DE3870821D1 - Verfahren zur herstellung von vitamin a. - Google Patents

Verfahren zur herstellung von vitamin a.

Info

Publication number
DE3870821D1
DE3870821D1 DE8888403017T DE3870821T DE3870821D1 DE 3870821 D1 DE3870821 D1 DE 3870821D1 DE 8888403017 T DE8888403017 T DE 8888403017T DE 3870821 T DE3870821 T DE 3870821T DE 3870821 D1 DE3870821 D1 DE 3870821D1
Authority
DE
Germany
Prior art keywords
producing vitamin
vitamin
cis
hydroquinone
hydrogenation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888403017T
Other languages
English (en)
Inventor
Jean-Michel Grosselin
Claude Mercier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of DE3870821D1 publication Critical patent/DE3870821D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE8888403017T 1987-12-01 1988-11-30 Verfahren zur herstellung von vitamin a. Expired - Fee Related DE3870821D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8716629A FR2623805B1 (fr) 1987-12-01 1987-12-01 Procede de preparation de la vitamine a

Publications (1)

Publication Number Publication Date
DE3870821D1 true DE3870821D1 (de) 1992-06-11

Family

ID=9357335

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888403017T Expired - Fee Related DE3870821D1 (de) 1987-12-01 1988-11-30 Verfahren zur herstellung von vitamin a.

Country Status (10)

Country Link
US (1) US4906795A (de)
EP (1) EP0319407B1 (de)
JP (1) JPH07116133B2 (de)
KR (1) KR950008765B1 (de)
AT (1) ATE75732T1 (de)
CA (1) CA1312872C (de)
DE (1) DE3870821D1 (de)
ES (1) ES2032047T3 (de)
FR (1) FR2623805B1 (de)
GR (1) GR3004508T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5521221A (en) * 1991-04-09 1996-05-28 Sloan-Kettering Institute For Cancer Research Retro-α-retinol (4,14-retro-retinol) derivatives and uses of retro-α-retinol
FR2715932B1 (fr) * 1994-02-04 1996-03-15 Rhone Poulenc Nutrition Animal Procédé de préparation de la vitamine A et nouveaux intermédiaires.
US5648091A (en) * 1994-08-03 1997-07-15 The Proctor & Gamble Company Stable vitamin A encapsulated
US5426248A (en) * 1994-08-03 1995-06-20 The Procter & Gamble Company Stable vitamin A
JP2006507826A (ja) * 2002-11-26 2006-03-09 ゴードン エイチ サトー ろ過摂食水性有機体用の微生物飼料
WO2015004117A1 (en) * 2013-07-08 2015-01-15 Dsm Ip Assets B. V. Selective transfer hydrogenation of retinal
CN111004163B (zh) * 2019-11-13 2021-12-10 万华化学集团股份有限公司 一种钌催化剂催化维生素a异构化的方法
CN113801049B (zh) * 2021-08-30 2022-08-05 万华化学集团股份有限公司 一种一锅法制备β-胡萝卜素的方法
WO2023099791A1 (en) * 2021-12-03 2023-06-08 Dsm Ip Assets B.V. Novel compositions comprising trans retinol

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3210427A (en) * 1965-10-05 Method of producing aldehyde of transjtrans-z.g xvitamin
US2834813A (en) * 1953-04-21 1958-05-13 Ortho Pharma Corp Synthesis of vitamin a
US2839585A (en) * 1955-04-05 1958-06-17 Eastman Kodak Co Conversion of retinene-phenolic material complexes to vitamin a
NL99527C (de) * 1955-09-14
US3499044A (en) * 1967-11-07 1970-03-03 Eastman Kodak Co Method of preparing mixed isomers of vitamin a
CH518891A (de) * 1969-07-04 1972-02-15 Hoffmann La Roche Verfahren zur selektiven Hydrierung von mindestens eine Dreifachbindung aufweisenden organischen Verbindungen
CH576926A5 (de) * 1973-03-21 1976-06-30 Hoffmann La Roche
US4268454A (en) * 1978-12-21 1981-05-19 Allied Chemical Corporation Anionic group VIII metal hydride catalysts
US4321414A (en) * 1980-08-26 1982-03-23 The Halcon Sd Group, Inc. Catalytic hydrogenation of glycolaldehyde to produce ethylene glycol
DE3471092D1 (en) * 1983-03-09 1988-06-16 Firmenich & Cie Composition essentially consisting of trans-1-(2,6,6-trimethylcyclohexyl)-hexan-3-ol, utilization of same and process for its preparation; cycloaliphatic ketone and alcohol intermediates
SU1141170A1 (ru) * 1983-06-28 1985-02-23 Центральный Научно-Исследовательский И Проектно-Экспериментальный Институт Организации,Механизации И Технической Помощи Строительству Госстроя Ссср Монтажна площадка

Also Published As

Publication number Publication date
JPH02275A (ja) 1990-01-05
KR890009381A (ko) 1989-08-01
US4906795A (en) 1990-03-06
ATE75732T1 (de) 1992-05-15
FR2623805A1 (fr) 1989-06-02
KR950008765B1 (ko) 1995-08-08
CA1312872C (fr) 1993-01-19
JPH07116133B2 (ja) 1995-12-13
FR2623805B1 (fr) 1990-04-13
ES2032047T3 (es) 1993-01-01
EP0319407A1 (de) 1989-06-07
EP0319407B1 (de) 1992-05-06
GR3004508T3 (de) 1993-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee