ATE71529T1 - Pharmazeutische praeparate zur transdermalen applikation von heparin. - Google Patents
Pharmazeutische praeparate zur transdermalen applikation von heparin.Info
- Publication number
- ATE71529T1 ATE71529T1 AT89102823T AT89102823T ATE71529T1 AT E71529 T1 ATE71529 T1 AT E71529T1 AT 89102823 T AT89102823 T AT 89102823T AT 89102823 T AT89102823 T AT 89102823T AT E71529 T1 ATE71529 T1 AT E71529T1
- Authority
- AT
- Austria
- Prior art keywords
- heparin
- transdermal application
- pharmaceutical preparations
- addition
- choline
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002897 heparin Drugs 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 abstract 1
- 229960001231 choline Drugs 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 239000003883 ointment base Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3805523A DE3805523A1 (de) | 1988-02-22 | 1988-02-22 | Pharmazeutische praeparate zur transdermalen applikation von heparin |
| EP89102823A EP0331948B1 (de) | 1988-02-22 | 1989-02-18 | Pharmazeutische Präparate zur transdermalen Applikation von Heparin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE71529T1 true ATE71529T1 (de) | 1992-02-15 |
Family
ID=6347919
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89102823T ATE71529T1 (de) | 1988-02-22 | 1989-02-18 | Pharmazeutische praeparate zur transdermalen applikation von heparin. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0331948B1 (de) |
| AT (1) | ATE71529T1 (de) |
| DE (2) | DE3805523A1 (de) |
| DK (1) | DK79289A (de) |
| ES (1) | ES2040391T3 (de) |
| GR (1) | GR3003666T3 (de) |
| IE (1) | IE61287B1 (de) |
| PT (1) | PT89781B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9302135D0 (sv) * | 1993-06-18 | 1993-06-18 | Kabi Pharmacia Ab | New pharmaceutical composition |
| RU2107492C1 (ru) * | 1997-01-22 | 1998-03-27 | Открытое акционерное общество "Нижегородский химико-фармацевтический завод" | Мазь для лечения тромбофлебита |
| ITMI20042505A1 (it) * | 2004-12-24 | 2005-03-24 | Oro Consulting S R L | Sostanza emulsionante e-o tensioattiva ad attivita' battericida per la preparazione di emulsioni e di tensidi per uso dermofarmaceutico e cosmetico emulsioni e tensidi preparati con questa sostanzaa prodotto dermofarmaceutico e prodotto cosmetico ott |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4729989A (en) * | 1985-06-28 | 1988-03-08 | Merck & Co., Inc. | Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts |
| US4692441A (en) * | 1985-08-16 | 1987-09-08 | Merck & Co., Inc. | Chorine esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities |
-
1988
- 1988-02-22 DE DE3805523A patent/DE3805523A1/de not_active Withdrawn
-
1989
- 1989-02-18 EP EP89102823A patent/EP0331948B1/de not_active Expired - Lifetime
- 1989-02-18 AT AT89102823T patent/ATE71529T1/de not_active IP Right Cessation
- 1989-02-18 DE DE8989102823T patent/DE68900693D1/de not_active Expired - Fee Related
- 1989-02-18 ES ES89102823T patent/ES2040391T3/es not_active Expired - Lifetime
- 1989-02-20 IE IE53789A patent/IE61287B1/en not_active IP Right Cessation
- 1989-02-21 DK DK079289A patent/DK79289A/da not_active Application Discontinuation
- 1989-02-22 PT PT89781A patent/PT89781B/pt not_active IP Right Cessation
-
1992
- 1992-01-29 GR GR920400096T patent/GR3003666T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE890537L (en) | 1989-08-22 |
| PT89781A (pt) | 1989-10-04 |
| DE68900693D1 (de) | 1992-02-27 |
| IE61287B1 (en) | 1994-10-19 |
| DK79289A (da) | 1989-08-23 |
| DE3805523A1 (de) | 1989-10-05 |
| EP0331948A3 (en) | 1990-02-07 |
| PT89781B (pt) | 1994-05-31 |
| GR3003666T3 (de) | 1993-03-16 |
| EP0331948B1 (de) | 1992-01-15 |
| DK79289D0 (da) | 1989-02-21 |
| ES2040391T3 (es) | 1996-07-16 |
| EP0331948A2 (de) | 1989-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |