellung von vitamin a.Info
- Publication number
- ATE75732T1 ATE75732T1 AT88403017T AT88403017T ATE75732T1 AT E75732 T1 ATE75732 T1 AT E75732T1 AT 88403017 T AT88403017 T AT 88403017T AT 88403017 T AT88403017 T AT 88403017T AT E75732 T1 ATE75732 T1 AT E75732T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- production
- cis
- hydroquinone
- hydrogenation
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 abstract 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 abstract 1
- NCYCYZXNIZJOKI-OVSJKPMPSA-N Retinaldehyde Chemical compound O=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-OVSJKPMPSA-N 0.000 abstract 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 abstract 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 235000020945 retinal Nutrition 0.000 abstract 1
- 239000011604 retinal Substances 0.000 abstract 1
- JDNQPKBFOBQRBN-UHFFFAOYSA-N ruthenium monohydride Chemical compound [RuH] JDNQPKBFOBQRBN-UHFFFAOYSA-N 0.000 abstract 1
- 235000019155 vitamin A Nutrition 0.000 abstract 1
- 239000011719 vitamin A Substances 0.000 abstract 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 abstract 1
- 229940045997 vitamin a Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8716629A FR2623805B1 (fr) | 1987-12-01 | 1987-12-01 | Procede de preparation de la vitamine a |
| EP88403017A EP0319407B1 (fr) | 1987-12-01 | 1988-11-30 | Procédé de préparation de la vitamine A |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE75732T1 true ATE75732T1 (de) | 1992-05-15 |
Family
ID=9357335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88403017T ATE75732T1 (de) | 1987-12-01 | 1988-11-30 | Verfahren zur herstellung von vitamin a. |
Country Status (10)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5521221A (en) * | 1991-04-09 | 1996-05-28 | Sloan-Kettering Institute For Cancer Research | Retro-α-retinol (4,14-retro-retinol) derivatives and uses of retro-α-retinol |
| FR2715932B1 (fr) * | 1994-02-04 | 1996-03-15 | Rhone Poulenc Nutrition Animal | Procédé de préparation de la vitamine A et nouveaux intermédiaires. |
| US5648091A (en) * | 1994-08-03 | 1997-07-15 | The Proctor & Gamble Company | Stable vitamin A encapsulated |
| US5426248A (en) * | 1994-08-03 | 1995-06-20 | The Procter & Gamble Company | Stable vitamin A |
| WO2004047523A2 (en) * | 2002-11-26 | 2004-06-10 | Sato Gordon H | Microbial feedstock for filter feeding aquatic organisms |
| EP3019459B1 (en) * | 2013-07-08 | 2018-08-22 | DSM IP Assets B.V. | Selective transfer hydrogenation of retinal |
| CN111004163B (zh) * | 2019-11-13 | 2021-12-10 | 万华化学集团股份有限公司 | 一种钌催化剂催化维生素a异构化的方法 |
| CN113801049B (zh) * | 2021-08-30 | 2022-08-05 | 万华化学集团股份有限公司 | 一种一锅法制备β-胡萝卜素的方法 |
| WO2023099791A1 (en) * | 2021-12-03 | 2023-06-08 | Dsm Ip Assets B.V. | Novel compositions comprising trans retinol |
| WO2024119170A2 (en) * | 2022-12-02 | 2024-06-06 | Dsm Ip Assets B.V. | Fermentatively-produced retinoid containing compositions, and the methdos of making and using the same |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3210427A (en) * | 1965-10-05 | Method of producing aldehyde of transjtrans-z.g xvitamin | ||
| US2834813A (en) * | 1953-04-21 | 1958-05-13 | Ortho Pharma Corp | Synthesis of vitamin a |
| US2839585A (en) * | 1955-04-05 | 1958-06-17 | Eastman Kodak Co | Conversion of retinene-phenolic material complexes to vitamin a |
| NL99527C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1955-09-14 | |||
| US3499044A (en) * | 1967-11-07 | 1970-03-03 | Eastman Kodak Co | Method of preparing mixed isomers of vitamin a |
| CH518891A (de) * | 1969-07-04 | 1972-02-15 | Hoffmann La Roche | Verfahren zur selektiven Hydrierung von mindestens eine Dreifachbindung aufweisenden organischen Verbindungen |
| CH576926A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-03-21 | 1976-06-30 | Hoffmann La Roche | |
| US4268454A (en) * | 1978-12-21 | 1981-05-19 | Allied Chemical Corporation | Anionic group VIII metal hydride catalysts |
| US4321414A (en) * | 1980-08-26 | 1982-03-23 | The Halcon Sd Group, Inc. | Catalytic hydrogenation of glycolaldehyde to produce ethylene glycol |
| DE3471092D1 (en) * | 1983-03-09 | 1988-06-16 | Firmenich & Cie | Composition essentially consisting of trans-1-(2,6,6-trimethylcyclohexyl)-hexan-3-ol, utilization of same and process for its preparation; cycloaliphatic ketone and alcohol intermediates |
| SU1141170A1 (ru) * | 1983-06-28 | 1985-02-23 | Центральный Научно-Исследовательский И Проектно-Экспериментальный Институт Организации,Механизации И Технической Помощи Строительству Госстроя Ссср | Монтажна площадка |
-
1987
- 1987-12-01 FR FR8716629A patent/FR2623805B1/fr not_active Expired - Lifetime
-
1988
- 1988-11-29 JP JP63299778A patent/JPH07116133B2/ja not_active Expired - Lifetime
- 1988-11-29 US US07/277,199 patent/US4906795A/en not_active Expired - Fee Related
- 1988-11-29 KR KR1019880015759A patent/KR950008765B1/ko not_active Expired - Fee Related
- 1988-11-30 AT AT88403017T patent/ATE75732T1/de not_active IP Right Cessation
- 1988-11-30 EP EP88403017A patent/EP0319407B1/fr not_active Expired - Lifetime
- 1988-11-30 CA CA000584618A patent/CA1312872C/fr not_active Expired - Fee Related
- 1988-11-30 ES ES198888403017T patent/ES2032047T3/es not_active Expired - Lifetime
- 1988-11-30 DE DE8888403017T patent/DE3870821D1/de not_active Expired - Fee Related
-
1992
- 1992-05-07 GR GR920400049T patent/GR3004508T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3870821D1 (de) | 1992-06-11 |
| FR2623805B1 (fr) | 1990-04-13 |
| ES2032047T3 (es) | 1993-01-01 |
| KR890009381A (ko) | 1989-08-01 |
| EP0319407A1 (fr) | 1989-06-07 |
| KR950008765B1 (ko) | 1995-08-08 |
| JPH02275A (ja) | 1990-01-05 |
| CA1312872C (fr) | 1993-01-19 |
| US4906795A (en) | 1990-03-06 |
| GR3004508T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1993-04-28 |
| EP0319407B1 (fr) | 1992-05-06 |
| JPH07116133B2 (ja) | 1995-12-13 |
| FR2623805A1 (fr) | 1989-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |