ATE74440T1 - Verwendung von polyoxyaethylenaethern zur verbesserung der resultate von immunologischen analysen, die peroxidase-konjugate verwenden. - Google Patents

Verwendung von polyoxyaethylenaethern zur verbesserung der resultate von immunologischen analysen, die peroxidase-konjugate verwenden.

Info

Publication number
ATE74440T1
ATE74440T1 AT88901703T AT88901703T ATE74440T1 AT E74440 T1 ATE74440 T1 AT E74440T1 AT 88901703 T AT88901703 T AT 88901703T AT 88901703 T AT88901703 T AT 88901703T AT E74440 T1 ATE74440 T1 AT E74440T1
Authority
AT
Austria
Prior art keywords
improve
polyoxyaethylene
ethers
results
peroxidase conjugates
Prior art date
Application number
AT88901703T
Other languages
English (en)
Inventor
Alan Robert Craig
Thomas Peter Hartz Jr
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of ATE74440T1 publication Critical patent/ATE74440T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/571—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/962—Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT88901703T 1987-03-30 1988-01-28 Verwendung von polyoxyaethylenaethern zur verbesserung der resultate von immunologischen analysen, die peroxidase-konjugate verwenden. ATE74440T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/031,932 US4810630A (en) 1987-03-30 1987-03-30 Use of polyoxyethylene ethers to improve the performance of immunoassays employing peroxidase conjugates
EP88901703A EP0352264B1 (de) 1987-03-30 1988-01-28 Verwendung von polyoxyäthylenäthern zur verbesserung der resultate von immunologischen analysen, die peroxidase-konjugate verwenden
PCT/US1988/000193 WO1988007683A1 (en) 1987-03-30 1988-01-28 Use of polyoxyethylene ethers to improve the performance of immunoassays employing peroxidase conjugates

Publications (1)

Publication Number Publication Date
ATE74440T1 true ATE74440T1 (de) 1992-04-15

Family

ID=21862184

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88901703T ATE74440T1 (de) 1987-03-30 1988-01-28 Verwendung von polyoxyaethylenaethern zur verbesserung der resultate von immunologischen analysen, die peroxidase-konjugate verwenden.

Country Status (7)

Country Link
US (1) US4810630A (de)
EP (1) EP0352264B1 (de)
JP (1) JPH02503029A (de)
AT (1) ATE74440T1 (de)
CA (1) CA1292181C (de)
DE (1) DE3869775D1 (de)
WO (1) WO1988007683A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5470711A (en) * 1986-03-26 1995-11-28 Synbiotics Corporation Saliva enhancement reagent for feline leukemia virus elisa
DE3717402A1 (de) * 1987-05-23 1988-12-08 Behringwerke Ag Verfahren zur bestimmung von proteinen und mittel dazu
US5571667A (en) * 1987-10-01 1996-11-05 Chu; Albert E. Elongated membrane flow-through diagnostic device and method
US5032504A (en) * 1988-10-07 1991-07-16 Eastman Kodak Company Diagnostic test kit and method for determination of chlamydial or gonococcal antigens using a microporous membrane
JP2684069B2 (ja) * 1988-10-13 1997-12-03 昇一 首藤 免疫学的活性物質の測定方法及びそのための試薬
US4978632A (en) * 1988-12-15 1990-12-18 Kallestad Diagnostics, Inc. Method of pre-treating samples in peroxidase-catalyzed enzyme assays
US5210039A (en) * 1989-02-09 1993-05-11 Eastman Kodak Company Wash composition, test kit and their use to determine a herpes simplex viral antigen
US5124245A (en) * 1989-02-09 1992-06-23 Eastman Kodak Company Wash composition, test kit and their use to determine a herpes simplex viral antigen
CA2028146A1 (en) * 1989-03-01 1990-09-02 Chester H. Warren Iii Composition containing labeled streptococcal antibody, test kit and assay using same
US6352863B1 (en) 1990-01-19 2002-03-05 La Mina, Inc. Assay device
US5244815A (en) * 1990-01-19 1993-09-14 Lamina Ltd. Fingerprint test pad and method for fingerprinting using particle based immunoassay
DE4035174A1 (de) * 1990-11-06 1992-05-07 Biotest Ag Verfahren zur bestimmung von proteinen in koerperfluessigkeiten und mittel zur durchfuehrung des verfahrens
DE4037764A1 (de) * 1990-11-28 1992-06-04 Behringwerke Ag Waschloesung fuer festphasen-immunometrische verfahren, die stabilisatoren fuer das markierungssystem enthaelt und ihre verwendung
WO1992012429A1 (fr) * 1991-01-10 1992-07-23 Teijin Limited Analyse a sensibilite elevee de facteur tissulaire et kit utilise a cet effet
EP0650044A3 (de) * 1993-04-02 1996-06-19 Hitachi Chemical Co Ltd Verfahren zur Chemilumineszenzanalyse.
DE4435728A1 (de) * 1994-01-19 1995-07-20 Boehringer Mannheim Gmbh Biotinsilan-Verbindungen und diese Verbindungen enthaltende Bindematrix
US5627080A (en) * 1994-07-29 1997-05-06 Beckman Instruments, Inc. Detergent-facilitated immunoassay for the rapid and quantitative assay of pharmacological agents
US5639626A (en) * 1994-11-15 1997-06-17 Chiron Diagnostics Corporation Reagents for specific binding assays
GB9515855D0 (en) * 1995-08-02 1995-10-04 Centocor U K Limited A specimen dilution indicator system for use in clinical diagnostic assays
US6015716A (en) * 1996-07-12 2000-01-18 The Liposome Company, Inc. Detection of endotoxin levels in liposomes, lipid bilayers and lipid complexes
DE19748489A1 (de) 1997-11-03 1999-05-06 Roche Diagnostics Gmbh Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
US6284194B1 (en) 1998-03-11 2001-09-04 Albert E. Chu Analytical assay device and methods using surfactant treated membranes to increase assay sensitivity
US7678578B2 (en) * 2005-02-07 2010-03-16 Beckman Coulter, Inc. Cell permeabilization and stabilization reagent and method of use
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
US7879623B2 (en) * 2006-03-31 2011-02-01 Guirguis Raouf A Integrated device for analyte, testing, confirmation, and donor identity verification
US11906512B2 (en) 2006-03-31 2024-02-20 Zeus Diagnostics, LLC Integrated device for analyte testing, confirmation, and donor identity verification
US7741103B2 (en) * 2006-03-31 2010-06-22 Guirguis Raouf A Integrated screening and confirmation device
US8940527B2 (en) * 2006-03-31 2015-01-27 Lamina Equities Corp. Integrated device for analyte testing, confirmation, and donor identity verification
EP2041573B1 (de) * 2006-06-23 2019-09-04 PerkinElmer Health Sciences, Inc. Verfahren und vorrichtung für mikrofluidische point-of-care-immunoassays
WO2010083417A1 (en) * 2009-01-16 2010-07-22 Angros Lee H Encapsulated reagents and methods of use
JP5791634B2 (ja) 2010-01-29 2015-10-07 マイクロニクス， インコーポレイテッド サンプル−回答型のマイクロ流体カートリッジ
EP2802417B1 (de) 2012-01-09 2019-05-15 Micronics, Inc. Mikrofluidisches reaktorsystem
JP6498125B2 (ja) 2012-12-21 2019-04-10 マイクロニクス， インコーポレイテッド 流体回路および関連する製造方法
US20150346097A1 (en) 2012-12-21 2015-12-03 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
JP6935167B2 (ja) 2012-12-21 2021-09-15 ペルキネルマー ヘルス サイエンシーズ， インコーポレイテッド マイクロ流体使用のための低弾性フィルム
US10386377B2 (en) 2013-05-07 2019-08-20 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
WO2014182847A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Device for preparation and analysis of nucleic acids
AU2014262710B2 (en) 2013-05-07 2019-09-12 Perkinelmer Health Sciences, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
US10527618B2 (en) * 2013-09-10 2020-01-07 Denka Seiken Co., Ltd. Sample processing method for influenza virus immunoassay, and immunoassay method
US10564155B2 (en) 2017-01-27 2020-02-18 Raouf A Guirguis Dual swab fluid sample collection for split sample testing and fingerprint identification device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0061541A1 (de) * 1981-03-27 1982-10-06 Biospecia Limited Immunologische Analyse und biochemisches Mittel hierfür
JPS58187862A (ja) * 1982-04-27 1983-11-02 Sanyo Chem Ind Ltd 免疫測定改良剤および改良方法
US4454232A (en) * 1982-06-07 1984-06-12 Bio-Rad Laboratories, Inc. Estriol assay
US4525452A (en) * 1983-01-24 1985-06-25 Btc Diagnostics Limited Partnership Enzyme immunoassay with step of immersing sample in deionized water

Also Published As

Publication number Publication date
EP0352264A4 (de) 1990-02-20
EP0352264B1 (de) 1992-04-01
JPH02503029A (ja) 1990-09-20
EP0352264A1 (de) 1990-01-31
WO1988007683A1 (en) 1988-10-06
DE3869775D1 (de) 1992-05-07
US4810630A (en) 1989-03-07
CA1292181C (en) 1991-11-19

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee